Novel Approach For Visualization Research Articles

A novel approach for visualization, monitoring, and control techniques for Scrum metric planning using the analytic hierarchy process

AbstractAlthough Scrum is one of the most preferred agile development frameworks that guide the development process, measuring sprint productivity is still challenging. In fact, it is hard to provide a continuous measurement during consecutive Scrum sprints, especially selecting the optimal metrics that fit better for real industrial applications. To bridge this gap, we conducted an industrial case study within the TÜBİTAK SAGE software development group to demonstrate the performance and applicability of a systematic selection process for fitting add‐on components using various scrum metrics tools. Next, we analyzed the combination of software developers' preferences of process metrics concerning their characteristics and their defense industry compatibility. Consequently, we assessed the metrics that might likely integrate into the Scrum development using the analytic hierarchy process. The results indicated that the Actionable Agile Add‐on scored the highest, followed by the Screenful Add‐on. Ultimately, this contemporary study presented a novel approach that has increased individuals' participation in metric planning, implementation, and monitoring, therefore moving towards more achievable software development goals.

A novel approach for visualization and localization of small amounts of DNA on swabs to improve DNA collection and recovery process.

In this report, a simple and practical procedure is proposed for DNA localization on a solid matrix e.g., a collection swab. The approach is straightforward and employs spectrum decomposition using a model DNA intercalator Ethidium Bromide (EtBr). The proposed approach can detect picograms of DNA in solution and nanograms of DNA on solid surfaces (swabs) without the need for PCR amplification. The proposed technology offers the possibility for developing an inexpensive, sensitive, rapid, and practical method for localizing and recovering DNA deposited on collection swabs during routine DNA screening. Improved detection of low DNA concentrations is needed and, if feasible, will allow for better decision making in clinical medicine, biological and environmental research, and human identification in forensic investigations.

Tracing molecular and structural changes upon mucolysis with N-acetyl cysteine in human airway mucus

The conducting airways of the human lungs are lined by mucus, which lubricates the lung epithelium and provides a first-line protection against airborne threats. As a novel approach for visualization of the human mucus microstructure, we applied confocal Raman microscopy as a label-free and chemically selective technique. We were successfully able to chemically resolve the pulmonary surfactant from the mucus matrix and show its spatial distribution, as well as to visualize the structural changes within the freeze–dried mucus mesh upon chemical mucolysis. Subsequently, we performed rheological measurements before and after mucolysis and correlated morphology and chemical structure of the mucus with its rheological characteristics. These results do not only enrich the knowledge about the mucus microstructure, but can also, significantly contribute to rational development of future lung therapeutics.

Diffraction Enhanced X-ray Imaging of the Distal Radius: A Novel Approach for Visualization of Trabecular Bone Architecture

In Canada, osteoporotic fractures result in direct health care costs that exceed CAD$1.3 billion annually [1]. Fractures are related to compromised bone strength, a parameter that reflects both density (quantity) and architecture (quality) [2]. The current clinical standard for bone assessment, dual energy x-ray absorptiometry, provides only a 2-dimensional areal measurement of density and no architectural information [3]; therefore, the development of improved methods for visualizing and quantifying of bone architecture remains an important goal with respect to improving detection and treatment of osteoporosis. Advances are currently being sought in the development of new technologies [3], such as high-resolution peripheral quantitative tomography [4], and through texture-based analysis of trabecular structure from radiographs [5]. In this pictorial essay, we explore the use of x-rayebased diffraction enhanced imaging (DEI) by using synchrotron radiation [6] as a novel means of visualizing the internal architecture of the human distal radius, a clinically significant fracture site. Imaging for this study was conducted at the Canadian Light Source (CLS) synchrotron during commissioning of the BioMedical Imaging and Therapy (BMIT) bending magnet beam line [7]. As such, our goal here is 2-fold: (1) establishment of proof-of-principle