AbstractBackgroundRemote monitoring (RM) of cardiac implantable electrical devices (CIEDs) can detect various events early. However, the diagnostic ability of CIEDs has not been sufficient, especially for lead failure. The first notification of lead failure was almost noise events, which were detected as arrhythmia by the CIED. A human must analyze the intracardiac electrogram to accurately detect lead failure. However, the number of arrhythmic events is too large for human analysis. Artificial intelligence (AI) seems to be helpful in the early and accurate detection of lead failure before human analysis.ObjectiveTo test whether a neural network can be trained to precisely identify noise events in the intracardiac electrogram of RM data.MethodsWe analyzed 21 918 RM data consisting of 12 925 and 1884 Medtronic and Boston Scientific data, respectively. Among these, 153 and 52 Medtronic and Boston Scientific data, respectively, were diagnosed as noise events by human analysis. In Medtronic, 306 events, including 153 noise events and randomly selected 153 out of 12 692 nonnoise events, were analyzed in a fiveāfold crossāvalidation with a convolutional neural network. The Boston Scientific data were analyzed similarly.ResultsThe precision rate, recall rate, F1 score, accuracy rate, and the area under the curve were 85.8 Ā± 4.0%, 91.6 Ā± 6.7%, 88.4 Ā± 2.0%, 88.0 Ā± 2.0%, and 0.958 Ā± 0.021 in Medtronic and 88.4 Ā± 12.8%, 81.0 Ā± 9.3%, 84.1 Ā± 8.3%, 84.2 Ā± 8.3% and 0.928 Ā± 0.041 in Boston Scientific. Fiveāfold crossāvalidation with a weighted loss function could increase the recall rate.ConclusionsAI can accurately detect noise events. AI analysis may be helpful for detecting lead failure events early and accurately.