The paper presents data on unknown localities and new species of flora of the Chechen Republic, which we discovered during expeditionary research in 2022-2023 on the territory of the Makazhoi semiarid basin. The study area belongs to arid ecosystems with unique species and coenotic diversity. Nearby there is a unique natural monument and tourist attraction - the alpine lake Kezenoy-Am. In recent years, the tourism industry has been actively developing here, which inevitably leads to anthropogenic transformation of the flora and increases the risk of losing the uniqueness, originality, and characteristic features of the flora and vegetation of mountain landscapes. For the first time, we provide information about the discovery of 11 new species, previously unknown for the republic, belonging to 9 genera and 8 families. In our research, we strive to emphasize the need for in-depth study and conservation of the biodiversity of these ecosystems for future generations.