The structure of nuclear matter at short internucleon distances is one of the poorly studied aspects of nuclear physics. At distances of the order of the nucleon radius, nuclear matter is represented by the pairs of correlated nucleons with relative momenta exceeding the Fermi momenta that emerge for a short time. Such structures, whose local density is comparable to the density of neutron stars, arise from fluctuations in the average nuclear density. One of the important characteristics of nucleon–nucleon correlations is their universality implying the independence of their properties from the nuclear mass number. Therefore, the peculiarities of these objects of nuclear structure reflect the properties of nuclear matter rather than specific nuclei. Information about the short-distance physics is extracted from the analysis of processes with high energy–momentum transfers. Until now, the property of universality has been observed in electron–nucleus collisions only for the breakup of nucleon pairs. In this paper we analyze the data on the cumulative production of pions by protons on a set of nuclear targets and for the first time have established the existence of universality of two-nucleon correlations in the production of π+ and π– mesons. We have obtained evidence for the involvement of three-nucleon correlations in the production of pions beyond the kinematics of their production in interactions with two-nucleon objects.