The central Tibetan Plateau, particularly the Bangong–Nujiang suture zone, hosts abundant and complex Late Mesozoic geological records and world-class mineral resources. However, intense debate persists about the origin and tectonic setting of these geological records and mineral resources, which impedes a comprehensive understanding of regional Late Mesozoic tectonic evolution and mineralization. In this study, we investigated the petrochronology, geochemistry, and Sr-Nd-Hf isotopic characteristics of ∼120 Ma magmatic rocks in this region. We explored their petrogenesis and sources, and in conjunction with their spatiotemporal distribution and scale, we facilitated a first proposal that these magmatic rocks were derived from ∼120 Ma hotspot–subduction zone interaction and that world-class mineral deposits were formed in this geological setting. This study is the first to identify geological records of hotspot–subduction interaction in the central Tibetan Plateau and it has significant implications for gaining a deeper understanding of the closing processes of the Late Cretaceous Epoch in the Meso-Tethys Ocean. This study also highlights the substantial contribution of this hotspot–subduction zone interaction to the formation of world-class mineral deposits in the region, and thus has crucial significance for guiding mineral exploration in the central Tibetan Plateau.
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