Odss Ratio Research Articles

Predictors of In-hospital Death in Patients with Stanford Type B Acute Aortic Dissection

Background: Even with immediate surgical intervention, acute aortic dissection (AAD) is a cardiovascular emergency with a high mortality rate. The purpose of this study was to look at the relationship between in-hospital mortality and red cell distribution width (RDW)/lymphocyte ratio (RLR), monocyte/lymphocyte ratio (MLR), and systemic immune inflammation index (SII) in patients with type B acute aortic dissection (BAAD).
 Materials and methods: 59 BAAD patients who presented to the emergency room of a tertiary hospital were included in this cross-sectional study. The predictive ability and cut-off value of biomarkers for mortality were evaluated using Receiver Operating Characteristic (ROC) analysis. The variables believed to be connected to in-hospital mortality were subjected to multiple regression analysis, and the odds ratio was calculated.
 Results: The study consisted of 59 patients in total, 44 of whom (74.6%) were male. 17 of these patients died in the hospital. In terms of predicting in-hospital mortality in BAAD patients, MLR, and neutrophil/lymphocyte ratio (NLR) have excellent diagnostic power (AUC: 0.826, 0.822, respectively), while platelet/lymphocyte ratio (PLR), RLR, and SII have acceptable diagnostic power (AUC: 0.758-0.786). Increased NLR, PLR, MLR, RLR, and SII were found to be independent predictors of in-hospital mortality in patients with BAAD (odss ratio: 9.16, 7.68, 9.33, 6, 8.57, respectively).
 Conclusion: MLR, RLR, and SII are valuable parameters for estimating in-hospital mortality in adult BAAD patients. Increased NLR, PLR, MLR, RLR, and SII in BAAD patients are independent predictors of in-hospital mortality.

DETERMINAN KEJADIAN KISTA OVARIUM PADA WANITA USIA SUBUR DI KABUPATEN BALANGAN MENGGUNAKAN REGRESI LOGISTIK BINER

Ovarian cysts are the most common gynecologic cases of many gynecologic cancers. Ovarian cyst is a disease that causes many deaths. This high mortality rate is due to the fact that the disease is initially asymptomatic and only causes complaints when metastases have occurred so that 60-70% of patients come at an advanced stage. Based on the results of the 2007 Basic Health Research survey, the number of patients with ovarian cysts in South Kalimantan was 1,2% of 56 respondents. This study took a case study in a district in South Kalimantan, namely Balangan Regency with the aim of explaining the characteristics of the distribution of ovarian cysts and the factors that influence the incidence of ovarian cysts in women of childbearing age in Balangan Regency using binary logistic regression method. Based on descriptive statistical analysis, it was found that the distribution characteristics of ovarian cyst sufferers were from 59 people who had checked for cyst symptoms at Balangan Hospital, 46 people were known to have cysts, while 13 people were not known to have cysts. Based on binary logistic regression analysis, the factors that influence the incidence of ovarian cysts for data on the incidence of ovarian cysts in Balangan Hospital are parity and employment status, while the age factor has no significant effect. Using the Odss Ratio (OR) parity value, patients with nulliparous status had a 0,033 higher risk of developing ovarian cysts than patients with multiparous status. using the OR value of the occupational status patients who had a job had a 0,014 higher risk of developing ovarian cysts than patients who did not have a job. Keywords: Ovarian cysts, Logistic binary, Odds Ratio.

The patterns of active commuting to school change along the school-life in spanish youth

This study describes rates of active commuting to school (ACS) among Spanish school students and examines differences in ACS between different and consecutive educational levels, educational stages and school grades, within the Spanish educational system. Data were obtained from 28 cross-sectional studies conducted across Spain in 2010-2017. The analytical sample comprised 42,074 participants; namely, 5,327 children aged 3-5.99 years old (48% girls), 18,329 children aged 6-11.99 years old (50% girls) and 18,438 adolescents aged 12-18 years old (49% girls). Compared to pre-primary education, those in primary education (Odss ratio (OR)= 1.29, p < 0.01), compulsory secondary education (OR= 1.36, p < 0.01) and upper secondary education (OR= 1.38, p < 0.01) had higher odds of ACS. Additionally, compared to primary education, those in compulsory secondary education had higher odds of ACS (OR= 1.05, p < 0.01). Adolescents attending 1° grade of compulsory secondary education had higher odds of ACS than their counterparts attending to 6° grade of primary education (OR= 1.16, p < 0.05); no other associations between consecutive school grades within and between educational stages were found (all, p > 0.05). This study suggests significant shifts in ACS over the transition from pre-primary education to primary education and from primary education to compulsory secondary education. Educational and policy strategies are important to continue promoting active travel behaviors to school since the first educational stage in youth people.

Identification of risk factors for ileus after orthopedic surgery: A comparative study

Aim: To examine the risk factors for Post operative ileus encountered after orthopedic surgery.&#x0D; Material and Methods: A total of 53 patients who were operated on by the orthopedics clinics who were consulted to the general surgery department during the postoperative period. Considering the etiology of the consultation, the patients were divided into 2 groups as ileus (n: 34) and non-ileus (n: 19).&#x0D; Results: The median age of the patients in the ileus group was 75.5 (26-95). While hypertension (HT) was the most common comorbid disease in patients in the ileus group, (p=.001). While combined anesthesia was frequently preferred in the ileus group, (p=.022). Lower extremity surgeries were performed more frequently in the ileus group (p=.007). The length of hospital stay was found to be higher in the ileus group, (p=.040). In terms of complications according to the clavien dindo classification, grade 3b was more common in the ileus group, (p=.039). As a result of the binary regression analysis performed to determine the risk factors for ileus; age (odss ratio (OR) ) = 1.034,; 95% CI (1.004-1.065); p=.027), day 5 consultation ( (OR) = 0.073; 95% CI (0.014-0.368); p=.002), and HT ( (OR) = 7.042; 95% CI (2.017-24.589); p=.002).&#x0D; Conclusion: Patients with geriatric and HT should also be prepared for ileus if lower extremity surgery is to be performed.

Health-related quality of life according to the presence of insulin resistance in ten years follow-up

Abstract Background Insulin resistance is the primary cause of metabolic syndrome, which in turn reflects a real variety of risk factors, closely linked to each other. Thus, we aimed to investigate health-related quality of life scores according to the presence of insulin resistance among citizens of Palanga in Lithuania, in the survey in 2003 and 2013. Methods A randomized epidemiological study was performed out for 835 subjects. All study participants were evaluated according to for socio-demographic characteristics, behavioral factors, health-related quality of life and self-perceived health using questionnaires. Fasting blood samples were draw from all participants for biochemical tests for the glucose and insulin. Insulin resistance was evaluated by the homeostasis model assessment of insulin resistance. Results All study participants were stratified into groups without and with insulin resistance in the survey in 2003 and 2013 years follow up. Participants with insulin resistance were more likely to be male, with higher body mass index, had lower than higher education, and with moderate self-related health. In subjects with insulin resistance, after adjusting with various factors, logistic regression analysis showed, that within 10 years, a significantly higher chance of deteriorating health-related quality of life in the areas of: physical functioning (odss ratio [OR] = 1.15, p &amp;lt; 0.001), emotional role limitations (OR = 1.07, p = 0.034), social functioning (OR = 1.26, p = 0.004), pain (OR = 1.09, p = 0.005) and general health perception (OR = 1.07, p = 0.022). Conclusions People with insulin resistance are significantly more likely to have a deterioration in their health-related quality of life in the areas of physical functioning, emotional role limitations, social functioning, pain and general health perception after 10 years period. Key messages Over the course of ten years, significant changes were observed in domains of physical functioning, social functioning and general health perception in subjects with insulin resistance. Results of this study provide evidence that individuals with insulin resistance have a significantly higher chance of deteriorating health-related quality of life within 10 years.

Hyperbilirubinemia as an Indicator of Perforated Acute Appendicitis in Pediatric Population: A Prospective Study.

Background: This prospective cohort study aimed to investigate the association of hyperbilirubinemia with perforated appendicitis in the pediatric population. Patients and Methods: A total of 284 children in whom the diagnosis of acute appendicitis was established were included in this study. The patients were allocated in study groups in regard to operative findings. The first study group included patients who had perforated appendicitis (n = 64; 22.5%) whereas the patients in the second group had simple appendicitis (n = 220; 77.5%). Blood samples for serum bilirubin levels and acute inflammatory markers were taken before the patients underwent surgery. The primary outcome of the study was to investigate whether the level of serum bilirubin should be used to distinguish between simple and perforated appendicitis. Results: The median level of serum bilirubin in children with perforated appendicitis was 27 mcmol/L whereas the patients with simple appendicitis had lower median levels of serum bilirubin (10 μmol/L; p < 0.001). An area under the receiver operating characteristic (ROC) curve for total serum bilirubin was 0.876 (95% confidence interval [CI], 0.820-0.929) in the patients who had a perforated appendicitis. An ROC analysis showed the best sensitivity (92%) and specificity (77.3%) for a cutoff value of 15.5 mcmol/L for total serum bilirubin (p < 0.001). Hyperbilirubinemia at admission was found in 35 patients (54.7%) with complicated appendicitis and in 14 patients (6.4%) with non-perforated appendicitis (p < 0.001). The modeling of collected data by multivariable logistic regression identified serum bilirubin concentration (odss ratio [OR] = 1.12; 95% CI, 1.07-1.18; p < 0.001), serum sodium concentration (OR = 0.64; 95% CI, 0.51-0.81; p < 0.001), body temperature (OR = 2.48; 95% CI, 1.05-0.84; p < 0.001), and duration of symptoms (OR = 1.06; 95% CI, 1.02-1.09; p < 0.001) as risk factors for perforated appendicitis. Conclusion: Elevateds level of total serum bilirubin may be useful as an indicator of perforated appendicitis in children. Levels of bilirubin in serum is an inexpensive, simple, and available laboratory marker and should therefore be recommended in the initial evaluation for acute appendicitis in pediatric patients.

Association of Thrombin-Activatable Fibrinolysis Inhibitor with Acute Pulmonary Embolism.

Thrombin-activatable fibrinolysis inhibitor (TAFI) inhibits fibrinolysis and high levels may have an association with thrombosis. The aim of the current study was to investigate the association of TAFI antigen levels with pulmonary thromboembolism (PTE). A case-control study was conducted with 29 patients with PTE and 17 age- and gender-matched control individuals. Plasma levels of TAFI were measured at the time of diagnosis, then at 3 and 6 months after the event. Initial TAFI levels (%) were higher in patients with PTE than in the control group (190,0 [65,0-250,0] vs 133,0 [83,0-153,0]; p = 0.003). TAFI levels significantly decreased at the third and sixth months after initial diagnosis (p < 0.05). The percentage reductions in TAFI levels were 12 and 36.8% at 3 and 6 months, respectively. The Odss ratio (OR) of TAFI level for PTE was found to be 1.024 (95% CI: 1.007-1.040; p = 0.005). There was no significant correlation of initial TAFI levels with age, gender, smoking status, history of thrombosis, pulmonary artery pressure, and D-dimer levels (p > 0.05). In the sixth month of treatment, patients with residual thrombosis were seen to have similar baseline levels and reductions of TAFI as patients without residual thrombosis (p > 0.05). The result of this study suggests that high TAFI levels may have a role in the occurrence of PTE without impact on treatment outcome.

Relationship between CHA2DS2-VASC score on admission to emergency department and in-hospital major adverse cardiovascular events in patients diagnosed with ST-elevation myocardial infarction

Abstract Funding Acknowledgements Type of funding sources: None. Inotroduction . CHA₂DS₂-VASc scoring system, which includes traditional risk factors of coronary artery disease, is actually created to determine the risk of thromboembolism in patients with atrial fibrillation. In this study; the value of CHA₂DS₂-VASc score, which can be calculated easily on admission, was evaluated for predicting in-hospital adverse outcomes in ST elevation miyocardial infarction (STEMI) patients without atrial fibrillation. Method This was a single center cross-sectional study. 1933 STEMI patients enrolled to the study. Primary end points include in-hospital death, cardiopulmonary arrest and cerebrovascular accident and were identified as MACE Results MACE rate was 10% (193 patients), in-hospital mortality rate was 9% (169 patients).In proportional logistic regression analysis, CHA₂DS₂-VASc score was an independent predictor for MACE (OR and CI 95%, 2.31[1.37-3.90]; p value:0.0016). In the regression analysis, the CHA₂DS₂-VASc score was taken as an uncatagorized continuous variable, and the relationship between the CHA₂DS₂-VASc score and MACE was observed to be linear. Additionally heart rate (OR and 95% CI, 1.56 [0.97- 2.50]; p value: 0.0242), killip class on admission (OR and 95% CI, 24.19[10.74-54.46]; p value &amp;lt;0.0001), creatinine level on admission (OR and 95% CI, 1.54 [1.10-2.16]; p value: 0.0024), peak CK-MB level (OR and 95% GA, 1.63 [0.98-2.70]; p value: 0.0001) and presence of no-reflow (OR and 95% CI, 2.45 [1.25-4.80]; p value: 0.0085) were indendified as other independent predictors of MACE. Conclusion CHA₂DS₂-VASc score was observed as an indepented predictor for MACE in STEMI patients. To evaluate the relationship between CHA₂DS₂-VASc score and outcomes, the linear analysis of the CHA₂DS₂-VASc score without categorization in prediction model is used and this is the main difference of our study from others. Table-1 Variables Odss Ratio (OR) and 95% CI p value CHA₂DS₂-VASc ( 0 to 3) 2.31 (1.37-3.90) p = 0,0016 Heart Rate (Beats per minute) ( 68 to 94) 1.56 (0.97-2.50) p =0.0242 Systolic Blood Pressure (mmHg) ( 115 to 156) 0.83 (0.51-1.34) p = 0.3523 Killip Class ( I to IV) 24.19 (10.74-54.46) p &amp;lt; 0.0001 Hemoglobin (g/dL) ( 12 to 15) 0.96 (0.54-1.70) p = 0.4066 Creatinine ( mg/dL) (0.74 to 1.0) 1.54 (1.10-2.16) p = 0.0024 Peak CK-MB (IU/L) (40.8 to 165.1) 1.63 (0.98-2.70) p = 0.0001 No-reflow (yes) 2.45 (1.25-4.80) p = 0.0085 Independent predictors of MACE in STEMI patients according to penalized proportional odds logistic regression analysis Abstract Figure. Partial impact plots of predictors

Metabolic syndrome and masticatory hypofunction: a cross-sectional study

The objective of this paper is to clarify the rate of abdominal obesity (AO), waist-to-height ratio (WHtR), metabolic syndrome (MetS) and determine the relationship with the masticatory capacity (MC) in terms of total functional tooth units (t-FTU) in a representative sample of older Spanish adults. This cross-sectional study included 544 adult subjects aged 50 or over, who were prospectively selected and who had participated in a survey conducted in a primary dental care service in a Public Oral Health Service in Spain. Anthropometric, clinical variables and t-FTUs were obtained through a calibrated and well-established protocol. Univariate and multivariate binary and multinomial logistic regression analyses were developed. With regards to the t-FTU or MC, it was poor in 60.3%, good in 17.6%, and complete in 22.1% of the sample. The univariate odss ratio (OR) for MetS and AO increased as the MC decreased and as the age group increased. With regards to gender, women presented with an OR of 5.56 (CI 95% 3.70-8.38). With regards to the WHtR-a3 (WHtR grouped into three categories), the univariate ORs were all significant for morbid obesity compared to the healthy group, with a risk of 6.86 (CI 95% 3.23-14.58) for patients with poor MC compared to those with complete MC. Masticatory hypofunctionality could be associated with the presence of MetS. Clinical relevance: The number of t-FTUs is directly related to AO.

RISK FACTORS OF TYPE 2 DIABETES MELLITUS DURATION AND NON-COMPLIANCE WITH MEDICATION TO POOR GLYCEMIC STATUS

Background: Type 2 diabetes mellitus is a chronic disease that is still a global health problem. Uncontrolled diabetes mellitus (DM) can result in poor glycemic status, with factors that affect patients including long-term DM and medication compliance. Purpose: This study aimed to determine the risk factors of long-term DM and non-compliance with medication on the poor glycemic control status of patients with type 2 DM. Methods: This type of research used observational analysis with a case–control design. Samples were taken from patients with type 2 DM, with 40 cases and 40 controls. The criteria for sample inclusion were that the patients had a glycosylated hemoglobin level check, were willing to be research respondents, and could communicate well. The exclusion criterion was patients experiencing a drastic decline in health status during the study. The sampling technique used was consecutive sampling. This research was conducted at the Panti Wilasa Citarum Hospital in Semarang City from July to September 2019. The relationship and the risk of long-term DM and adherence to taking medication with glycemic status were tested using the chi-square test. Results: This study showed that a duration of DM &gt;5 years (p = 0.01; Odss Ratio (OR) = 3.46; 95% confidence interval [CI] = 1.37 &lt; OR &lt; 8.69) and non-compliance with taking medication (p = 0.02; OR = 3.15; 95% CI = 1.25 &lt; OR &lt; 7.93) are risk factors for poor glycemic status. Conclusion: Duration of DM &gt;5 years and non-compliance with taking medication are risk factors for poor glycemic status in patients with type 2 DM.

Analisis Penggunaan Gadget Terhadap Pola Komunikasi Keluarga

Indonesia merupakan negara yang menempati urutan kedua didunia dalam penggunaan gadget. Semakin meningkatnya jumlah pengguna gadget di era modern ini, banyak menyebabkan efek negatif bagi manusia, dimana salah satunya yakni menurunnya pola komunikasi efektif antara anak remaja dengan orang tua. Tujuan penelitian ini yaitu untuk mengetahui hubungan antara penggunaan gadget terhadap pola komunikasi dengan keluarga pada siswa-siswi kelas x di SMK Yabhinka Kota Cilegon. Desain penelitian cross sectional, penelitian dilakukan pada bulan juni 2018, dan responden 77 orang. Hasil penelitian menunjukan bahwa dari 45 responden dengan penggunaan gadget sering terdapat 44 orang (97,8%) yang pola komunikasi dengan keluarganya kurang baik dan 1 (2,2%) yang pola komunikasi dengan keluarganya baik. 32 responden dengan penggunaan gadget kadang-kadang terdapat 5 orang (15,6%) yang pola komunikasi dengan keluarganya kurang baik dan 27 orang (84,4%) yang pola komunikasi dengan keluarganya baik. Berdasarkan hasil uji chi square menunjukan bahwa nilai p = 0,000 (&lt; 0,05) dan nilai OR (Odss Ratio) 237. Kesimpulannya adanya hubungan antara penggunaan gadget terhadap pola komunikasi dengan keluarga karena ditemukan banyaknya responden yang menyalahgunakan gadget, yakni kecanduan gadget (bermain game disaat jam pelajaran berlangsung), mempunyai jiwa individual, minimnya komunikasi yang efektif, dan interaksi yang serba membutuhkan gadget sebagai medianya

Association between polymorphisms in CXCR2 gene and preeclampsia.

BackgroundPreeclampsia is a serious pregnancy‐specific syndrome with incompletely understood pathogenesis. Previous study has demonstrated that the decreased CXCR2 in preeclamptic placentas may contribute to the development of preeclampsia. The role of single nucleotide polymorphisms (SNPs) of CXCR2 gene in the pathogenesis of preeclampsia remains largely unexplored. Thus, we aimed to investigate the association between polymorphisms of CXCR2 gene and preeclampsia in Han Chinese women.MethodsTotally 481 pregnant women, including 243 controls and 238 patients with preeclampsia were recruited. The rs1126579 and rs2230054 polymorphisms in CXCR2 gene were tested using polymerase chain reaction‐restriction fragment length polymorphism method.ResultsSignificantly increased risk of preeclampsia was observed in the rs1126579 CC or TC/CC genotypes when compared with TT genotype (CC vs. TT: odss ratio [OR] = 2.11, 95% confidence interval [CI] = 1.18–3.76, p = 0.039; TC/CC vs. TT: OR = 1.89, 95% CI = 1.29–2.78, p = 0.001). Markedly higher risk of preeclampsia was found to be associated with rs1126579 TC genotype (TC vs. TT/CC: OR = 1.48, 95% CI = 1.04–2.12, p = 0.031). After stratification analysis, the different distribution of TC/CC genotypes was particularly significant in the severe preeclampsia group (OR = 2.15, 95% CI = 1.42–3.24, p < 0.01), the early‐onset severe preeclampsia group (OR = 1.97, 95% CI = 1.14–3.42, p = 0.013), and the late‐onset severe preeclampsia group (OR = 2.29, 95% CI = 1.39–3.78, p < 0.01). Besides, TC genotype carriers had a 1.55 fold increased risk of severe preeclampsia (95% CI = 1.06–2.27, p = 0.022) and a 1.80 fold increased risk of late onset severe preeclampsia (95% CI = 1.14–2.83, p = 0.01) than those of TT/CC genotype carriers.ConclusionsOur study suggests a genetic association between rs1126579 polymorphism in CXCR2 gene and increased risk of preeclampsia. These data provide a new clue for future investigation.

Are exposures to ready-to-eat food environments associated with type 2 diabetes? A cross-sectional study of 347 551 UK Biobank adult participants

Rapid urbanisation and associated socioeconomic transformations have modified current lifestyles, shifting dietary preferences towards ready-to-eat, calorie-dense food of poor nutritional quality. The effect of ready-to-eat food environments that sell food for instant consumption on the risk of type 2 diabetes has received scant attention. We therefore aimed to examine the association between exposure to ready-to-eat food environments and type 2 diabetes in a large and diverse population sample. We conducted a cross-sectional study of adult male and female participants from the baseline phase of the UK Biobank cohort. Participants in this cohort were aged 37-73 years and resided in one of 21 cities in the UK. Ready-to-eat food environments, which we determined from a modelled and linked built environment database, were objectively measured within 1-km catchment areas of the residential streets of participants and were expressed as metrics of density and proximity to the participants' homes. We used logistic regression models to examine the associations between exposure to ready-to-eat food environments and the odds of type 2 diabetes, adjusting for individual covariates such as physical activity. As sensitivity analyses, we investigated the associations between the street distance to the nearest ready-to-eat food outlet and type 2 diabetes. We also tested post hoc for effect modification by sex, income, body-mass index, and location of the UK Biobank collection centre. Of 502 635 UK Biobank participants enrolled between March 13, 2006, and Oct 1, 2010, the sample analysed included 347 551 (69·1%) participants. The density of ready-to-eat food environments within a 1-km catchment area was associated with higher odds of type 2 diabetes for participants in the groups with highest exposure to restaurants and cafeterias (odss ratio 1·129, 95% CI 1·05-1·21; p=0·0007) and a composite measure of ready-to-eat outlet density (1·112, 1·02-1·21; p=0·0134) compared with those with no exposure. Exposure to hot and cold takeaways was only significantly associated with higher odds of type 2 diabetes at the second highest exposure category that we examined (1·076, 1·01-1·14; p=0·0171), representing a density of 0·75-2·15 units per km2. A protective effect with distance decay was observed: participants in the highest quintile of street distance to nearest ready-to-eat food outlet reported lower odds of type 2 diabetes than those in the lowest quintile (0·842, 0·78-0·91; p<0·0001 for restaurants and cafeterias; and 0·913, 0·85-0·98; p=0·0173 for hot and cold takeaways). These effects were most pronounced in overweight participants (p=0·0329), but there was no evidence of interaction by sex, income, or UK Biobank collection centre. Access to ready-to-eat food environments was positively associated with type 2 diabetes. Top-down policies aimed at minimising unhealthy food access could potentially reduce unhealthy consumption and risks of chronic diseases. Further long-term studies are needed to effectively guide such interventions. University of Hong Kong, UK Biobank, and UK Economic & Social Research Council.

Empleo de vancomicina tópica en la profilaxis de infección de herida de esternotomía: experiencia inicial

IntroductionTopical vancomycin has demonstrated effectiveness in decreasing the incidence of surgical wound infection; however, its usefulness in cardiac surgery remains in doubt. ObjectivesTo analyse the effectiveness of topical vancomycin in the reduction of sternal wound infection in cardiac surgery. Material and methodA retrospective observational study was conducted to compare the incidence of sternotomy infection in a cohort in which the usual antibiotic prophylaxis was used, with another cohort in which topical vancomycin was also used. ResultsA total of 525 patients were included in the study, with 47.43% in the group treated with vancomycin. The incidence of infection was significantly higher in the group without vancomycin (3.6% versus 10.1%), implying a relative risk of infection of 2.8 (95% CI; 1.35-5.83, p=.0035). The differences were statistically significant as regards the incidence of superficial and deep infections (p=.05), but did not reach statistical significance in organ-space infection (p=.22). The beneficial effect of vancomycin was maintained in a logistic regression model adjusted for possible confounding factors (smoking, re-operation, nephropathy, and NYHA functional grade class): odss ratio 3.48 (95% CI; 1.44-8.41, p=.006). Gramnegative microorganisms were the main causative agent in the vancomycin group (57.1%), whereas it was grampositive in the group without vancomycin (66.70%), although these differences did not reach statistical significance. ConclusionThe use of topical vancomycin decreases the incidence of superficial and deep sternotomy wound infections. Its use could lead to a change in the aetiological spectrum of sternal wound infection.

Flujometría doppler de arterias uterinas como predictor de macrosomia fetal

Objetivos: Determinar la relación entre el índice de pulsatilidad promedio de las arterias uterinas tomadas por ecografía engestantes entre las 11 a 14 y 20 a 26 semanas de gestación con la macrosomía neonatal. Materiales y métodos: Estudioprospectivo, longitudinal, analítico. Se incluyeron a 3,279 gestantes atendidas en el Instituto Nacional Materno Perinatal entre elperiodo 2011 a 2014, de los cuales 952 fueron pacientes captadas entre las 11 a 14 semanas y 2327 entre las 20 a 26 semanas,se formó dos grupos: 11 a 14 y 20 a 26 semanas; los pesos considerados para la comparación fueron: 3,600, 3,800, 4,000, 4,200y 4,400 gramos, se realizó una correlación por el método de Pearson, la significación estadística se realizó por medio de la pruebade Chi cuadrado para ambos grupos, para calcular la probabilidad de ocurrencia de los eventos se calculó el odss ratio y paraevaluar la precisión se utilizaron intervalos de confianza, posteriormente se construyó una curva ROC para precisar la sensibilidady la tasa de falsos positivos.

Safety of laparoscopic and open approaches for repair of the unilateral primary inguinal hernia: an analysis of short-term outcomes

BackgroundPrimary laparoscopic repair of unilateral inguinal hernias has not achieved widespread recognition mainly because of concerns over safety. MethodsProspective cohort study using the American College of Surgeons National Surgery Quality Improvement Program between 2005 and 2010. Complications in patients undergoing unilateral first-time, elective laparoscopic unilateral inguinal hernia repair (LIHR) were compared with open inguinal hernia repair (OIHR). ResultsOf 37,645 identified patients, 6,356 (16.9%) underwent LIHR and 31,289 (83.1%) underwent OIHR. Both groups had similar 30-day overall complications, major complications, and mortality rates: 62 (1.0%) vs 307 (1.0%), P = 1.00; 31 (.5%) vs 173 (.5%), P = .57; and 1 (.02%) vs 16 (.05%), P = .34, respectively. Using multivariable logistic regression, overall complications showed no difference, OR 1.01 (95% CI .76 to 1.34; P = .94), as did major complications, OR .90 (95% CI .61 to 1.34; P = .62), although favoring the LIHR group, where OR and CI represent the odss ratio and confidence intervals. ConclusionThese data demonstrate no significant difference between elective unilateral LIHR and OIHR with regard to 30-day morbidity and mortality.

Phylogenetic Analysis and Prevalence of Human Papillomavirus (HPV) in Women with Several Cervical Pathologies

and HPV type 16 specific probe. HPV types determinate by GP5+/GP6+. Phylogenetic analysis of sequences was calculated by Kimura's two parameters method. Statistically analyses were by using Pearson chi-square and odss ratio tests. Results: Forty seven samples (prevalence; 61%) of total seventy seven cervical samples detected as HPV DNA positive. While HPV type 16; 52%, HPV type 16+11; 4%, HPV type 16+6; 1% and non-typing HPV DNA 4% of seventy seven samples determining, 39% of samples observed as negative HPV. Participated in the study population, HPV DNA positive individuals are among 34-56 years. Most HPV DNA positivity rate of 80.0% was between the ages of 3140. 52.2% of HPV DNA positivity between the ages of 41-50 to fall, but again, 83.3% between the ages of 51-60 to a second peak was determined that increased. 60.0% of 20 ASC-H cases, 63.8% of 36 ASC-US cases, 100% 9 of HSIL cases and 25.0% of 12 LSIL cases were positive for HPV DNA. Conclusion: The investigation of the distribution of HPV genotypes in women with cervical cancer and precancerous lesions in our region is important. Early diagnosis of HPV by using improved technological assays, play a key role to prevent the turn precancerous lesions into invasive cancers.

055 Predictive factors of renal failure in people hospitalized for acute coronary syndrome ST (-)

Objective The purpose of this study is to try to identify predictive factors of renal failure in hospitalized patients for acute coronary syndrome ST (-) in a mono-centric study. Material and method This is a retrospective, descriptive study, conducted in the cardiology service of the Beni Messous near hospitalized patients from 1 December 2007 to 30decembre 2008 for acute coronary syndrome. A number of 163 patients was included, aged between 41–92 years with an average age of 62 years. Results Analysis of results: Univariate analysis: the patients with impaired kidney are most often male, older, with more important. smoking and a more pronounced dyslipidemia, for the other variables studied (hypertension, diabetes, BMI, fraction ejection) the difference is not significant. Multivariate analysis: the only parameters that appear significant among hospitalized patients are: age, gender and dyslipidemia). Univariate analysis variable Ci 95% Odss ratio P-value Age 0.19–0.68 0.36 0.001 gender 0.26–0.91 0.49 0.022 tobacco 1.05–5.0 2.3 0.035 dyslipidemia 0.19–0.68 0.37 0.001 Multivariate Analysis variable ci 95% Odss ratio P-value Age 0.217–0.837 0.36 0.013 gender 0.26–0.91 0.49 0.058 dyslipidemia 0.185–0.735 0.37 0.004

The irritable uterus: A risk factor for preterm birth?

OBJECTIVE: Our aim was to determine the incidence and preterm delivery rate along with the indication for delivery in patients with uterine irritability. STUDY POPULATION: In this retrospective, descriptive study, 17,186 patients with well-defined high-risk factors were compared with 2637 women with uterine irritability. RESULTS: The incidence of preterm labor in patients with uterine irritability was 18.7%, significantly less than in those with other high-risk factors (odds ratio 0.35, 0.31 < odds ratio < 0.38). However, women with uterine irritability who experience preterm labor, compared with other high-risk factors, are much more likely to deliver before 34 weeks' gestation (odds ratio 2.50, 2.07 < odds ratio < 3.03) and more than twice as likely to deliver as a result of advanced preterm labor or membrane rupture (odss ratio 2.20, 1.75 < odds ratio < 2.78). CONCLUSIONS: The incidence of preterm labor in women with uterine irritability is not as frequent as in patients with other high-risk factors. However, preterm labor does occur in patients with uterine irritability at a rate higher than that in the general obstetric population (18.7% vs 11.0%). Because it appears that women with uterine irritability have more resistance to conventional tocolytic therapy, this condition should prompt the physician to use more aggressive perinatal assessment.