Research Object Research Articles

A novel tRNA-derived fragment tRF-17-18VBY9M works as a potential diagnostic biomarker for gastric cancer.

Gastric cancer (GC) is one of the most prevalent malignant tumors worldwide. The low effectiveness of common biomarkers for the detection of early GC makes it essential to seek new biomarkers to improve diagnostic efficacy. tsRNAs (transfer RNA-derived small RNAs) are related to the growth of malignant tumors. In this article, we focused on whether tsRNAs may be employed as biomarkers for GC. tRF-17-18VBY9M was screened in the tsRFun database as a research object. The methodological efficacy of tRF-17-18VBY9M was evaluated using Sanger sequencing, agarose gel electrophoresis assays, and gradient dilution. The χ2 test was applied to assess the interaction between tRF-17-18VBY9M expression and clinicopathologic characteristics. The receiver operating characteristic (ROC) curve was utilized to investigate the clinicalefficiency of tRF-17-18VBY9M in GC. The Chi-square test demonstrated that high-expressed tRF-17-18VBY9M was closely associated with the T stage, tumor node metastasis stage (TNM), lymph node metastasis, and neurological/vascular invasion. ROC curve analysis revealed that the diagnostic value of tRF-17-18VBY9M in GC was superior to carcinoembryonic antigen (CEA), carbohydrate antigen 199 (CA199), and carbohydrate antigen 724 (CA724). tRF-17-18VBY9M is up-regulated in both GC sera and tissues. Differential tRF-17-18VBY9M expression distinguishes GC patients from healthy donors and gastritis patients, which suggests tRF-17-18VBY9M could act as a diagnostic biomarker in GC.

Study on the gut symbiotic microbiota in long- and short-winged brown planthopper, Nilaparvata lugens (Stål).

The brown planthopper (BPH), Nilaparvata lugens (Stål), is one of the most important rice pests in Asia rice regions. BPH has monophagy, migration, rapid reproduction and strong environmental adaptability, and its control is a major problem in pest management. Adult BPH exhibit wing dimorphism, and the symbiotic microbiota enriched in the gut can provide energy for wing flight muscles as a source of nutrition. In order to study the diversity of symbiotic microbiota in different winged BPHs, this paper takes female BPH as the research object. It was found that the number of symbiotic microbiota of different winged BPHs would change at different development stages. Then, based on the 16S rRNA and ITS sequences, a metagenomic library was constructed, combined with fluorescent quantitative PCR and high-throughput sequencing, the dominant symbiotic microbiota flora in the gut of different winged BPHs was found, and the community structure and composition of symbiotic microbiota in different winged BPHs were further determined. Together, our results preliminarily revealed that symbiotic microbiota in the gut of BPHs have certain effects on wing morphology, and understanding the mechanisms underlying wing morph differentiation will clarify how nutritional factors or environmental cues alter or regulate physiological and metabolic pathways. These findings also establish a theoretical basis for subsequent explorations into BPH-symbiont interplay.

Exploring Cognitive Behavioral Aspects in Educational Psychology: A Rigorous Analysis of Reliability and Validity Measures.

The purpose of this study is to verify the reliability and effectiveness of an educational psychology scale, which is explored by using the methods of literature, interview, questionnaire survey and mathematical statistics. The research object is the education psychology data of undergraduate students in local undergraduate colleges and universities.The data are collected and analyzed through the scale. The results show that the educational psychology scale contains six dimensions, including self-efficacy, learning motivation, hope trait, psychological resilience, physical self-esteem and emotional management, with a total of 27 items. The kmo sampling appropriateness of the scale is 0.800. The load of six dimensions in the total amount table is between 0.58 and 0.73. The fitting coefficient of each item of the structural model is between 0.45-0.73, and the correlation between each dimension and the total table is between 0.24-0.52. Scale cronbach's α The coefficient was 0.83 and the test-retest reliability was 0.90. The content validity of the scale ranged from 0.554 to 0.775. The scale has good reliability and validity, and can be used to evaluate undergraduate students' educational psychology.

Analysis of factors influencing college students’ food waste behavior and evaluation of labor education intervention

BackgroundFood waste remains a major problem for the world and food security. Despite the fact that consumers are significant producers of food waste, little research attention has been paid to college students. The present study aimed to assess food waste and the influence factors among college students. Additionally, the goal was to improve college students’ food waste attitudes and behaviors through labor education.MethodsThrough an online questionnaire survey, 407 college students from three universities were asked about food waste; 27 students of them were randomly selected as the research object, and labor practice was carried out in groups in the student cafeteria. Mann–Whitney U test was performed to show food waste behavior of college students and logistical regression analysis was used to analyze the factors affecting food waste behavior.ResultsThe results indicated that the food waste is more serious among college students in East China, senior or female students, BMI plays a positive role in food waste among college students, while monthly consumption and peers waste play a negative role in food waste. After participating in the labor education, the students’ views and practices toward their peer’s food waste have improved.ConclusionThe implementation of labor education in college canteens is conducive to the establishment of a correct outlook on labor as well as saving consciousness among college students, and to the formation of a social consciousness of saving.

A New Machine-Learning-Driven Grade-Point Average Prediction Approach for College Students Incorporating Psychological Evaluations in the Post-COVID-19 Era

With the rapid development of artificial intelligence in recent years, intelligent evaluation of college students’ growth by means of the monitoring data from training processes is becoming a promising technique in the field intelligent education. Current studies, however, tend to utilize course grades, which are objective, to predict students’ grade-point averages (GPAs), but usually neglect subjective factors like psychological resilience. To solve this problem, this paper takes mechanical engineering as the research object, and proposes a new machine-learning-driven GPA prediction approach to evaluate the academic performance of engineering students by incorporating psychological evaluation data into basic course scores. Specifically, this paper adopts SCL-90 psychological assessment data collected in the freshman year, including key mental health indicators such as somatization, depression, hostility, and interpersonal sensitivity indicators, as well as professional basic course scores, including mechanical principles, mechanical design, advanced mathematics, and engineering drawing. Four representative machine learning algorithms, Support Vector Machine (SVM), CNN-CBAM, Extreme Gradient Boosting (XGBoost) and Classification and Regression Tree (CART) that include deep and shallow models, respectively, are then employed to build a classification model for GPA prediction. This paper designs a validation experiment by tracking 229 students from the 2020 class from the School of Mechanical and Electrical Engineering of Henan University of Science and Technology, China. The students’ academic performance in senior grades is divided into five classes to use as the prediction labels. It is verified that psychological data and course data can be effectively integrated into GPA prediction for college students, with an accuracy rate of 83.64%. Meanwhile, this paper also reveals that anxiety indicators in the psychological assessment data have the greatest impact on college students’ academic performance, followed by interpersonal sensitivity. The experimental results also show that, for predicting junior year GPAs, psychological factors play more important role than they do in predicting sophomore GPAs. Suggestions are therefore given: the current practice in existing undergraduate teaching, i.e., only conducting psychological assessments in the initial freshman year, should be updated by introducing follow-up psychological assessments in each academic year.

How the ecological structure affects the aesthetic atmosphere of the landscape: Evaluation of the landscape Beauty of Xingqing Palace Park in Xi'an.

In landscape appreciation, what tourists directly perceive is the atmosphere of the landscape. This paper introduces the concept of "Ecological Structure" from Gernot Böhme's theory of atmospheric aesthetics into the assessment of landscapes, utilizing atmosphere as a bridge between horticultural ecology, aesthetics, and culture. It examines the relationship between the objective environment and subjective perception. This study conducted a field survey of Xingqing Palace Park and selected the waterside plant landscape that directly reflects the atmosphere of the royal garden as the research object. In the first stage of this study, Scenic Beauty Estimation was used to evaluate the overall beauty of 32 landscape units; in the second stage, the Delphi method and Analytic Hierarchy Process were used to evaluate the ecological structures that affect the garden landscape atmosphere; in the third stage, the two evaluation results of the Kendall's W concord coefficient test Analytic Hierarchy Process and Scenic Beauty Estimation have high consistency, which shows that the atmosphere is great value to the beauty of the landscape. This study provides designers with a means to create a garden atmosphere using ecological structures and provides new ideas for landscape design.

Исследование физико-механических свойств сгущенных хвостов обогащения и формируемого искусственного массива в выработанном пространстве карьера

The article presents the results of studying physical and mechanical properties of thickened concentration tailings, as well as regularities in their changes during the dumping process in mined-out spaces of open-pits. The necessity of experimental studies is explained by the existing discrepancy between the parameters of the artificial hydraulic deposition of soils and the design solutions, in particular, the spreading angles, the lack of a ponding zone created within the rock mass body, as well as the insignificant influence on the intakes of the dewatering plant. The following characteristics of the thickened tailings that define the parameters of the hydraulic deposition technology and the artificial massif formed inside the pit at the design stage were taken as the research objects: density, mineral density, absolute and relative moisture content, storactivity, viscosity, shear stress, flowing angle, and water conductivity. These characteristics were tested using conventional methods. Representative samples were collected at the discharge points of the thickened tailings in the open pit and directly at the discharge point of the thickener No.2 at the paste thickening plant. It was established that as the thickened tailings are transported to the place of their deposition inside the open pit, no changes take place in their density, moisture content, and water conductivity, but the rheological properties, such as viscosity, shear stress, angle of spreading undergo a significant change, which should be taken into account in design solutions. Being familiar with the technology of thickening, transportation and storage of paste mixtures in open-pit mines allows us to consider the mechanical impact on the pulp flocculi and their destruction, consisting in the rupture of the macromolecules, as the main cause of changes in the structure and properties of the thickened tailings.

Evaluation of the Ecological Environment of the Fuhe River Based on the Diversity of Fish

This article takes the Fuhe River, which has water flowing into Baiyangdian all year round, as the research object. Through actual investigation and measurement of planktonic flora and fauna, benthic organisms, fish, and large vascular plants in the river, and based on fish diversity, the comprehensive evaluation index method is used to scientifically evaluate the ecological environment quality of the Fuhe River. The results showed that a total of 28 species of phytoplankton, 30 species of zooplankton, 11 species of benthic animals, 8 species of submerged plants, and 11 species of fish were detected in the survey area; From a diversity perspective, the diversity of the upstream and downstream river sections is higher than that of the downstream. Overall, the ecological environment quality of the Fuhe River in Baoding City ranges from medium to good, with good water quality in the upstream section and moderate water quality in the middle and downstream sections. This study provides a case study for the scientific evaluation of the ecological environment quality of the upper reaches of Baiyangdian.

PENGARUH HARGA DAN KUALITAS PRODUK TERHADAP KEPUTUSAN PEMBELIAN PRODUK BITTERSWEET BY NAJLA DENGAN KEPUASAN KOSUMEN SEBAGAI VARIABEL MEDIASI

The research was conducted by measuring the influence that product price and quality have on purchasing decisions by paying attention to consumer satisfaction as a mediating variable. Furthermore, bittersweet by Najla was chosen as the research object because of its popularity. Through the purposive sampling method, measurements using quantitative methods were obtained by distributing questionnaires to consumers of Bittersweet Najla who are 15 years old, as well as people who like sweet foods, so a total of 175 respondents were obtained. The findings show that customer satisfaction and price and product quality influence purchasing decisions, not only a direct influence but also a mediating influence on consumer satisfaction which also has a significant impact on the relationship between price and product quality on purchasing decisions. Key words: Price, Product Quality, Purchasing Decisions, Consumer Satisfaction

Delegation of Medical Action Authority of Doctors to Nurses in Health Services in Emergency Departments: Empirical Legal

Purpose: This study aims to analyze the implementation of the delegation of authority of medical actions of doctors to nurses in the emergency department and explore the legal responsibility of the delegation of authority of medical actions of doctors to nurses in the emergency department in Indonesia. Theoretical Fremework: Theoretically, this research is expected to contribute intellectually and academically to the enhancement of understanding of healthcare laws for healthcare practitioners, institutional leaders, and to provide a sense of security and protection in carrying out healthcare services functions to the community, especially in the provision of medical procedures at healthcare facilities. Additionally, it is expected to provide practical insights for the goverment, hospital directors, and health departments in order to improve healthcare services to the public and ensure legal protection for healthcare workers in carrying out their professional duties. Method: The type of research method used is empirical legal research. Data primarily obtained from respondents using a list of questions (questionnaire) and direct interviews with the research object. In addition to that, it is also based on legal materials that are relevant to the discussion or problem being researched and other supplementary legal materials that can provide explanations. Results: The delegation of medical action authority from doctors to nurses in healthcare services at emergency rooms is regulated in Article 290 of Law Number 17 of 2023 concerning Health. Medical and healthcare services, consisting of both mandatory delegation. The scope of work delegated through partnership must be clearly and specifically defined in writing within the authority delegation letter and adjusted according to the level of competence of the nurse. The doctor as the delegator and the nurse as the recipient of medical authority there are also responsibilities of the hospital, as well as the central and local governments, especially in meeting the national needs for medical and healthcare personnel. In handling medical dispute cases, law enforcement agencies must prioritize the mechanism of restorative justice. If no agreement is reached, the dispute is then taken over by the professional disciplinary board under the Ministry of Health to determine whether there has been any violation of professional discipline by medical and healthcare personnel. Conclusions: 1) Delegation of authority for doctor’s medical actions to nurses in health services in emergency departments in Indonesia, regulated in Law No. 17 of 2023 concerning Health Article 290, Minister of Health Regulation No. 2052 of 2011 Article 23 and Minister of Health Decree No. HK.01.07-425 of 2020 concerning Nursing Professional Standards; 2) Responsibilities by doctors, nurses, and hospitals regarding the delegation of authority for doctors’ medical actions to nurses in health services in emergency departments must be carried out by laws.

Clinical Results of Asymmetric Blepharoplasty Plastic Repair.

To investigate plastic surgery repair's effects and adverse reactions in the clinical therapy of asymmetric double eyelids. All 126 sufferers who came to the hospital for asymmetric double eyelid plastic repair from January 2022 to October 2022 were selected as the research objects, and they were divided into a control group and an observation group using the random number method, with 63 cases in each group, in which sufferers in the control group underwent full incision blepharoplasty and sufferers in the observation group underwent small incision liposuction with submerged sutures. The general data, treatment results, treatment satisfaction, related surgical indicators, and frequency of adverse reactions of the 2 groups of sufferers with asymmetric double eyelid plastic repair were compared. It had no statistically obvious distinction between the control group and the observation group of sufferers in terms of general data such as sex, age, weight, and height (P>0.05); the total therapy efficiency of the sufferers in the observation group (95.24%) was greater than the control group (74.60%), with P value <0.05; the total treatment satisfaction of the patients in the observation group (96.83%) was significantly higher than that in the control group (76.19%), with P value <0.05; compared with the control group, patients in the observation group had shorter operative time and healing time and less intraoperative bleeding, with P value <0.05; the total frequency of adverse reactions of sufferers in the observation group (4.76%) was less than the control group (17.46%), with P value <0.05. Small incision liposuction with submerged sutures for plastic repair has significant efficacy, relatively high patient satisfaction, and low incidence of adverse reactions, in line with patient esthetic review, which has a broad clinical application prospect.

The stuff of memories: Planning hindsight in animal cryobanks.

Biobanks are becoming ubiquitous infrastructures in zoology and other non-human life sciences. They promise to store frozen research samples for the long term for future use. That use remains speculative but nevertheless needs to be anticipated. Following the establishment of a physical and digital infrastructure for frozen samples in an animal biobanking project, this article explores how the future is anticipated to remember the past, and how frozen objects are shaped accordingly. Situating the biobank between mundane freezing routines in a research lab and the 'dry' and 'wet' collections of natural history museums, I argue that frozen research objects need to be conserved in two separate ways. The unavailability of cryo-objects in cold storage forces researchers to store materials independently of metadata, while retaining a link between them that allows for their reunion after thawing. The result is a split object, leading a double life at sub-zero and room temperature, linked only through the surface of special plastic containers. Following the making of such split objects, this article offers an elaboration of Radin's 'planned hindsight' as well as a reflection on the universality and particularity of biobanks as standardized scientific memory.

IMPLEMENTASI METODE UMMI DALAM MENGATASI KESULITAN MEMBACA DAN MENGHAFAL AL-QUR’AN DI RUMAH QUR’AN HIDAYATUL HAQ SINJAI

The study in the article can review how to implement the Ummi Method to avoid difficulties when reading and memorizing the Koran at the Hidayatul Haq Sinjai Qur'an House. The type of research used is qualitative research using a phenomenological approach and the data sources in this research are teachers (ustadz/ustazah), heads of Qur'an houses, students and other information related to this research. Collecting data was carried out by means of observation, interviews and documentation. In analyzing this data, researchers used qualitative data analysis techniques to process raw data from the field to increase understanding of the research object. Data Presentation: At this stage, carry out analysis by summarizing the data and drawing conclusions. The results of the research are data regardin.g how the Ummi method is implemented in the Qur'an house. They consider that this method is very effective because sentences or films that are continuously given repeatedly to students will indirectly be embedded in their brains until they understand. Apart from that, this method is also easy, fun and touching, meaning that children enjoy using this method.

Analysis of Energy Consumption and Economy of Regional Gas Tri-Supply Composite System

With the development of Chinese society, there is an increasing demand for emissions reduction and the stable operation of the power grid. Regional comprehensive energy supply systems have entered the public’s view owing to their advantages of reducing capacity, unified dispatch, improving efficiency, and reducing energy consumption. This paper focuses on a system under construction in Chongqing, which adopts a combined gas tri-supply (combined cooling, heat, and power, CCHP) and dynamic ice storage cooling system as the research object. By establishing a mathematical model for the simulation research, this study examines the start–stop priority sequence of the gas tri-supply subsystem and the heat pump subsystem under the ice storage priority strategy in winter and summer and proposes corresponding optimization solutions. By comparing the annual operating energy consumption of the system, we conclude that the gas tri-supply composite system has good economic efficiency and peak-shaving capability, indicating that regional gas tri-supply composite systems have great application potential in the future. The proposed optimized operation strategy and simulated energy consumption calculation provide theoretical guidance for the construction and operation of both this project and similar projects.

Enhancing genome-wide populus trait prediction through deep convolutional neural networks.

As a promising model, genome-based plant breeding has greatly promoted the improvement of agronomic traits. Traditional methods typically adopt linear regression models with clear assumptions, neither obtaining the linkage between phenotype and genotype nor providing good ideas for modification. Nonlinear models are well characterized in capturing complex nonadditive effects, filling this gap under traditional methods. Taking populus as the research object, this paper constructs a deep learning method, DCNGP, which can effectively predict the traits including 65 phenotypes. The method was trained on three datasets, and compared with other four classic models-Bayesian ridge regression (BRR), Elastic Net, support vector regression, and dualCNN. The results show that DCNGP has five typical advantages in performance: strong prediction ability on multiple experimental datasets; the incorporation of batch normalization layers and Early-Stopping technology enhancing the generalization capabilities and prediction stability on test data; learning potent features from the data and thus circumventing the tedious steps of manual production; the introduction of a Gaussian Noise layer enhancing predictive capabilities in the case of inherent uncertainties or perturbations; fewer hyperparameters aiding to reduce tuning time across datasets and improve auto-search efficiency. In this way, DCNGP shows powerful predictive ability from genotype to phenotype, which provide an important theoretical reference for building more robust populus breeding programs.

Olympism and Chinese humanism: a critical analysis of the opening ceremony of the 2022 Beijing Winter Olympic Games

ABSTRACT The purpose of this study is to examine China’s discourse on uniting all ethnic groups internally and conveying the human community to the world in the opening ceremony of the 2022 Beijing Winter Olympics (BWO), reflecting the different Olympism of the East and the West and the intersection of Chinese humanism discourse to form the core concept of this study. In terms of research methods, this study took the opening ceremony of the BWO as the research object, collected the content of the opening ceremony of the 2022 BWO, media reports, and related academic research, and analyzed the discussion of the 2022 BWO at the opening ceremony. The results have shown that the BWO opening ceremony continues the Chinese humanism concept of the 2008 Beijing Olympics, showing the connotation of people-oriented patriotism and emphasizing the ideal of a community with a shared future for humanity in the world. This study concludes that the BWO opening ceremony emphasizes Chinese tradition, culture, and patriotism. At the same time, the opening ceremony’s theme is set as the concept of “One World, One Family.” This discourse has formed a contrast between cosmopolitanism and patriotism, which not only shows the contradiction in the internal discourse of Chinese humanism but also shows the dialogue’s dilemma between the Asian value thinking advocated by Chinese humanism and the universal values of individualism and human rights emphasized by Western concepts.

Exploring the Impact of Social Media on English Language Learning: Opportunities and Challenges

This study seeks to elaborate on the influence that social media presents in the learning of the English language in Pakistan, together with the opportunities and challenges influenced by the phenomenon. The research object was to understand how media in Pakistan influence educational dynamics and language development within everyday life. The growing dominion of the English language as the lingua franca of the world would, therefore, make educators and policymakers understand the role that social media plays as host for language learning. The data collection method for this study was therefore done through a mixed-method approach across Pakistan with 30 participants from different linguistic and cultural backgrounds. Methods to use social media and keeping users engaged with English content were studied and presented as an effective tool for the most recent method of upgrading language skills. Finding out from our respondents further reiterated this, as a good number of them (97%) found social media helpful in improving their English language through substantial involvement with content in English and gains made in vocabulary and grammar. Quality of language, however, remains a persistent challenge amid informal styles of communication. In other words, the study suggests that while social media is an effective supplementary tool for language learning, yet at the same time, it should be used with a degree of caution within formal educational frameworks to optimise the benefits. It is precisely this research, then, that highlights strategies that could fully exploit such an educational potential while mitigating social media's weaknesses to improve English language education in Pakistan and other similar settings.

Forecasting Coffee Exports to the United States Using the Holt-Winters Exponential Method

A study was conducted to estimate coffee exports to the United States using the Holt-Winters Exponential method. The aim of this research is to project coffee export activity over the next four periods. Data on coffee exports to the United States from 2000 to 2022 was obtained from the Indonesian Central Bureau of Statistics and used as a research object. The range of values used in this study is between 0.1 and 0.5 for α, between 0.1 and 0.5 for β, and between 0.1 and 0.9 for ϒ. The results of this research state that it is estimated that in 2023, Indonesia will export coffee to the United States amounting to 61,332.60 tons, in 2024 amounting to 60,661.50 tons, in 2025 amounting to 61,563.27 tons, and in 2026 amounting to 60,196.50 tons

Seismic behavior analysis of long-span cable-stayed bridge under bi-directional near-fault ground motions

In this paper, the seismic behaviors of a long-span cable-stayed bridge subjected to bi-directional near-fault ground motions are analyzed. The cable-stayed bridge with a main span of 432 m is selected as the research object and appropriately modeled using the OpenSees software. Ten sets of historical near-fault and far-field ground motions associated with the same earthquake event and site class are utilized as input excitations. Nonlinear time-history analyses are conducted to explore three key aspects: the influence of ground motion directionality, the effectiveness of the percentage rule and simplified Square-Root-of-Sum-of-Squares (SRSS) rule, and the main influential factors. The findings reveal that near-fault ground motions induce larger seismic responses compared to far-field ground motions. Moreover, the effects of ground motion directionality are more pronounced in near-fault scenarios than in far-field events. The percentage rule and simplified SRSS rule demonstrate minor significance in predicting the critical seismic responses. The bi-directional peak ground velocity (PGV) of seismic motions in the principal directions of the cable-stayed bridge may emerge as the primary factor influencing the seismic responses, making it a suitable intensity measure for bi-directional seismic fragility assessment.

Media Online Lokal dalam Menerapkan Jurnalisme Pariwisata (Studi Pada Media Online Lokal Bengkulu Ekspress)

Tourism journalism is a journalism practice that aims to report on tourist destinations in an area, both for promotion and information. The development of online media in the country is increasingly rapid, making online media ideal as the first platform for searching for information about tourist destinations in a place as well as information on available facilities and infrastructure. Bengkulu Ekspress as a pioneer of online media in Bengkulu Province has some of which are about tourism. The aim of this research is to find out how tourism journalism is implemented on the Bengkulu Ekspress online media channel. This research uses a qualitative descriptive method which describes the results of observations seen from the research object using the framing analysis method. The results of this research explain that Bengkulu Ekspress implements tourism journalism by applying a special rubric entitled Bengkulu Tourism and Culinary Tourism and the locality of the news presented by Bengkulu Ekspress.com makes news about tourist destinations more specific to the Bengkulu Province area only. Apart from that, Bengkulu Ekspress also provides information about accommodation and transportation with narratives that attract readers to imagine their travel estimates in tourism journalism reporting.