Number Of Sleep Disorders Research Articles

Efficacy of Poria Cocos Extract on Sleep Quality Enhancement: A Clinical Perspective with Implications for Functional Foods.

Since the outbreak of the pandemic started, an increase in the number of sleep disorders, including insomnia and poor sleep quality, has been seen. The pattern will probably continue. This study focuses on the preparation and clinical testing of Poria cocos extract in treating suboptimal sleep quality. The optimal extraction method utilized a 75% ethanol concentration, and the clinical investigation involved subjects with defined poor sleep taking 800 mg of the extract nightly, assessed using the Sleep Questionnaire and polysomnography. The non-parametric Wilcoxon signed-rank test was used for statistical analysis due to the non-normal distribution of the collected data. The study involved 21 insomnia sufferers with a mean age of 55 who were administered Poria cocos extracts. The findings of the study indicate a statistically significant rise in the overall duration of sleep (from 327.395 ± 43.2 min to 356.516 ± 63.21 min, p = 0.014). Additionally, there was a notable decrease in the level of arousal during sleep (from 76.316 ± 44.78 min to 47.989 ± 42.38 min, p = 0.009), and an improvement in the sleep severity index of the sleep questionnaire test. Poria cocos as a natural substance could improve quality of sleep, based on the findings. The study investigates Pachymic acid, a substance found in Poria cocos, as a potential indicator for the development of sleeping aids.

Propofol and sleep disorders

Sleep is an important physiological activity to maintain normal physiological functions of human body. With the acceleration of human life rhythm, the number of sleep disorders is increasing gradually at the same time. At present, many studies have shown that general anesthetics can cause loss of consciousness by acting on the sleep-wake circuit, and thus have a certain impact on human sleep in a short period of time. Propofol is one of the general anesthetics. Further observation and discussion of the effects of propofol on patients with sleep disorders will help to understand the effects of propofol on the prognosis and rehabilitation of patients. But studies on propofol and sleep disorders are rare. In this paper, by introducing the mechanism and regulating factors of sleep, the mechanism and influencing factors of sleep disorder, effect of propofol on sleep and its molecular targets leading to loss of consciousness are summarized. Also, the possible effects and underlying mechanisms of propofol on sleep disorders are summarized. Key words: Propofol; Anesthetics, general; Loss of consciousness; Sleep; Sleep disorder

The use and misuse of exogenous melatonin in the treatment of sleep disorders.

To explore the evidence for using exogenous melatonin in the treatment of sleep disorders, both primary and secondary, in children and adults. A number of recently published meta-analyses have shown that there is evidence for the efficacy of exogenously administered melatonin in a number of sleep disorders. However, melatonin is likely to be prescribed largely for reasons of perceived minimal side-effect profile and very low cost in situations in which high-quality evidence for its usefulness is not forthcoming. There is evidence for the efficacy of melatonin in the management of insomnia and some intrinsic disorders of circadian rhythm in adults and children as well as in reducing sleep onset latency in jet-lag and shift work disorder in adults. Melatonin is used routinely in the treatment of rapid-eye movement sleep-behaviour disorder despite limited trial evidence. Increasingly, dual melatonin receptor agonists are being trialled in a variety of sleep disorders. Long-term adverse effects are currently not fully identified.

Sleep disorders as primary and secondary factors in relation with daily functioning in medical students

BACKGROUNDCollege students experience various types of sleep disorders that impact daily functioning. Previous studies have focused on the effect of one sleep disorder.OBJECTIVEExamine factors that might relate to several sleep disorders and the impacts of sleep disorders on the daily functioning in medical students.DESIGNCross-sectional study.SETTINGMedical college.SUBJECTS AND METHODSA random sample of medical students from a public university was invited to participate in a cross-sectional study using the structured SLEEP-50 self-reported questionnaire. The sleep disorders covered by the questionnaire were insomnia, sleep apnea, restless legs syndrome, sleep walking, circadian rhythm sleep disorder, nightmares, narcolepsy, and factors impacting sleep, effects of sleep complaints on daily functioning, and sleeping duration.MAIN OUTCOME MEASURESleep duration, sleep disordersRESULTSOf 317 participants, 165 (50.2%) reported having less than 7 hours sleep and apart from hypersomnia, had various kinds of sleep disorders. Various factors such as having no pleasure and entertainment, feeling sadness, alcohol drinking, amount of sleeping hours, smoking, age, a noisy or light bedroom, and substance abuse were related to different sleep disorders. Moreover, students with sleep disorders felt tired arising, felt sleepy during the day, were easily irritated, had difficulty in concentration, had concerns about amount of sleep, and slept badly at college.CONCLUSIONSInsufficient sleep is a common issue in medical students and a number of sleep disorders were found. The results suggest that sleep disorders could have negative impacts on the daily functioning of students.LIMITATIONSThe study findings may not be generalizable because sociocultural characteristics of the sample may differ from the general population.

Current Concepts in the Diagnosis and Treatment of Sleep Disorders in the Elderly.

Sleep disorders are a pervasive problem throughout all patient populations but represent an especially important health problem for the elderly. Alterations in sleep architecture that occur as a part of normal aging will contribute to sleep problems as we grow older. Other contributing factors-including comorbid medical conditions, changes in lifestyle and schedule, altered circadian rhythm, among a host of others-can have detrimental effects on the health of the elderly. Coupled with a number of sleep disorders that either emerge or exacerbate with age, the effects of poor sleep often result in an overall worsening of quality of life. Treatment options can be unique in this population and often more difficult due to the effects of normal aging, as well as polypharmacy and possible medication interactions. The following article will focus on the common sleep disorders that can besiege this population, symptoms to aid in diagnosis, and specific treatment options to help improve quality of life in the elderly.

Excessive fragmentary myoclonus: time of night and sleep stage distributions.

Excessive fragmentary myoclonus during sleep consists of high amounts of brief twitch-like movements occurring asynchronously and asymmetrically in different body areas and has been reported to occur in association with a number of sleep disorders. It was analyzed using a new technique of quantification, the fragmentary myoclonus index (FMI). The FMI exhibited high rates in all stages of sleep but with a somewhat lower frequency in slow wave sleep explaining, as well, a significantly lower rate in the first hour after onset compared to later hours. There was no evidence for greater sleep fragmentation or lighter sleep compared to a matched patient group in whom it had not been noted.