In an effort to overcome the difficulty of real-time early warning via traditional infrared imaging technology caused by the complex working environment in coal mines, this paper proposes a mine early warning method based on uncooled infrared focal plane technology. The infrared thermal spectrogram of the detected object was visually displayed in a pseudo-color image with high resolution and high sensitivity, which can realize the real-time detection and early warning of personnel safety in modern mines. The multipoint compression correction algorithm based on human visual characteristics divided the response units of all acquisition units into gray intervals according to a threshold value, then the corresponding parameters were set in different intervals, and finally, each interval was compressed using a two-point correction algorithm. The volume of stored data was the sum of the calibration curve and the data from an encode table corrected by a MATLAB simulation, and the number of CPU cycles was run by a CCS 3.3 clock calculation algorithm. The results showed that when the temperature of the blackbody reached 115 °C, the nonuniformity before correction was 6.32%, and the nonuniformity after the multipoint correction of human eyes was 2.99%, which implied that the algorithm proposed in this paper had good denoising ability. The number of CPU cycles occupied by this algorithm was 18,257,363 cycles/frame with a frequency of 29.97 Hz. The sharpness of the compressed infrared images was obviously improved, and the uniformity was better. The method proposed in this paper can meet the need for modern mine personnel search and rescue, equipment supervision and dangerous area detection and other early warning requirements so as to achieve the goal of developing smart mines and ensuring safety in coal mine production.