Number Of Opacities Research Articles

The Value of PSMA-RADS Version 2.0 in the Assessment of Pulmonary Metastases in Patients With Prostate Cancer and the Improvement of Differential Diagnosis Efficiency by PSMA PET/CT Parameters.

The aim of this study was to investigate the application of PSMA-RADS version 2.0 in assessment of pulmonary metastases in patients with prostate cancer and whether PSMA PET/CT parameters provide incremental value. From October 2016 to July 2023, PC patients with pulmonary opacities (including pulmonary metastases, lung cancer, and pulmonary benign opacities) who underwent Al18F-PSMA-BCH PET/CT scans were retrospectively analyzed. CT imaging characteristics, including the longest diameter, density, smoothness, lobulation, pleural retraction, and vacuole sign, as well as PET parameters including SUVmax and tumor-to-background ratio, were measured and analyzed. Additionally, the pulmonary PSMA-RADS score for each patient was determined. Independent predictors of pulmonary metastases were identified through univariate analysis and multivariate logistic regression analysis, which were utilized to construct a parallel diagnostic test. The differential diagnostic performances were evaluated using receiver operating characteristic analysis. A total of 148 pulmonary opacities from 96 patients were retrospectively included. The number of pulmonary benign opacities, lung cancer, and pulmonary metastases were 48 (32.4%), 20 (13.5%), and 80 (54.1%), respectively. The number of opacities across different PSMA-RADS scores from 2 to 5 was 8 (5.4%), 88 (59.5%), 7 (4.7%), and 45 (30.4%). SUVmax and smooth edges were independent predictors of pulmonary metastases (both P < 0.05), and the AUC of the parallel test for these 2 parameters was 0.86 (95% confidence interval: 0.79, 0.94; P < 0.001). Furthermore, the diagnostic accuracy of the parallel test across PSMA-RADS score from 2 to 5 was 85.7%, 79.6%, 100%, and 92.9%, respectively. Al18F-PSMA-BCH PET/CT parameters were helpful in differentiating pulmonary metastases in PC patients and provided incremental value when integrated with PSMA-RADS version 2.0.

Allergy and vernal keratoconjunctivitis: Results of a 251 children cohort

AbstractThe aim of our study was to follow the evolution of phenotype for children with lattice corneal dystrophy type I and granular corneal dystrophy type I. Mean age was 8,84 ± 4,20 years and 17,78 ± 3,76 years respectively. Corneal parameters were analysed from Scheimpflug photographs: number of opacities, location, thickness, depth and percentage of corneal transparency. Peripheral opacities in LCDI children continued to increase when the number of central deposits tended to stagnate after a mean age of 12 ± 1 years. GCDI children presented a continuous increase in number of opacities. Our results show a phenotypic heterogeneity, especially in early ages, which can lead to misdiagnosis.

Changes of copper, iron, and zinc in the serum of patients with silicosis, silicotuberculosis, and active lung tuberculosis

The serum concentrations of copper, iron, and zinc in silicosis were investigated related to the X-ray stage of the disease (according to the I.L.O.-U/C 1971 pneumoconioses international classification), to the TB complication, and to the plasma proteins level. The determination of oligoelements and plasma proteins was performed in 15 subjects suspected of silicosis and in 141 silicotic patients, selected by three criteria: the type criterium (opacity size, p, q, r), category criterium (number of opacities, 1,2,3), and TB complication criterium. The doses of copper, iron, and zinc were also established in 28 active lung TB patients and in a control group. The increase of the copper values in blood serum was noticed, simultaneously with the progress of silicosis, the highest change being found in the subjects with silicotuberculosis and active TB. A decrease of serum iron was also recorded, parallel to the silicosis evolution, as well as a hypozincemia with no variations related to the stage of the silicosis. No correlations were found between the changes of the oligoelements and the changes of plasma proteins.

Occurrence of cystoid spaces in the lens.

IN PATIENTS over 40 years of age small, cystoid spaces may occur just beneath the anterior and posterior surfaces of the adult nucleus. These changes appear to some degree in approximately 10% of otherwise normal eyes. With the ophthalmoscope the spaces beneath the anterior surface of the adult nucleus are seen as small, oval to round, grayish opacities arranged in a more or less symmetric fashion with the long axis concentric to the visual axis (Fig. 1). These small lesions have a dull, grayish color, and their borders are somewhat lighter. With the ophthalmoscope it has not been possible to identify the opacities in the posterior portion of the lens. The number of opacities seen may vary markedly. In some cases there may be only one or two eccentrically placed cysts, whereas other cases may show innumerable small opacities arranged in the usual concentric formation. When the optical beam of