District Saharanpur is a rich source of medicinal plants because of its physical features, the north and the north-east of the district is surrounded by Shivalik hills and having rich biodiversity. The objective of present study was to investigate the presence of phytochemicals in five medicinal plants such as, Tinospora cordifolia (Thunb.)Miers, Bryophyllum pinnatum (Lam.)Oken , Terminalia belerica Roxb., Xanthium strumarium Linn. and Oldenlandia corymbosa Linn. For the study the solvents used were water, methanol, ethanol and acetone. Soxhlet apparatus was used for the organic solvent extraction. Carbohydrates, proteins, flavonoids, tannins, saponin, and phenols were detected in these selected medicinal plants. Our analysis proved that crude aqueous and organic solvent extracts of these plants having the bioactive compounds which are medicinally important for the use in the treatment of various diseases