Burnout is a syndrome of emotional, physical, and mental exhaustion caused by excessive stress, commonly experienced by medical students. Contributing factors include lifestyle and personality. The Big Five Personality Theory (neuroticism, extraversion, openness, agreeableness, conscientiousness) helps explain individual personality traits. This study aims to determine the relationship between the Big Five personality traits and burnout among medical students. An observational analytical approach with a cross-sectional design was used, targeting fourth-year medical students at Swadaya Gunung Jati University in 2024. Consecutive sampling was employed, and data were analyzed using the C contingency coefficient test. Data collection involved a questionnaire. Results indicated that 15 out of 68 students (22.1%) experienced burnout, with most students falling into the openness and agreeableness categories. The analysis revealed a significant relationship between personality traits and burnout (p = 0.003; p < 0.05), with students exhibiting openness experiencing burnout more frequently than those with agreeableness traits. Specifically, 48.5% of students in the openness category, 38.2% in agreeableness, 10.3% in conscientiousness, and 2.9% in neuroticism experienced burnout. The findings demonstrate a correlation between personality traits and the occurrence of burnout.
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