Oncocytic Schneiderian Papilloma Research Articles

Oncocytic Sinonasal Papilloma A Rare Case Report

Oncocytic sinonasal papilloma, also known as oncocytoma or oncocytic Schneiderian papilloma is a rare benign tumor that typically arises from the Schneiderian epithelium lining the nasal cavity and paranasal sinuses. There are three types of papillomas, of which oncocytic papillomas are the least common. It constitutes 3–5% of all the papilloma cases. Here we present a rare case report of a patient who was an 85-year-old female presented with shortness of breath and a slight obstruction in the nasal cavity, which she felt on the right side. She was examined clinically as sinonasal mass. A CT scan was performed, and surgical excision was suggested. After surgical removal tissue was sent for histopathological evaluation and a diagnosis of oncocytic papilloma was made.

Middle Ear Primary Oncocytic Schneiderian Papilloma: A Case Report.

Introduction:Chronic otitis media is a significant health problem, but middle ear and mastoid neoplasms, either benign or malignant, are extremely rare.Case Report:Here is a report from a 51-year-old female who presented persistent otorrhea with an aural polyp. The patient was operated on with the probable diagnosis of cholesteatoma. During surgery, a fragile mass was discovered, and histopathologic examination reported the diagnosis of a primary oncocytic Schneiderian papilloma. Microscopically it has pseudostratified epithelium of columnar cell epithelium with eosinophilic granular cytoplasm and hyperchromatic nuclei. The treatment of choice for Schneiderian papillomas is complete surgical removal.Conclusions:Although very rare, oncocytic Schneiderian papilloma should be considered a differential diagnosis of ear neoplasms such as auditory canal polyps.

Oncocytic schneiderian papilloma in maxillary sinus: report of one case and review of literature

目的 探讨鼻窦嗜酸细胞乳头状瘤的临床特点、影像学特征、病理学特点和治疗策略。 方法 回顾性分析北京清华长庚医院收治的1例右侧上颌窦嗜酸细胞乳头状瘤患者的临床资料，结合相关文献进行分析，讨论该疾病的临床特点、诊断和治疗。 结果 该患者无临床症状，CT检查为细条状高密度影，磁共振成像（MRI）检查提示T1WI高信号、T2WI低信号影。术前误诊为真菌性鼻窦炎，术中见上颌窦壁附着有暗红色乳头状新生物，完整切除肿瘤，术后病理示嗜酸细胞乳头状瘤。术后随访2年未见复发和癌变。 结论 鼻窦嗜酸细胞乳头状瘤临床症状和影像学检查常不典型，术前要综合分析避免误诊，术中要完整切除肿瘤。术后肿瘤容易复发和恶变，需定期随访。

Oncocytic Schneiderian Papilloma of the Maxilla; The report of a Case with evident malignant Foci

Oncocytic Schneiderian Papilloma of the Maxilla; The report of a Case with evident malignant Foci

Nasal oncocytic schneiderian papilloma: report of two cases

Nasal oncocytic schneiderian papilloma: report of two cases

Oncocytic Schneiderian papillomas: Clinical behavior and outcomes of the endoscopic endonasal approach in 33 cases

The purpose of this study was to evaluate the clinical behavior of oncocytic Schneiderian papillomas in relation to the rate of malignant transformation and recurrences and to report the long-term results of the endoscopic endonasal treatment. A retrospective analysis was carried out on patients with oncocytic papilloma, endoscopically managed over the past 20 years, at 2 university centers following a uniform policy. Thirty-three patients were treated between November 1991 and December 2010. The mean follow-up period was 62 months. We observed 2 cases of persistence (6%) at the maxillary sinus level. Both of these patients underwent endoscopic surgical revision. Squamous cell carcinoma (SCC) was observed in 1 patient (3%). The endonasal endoscopic technique proved to be a safe and effective approach for the treatment of oncocytic papillomas. An oncocytic papilloma is not to be considered a negative prognostic factor in terms of malignant transformation or recurrence.

ONCOCYTIC SCHNEIDERIAN PAPILLOMA OF FRONTAL SINUS

Oncocytic Schneiderian papilloma (OSP) is one of the three morphologically distinct tumors that arise from Schneiderian membrane (the others include exophytic papilloma and inverted papilloma). OSP almost always occurs unilaterally in the paranasal sinuses, usually in the maxillary sinus, ethmoid cells or sphenoid sinus. We report a case of a 64-year-old woman with OSP arising from the left frontal sinus. In the report herein, we describe an OSP originating in the region of frontal sinus, which, to the best of our knowledge, represents the first documented example in English literature of OSP developing in this anatomical site.

Nasal papilloma: A comparison between inverted papilloma and oncocytic schneiderian papilloma

The Schneiderian membrane gives rise to 3 morphologically distinct tumours: septal, inverted (IP) and oncocytic schneiderian papillomas (OSP). OSP, although, almost parallel to IP, still have its own distinct features in the incidence, location, clinical presentation and histological examination. Despite the differences, the standard treatment is still surgical removal of the tumour. External approach is preferred but in view of advanced endoscopic technique, it is feasible to remove the tumour endoscopically with carefully selected tumour presentation. DOI: http://dx.doi.org/10.3329/bjo.v18i2.12033 Bangladesh J Otorhinolaryngol 2012; 18(2): 215-218

Cylindrical Cell Papilloma (Oncocytic Schneiderian Papilloma): Clinicopathological Study of Five Cases.

To study the clinicopathological findings of cylindrical cell papilloma (oncocytic schneiderian papilloma) diagnosed among patients at Bahrain Defense Force Hospital with review of literature. All cases of cylindrical cell papilloma were retrieved from the pathology register from 2006-2010. The medical records of the cases were studied for age, sex, clinical presentation, and imaging reports along with the histopathological findings. Five cases were found and showed male to female ratio 4:1. Their ages were between 36-71 years with average age of 55 years. The main symptom found was unilateral nasal obstruction mainly involving the left side. All papillomas were removed by endoscopic sinus surgery. Four patients had regular followup with complete recovery, while only one case was lost for followup. Cylindrical cell papilloma is a variant of sinonasal schneiderian papilloma. Although most are benign complete excision is the treatment of choice to prevent tumour recurrence as a proportion exhibit unpredictable biological behavior. This study is an important reminder for both clinicians and pathologists to recognize this tumor and to differentiate it from other tumours and rhinosporidiosis. Regular followup is an important strategy for complete recovery and tumour-free surveillance.

Oncocytic Schneiderian Papilloma Presenting as an Intensely Hypermetabolic Lesion of the Maxillary Sinus on18F-Fluorodeoxyglucose Positron Emission Tomography/CT: A Case Report and Literature Review

Oncocytic Schneiderian Papilloma Presenting as an Intensely Hypermetabolic Lesion of the Maxillary Sinus on¹⁸F-Fluorodeoxyglucose Positron Emission Tomography/CT: A Case Report and Literature Review

Oncocytic schneiderian papilloma of the nasal cavity and maxillary sinus: a case report

患者女，42岁，因间断性右侧鼻塞、流涕2年，加重伴鼻部肿痛2个月于2009年3月入院。患者2年前无明显诱因出现右侧鼻塞、流涕，鼻涕呈黄白色，略黏稠，无鼻出血、耳鸣等症状。1年前曾在当地医院行鼻内镜下右侧鼻腔“内翻性乳头状瘤”手术，术后鼻腔通气良好。6个月前再次出现右侧鼻塞、流涕，近2个月症状明显加重，并伴鼻部肿痛。专科检查：右侧总鼻道内见脓性分泌物，中鼻道可见半透明荔枝肉状新生物，粉红色，触之易出血，左侧鼻腔未见异常。

A rare case of oncocytic Schneiderian papilloma with intradural and intraorbital extension with notes of operative techniques

Epithelial cells of cylindrical cell papilloma are oncocytes, which arise from the sinonasal respiratory epithelium, hence the term Oncocytic Schneiderian papilloma.This is a rare and benign neoplasm of the nose and paranasal sinuses and it should be considered in the work-up of all unilateral nasal polypoid lesions. Clinically behaviour is comparable to inverted papillomas for local recurrence and malignancy coexistence. We report a case arisen from the nasoethmoidal space that extended to the anterior skull base through a bone dehiscence with intradural invasion and orbital space involvement. Surgical therapy is the treatment of choice, the endonasal endoscopic approach can be used in most of the cases and this surgical technique is safe and suitable also in presence of an extra nasal extension. We describe our experience for management of this kind of lesions and some notes on our operative technique.

Oncocytic Schneiderian Papilloma Confined to the Maxillary Sinus and Detected by FDG-PET

Oncocytic Schneiderian Papilloma Confined to the Maxillary Sinus and Detected by FDG-PET

High Uptake in Schneiderian Papillomas of the Maxillary Sinus on Positron-Emission Tomography Using Fluorodeoxyglucose

Schneiderian papillomas are benign tumors of the nasal cavity and paranasal sinuses often asymptomatic in their early stages. We report a case of a maxillary sinus oncocytic schneiderian papilloma first detected by positron-emission tomography by using fluorodeoxyglucose (FDG). Schneiderian papillomas demonstrate increased FDG uptake, similar to that of other oncocytic tumors, making it important for otolaryngologists and radiologists to realize that high uptake of FDG does not necessarily indicate a malignant lesion.

Oncocytic schneiderian papilloma occurring in a young Nigerian male: A case report

Oncocytic Schneiderian papilloma is one of the three morphologically separate tumors that arise from the Schneiderian membrane (the others are fungi form papilloma and inverted papilloma). It is quite rare in our environment. We report a case of Oncocytic Schneiderian papilloma arising from the right maxillary sinus and extending to the ipsilateral nasal region in a 26year old Nigerian male. The growth was present for a period of 5 months before his presentation on 18-10-2005 and recurred again nine months later after excision. Both excised tissues were confirmed by histology to be Oncocytic Schneiderian papilloma, with no evidence of malignancy after a rigorous search.

Malignancies arising in oncocytic schneiderian papillomas: A report of 2 cases and review of the literature

c Oncocytic schneiderian papillomas (OSPs) are uncommon benign neoplasms that arise from the sinonasal schneiderian epithelium. Malignancies arising in OSPs are rare, and, to our knowledge, only 14 such instances have been reported in the medical literature. We report 2 additional cases—a small cell carcinoma and a sinonasal undifferentiated carcinoma arising in OSPs and presenting synchronously with the benign neoplasm. The potential for malignant transformation in OSPs is small, but warrants that these papillomas be completely excised to exclude a coexisting carcinoma. (Arch Pathol Lab Med. 2001;125:1365‐1367)

Carcinoma ex oncocytic Schneiderian (cylindrical cell) papilloma

Introduction: This study reviews the clinicopathologic features of carcinoma presenting in oncocytic Schneiderian papilloma (OSP; cylindrical cell papilloma), a rare histologically distinctive papilloma sharing features with inverted papilloma. Materials and Methods: Nine cases of carcinoma ex OSP (1970–1990), six from the files of the Armed Forces Institute of Pathology (Washington, DC) and three from the surgical pathology files, Presbyterian-University Hospital and Eye and Ear Institute (Pittsburgh, PA), were studied. One case was previously reported. Clinical data were obtained from the patients' medical records. All available histologic slides were reviewed. Results: The patients (eight men, one woman) ranged in age from 48 to 83 years (mean age, 74 years). The carcinoma and OSP were synchronous in eight patients. In one case, the carcinoma occurred 8 years after OSP was diagnosed on biopsy. The presenting manifestations included nasal obstruction, “polyps,” epistaxis, and proptosis. Radio-graphically, a sinonasal mass was present, often with extension to adjacent sites and bone destruction. Most patients received postoperative irradiation. Of six patients with follow-up, four died of carcinoma and two were alive without disease at 1.5 and 7 years, respectively. The types of carcinoma were: squamous cell (n = 6), high-grade mucoepidermoid (n = 2), and sinonasal undifferentiated (n = 1). Histologic transition was observed between carcinoma and dysplastic/benign OSP in eight cases. Conclusion: Demonstration of histologic continuity between carcinoma and dysplastic OSP epithelium in eight of our nine cases indicates origin of carcinoma from the OSP, rather than a coincidence of the two neoplasms. Although histologically benign, OSP should be totally excised at diagnosis because of a potential for malignant transformation.

Carcinoma Arising in Oncocytic Schneiderian Papilloma

Two men aged 54 and 73 years, respectively, had oncocytic Schneiderian papilloma (OSP) containing synchronous carcinoma at the time of first biopsy. In both cases, invasive carcinoma involved a small proportion of excised tissue and was in continuity with dysplastic surface epithelium. Our cases document that the epithelial component of OSP can undergo malignant transformation. The focal involvement of OSP with carcinoma underscores the need to examine all excised tissue microscopically.

Oncocytic Schneiderian Papilloma in a Young Adult: A Rare Diagnosis

The oncocytic Schneiderian papilloma (OSP) is a rare neoplasm of the nose and paranasal sinuses. The majority of the approximately twenty patients reported in the literature with this papilloma have been over the age of fifty at the time of diagnosis. The 33-year-old woman reported here is the youngest patient with this lesion to date. The OSP should be considered in the work-up of all unilateral nasal polypoid lesions. This lesion's propensity for recurrence and its documented association with synchronous malignant disease warrant surgical excision by en bloc resection of the lateral nasal wall, with corresponding careful microscopic evaluation of all excised tissue.

Oncocytic schneiderian papilloma: A reappraisal of cylindrical cell papilloma of the sinonasal tract

Cylindrical cell papilloma (CCP) is the rarest of three morphologically distinct papillomas that occur in the nose and paranasal sinuses. Because it is unfamiliar to many pathologists, it is often mistaken histologically for papillary adenocarcinoma or even rhinosporidiosis. The clinical and pathologic features of six new cases are reported and compared with those of 14 others reported in the literature. The results of the light microscopic, histochemical, immunocytochemical (cytochrome c oxidase), and ultrastructural studies described here provide conclusive evidence that the swollen, granular, eosinophilic epithelial cells that compose CCP are true oncocytes that arise primarily, or perhaps exclusively, from the respiratory (Schneiderian) epithelium of the sinonasal passages rather than from minor salivary glands. Continued designation of the CCP as such should therefore be discouraged in favor of a more precise term reflecting this derivation. The phrase "oncocytic Schneiderian papilloma" is proposed.