Online Market Research Research Articles

Integrating green image with relationship marketing: A moderating role of green image

This study integrates social exchange theory, the biophilia hypothesis, the hierarchy of effects model, and self-congruency theory to examine how relational benefits and green image influence positive emotion, customer loyalty, and customer green behavior (CGB). Data were collected from 314 respondents via an online marketing research firm and analyzed using SmartPLS 4.0. The results show that customers’ perceptions of relational benefits have a direct impact on both customer loyalty and positive emotions. While green image significantly affects customer loyalty, it does not have a direct impact on positive emotions or CGB. However, green image enhances the positive association between customer emotions and CGB, suggesting that customers are more likely to engage in green behavior when they feel a positive emotional connection with a company they perceive as environmentally responsible. These findings suggest that restaurant firms should implement marketing strategies to improve their green image by emphasizing the value of relational benefits. Both theoretical and managerial implications are discussed.

A Differential Analysis of Preferred Feminine Facial Contours for Transfeminine Individuals.

Facial feminization surgeries are important gender-affirming procedures for transfeminine individuals. The literature provides guidance on classically feminine facial features but the aesthetic preferences of transgender patients have not been studied. This study aimed to define the preferred feminine facial proportions of transfeminine patients and compare them to a mixed population of US adults. An online survey was designed consisting of virtually modified images with progressive degrees of change in 6 facial features: forehead, nasal dorsum, chin projection, nasolabial angle, mandibular angle, and chin height. It was administered to transfeminine patients in a large-scale health system as well as the general population using an online market research instrument. Respondents ranked each image on a 7-point Likert scale from "very unattractive" to "very attractive" for a feminine face. Both groups agreed that a moderately convex forehead without supraorbital ridge prominence, slightly sloped nasal dorsum, ∼105-degree nasolabial angle, and decreased chin height were considered most attractive. In addition, very concave nasal slope and ∼110-degree nasolabial angle were rated significantly higher by transfeminine respondents compared with controls. The most classically masculine versions of each feature were considered significantly more unattractive by transfeminine patients when compared with controls. Transfeminine individuals share significant preferences in feminine facial features with control respondents. However, transfeminine patients were more averse to traditionally masculine features on a feminine face and more accepting of the most traditionally feminine versions of nasal contours. Understanding these differences can facilitate surgical planning between surgeons and patients and potentially improve patient satisfaction.

Examining Customer Value Cocreation Behavior in Boutique Hotels: Hospitableness, Perceived Value, Satisfaction, and Citizenship Behavior

Distinguished from the goods-dominant logic, service-dominant logic has suggested customers are value cocreators. However, in boutique hotels where services are highly individualized and interactive between hotel staff and customers, the role of customer value cocreating might be different compared to a normal service encounter. Yet limited studies have demonstrated whether customers’ value cocreation behaviors have changed in boutique hotels and its corresponding mechanism. This study aims to fulfill this gap by examining customer value cocreation behavior (i.e., citizenship behavior via feedback, advocacy, helping and tolerance) from the impact of hospitableness (personalization, warm welcome, deeper connection, and comfort), perceived value, and satisfaction. Data were obtained in China via an online marketing research panel. Results from confirmatory factor analysis (CFA) and structural equation modelling (SEM) showed that both hospitableness and perceived value positively affect satisfaction, while perceived value also partially mediates the relationship between hospitableness and satisfaction. An interesting finding indicates that satisfaction impacts citizenship behavior in a following descending order: advocacy, feedback, helping, and tolerance. Two demographic variables (i.e., marital status, household incomes) were found to moderate the relationship between satisfaction and citizenship behavior. This study contributes to the literature on service-dominant logic, value cocreation, and boutique guest experiences. Managerial implications for facilitating the value cocreation process are also discussed.

Examining attributes of retailers that influence where cannabis is purchased: a discrete choice experiment

BackgroundWith the legalization of cannabis in Canada, consumers are presented with numerous purchase options. Licensed retailers are limited by the Cannabis Act and provincial regulations with respect to offering sales, advertising, location, maximum quantities, and information sharing in an effort to protect public health and safety. The degree these policies influence consumer purchase behavior will help inform regulatory refinement.MethodsA discrete choice experiment within a cross-sectional online survey was used to explore trade-offs consumers make when deciding where to purchase cannabis. Attributes included availability of sales/discounts, proximity, product information, customer service, product variety, and provincial regulation. Participants ≥ 19 years old who lived in Canada and purchased cannabis in the previous 12 months were recruited through an online market research survey panel. A multinomial logit (MNL) model was used for the base model, and latent class analysis was used to assess preference sub-groups. Key limitations included ordering effect, hypothetical bias, and framing effect.ResultsThe survey was completed by 1626 people, and the base model showed that customer service carried the most weight in purchase decisions, followed by proximity and availability of sales and discounts. There was considerable heterogeneity in preference patterns, with a five-group latent class model demonstrating best fit. Only one group (15% of sample) placed a high value on the store being provincially regulated, while three groups were willing to make a trade-off with regulation to access better customer service, product information, or closer proximity. One group preferred non-regulated sources (24% of sample); this group was also primarily driven by the availability of sales and discounts. Three groups (60.5% of sample) preferred online stores.ConclusionThis study highlighted that there exists significant diversity with respect to the influence of consumer experiences on cannabis purchase behaviors. Modifications to cannabis retail regulations that focus on improving access to product information as well as reviewing limitations on sales and discounts could have the most impact for shifting customers to licensed retailers.

Entrepreneurs’ preferences towards online market research packages: A discrete choice analysis

Startups have become a buzzword in the last couple of years, and entrepreneurship became career path for a number of people in the world. With all the advances in education and government subsidizing all over the world, still, statistics shows only a small percentage of successful startups. Studies have shown that the one the leading reasons for startup failure is the misreading of market?s needs. The aim of this paper is to determine the approach to market research, knowledge of tools and methods, and preferences towards online market research tools of entrepreneurs by using Discrete Choice Analysis. The research gathered 187 valid responses from a panel of participants working on developing new products and business, using an online survey tool. In the paper it is shown that the most important attributes for entrepreneurs are the price of the market research tool, followed by the level of details in the report generated, with more in-depth analysis regarding segmentation, simulations, and Marginal Willingness to Pay in the further chapters. The results of the research imply the need for a market research business model optimized for those starting a new business, focused primarily on detailed reporting and analysis, with the pricing model adjusted to the lack of resources entrepreneurs face at the start of their ventures, which would help them better understand the market-fit at the beginning and raise the statistic of successful startups.

Analisis Bibliometrik Terhadap Online Marketing

The technological of the internet has increased the demand for online marketing strategies. Over the years, online marketing has received a lot of attention because of the benefits for both personal and organizational. This study attempts to analyze online marketing from 2018 to 2022 through a bibliometric analysis procedure. A total of 200 articles were published retrieved from the Google Scholar database for analysis. The purpose of this study is to analyze developments research related to online marketing that will be useful later for recommendations for further research. This study uses a quantitative method take advantage of Publish or Perish software, Google Scholar, VOSViewer and Mendeley. This research is conducted to see how the consumers’ brand perception and purchasing decisions are influenced by different online marketing tools used such as components of online marketing. This is one of the pioneering studies which provides a greater explanation of online marketing research by investigating its evolution through bibliometric analysis.Keywords: Bibliometric Analysis; E-Commerce; Online Marketing; Social media

Looking Back on Your Travel Memories: Effects of Memorable Tourism Experiences on Well-being Via Daily Recovery Experiences

This study aims to examine memorable tourism experiences and their role in subsequent well-being. To achieve this, we carried out longitudinal surveys during the winter vacation period, recruiting participants via an online marketing research company. A total of 230 participants completed questionnaires comprising questions seeking demographic information and psychological scales at four time points so that the changes in their well-being could be assessed. Our findings indicate that having a memorable experience during a vacation had positive influences not only on the recovery experience at that time, but also on the recovery experience during subsequent daily life. Although the recovery experience during and after the vacation was profoundly involved, it should be noted that only the recovery experience after returning to everyday life was further associated with individuals' wellbeing. The results demonstrate new findings on how extraordinary experiences during vacations influence commonplace activities.

TEACHING EYE-TRACKING AND FACIAL EXPRESSION ANALYSIS TECHNOLOGY IN AN ONLINE MARKETING RESEARCH CLASS

ABSTRACT Technology continues to change and improve the marketing profession. Marketing research technologies such as eye-tracking and facial expression analysis allow marketers to gain more insights into consumer behaviors. Recently, these technologies have become more affordable and applicable in the classroom learning environment. A very recent addition to these technologies is the ability to collect eye-tracking and facial expression data remotely through a compliant user’s webcam. This paper illustrates how marketing educators can incorporate eye-tracking and facial expression analysis technology into an online marketing research class. The teaching effectiveness results show that this 4-week online project using the remote technology helps students improve their learning and become more ready for future careers. The online experiential project using these technologies allows marketing educators to switch from face-to-face instruction to an online format while still maintaining the same quality of instruction and level of engagement.

The impact of influenza on the ability to work, volunteer and provide care: results from an online survey of Canadian adults 50 years and older

BackgroundInfluenza is associated with a decline in functional abilities among Canadian older adults, although specific impacts on daily life have not been fully explored.MethodsIn August 2019 and May 2020, we conducted surveys of Canadian adults 50-64 years and 65 years and older through an online market research platform. The survey included questions about the impact of diagnosed influenza or self-reported influenza-like-illness (ILI) on working, volunteering and caregiving.ResultsWe surveyed 1006 adults in the 50-64 year age group about the 2018/19 season and 1001 about the 2019/20 season. In the 65 years and older age group, we surveyed 3548 and 3500 individuals about the 2018/19 and 2019/20 influenza seasons, respectively. In each season, nearly two-thirds of individuals 50-64 years with influenza/ILI were employed; 51.7% reported absenteeism in 2018/19 and 53.6% in 2019/20. Of the 20% of individuals 65 years and older who were employed, 47.0% of those with influenza/ILI were absent while ill in 2018/19 (39.8% in 2019/20). In 2018/2019, 29.6% of respondents 50-64 years old with influenza/ILI identified as volunteers (29.3% in 2019/2020). In both seasons, nearly half were unable to do so while ill. Of the 164 (32.7%) individuals 65 years and older who volunteered during the 2018/19 season, 80 (48.8%) did not while ill; 224 (37.3%) respondents volunteered in the 2019/20 season, and half were absent while ill. Of those 50-64 years with influenza/ILI, 97 (42.2%) and 57 (22.2%) were caregivers in 2018/19 and 2019/20, respectively. In 2018/19 and 2019/20, 40 (41.2%) and 28 (49.1%) caregivers were unable to provide care when ill, respectively. Of those with influenza/ILI in the 65 years and older age group, 123 (24.6%) and 162 (27.0%) were caregivers in 2018/19 and 2019/20, respectively. In 2018/19, 18 (14.6%) caregivers with influenza/ILI did not provide care while ill (42 [25.9%] in 2019/20).DiscussionIn Canadian older adults, influenza and ILI had notable impacts on ability to volunteer and provide care across two recent seasons. Optimization of influenza prevention in this population may yield important societal benefits.

Strategies to cut down drinking, alcohol consumption, and usual drinking frequency: Evidence from a British online market research survey

BackgroundRelatively little is known about how risky drinkers attempt to moderate their drinking in the absence of specialist support. The broader literature has identified multiple potential strategies that people use to cope with temptation when trying to control health-risk behaviours. This study aims to identify types of alcohol moderation strategies used by British adults, and to explore how concurrent alcohol consumption differs across moderation strategies, focusing on the important role of usual drinking frequency. MethodsWe use a continuous repeat cross-sectional survey and one-week drinking diary collected by the market research company Kantar; these provide detailed information on alcohol consumption during a diary week and on how individuals try to moderate alcohol use for 49,204 British adults trying to reduce their drinking from 2013 to 2019. We use Latent Class Analysis (LCA) to identify predominant types of moderation strategies. With a three-step method, we also analyse the associations between adopting different moderation strategies, measures of frequency and intensity of drinking events, and usual drinking frequency. ResultsWe found evidence of four alcohol moderation strategies: 29% of individuals use a pre-commitment-focused strategy (having fewer drinking occasions), two set of individuals adopt self-control strategies within drinking occasions (specifically 28% select smaller drinks and 5% have fewer drinks), while 38% adopt a mixed strategy that involves all three. Those using commitment tend to have a higher average consumption per drinking occasion but lower overall weekly consumption compared to those using self-control. Weekly alcohol consumption is particularly high among individuals who are usual everyday drinkers and use self-control to cut down drinking. ConclusionThis analysis provides a useful platform for further work, using prospective or intervention designs, to test the relative effectiveness of different moderation strategies for alcohol consumers who want to reduce their alcohol consumption.

Health behaviour change among UK adults during the pandemic: findings from the COVID-19 cancer attitudes and behaviours study

BackgroundCOVID-19 related lockdowns may have affected engagement in health behaviours among the UK adult population. This prospective observational study assessed socio-demographic patterning in attempts to change and maintain a range of health behaviours and changes between two time points during the pandemic.MethodsAdults aged 18 years and over (n = 4,978) were recruited using Dynata (an online market research platform) and the HealthWise Wales platform, supplemented through social media advertising. Online surveys were conducted in August/September 2020 when lockdown restrictions eased in the UK following the first major UK lockdown (survey phase 1) and in February/March 2021 during a further national lockdown (survey phase 2). Measures derived from the Cancer Awareness Measure included self-reported attempts to reduce alcohol consumption, increase fruit/vegetable consumption, increase physical activity, lose weight and reduce/stop smoking. Multivariable logistic regressions were used to assess individual health behaviour change attempts over time, adjusted for age, sex, ethnicity, employment and education.ResultsAround half of participants in survey phase 1 reported trying to increase physical activity (n = 2607, 52.4%), increase fruit/vegetables (n = 2445, 49.1%) and lose weight (n = 2413, 48.5%), with 19.0% (n = 948) trying to reduce alcohol consumption among people who drink. Among the 738 participants who smoked, 51.5% (n = 380) were trying to reduce and 27.4% (n = 202) to stop smoking completely. Most behaviour change attempts were more common among women, younger adults and minority ethnic group participants. Efforts to reduce smoking (aOR: 0.98, 95% CI: 0.82–1.17) and stop smoking (aOR: 0.98, 95% CI: 0.80–1.20) did not differ significantly in phase 2 compared to phase 1. Similarly, changes over time in attempts to improve other health behaviours were not statistically significant: physical activity (aOR: 1.07; 95% CI: 0.99–1.16); weight loss (aOR: 0.95; 95% CI: 0.90–1.00); fruit/vegetable intake (aOR: 0.98, 95% CI: 0.91–1.06) and alcohol use (aOR: 1.32, 95% CI: 0.92–1.91).ConclusionA substantial proportion of participants reported attempts to change health behaviours in the initial survey phase. However, the lack of change observed over time indicated that overall motivation to engage in healthy behaviours was sustained among the UK adult population, from a period shortly after the first lockdown toward the end of the second prolonged lockdown.

Educational attainment and willingness to use technology for health and to share health information – The reimagining healthcare survey

BackgroundAustralia has seen a rapid uptake of virtual care since the start of the COVID-19 pandemic. We aimed to describe the willingness of consumers to use digital technology for health and to share their health information; and explore differences by educational attainment and area of remoteness. MethodsWe conducted an online survey on consumer preferences for virtual modes of healthcare delivery between June and September 2021. Participants were recruited through the study’s partner organisations and an online market research company. Australian residents aged ≥18 years who provided study consent and completed the survey were included in the analysis. We reported the weighted percentages of participants who selected negative response to the questions to understand the size of the population that were unlikely to adopt virtual care. Age-adjusted Poisson regression models were used to estimate the prevalence ratios for selecting negative response associated with education and remoteness. ResultsOf the 1778 participants included, 29% were not aware of digital technologies for monitoring/supporting health, 22% did not have access to technologies to support their health, and 19% were not willing to use technologies for health. Over a fifth of participants (range: 21–34%) were not at all willing to use seven of the 15 proposed alternative methods of care. Between 21% and 36% of participants were not at all willing to share de-identified health information tracked in apps/devices with various not-for-profit organisations compared to 47% with private/for-profit health businesses. Higher proportions of participants selected negative response to the questions in the lower educational attainment groups than those with bachelor’s degree or above. No difference was observed between area of remoteness. ConclusionsImproving the digital health literacy of people, especially those with lower educational attainment, will be required for virtual care to become an equitable part of normal healthcare delivery in Australia.

Consumer behavior in an augmented reality environment: Exploring the effects of flow via augmented realism and technology fluidity

Advances in information technologies today have created rich forms of reality to engage consumers. This study examines the effects of augmented realism and technology fluidity of augmented reality (AR) applications on consumer decision-making. Aposttest-only between-group experiment was conducted in a laboratory setting to enable the completion of a simulated product-evaluation task via a web-based AR system, a mobile-app based AR system and a non-AR marketing device. Findings demonstrated that augmented realism and technology fluidity strongly influenced consumers’ flow experience, which led to cognitive and affective responses toward the brand and/or the AR-interface medium, in addition to increased purchase intention. The four sub-dimensions of flow also helped explicate the relationships between immersive shopping experience and cognitive, affective and behavioral outcomes. The study contributes to theory building in AR-based immersive and online marketing research.

Changes in social contacts in England during the COVID-19 pandemic between March 2020 and March 2021 as measured by the CoMix survey: A repeated cross-sectional study.

During the Coronavirus Disease 2019 (COVID-19) pandemic, the United Kingdom government imposed public health policies in England to reduce social contacts in hopes of curbing virus transmission. We conducted a repeated cross-sectional study to measure contact patterns weekly from March 2020 to March 2021 to estimate the impact of these policies, covering 3 national lockdowns interspersed by periods of less restrictive policies. The repeated cross-sectional survey data were collected using online surveys of representative samples of the UK population by age and gender. Survey participants were recruited by the online market research company Ipsos MORI through internet-based banner and social media ads and email campaigns. The participant data used for this analysis are restricted to those who reported living in England. We calculated the mean daily contacts reported using a (clustered) bootstrap and fitted a censored negative binomial model to estimate age-stratified contact matrices and estimate proportional changes to the basic reproduction number under controlled conditions using the change in contacts as a scaling factor. To put the findings in perspective, we discuss contact rates recorded throughout the year in terms of previously recorded rates from the POLYMOD study social contact study. The survey recorded 101,350 observations from 19,914 participants who reported 466,710 contacts over 53 weeks. We observed changes in social contact patterns in England over time and by participants' age, personal risk factors, and perception of risk. The mean reported contacts for adults 18 to 59 years old ranged between 2.39 (95% confidence interval [CI] 2.20 to 2.60) contacts and 4.93 (95% CI 4.65 to 5.19) contacts during the study period. The mean contacts for school-age children (5 to 17 years old) ranged from 3.07 (95% CI 2.89 to 3.27) to 15.11 (95% CI 13.87 to 16.41). This demonstrates a sustained decrease in social contacts compared to a mean of 11.08 (95% CI 10.54 to 11.57) contacts per participant in all age groups combined as measured by the POLYMOD social contact study in 2005 to 2006. Contacts measured during periods of lockdowns were lower than in periods of eased social restrictions. The use of face coverings outside the home has remained high since the government mandated use in some settings in July 2020. The main limitations of this analysis are the potential for selection bias, as participants are recruited through internet-based campaigns, and recall bias, in which participants may under- or overreport the number of contacts they have made. In this study, we observed that recorded contacts reduced dramatically compared to prepandemic levels (as measured in the POLYMOD study), with changes in reported contacts correlated with government interventions throughout the pandemic. Despite easing of restrictions in the summer of 2020, the mean number of reported contacts only returned to about half of that observed prepandemic at its highest recorded level. The CoMix survey provides a unique repeated cross-sectional data set for a full year in England, from the first day of the first lockdown, for use in statistical analyses and mathematical modelling of COVID-19 and other diseases.

Management of chronic low back pain and the impact on patients' personal and professional lives: Results from an international patient survey.

ObjectiveThe objective of this study was to investigate the impact of chronic low back pain (CLBP) on patients’ personal and professional lives, and management strategies applied to treat CLBP.MethodsA 60‐question survey was developed, and respondents from 16 countries with a self‐reported physician's diagnosis of CLBP were recruited via an online market research survey panel. Respondents were stratified as having mild, moderate, or severe pain. Target sample sizes per country and for pain severity were set. Data were weighted according to the known population and prevalence of CLBP in each country and the number of respondents from that country.ResultsResults from 9642 CLBP patients indicated that almost a quarter of patients with severe CLBP report a psychological comorbidity. Prescription pain medications were more commonly used by patients with severe CLBP (56%) than those with mild (20%) or moderate (34%) CLBP. Among those with severe CLBP who had been prescribed pain medication, 58% were prescribed opioids, with 1 in 4 patients using opioids for more than 5 years. Patients were primarily managed by general practitioners/primary care physicians, physiotherapists, neurologists, or orthopedic surgeons. CLBP negatively impacted patients’ daily activities, social lives, and work productivity.ConclusionChronic low back pain has pronounced effects on patients’ personal relationships, ability to work, and daily living. Almost 1 in four patients with severe CLBP reported a psychological comorbidity. Adherence to guidelines appears inconsistent, which is noteworthy as a substantial subgroup of patients with severe CLBP had been prescribed opioid medication for more than 5 years. Improved education is required to support healthcare professionals (HCPs) in identifying and understanding the complex biopsychosocial needs of CLBP patients to optimize pain management and to encourage referral of CLBP patients to physiotherapists and psychologists.

The Drawbacks of the Digital Transition of Marketing Research: Implications for Decision Makers and the Industry

The primary aim of this paper is to draw practitioners’ attention to lesser-known risks of digital marketing research: while it enables quick and low-cost results, quality and reliability are not guaranteed. The paper also surfaces broader consequences of transitioning from traditional research, based on offline investigations and face-to-face interviews carried out by professionals, to digital research. 
 
 The paper presents the results of a survey on a cohort of 200 freelance interviewers working for Italy’s main research institutions, conducted through a self-administered questionnaire. Recently online marketing research, especially through panels, has gained meaningful traction. As demand for traditional marketing research contracts, professional interviewers are experiencing a material drop in requests for their in-field services and a worsening working environment. In return, this affects the quality of on field research they can provide. This is the first study, to the best of the author’s knowledge, where issues and limitations of digital research are studied from the perspective of professional interviewers. 
 
 This study enables managers and organisations that commission marketing research to make more informed decisions when facing the trade-offs between traditional and digital methods. Furthermore, it provides a view on how such choices may impact the future of professional interviewers and their services.
 
  

How do internet memes affect brand image?

PurposeThis study aims to investigate how Internet memes affect brand image.Design/methodology/approachThe authors first used the Delphi method to refine Internet memes' constructs and dimensions and developed a scale for Internet memes. Second, the authors used a questionnaire to collect data from 348 valid Internet consumers.FindingsThe authors proposed four significant characteristics of Internet memes: humour, high positive emotional intensity, brand interactions and prestige, and high spreadability to prompt consumers to remake, share and spread memes. The study results indicate that Internet memes positively influence the brand image. However, not all meme characteristics were correlated with the brand image; only brand prestige, interaction and humour enhanced brand image.Originality/valueFor scholars in online marketing communication research, this study shifts the current paradigm of brand-generated and customer-passive to user-generated and customer-active. It also addresses the importance of pandemic effects of Internet memes on brand image. To be specific, this study presents the important symbolic values that Internet memes need to include to affect consumers' behaviour in response to perceived brand image by applying both mind infection and symbolic value perspectives. Finally, this study redefines the dimensions and measurements of Internet memes to address the lack of consensus and concrete scales regarding meme transmission characteristics and extending into online marketing communication strategies.Peer reviewThe peer review history for this article is available at: https://publons.com/publon/10.1108/OIR-11-2019-0364

The Need Recognition in Marketing of the Tailor-Made Furniture and Personalization Process of the Product through Design Management

Small business furniture manufacturers in the age of digital media are changing the concepts of marketing and sales based on the strategy they recognize the user experiences. This creates a difference between industrial furniture manufacturers and traditional carpentry companies that produce tailor-made furniture. For our research, we examine the core question: “How successfully do small kitchen furniture manufacturers face strong competition in the market through a product personalization approach, considering user experiences and by practicing design management strategy?” With the support of the on-line marketing research, we will research 120 experienced customers, study their marketing need and user experiences of kitchen furniture in the concept of design management strategy.

Use of Premedication Prior to Asparaginase (ASNase) Administration in Pediatric Acute Lymphoblastic Leukemia (ALL): Effect on Treatment Completion Rate

BackgroundIn pediatric patients with ALL, completion of ASNase treatment has been shown to improve survival (Silverman LB et al. Blood . 2001;97(5):1211-1218). Premedication has been used to reduce infusion and hypersensitivity reactions associated with ASNase therapy; however, premedication may mask the appearance of systemic hypersensitivity reactions, which may be associated with the development of neutralizing antibodies and reduced ASNase activity (Woods D et al. J Pediatr Oncol Nurs . 2017. doi:10.1177/1043454217713455). In the US, 2 formulations of asparaginase are available, a PEGylated form (PEG) of Escherichia coli- derived ASNaseand an immunologically distinct Erwinia chrysanthemi- derived form (ERW). Reported here are results of a physicians' survey conducted via market research to assess the effects of premedication on completion of ASNase treatment.MethodsAn online market research survey of US hematology/oncology physicians collected information on their treatment of pediatric ALL patients since the beginning of 2014. A patient chart audit was also included. Recruited physicians were required to have 2-35 years in practice, ≥75% of time in direct patient care with 80% compliance with treatment using Children's Oncology Group, Dana-Farber, St. Jude, or other pediatric ALL protocols. Patients (aged 1-21 years) were required to be personally managed by a physician, currently receiving or had received treatment for ALL. Physician practice setting affiliation (academic vs community), ASNase use, premedication (premed vs no-premed) use, ASNase-therapy interruption due to complications (physician-assessed hypersensitivity reaction [HSR] or other toxicity) and subsequent treatment decisions (PEG rechallenge, switch to ERW), and rates of therapy completion were also collected. Data collected were descriptive in nature and no inferential statistical tests were performed.ResultsEighty-five hematologists/oncologists (44% academic, 56% community) provided audited charts for 323 patients (median age, 14 years; 62% classified as high or very-high risk). For the 231 patients receiving PEG as initial ASNase therapy, premedication for the first and/or subsequent doses was used in 151 patients (65%). Premedications included antihistamines (60%), acetaminophen (59%), antiemetics (48%), and steroids (39%). Among the premed patients (n=151), 15 patients had ASNase treatment interrupted, 12 (80%) due to physician-assessed HSR. Among the no-premed patients (n=80), 13 patients had treatment interrupted, 10 (77%) due to physician-assessed HSR (Figure 1). These rates were higher than those for discontinuation due to toxicities other than HSR (3/15, 20% vs 3/13, 23%). For the premed patients with HSR, 5 were switched to ERW, and 7 were rechallenged with PEG. For the no-premed group, all 10 patients were switched to ERW. In patients with HSR, overall completion rates at time of audit were lower in the premed group (58%; 7/12) than in the no-premed group (100%; 10/10; 1 patient in each group was still on therapy at time of audit; Figure 2).ConclusionsIn this chart audit, the majority of pediatric ALL patients treated with PEG as initial ASNase therapy received premedication (65%). Hypersensitivity-like reaction was the most common physician-reported reason for ASNase treatment interruption, even in premedicated patients (80% of treatment interruptions). Patients without premedication had a higher rate of ASNase treatment completion than those who were premedicated. These results should be interpreted with caution given the retrospective nature of this chart audit, the subjective nature of HSR determination, and the small patient numbers.Support: Jazz Pharmaceuticals. [Display omitted] DisclosuresBernard:Jazz Pharmaceuticals: Employment. Rustay:Jazz Pharmaceuticals: Employment, Other: stock options. Mamedov:Jazz Pharmaceuticals: Employment, Other: stock options.

Social Media Big Data: The Good, The Bad, and the Ugly (Un)truths.

Social Media Big Data: The Good, The Bad, and the Ugly (Un)truths.