Occurrence Of Asymptomatic Bacteriuria Research Articles

A STUDY OF PREVALENCE OF ASYMPTOMATIC BACTERIURIA AND ITS ANTIBIOTIC SENSITIVITY IN TYPE 2 DIABETIC WOMEN

Background: Aim: Current study aimed to study the prevalence of asymptomatic bacteriuria in type 2 diabetic women, and antibiotic sensitivity of causative organisms. Method: This is a cross-sectional study conducted on 100 type-2 diabetic women at Dr Pinnamaneni Siddhartha institute of medical sciences and research foundation. Prevalence of ASB in Type 2 diabetic Women, causative organisms and their antibiotic sensitivity, relation to patient's status Were studied. In this study, asymptomatic Results: bacteriuria was seen in 32% of the subjects. In This study, 18% of the participants were aged 30-40, 32% were aged 41-50, 21% were Aged 51-60, 23% were aged 61-70, 5% were aged 71-80, 1% were aged 81-90 years. The mean duration of diabetes of among the cases who had asymptomatic bacteriuria Was 9.28 ± 5.92 years and in cases without bacteriuria it was 7 ± 5.25 years. There was A statistically signicant association between the duration of diabetes & asymptomatic Bacteriuria. Occurrence of asymptomatic bacteriuria was signicantly higher in cases With longer duration of mean FBS observed in Cases with ASB was 161.71 ± 40.49and in cases without ASB it ranged between 72-220 And the mean was 117.38 ± 34.37. PPBS ranged from 162-328 in cases of ASB, The mean PPBS BS observed in cases with ASB was 249.75 ± 51.38 and in cases without ASB it ranged between 116-346 and the mean was 190.52 ± 47.90.SBP ranged from 100-180 In cases of ASB, The mean SBP observed in cases with ASB was 124.75 ± 17.82 and in Cases without ASB it ranged between 100- 190 and the mean was 130.38 ± 15.33. DBP Ranged from 70-110 in cases of ASB, The mean SBP observed in cases with ASB was 81.93 ± 10.64 and in cases without ASB it ranged between 70-110 and the mean was 84.91 ± 9

Factors associated with the occurrence of asymptomatic bacteriuria among pregnant women in Embakasi Central Sub-County, Nairobi County

Background: Asymptomatic bacteriuria (ASB) complications are the second leading cause of death in pregnant women globally, trailing only anaemia. Despite the fact that urinary tract infection (UTI) has been a threat to public health in Nairobi for the past five years, especially in the Embakasi Central sub-county, no studies on the occurrence of ASB and related factors have been conducted in Nairobi County.Methods: A descriptive cross-sectional analytical design study was conducted in five wards of Embakasi central sub-county, Nairobi County, Kenya. A questionnaire and routine urine microscopy were used to collect data from 369 expectant women attending ANC in selected facilities. independent t test and chi-square tests were between the independent and dependent variables at p≤0.05.Results: The respondents were 26 years old on average, majority of the women had attained secondary education (46.7%, n=172), were married (66%, n=241) and professed Christianity (72.2%, n=265). The proportion of women in employment (52%, n=192) was slightly higher than the unemployed (48%, n=175). The occurrence of ASB was significantly higher in first trimester as compared to the other trimesters (p=0.000). Also, the occurrence of ASB differed significantly by religion (p=0.002) and by employment status (p=0.003). Most of the expectant mothers had heard of ASB, mainly from health care workers (58.9%, n=119) or the media (31.7%, n=64). ASB was more likely to occur in women who had never heard of ASB (p=0.000).Conclusions: The prevalence of ASB is relatively higher than the rest of the African continent. Knowledge levels, religion, family sizes, trimester of pregnancy and employment status were strongly linked to ASB. Consequently, a number of interventions and policy recommendations have been made in this paper.

Asymptomatic Bacteriuria among Pregnant Women in Addis Ababa, Ethiopia: Prevalence, Causal Agents, and Their Antimicrobial Susceptibility.

Asymptomatic bacteriuria (ASBU) is an important health problem among pregnant women, particularly in low-income countries. This study aimed to estimate the prevalence of ASBU and potential risk factors among pregnant women attending antenatal care centers in Addis Ababa. It also aimed to identify causal bacterial pathogens and to assess their antimicrobial susceptibility. A health facility-based cross-sectional study was conducted from March to June 2019. Urine samples from a total of 281 pregnant women with no symptoms of urinary tract infection were tested for ASBU. Women whose urine samples carried greater than or equal to 105 colony-forming units (CFU) of bacteria per milliliter of urine when grown on plate count agar were considered positive for ASBU. Bacterial pathogens were isolated from urine samples of women with ASBU using standard microbiological techniques. Antimicrobial susceptibility of isolates was investigated using the Kirby–Bauer disk diffusion method on Muller–Hinton agar plates. Of 281 pregnant women examined, 44 (15.7%) were positive for ASBU. Logistic regression analysis of the putative risk factors tested in the current study showed that none of them were significantly associated with the occurrence of ASBU (p > 0.05). The most frequently isolated bacterial species were Escherichia coli 17 (30.2%), Proteus 13 (23.2%), and Enterococcus 11 (19.6%). All of the E. coli, Citrobacter, and Klebsiella isolates and 84.6% of Proteus were resistant to ampicillin. All bacterial isolates were resistant to at least one of the antimicrobials tested. Resistance to three or more antimicrobials was detected in 15 (88.2%) of E. coli, 13 (100%) of Proteus, and 8 (72.7%) of Enterococcus isolates. Resistance to as many as 7 antimicrobials among E. coli, 8 antimicrobials among Proteus, and 7 antimicrobials among Enterococcus isolates was recorded. Detection of ASBU in a substantial number of pregnant women in this study warrants the need for a detailed study on possible risks of developing symptomatic urinary tract infection (UTI) and associated complications. Multidrug resistance to several antimicrobials was observed in the majority of bacterial isolates. Regular assessment of antimicrobial susceptibility of uropathogens to commonly prescribed antimicrobials and implementation of prudent use of antimicrobials are recommended.

Asymptomatic Bacteriuria and its Antibiotic Susceptibility Patterns among Pregnant Women in a Tertiary Care Center

Background: Occurrence of asymptomatic bacteriuria (ASB) in 2–11% of pregnant women is a major predisposition to the development of pyelonephritis, which is associated with significant maternal and fetal complications. Aim : The aim of this study was to determine the prevalence of ASB among pregnant women, to report the most common organisms causing ASB, along with their antibiotic sensitivity patterns. Materials and Methods A total of 250 asymptomatic pregnant women were screened for ASB by urine culture by standard microbiological procedures and the antibiotic sensitivity patterns recorded. Results Of the 250 pregnant women screened, 27 (10.8%) had ASB. The most common organism was Escherichia coli (52%) followed by Klebsiella pneumoniae and Staphylococcus aureus (19%). Majority of the uropathogens were found to be sensitive to nitrofurantoin (81%) and ciprofloxacin (63%). Conclusions: The high prevalence of ASB among pregnant women (10.8%) in our center demands the need for routine screening of the pregnant women and treat them appropriately, to reduce the risk of complications associated with ASB.

The necessity of treating asymptomatic bacteriuria with antibiotics in the perioperative period of joint arthroplasty: a metaanalysis

Background/aimOral antibiotics are usually used to treat asymptomatic bacteriuria during the perioperative period of joint replacement. However, there is no unified conclusion as to whether asymptomatic bacteriuria causes infection around joint prostheses, and the efficacy of antibiotics is unknown.Materials and methodsWe systematically searched PubMed, CNKI, Ovid, Cochrane Library, EMBASE, manual research, and references of relevant articles up to January 1, 2020, to identify and compare observational studies. The Cochrane systematic review method was used, and Review Manager 5.3 software was used for analysis.ResultsNine articles were included in the analysis, involving 29,844 cases of joint arthroplasty and 2366 cases of asymptomatic bacteriuria. Periprosthetic joint infection had a significantly higher incidence in the asymptomatic bacteriuria group than in the nonasymptomatic bacteriuria group (Odds Ratio: OR = 3.15, 95% CI: 1.23–8.02, P = 0.02). Seven of the nine articles reported the use of antibiotics for treating perioperative asymptomatic bacteriuria and there was no significant difference in the incidence of periprosthetic joint infection between the two groups (OR = 1.64, 95% CI: 0.84–3.23, P = 0.15). ConclusionThe occurrence of asymptomatic bacteriuria in the perioperative period of joint arthroplasty is a risk factor for periprosthetic joint infection, and the use of antibiotics for asymptomatic bacteriuria does not change the rate of incidence.

Asymptomatic bacteriuria among antenatal clients in a secondary facility in southwestern Nigeria

Context: Asymptomatic bacteriuria (ASB) is the presence of bacteria in the properly collected urine of a patient that has no signs or symptoms of a urinary tract infection (UTI). If diagnosed early, UTI and its grave consequences can be prevented in pregnant women. Aims: The goal was to ascertain the prevalence of ASB in pregnant women attending antenatal clinic. Subjects and Methods: The study was a cross-sectional descriptive study. Data were collected using the proforma. Clean catch urine samples were taken and sent for microscopy, culture, and sensitivity. The data were analyzed by statistical package for social sciences (SPSS) version 23. Results: A total of 42 women had ASB on urine culture, giving a prevalence of 30.4%. The most common organism cultured was Escherichia coli (21[50%]) and most of the organisms isolated were sensitive to nitrofurantoin (88.3%). Conclusions: This study found that the prevalence of ASB among antenatal clients was 30.4%. The dominant organism was found to be E. coli. Majority of the organisms were sensitive to nitrofurantoin (88.3%), cefuroxime (78.6%), ceftazidime (78.6%), and ceftriaxone (71.4%). We found a positive association between the density/number of urinary pus cells of the participants and the occurrence of ASB.

Asymptomatic bacteriuria in a university teaching hospital in Southern Nigeria: Prevalence, uropathogens, and antibiotic susceptibility

Background: Asymptomatic bacteriuria (ASB) has been documented as the main risk factor for the development of symptomatic urinary tract infection in pregnancy and is associated with maternal and fetal complications. Objective: To determine the ASB prevalence, the causative microorganisms, their drug sensitivity patterns, and the factors associated with its occurrence in pregnant women in the Uyo, Nigeria. Methodology: Three hundred and twenty women were recruited during their first antenatal visit over a period of 13 weeks. A midstream urine specimen was obtained from each patient, cultured, isolates identified and antimicrobial sensitivity done. Data were analyzed using the Statistical Package for the Social Sciences version 20. Results: The ASB prevalence was 9.1% with the two commonest identified isolates being Escherichia coli (41.4%) and Klebsiella pneumoniae (24.1%). Imipenem (100.0%) and gentamycin (37.9%) were the two most sensitive drugs. The association between respondents' educational level and the occurrence of ASB was significant statistically. Conclusion: The prevalence of ASB was relatively high among the respondents. This, therefore, emphasizes the need for routine screening of our antenatal female population for ASB in all our health facilities.

Occurrence of Asymptomatic Bacteriuria amongst Inmates of Federal Neuropsychiatric Hospital Calabar, Nigeria

Occurrence of Asymptomatic Bacteriuria amongst Inmates of Federal Neuropsychiatric Hospital Calabar, Nigeria

Epidemiological Survey of Asymptomatic Bacteriuria in Diabetes Mellitus Patients in Patna, India

To determine the prevalence and etiology of Asymptomatic bacteriuria (ASB) and antimicrobial resistance of urinary isolates among diabetics mellitus and non-diabetics, a total of 200 patients comprising of 120 diabetes mellitus (DM) and 80 non- diabetes were studied. ASB was detected in 36% patients of which 40% are diabetic and 30% are non-diabetic. Coagulase Negative Staphylococcus (CoNS) were the predominant organism (36.36%) isolated from the urine of both diabetic and non-diabetic. We observed occurrence of ASB significantly increases with age in DM patients and is more prevalent in DM females compared to non-DM females. Whereas Klebsiella sp., Candida sp., and E. coli were also significantly more prominent in DM patients. Most isolates of Klebsiella sp. and E. coli showed resistances to multiple antibiotics tested. For the uropathogens found in the samples tested Levofloxacin proved to be the most sensitive antibiotic. The study revealed a high prevalence of ASB among DM than non-DM subjects. This study also demonstrates multiple drug resistance observed in both DM and non-DM subjects, therefore irrational and indiscriminate use of antibiotic should be avoided.

Comparison of silver alloy catheter with standard catheter in preventing urinary tract infection: a meta-analysis

Objective To evaluate the clinical effect of silver alloy catheter in preventing the urinary tract infection by meta-analysis.Methods The following databases,including Cochrane Library,PubMed,Embase,China Biology Medicine,China National Knowledge Infrastructure,VIP Information Chinese Science and Wanfang Data Knowledge Service Platform,were searched from the time of those database set to November 16,2012.And the other sources,such as tracing related references,were also retrieved.All randomized controlled trials (RCTs),concerning silver alloy catheter versus standard catheter (including latex catheter,silicone catheter,silicon latex catheters,silicon rubber catheter,poly tetra fluoro ethylene (PTFE) coated catheter),were collected to evaluate the incidence of urinary tract infection during shortterm catheterization (＜30 d).The literatures were screened according to selection criteria.Data extraction and study quality evaluation were independently reviewed.Then the meta-analysis was conducted by using RevMan 5.1 software,and the odds ratio (OR) and 95％CI were calculated in both the study group (silver alloy catheter group) and control group (standard catheter group).Results A total of 13 RCTs,and 6 634 patients were included.Meta-analysis results showed that the incidence of asymptomatic bacteriuria in silver alloy catheter group was significantly less than latex catheter group [OR =0.30,95％CI (0.23,0.40),P=0.00],silicone catheter group [OR =0.68,95％CI (0.51,0.91),P=0.01],and ordinary catheter group(silicon latex / silicon rubber catheter) [OR =0.17,95％ CI (0.09,0.31),P =0.00].There was no significant difference in the occurrence of symptomatic urinary tract infection between silver alloy catheter group and PTFE catheter group [OR=0.99,95％CI (0.83,1.19),P=0.92].Comparing with the standard catheter group,a significant difference in the occurrence of urethral discomfort could be noticed in the silver alloy catheter group [OR =0.82,95％ CI (0.70,0.95),P =0.01].However,the signicant difference did not appeare in the occurrence of pain between those 2 groups [OR=0.72,95％CI (0.30,1.75),P=0.47].Conclusions Compared with the standard catheter,silver alloy catheter cannot reduce the incidence of symptomatic urinary tract infection.But silver alloy catheter is superior to standard catheter in reducing the occurrence of asymptomatic bacteriuria and increasing the comfort level of patient. Key words: Urinary tract infections; Urinary catheter; Silver; Meta-analysis; Randomized controlled trials