The Low Rank Approximation (LRA) and Unscented Transform (UT) are integrated to produce a new algorithm having the capability to decrease the time required for the uncertainty quantification during Loss of coolant accident (LOCA) in Pressurized Water Reactors (PWR). The LRA is an efficient technique used in reducing computational cost due to its ability to perform dimensionality reduction by revealing the active or important degrees of freedom and calculate the basis of the so-called active subspace basing on the Singular Value Decomposition (SVD). For further reduction in the computational time; the UT algorithm is also implemented to generate a set of sigma points, these sigma points are the representatives of the whole probability distribution (the UT is restricted to Gaussian distribution). The main safety parameter is the maximum cladding temperatures during the accident which are computed by ATHLET thermal-hydraulic code. The reactivity coefficients and the covariance matrix are calculated using the SCALE 6.2 code. The present calculation model has 14-dimensions, therefore the number of sigma points needed for the SVD/UT technique is 29, and can be minimized to 5 sigma points only if the LRA/UT is used where two singular values are sufficient to reproduce/span the space thanks to the strong correlations between the reactivity coefficients.