Number Of Pulmonary Tuberculosis Patients Research Articles

GAMBARAN TINGKAT PENGETAHUAN KELUARGA TENTANG PENYAKIT TUBERKULOSIS PARU DI WILAYAH KERJA PUSKESMAS SUKAMERINDU KOTA BENGKULU

The increasing number of pulmonary tuberculosis patients in Indonesia is caused by a lack of public knowledge about pulmonary tuberculosis so that there are still many people who behave unhealthy. In addition, the level of family knowledge has a major influence on the health status of the family and the tuberculosis patient itself and plays an important role in the success of the prevention and prevention program for pulmonary tuberculosis. In 2021 cases of pulmonary tuberculosis patients at the Bengkulu City health office were reported to be 352 in adult patients and 33 in pediatric patients. The low success rate of pulmonary tuberculosis treatment in the city of Bengkulu is the low level of knowledge of families and tuberculosis sufferers in carrying out independent health care on a regular basis. This type of research uses a quantitative descriptive method. The purpose of this study was to describe the level of family knowledge about pulmonary tuberculosis in the Sukamerindu Public Health Center, Bengkulu City. This type of research uses a quantitative descriptive method. The research population was 37 respondents. The sampling technique used was total sampling. The research instrument used a questionnaire. The results showed that the level of family knowledge about pulmonary tuberculosis was in the good category 5%, in the sufficient category 57% and 38% in the less category. To increase public knowledge, it is necessary to provide health education and counseling about pulmonary TB.

KONDISI FISIK RUMAH (JENIS DINDING, JENIS LANTAI, PENCAHAYAAN, KELEMBABAN, VENTILASI, SUHU, DAN KEPADATAN HUNIAN) MEMPENGARUHI KEJADIAN PENYAKIT TUBERKULOSIS DI WILAYAH KERJA PUSKESMAS KRIAN SIDOARJO TAHUN 2021

Pulmonary Tuberculosis is a direct infectious disease caused by TB bacteria (Mycobacterium tuberculosis). In the Krian Health Center Work Area, the number of pulmonary TB patients has increased every year. Based on the profile of the Krian Health Center, Tuberculosis data for the last 3 years in 2017 - 2019 has increased with a percentage of 15% - 56.5% of cases. The purpose of the study was to analyze the relationship between the physical condition of the house and the incidence of pulmonary tuberculosis (TB) in the working area of ​​the Krian Health Center in 2021. This type of research is analytic with a case control approach. Collecting data using observation sheets. The research variable is the physical condition of the house including the types of walls, floors, lighting, humidity, ventilation, temperature and density of residential dwellings with a total sample of 47 patients and 47 non-patients using purposive sampling method. The data were analyzed using the chi-square test to determine the relationship. The value of the test results from the chi square of X2 statistical test results obtained p value = 0.037, then Ha is rejected. It can be concluded that the respondent's house category is related to the incidence of pulmonary TB disease but the odd ratio calculation is obtained a value of 2,424 (CI: 1,047 – 5,611), so respondents who have a house category are quite at risk of pulmonary TB disease 2,424 times greater than respondents with a house category that is good. It is recommended for health workers to increase their role as motivators and counselors for the community in order to increase knowledge about the importance of the physical condition of houses that meet the requirements for health by scheduling periodic counseling about healthy homes.

Factors that affect on the Event of Lung TB in Jati Kudus Health Center

Pulmonary tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which can attackthe lungs and other organs. Pulmonary tuberculosis is still one of the world’s public health problems eventhough TB control efforts have been implemented in many countries since 1995. The target of the nationalpulmonary TB prevention program is eliminated in 2035 and Indonesia free from pulmonary TB in 2050.Purpose of Research, this is to find out the factors that influence the incidence of pulmonary tuberculosisin the Jati Health Center Area. This study uses secondary data taken from data from the Jati Health Centerand the analysis in this study uses the CHAID Exhaustive method. The results of this study indicate thatthe number of pulmonary tuberculosis patients with a positive smear suspicion when viewed from the typeof sufferers is mostly new cases as many as 216 people. Associated with the type of patient who came fortreatment at the Teak Health Center, all patients seeking treatment received a cure category of 99.6% whichis a new patient treatment category. So the factors that influence the incidence of pulmonary tuberculosis arethe type of patient and treatment results.

PEER GROUP SUPPORT DAN PEMANFAATAN HASIL PERTANIAN UNTUK PENCEGAHAN PENULARAN TUBERCULOSIS PARU PADA KELOMPOK BERESIKO

Background: Pulmonary tuberculosis is a problem that is relatively high in Indonesia. Pulmonary tuberculosis at the end of 2019 has increased significantly. East Java is one of the provinces with the highest number of pulmonary tuberculosis patients, and Jember Regency is in second place after Surabaya for the number of sufferers. Objective: Increase knowledge of groups at risk of contracting pulmonary tuberculosis with peer group support method and provide information about agricultural materials to increase body immunity not to be susceptible to contracting pulmonary tuberculosis. Methods: Empowering health cadres and giving health education using leaflets and interactive discussions. Results: The implementation of this activity includes the formation of cadres to care for Pulmonary Tuberculosis, mentoring health cadres to conduct health education using a peer group support approach, conducting health education about agricultural materials to increase body immunity. Conclusion: After carrying out these community service activities, it is hoped that the health cadres that have been formed can continue to assist in increasing the knowledge of the surrounding community so that they are not easily infected with pulmonary tuberculosis.

Application of ARIMA model in predicting the incidence of tuberculosis in China from 2018 to 2019

Objective: Autoregressive integrated moving average (ARIMA) model was used to predict the incidence of tuberculosis in China from 2018 to 2019, providing references for the prevention and control of pulmonary tuberculosis. Methods: The monthly incidence data of tuberculosis in China were collected from January 2005 to December 2017. R 3.4.4 software was used to establish the ARIMA model, based on the monthly incidence data of tuberculosis from January 2005 to June 2017. Both predicted and actual data from July to December 2017 were compared to verify the effectiveness of this model, and the number of tuberculosis cases in 2018-2019 also predicted. Results: From 2005 to 2017, a total of 13 022 675 cases of tuberculosis were reported, the number of pulmonary tuberculosis patients in 2017 was 33.68% lower than that in 2005, and the seasonal character was obvious, with the incidence in winter and spring was higher than that in other seasons. According to the incidence data from 2005 to 2017, we established the model of ARIMA (0,1,2)(0,1,0)(12). The relative error between the predicted and actual values of July to December 2017 fitted by the model ranged from 1.67% to 6.80%, and the predicted number of patients in 2018 and 2019 were 789 509 and 760 165 respectively. Conclusion: The ARIMA (0, 1, 2)(0, 1, 0)(12) model well predicted the incidence of tuberculosis, thus can be used for short-term prediction and dynamic analysis of tuberculosis in China, with good application value.

Oxidative stress and its impact on mitochondrial DNA in pulmonary tuberculosis patients- a pilot study

BackgroundPulmonary tuberculosis (PTB) remains a major cause of morbidity and mortality all around the world. Recent studies have pointed out increased oxidative stress and also DNA damage in peripheral blood in PTB. Till date, to the best of our knowledge, no study has so far been conducted to show the mitochondrial DNA (mtDNA) deletions mapping in PTB patients. Therefore we performed the present study with the aim to investigate oxidative stress parameters along with mtDNA damage in newly diagnosed untreated PTB patients. Material and methodsThis is a prospective study carried out in Mahatma Gandhi Institute of Medical Sciences, Sevagram,Wardha, Maharashtra during september 2017 to september 2018.Thirty newly diagnosed untreated PTB patients and thirty age matched healthy controls were enrolled in the present study. Analysis of Oxidative stress parameters such as nitric oxide (NO) and malondialdehyde (MDA) were done by calorimetric methods. Assessment of mitochondrial DNA damage was carried out by mtDNA deletions mapping using primer shift long range polymerase chain reaction technique. ResultsThere was significant increase in levels of oxidative stress parameters, nitric oxide and malondialdehyde, in PTB patients compared to controls (p < 0.01). Generally there are two common deletion sites of “13 bp direct repeats” (ACCTCCCTCACCA) in mtDNA. One at the junction sites from bp 8470 to 8482 bp and another from bp 13447 to 13460 bp which make mtDNA more prone for 4977bp deletion. Out of thirty cases of PTB, two cases showed mtDNA damage in the form of mtDNA deletion of 4977bp. There was no mtDNA deletion in any control which can be attributed to continuous generation of oxidative stress. ConclusionThis pilot study has been able to demonstrate that compared to controls, in newly diagnosed pulmonary tuberculosis patients some mtDNA damage did occur and was probably due to continuous generation of oxidative stress in tuberculous patients. However, sample size is too small to draw any conclusions but definitely a more comprehensive study, by recruiting more number of pulmonary tuberculosis patients is warranted to establish correlation between oxidative stress and mtDNA damage in PTB.

Sputum Collection and Disposal Perceptions and Practices Among Pulmonary Tuberculosis Patients from Northern India.

Even a single case of pulmonary Tuberculosis (TB) can infect many others. Hence, to ensure better control of the disease, it is imperative that all patients dispose their sputum safely. Outcomes of this study would highlight the gaps need to be bridged in order to curtail transmission of TB. To analyse and ascertain perceptions about the disease and determine the sputum collection and disposal practices followed by sputum-positive TB patients. In this cross-sectional study, 422 sputum-positive TB patients aged more than 15 years registered in the Tuberculosis Unit Ambala city from January 2012 - September 2012 formed the study population. After enrolment, at the end of one month, they were assessed for sputum collection and disposal practices by a trained person at their place of residences. Questionnaire was framed to collect relevant data. Safe sputum disposal was practised by 46.4% of the study subjects. More females than males disposed of sputum safely (70.4% vs. 29.6%), as did more subjects of low than middle socio-economic status (74.1% vs. 25.9%). 70.9% (n=66) of the subjects with a family history of TB practiced safe sputum disposal methods as compared to 39.5% (n=130) subjects without a family history of TB practiced the same. Similarly more literate than illiterate subjects (n=150, 57.5% vs. n=46, 28.6%) practiced safe sputum disposal methods. (p< 0.001). Regarding knowledge of causation of TB only 63% of the study subjects were in the view that this disease is caused by germs. The study demonstrated that a large number of pulmonary TB patients practiced unsafe sputum disposal. Unsafe sputum disposal was higher among males, illiterate patients and those belonging to the lower socio-economic group. Therefore, it is need of the hour to launch Information, Education and Communication (IEC) activities so as to improve the sputum disposal practices among tuberculosis patients.

Clinical evaluation of the cause of death in patients with active pulmonary tuberculosis

We made a clinical analysis of the cause of death of forty deceased patients with active pulmonary tuberculosis who were admitted to Kawasaki Medical School Hospital, Kawasaki Medical School Kawasaki Hospital, and Asahigaoka Hospital during the period from January 1996 to December 2001. The age of 40 deceased patients (29 males/11 females) ranged from 55 to 93 years old, and were mostly bedridden. Underlying diseases existed in all except one case, and they were respiratory diseases in 9 patients and non-respiratory diseases in 34 patients. Laboratory findings revealed poor nutritional conditions. The diagnosis of pulmonary tuberculosis was established within one month from the appearance of symptoms in over half of these patients because most of them were smear positive for Mycobacterium tuberculosis. None of the strains of Mycobacterium tuberculosis isolated from these patients were multidrug resistant for antituberculous drugs and only one strain was completely resistant for Rifampicin. Radiological findings of the tuberculosis were bilateral in 30 patients. Consolidation shadows without cavity were noted in 22 patients, and extension within the unilateral lung field was observed in 24 patients. Regarding the cause of death, advanced pulmonary tuberculosis was the cause in 17 patients and non-tuberculous diseases were the cause in 23 patients. There were 15 patients with bacterial superinfections such as bacterial pneumonia, 4 with malignancy, and 4 with other disease. The number of pulmonary tuberculosis patients in poor general and nutritional condition has been increasing with the aging of the Japanese population. Treatment for pulmonary tuberculosis has been successful in most cases, however, the number of the deaths unrelated to tuberculosis including those due to bacterial superinfection has been increasing. Therefore, treatment should be considered against resistant microoganisms such as MRSA.