Occurrence Of Hexabromocyclododecane Research Articles

Occurrence of hexabromocyclododecanes (HBCDs) and tetrabromobisphenol A (TBBPA) in indoor dust from different microenvironments: levels, profiles, and human exposure.

The levels and distributions of hexabromocyclododecane diastereoisomers (HBCDs) (including α, β, and γ-HBCD) and tetrabromobisphenol A (TBBPA) were investigated in indoor dust from bedrooms and offices. HBCDs diastereoisomers were the most abundant compounds in the dust samples, and the concentrations of ∑HBCDs in the bedrooms and offices ranged from 10.6 to 290.1ng/g and 17.6 to 1521.9ng/g, respectively. The concentrations of target compounds in the offices were generally higher than those in the bedrooms, probably due to the presence of more electrical equipment in the offices. In this study, highest levels of target compounds were all found in the electronics. In the bedrooms, the highest mean level of ∑HBCDs was found in air conditioning filter dust (118.57ng/g), while the personal computer table surface dust showed the peak mean concentrations of ∑HBCDs (290.74ng/g) and TBBPA (539.69ng/g) in the offices. Interestingly, a significantly positive correlation was observed between the concentrations of ∑HBCDs in windowsills and beddings dust in the bedrooms, suggesting beddings was one of the crucial sources of ∑HBCDs in the bedrooms. The high dust ingestion values of ∑HBCDs and TBBPA were 0.046 and 0.086ng/kgbw/day for adults, while 0.811 and 0.04ng/kgbw/day for toddlers, respectively. The high dermal exposure values of ∑HBCDs were 0.026 and 0.226ng/kgbw/day for adults and toddlers, respectively. Except for dust ingestion, other human exposure pathways (such as the dermal contact with beddings and furniture) should be paid attention.

The effects of prosperity indices and land use indicators of an urban conurbation on the occurrence of hexabromocyclododecanes and tetrabromobisphenol A in surface soil in South China

Hexabromocyclododecane (HBCD) and tetrabromobisphenol A (TBBPA) are legacy brominated flame retardants which are still produced and used in China. In this study, 187 surface soils from the Pearl River Delta (PRD) urban conurbation in China were collected, and the effects of urban conurbation development on the concentrations, distributions and human exposure risk of HBCDs and TBBPA were investigated. The concentration ranges of Σ3HBCD (sum of α-, β-, and γ-HBCD) and TBBPA in soil were below the limit of quantification (<LOQ) to 300 ng g−1 dry weight (dw) and < LOQ to 53.1 ng g−1 dw, respectively. Concentration levels of HBCDs and TBBPA in the PRD were affected both by distributions of land-use type and by the location of the city. Soils from residential areas contained the highest concentrations of Σ3HBCD (median: 1.75 ng g−1 dw) and TBBPA (1.92 ng g−1 dw) among all land-use types. In addition, soils from the central PRD had higher Σ3HBCD and TBBPA levels (0.46 and 0.90 ng g−1 dw) than those from the surrounding areas (0.17 and 0.07 ng g−1 dw). The concentrations of Σ3HBCD and TBBPA were highly correlated with urbanization level, population density, regional GDP and per capita income in all cities studied (p < 0.01), which indicates that the prosperity of the urban conurbation may play an important role in soil contamination of HBCDs and TBBPA in the PRD. Children living in residential areas had the highest estimated daily intakes of Σ3HBCD (7.09 pg kg−1 d−1) and TBBPA (7.76 pg kg−1 d−1), suggesting that people living in residential areas have a relatively higher exposure risk of HBCDs and TBBPA. This is a comprehensive study to report the effects of prosperity indices and land use indicators of an urban conurbation on the occurrence of HBCDs and TBBPA in soil in China.

Occurrence of hexabromocyclododecanes and tetrabromobisphenol A in fish and seafood from the sea of Sardinia – FAO 37.1.3 area: Their impact on human health within the European Union marine framework strategy directive

Levels of hexabromocyclododecane isomers α, β, γ, (HBCDDs) and tetrabromobisphenol A (TBBP-A) were determined in 24 representative samples of different wild fish and seafood species (benthic: N = 16; pelagic: N = 8) and 16 samples of farmed bivalve molluscs from the West Mediterranean Sea (FAO 37, 1.3 sub-area). An LC-MS/MS-based method with limits of quantification (LOQS) in the range of 0.01–0.05 ng g−1 fresh weight (fw) was utilized. While α HBCDD was found in 80% of the 24 wild species samples, β and γ congeners were found in 33% and 25%, respectively. ΣHBCDD content ranged from 0.03 (Aristeus antennatus) to 0.68 (Sardina pilchardus) ng g−1 fw as Upper Bound values across 2.00–4.46 trophic levels. In farmed molluscs, HBCDD congeners were always present and ranged from 0.22–0.52 ng g−1 fw, with the exception of one farm (1.23–2.06 ng g−1 fw), whose values suggest the presence of a regular emission source. TBBP-A levels always fell below the LOQ of 0.05 ng g−1 fw in all samples. The results are in good agreement with results of previous studies from the Mediterranean Sea. The Environmental Quality Standard for human health from fish and seafood local consumption was set at 165 μg g−1 fw. The Margin of Exposure of 490,020 as the ratio between the considered Health Based Guidance Level of 0.79 mg kg−1 body weight and the geo-referenced HBCDD intake (P95 fish and seafood intake; mean ΣHBCDD contamination) indicates no threat to food safety.

Occurrence of Hexabromocyclododecane in soil and road dust from mixed-land-use areas of Shanghai, China, and its implications for human exposure

Herein, the occurrence of three Hexabromocyclododecane (HBCDD) diastereoisomers in soil and road dust from the mixed-land-use areas in Shanghai was investigated. The total concentrations of HBCDDs (∑HBCDDs) in soil ranged from 0.30 to 249ngg−1dw, with a median level of 5.14ngg−1dw. For the road dust samples, the ΣHBCDD concentrations varied from 4.11 to 508ngg−1dw, with a median level of 23.4ngg−1dw. The levels of HBCDDs varied in different mixed-land-use areas. In soil, the levels of HBCDDs increased in the following sequence: residential area & agricultural area (R&A)<agricultural area & industrial area (A&I)<residential area & commercial area (R&C)<residential area & industrial area (R&I); the levels for the road dust were A&I<R&A<R&C<R&I. The proportions of α-HBCDD in road dust samples were significantly higher than those of α-HBCDD in the soil. For soil, the portion of α-HBCDD increased in the following sequence: R&I<A&I≈R&A<R&C, while that for the road dust was R&C<R&A<R&I<A&I. Significant correlations in the concentrations of HBCDDs between soil and road dust from R&C and R&I were found, which suggested that they may share similar sources in these regions. On the basis of the HBCDD concentrations of road dust and soil, the contributions of ingestion, dermal contact absorption and inhalation intake to total estimated daily intakes (EDIs) were estimated. The highest total EDIs of ∑HBCDDs (sum of ingestion, dermal contact absorption and inhalation intake) were 0.154, 7.5×10−2ngkg−1d−1 for infants from road dust and soil in R&I, respectively.