Number Of Nausea Research Articles

The effect of breathing exercises on chemotherapy-induced nausea and vomiting in autologous hematopoietic stem cell transplantation patients: A randomized controlled trial

PurposeThis research was conducted as a randomized controlled study to examine the effect of breathing exercises on managing chemotherapy-related nausea and vomiting in patients who underwent autologous hematopoietic stem cell transplantation. MethodsA randomized controlled trial design was used, including an intervention group doing breathing exercises and a control group receiving standard care for chemotherapy-induced nausea and vomiting. The sample was selected from patients hospitalized in the bone marrow transplantation unit. A total of 70 autologous hematopoietic stem cell transplantation patients (35 intervention and 35 control participants).Several variables were evaluated, including the frequence and degree of nausea and vomiting, the patient's nutritional status, and the need for antiemetics. Data were analyzed and interpreted using Mann Whitney U, Pearson chi-square test, Independent t-test, Mann Whitney U, and multiple linear regression. ResultsIt was found that there was a negative relationship between the number of breathing exercises, the number of nausea and vomiting and the severity of nausea. As the number of breathing exercises increased, the number nausea and vomiting, and severity of nausea decreased significantly (p < 0.05). It was found that the use of antiemetics decreased in the intervention group. Furthermore, it was found that the intervention group had higher daily food consumption on the 3rd, 7th, and 9th days (p < 0.05). ConclusionBreathing exercises were a practical approach to managing chemotherapy-related nausea and vomiting.

Intervention effect analysis of alprazolam combined with biofeedback therapy on travel anxiety disorder in college students

BackgroundDue to economic pressure and environmental impact, college students often hesitate when planning their travels, resulting in anxiety to some extent. The conventional treatment method has relatively little effect on the treatment of college students’ travel anxiety disorder, so the study will use alprazolam combined with biofeedback therapy to intervene and treat college students’ travel anxiety disorder.Subjects and Methods 72 college students with travel anxiety disorder from a certain university were selected as the research subjects and divided into Group C and Group D according to the driver allocation method. Group C received traditional medication or psychological intervention, while Group D received a combination of alprazolam and biofeedback therapy. After the experiment, the data was processed using SPSS 20.0 statistical software.ResultsThe number of effective cases in Group D reached 30, with an effective rate of 95.38%, while Group C only had 81.54%, significantly lower than Group D; After treatment, the anxiety score of Group D was 29.1 ± 3.6, lower than Group C’s 39.0 ± 3.8, and significantly lower than the 41.7 ± 3.9 before the experiment; After treatment, the number of nausea and vomiting in Group D was 1, appetite loss was 3, and hair loss was 2 points, both lower than those in Group C. The incidence of adverse reactions after treatment was relatively low.ConclusionsThe combination of alprazolam and biofeedback therapy is effective in the intervention and treatment of travel anxiety disorder in college students.

The Effects of Acupressure in the Prevention of Nausea and Vomiting Related to Chemotherapy in Children: A Randomized Double-Blinded Placebo-Controlled Study

Background: Acupressure is known to be a nursing intervention used to prevent chemotherapy-induced nausea and vomiting in children. Methods: This study was conducted to evaluate and compare the effectiveness of manual and wristband acupressure in the prevention of chemotherapy-induced nausea and vomiting in children. This double-blinded and placebo-controlled study was conducted with 44 children aged between 5 and 18 years receiving chemotherapy in a university hospital's pediatric oncology clinic. Children were randomized into groups using a 2 × 2 factorial design: (a) The child who was given manual acupressure before the first chemotherapy was given placebo manual acupressure before the next chemotherapy; (b) the same child who was administered wristband acupressure before the first chemotherapy was administered placebo wristband acupressure before the next chemotherapy. After all interventions, the severity and number of episodes of nausea and vomiting and additional antiemetic needs in the children were monitored for 24 h. Results: In both groups, the severity and number of nausea and vomiting were lower according to their own placebo groups. Manual and wristband acupressure were effective in reducing the severity and number of nausea and vomiting, but manual acupressure was more effective in reducing the severity and number of nausea and vomiting in comparison to wristband acupressure (p < .05). No statistically significant difference was found between the groups regarding additional antiemetic drug use. Discussion: In this study, manual and wristband acupressure were determined to be effective in reducing the severity and number of nausea and vomiting related to chemotherapy.

The effect of breathing exercise on nausea, vomiting and functional status in breast cancer patients undergoing chemotherapy

ObjectiveThe aim of this study is to determine the effect of breathing exercise on nausea, vomiting, and functional status in breast cancer patients undergoing chemotherapy. MethodsThis randomized controlled trial was conducted with a total of 60 breast cancer patients in the ambulatory chemotherapy unit of a university hospital. The data were collected using Patient Information Form, Functional Living Index-Cancer (FLI-C), Visual Analog Scale, and Patient Diary. The patients were followed up for the first seven days. While the control group received routine nursing care until the posttest, the intervention group received breathing exercise for six days. On the seventh day, FLI-C was repeated for all the patients. ResultsIt was determined that the patients in the intervention group had less number of nausea, vomiting, and retching episodes after the breathing exercise (p < 0.05) and experienced lower severity of nausea (p < 0.05) compared to patients in the control group. ConclusionConsequently, it was determined that the breathing exercise reduced chemotherapy-induced nausea, vomiting and retching in breast cancer patients and affected positively functional status of patients.

Application of cognitive education in esophageal high resolution manometry examination

Objective To explore the effect of cognitive education and behavioral intervention in solid-state high resolution esophageal manometry (HRM) examination. Methods From April 2016 to June 2017, 60 patients with solid-state HRM in the gastrointestinal motility room at the First Affiliated Hospital of Jiaotong University were as the research object. The 60 patients were divided into control group and experimental group with 30 cases each by the method of random numbers. The conventional methods was used in control group to conduct informed counseling before the examination and the coordination guidance in the examination. The conventional methods and cognitive behavioral intervention was used in experimental group at the same time. The successful rate of intubation, the time used for the examination, discomfort symptoms during intubation, the patient′s satisfaction in the whole check process and self-evaluation of intubation pain experience in two groups of patients were compared. Results The time used in the experimental group examination was (28.50±8.75) min, and the control group was (33.13±5.49) min. The difference between the two groups was statistically significant (t=2.584, P=0.015). In the experimental group, the number of nausea, vomiting, and coughing in the intubation process was 11, 0, and 1, respectively, and the control group was 20, 6, and 7, respectively. The difference was statistically significant (χ2=5.406, 4.630, 5.192, all P<0.05). In the experimental group, the scores of the 2, 3, 4, 5, 7, 8, 10, 11, 12, and 13 items of the intubation pain experience self-evaluation in the examination process were (1.00±0.64), (1.37±0.85), (2.80±0.96), (1.50±0.51), (0.87±0.63), (0.77±0.50), (0.60±0.56), (1.07±0.25), (0.57±0.57), (1.50±0.63) points, and the 2, 3, 4, 5, 7, 8, 10, 11, 12 and 13 scores of the control group they were (1.50±0.51), (2.03±0.76), (3.50±0.82), (2.03±0.76), (1.20±0.61), (1.03±0.41), (0.83±0.53), (1.23±0.43), (0.87±0.57), (2.00±1.05) points, respectively. The difference was statistically significant (t=-4.130--2.140, all P<0.05). Conclusions HRM is an important test before the clinical application of a wide range of clinical applications for the detection of esophageal motility disorders and gastroesophageal reflux disease. The degree of patient cooperation with the operation directly affects the high-resolution esophageal manometry test results and self-experience. Medical staff can give patients cognitive education and behavioral intervention before examination, which can effectively reduce the symptoms and pain caused by intubation, improve patient compliance, shorten the time for examinations, improve work efficiency, and improve patient satisfaction. It is worth further promotion and application in clinical examination. Key words: Cognitive education; Behavioral intervention; High resolution esophageal pressure; Intubation discomfort; Satisfaction

To What Extend Aromatherapy with Peppermint Oil Effects on Chemotherapy Induced Nausea and Vomiting in Patient Diagnosed with Breast Cancer? A Randomized Controlled Trial

Background: Breast cancer is one of the most common malignancies in the world and in Iran. Prevalence of this disease in Iran 21.4% was reported. One of the main alternatives for treating breast cancer is chemotherapy which causes complications such as acute and delayed nausea and vomiting. The aim of this study was to determine the effect of aromatherapy with peppermint oil on nausea and vomiting induced by chemotherapy among breast cancer patients. Methods: This study was a randomized controlled trial on 100 women who suffering from Breast Cancer and receiving chemotherapy as outpatient's hospital care in Imam Khomeini. Before chemotherapy and after obtaining informed consent the patients with random sampling block were randomly allocated into intervention and control group. Intervention group received routine medications for controlling nausea and vomiting as well as aroma therapy with peppermint for five days. Meanwhile, the control group received only the routine medications. The data were gathered by using demographic and Rhodes Standard Questionnaire (about severity and number of nausea and vomiting). The results obtained from both groups were compared by using the SPSS version 11.5 software and descriptive and analytic statistics. Results: The results showed there were no statistical differences between two groups in some variables such as age, duration of cancer, history of alcohol use, history of nausea and vomiting (p>0.05). Use of aromatherapy with peppermint in acute phase lead to decreased of nausea and vomiting without any complications (p 0.05). Indeed more than half of samples stated that they are satisfied with aromatherapy and recommend it to others. Conclusions: Aromatherapy with peppermint in breast cancer patients could decrease nausea and vomiting in acute phase after chemotherapy. It is suggested that nurses use this aroma therapy as a complementary treatment, inexpensive and without complications for relieving the nausea and vomiting caused by chemotherapy.

Ondansetron rapidly dissolving film for the prophylactic treatment of radiation-induced nausea and vomiting-a pilot study.

The purpose of the present study was to investigate the efficacy of an ondansetron rapidly dissolving film (rdf) in the prophylaxis of radiation-induced nausea and vomiting (rinv). Rapidly dissolving film formulations facilitate drug delivery in circumstances in which swallowing the medication might be difficult for the patient. Patients undergoing palliative radiotherapy at risk for rinv were prescribed ondansetron rdf 8 mg twice daily while on treatment and were asked to complete a nausea and vomiting-specific daily diary, the Functional Living Index-Emesis (flie), and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-C15 Palliative (qlq-C15-pal). Patients were categorized as receiving primary or secondary prophylaxis based on whether they had already experienced emetic episodes. "Overall control" was defined as a maximum increase of 2 episodes of nausea or vomiting from baseline. "Acute phase" was defined as the days during radiation until the first day after radiation; "delayed phase" was defined as days 2-10 after radiation. The study accrued 30 patients. Rates of overall control for nausea and for vomiting during the acute phase in the primary prophylaxis group were 88% and 93% respectively; during the delayed phase, they were 73% and 75%. Rates of overall control for nausea and for vomiting during the acute phase in the secondary prophylaxis group were both 100%; during the delayed phase, they were 50%. The number of nausea and vomiting episodes was found to be significantly correlated with the flie and qlq-C15-pal questionnaires. Ondansetron rdf is effective for the prophylaxis of rinv.

Prévention des nausées et vomissements postopératoires : enquête sur les pratiques en chirurgie gynécologique auprès des membres du Club d’anesthésie réanimation en obstétrique

Objectives A prophylactic anti-emetic strategy should depend on the number of nausea and vomiting risk factors. This study was undertaken to evaluate the practices of postoperative nausea and vomiting (PONV) prevention practices among obstetrician-gynaecologists, anaesthetists. Study design A prospective, self-administered questionnaire survey was emailed to all Club d’Anesthésie Réanimation Obstétricale (Caro) members (French Obstetric and Gynaecology Anaesthetists’ Association). Methods The questionnaire had closed-ended questions to evaluate each Caro member's prophylactic anti-emetic practices. Questions concerned demographic datas, prophylactic anti-emetic drugs administered to the patients with or without well known risk factors for developing PONV, the existence of protocol to prevent PONV in their own department of anaesthesiology and their awareness of the existence of French Society of Anaesthesia and Intensive Care (Sfar) PONV prevention guidelines 2007. Results Of 115 questionnaires, 66 respondents (57%) returned the questionnaires. Most of the respondents (74%) worked in a university hospital. Forty-two percent practiced exclusively in obstetric-gynaecology department. Fifty-six percent were anaesthetists for more than 20 years. Eighty-five percent of the physicians were well-informed about the SFAR's PONV prevention guidelines. Thirty seven percent of respondents assessed Apfel score systematically for all their patients. The percentages, which didn’t calculate the probability of PONV with Apfel score or calculated only in cases of PONV history or travel sickness were 18% and 45% respectively. In cases of two or more risk factors, 63% used droperidol, dexamethasone and ondansetron in double or triple combinations. Conclusions Although most surveyed practitioners were well informed about the new guidelines concerning PONV prevention, 27% not follow these guidelines regarding the administration of anti-emetic drugs. The calculation of Apfel score in the preoperative period must be also strengthened.