Abstract Background: Anemia is defined operationally as a reduction in the hemoglobin content of blood that can be caused by a decrease in red blood corpuscles, hemoglobin, and hematocrit below the reference interval for healthy individuals of similar age, sex, and race under similar environmental conditions. Megaloblastic anemia is a condition, in which the bone marrow produces unusually large, structurally abnormal, and immature red blood cell. World Health Organization identifies anemia as the most common nutritional deficiency disorder in the world and a serious health concern among pregnant women. The 2011 estimates suggest that anemia affects around 800 million children and women all over the world, including 273 million children, 496 million non-pregnant women, and 32 million pregnant women. Objective: To determine the prevalence of megaloblastic anemia in patients at NIMS Hospital, Jaipur, Rajasthan, India. Materials and Methods: Blood was collected and investigations are done on Elite 580. Results: Male patients were more likely than female individuals to have megaloblastic anemia. Only 62 patients were female, with 210 patients being men. Male patients made up 77.21% of the prevalence, while female patients made up 22.79%. Megaloblastic anemia is more common in people between the ages of 41 and 50, both in male and female patients. Between the ages of 41 and 50, there were 144 male patients and 35 female patients overall. According to their ages, the prevalence of mean ± standard deviation was 43.5 ± 15.6 years for male patients and 41.32 ± 6.53 years for female patients. Male patients with megaloblastic anemia had an average hemoglobin concentration of 9.990.94 g/dL, whereas female patients had one of 9.970.87 g/dL. Conclusion: Government of Rajasthan as well as Health Ministry of India should take appropriate action to control the megaloblastic anemia in patient. Megaloblastic anemia is a common anemia found in the rural parts of Jaipur. The present study helps physicians to take necessary steps to control it. Not only for physicians, it will also be helpful for the government authorities to take appropriate steps to prevent and control the megaloblastic anemia. Iron and vitamin B12 supplements should be given to the patients on right time to control megaloblastic anemia. A balanced diet should be taken to prevent it. Government should take steps to educate the peoples of Rajasthan by displaying posters, conducting educational dramas, etc., both in rural and in the urban parts of this state.
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