The article deals with the practical philosophy of Immanuel Kant, its transformation in the modern ethics of responsibility and the significance of «risks and threats» for modern society. It is emphasized that in Ukraine, in particular, in the H.S. Skovoroda Institute of Philosophy of the National Academy of Sciences of Ukraine, a powerful historical-philosophical tradition of research in German classical philosophy has developed, the foundation of which is the philosophy of I. Kant. This trend gained a new development after the restoration of Ukraine's independence. Special attention was paid in the investigation to the study of Kant's moral philosophy, its important component – the categorical imperative. It is shown that Kant's practical philosophy became an important driver of the leading trends of modern philosophy in the world, which was manifested in the process of «rehabilitation of practical philosophy», which includes the philosophy of responsibility of H. Jonas, communicative philosophy and ethics of discourse. These trends prompted the search for new formulations of the categorical imperative. The relevance of Kant's practical philosophy is evident especially today, under the conditions of modern technological civilization, the destruction of the normative order in the world, and the crisis of moral guidelines. Kant's concept of the primacy of the practical (moral and ethical) mind over the theoretical, technical and instrumental mind opens up ways to solve the global problems of our time, especially in the conditions of crisis and war. Kant's anniversary coincides with a special period of Ukrainian history: the modernization of Ukrainian society, the restoration of national identity, and orientation towards universal values. This event acquires special significance in view of the Russian aggression against Ukraine. Distorting the enlightment, moral-ethical and universalistic direction of Kant's philosophy, Russian propaganda tries to use it for ideological and propaganda purposes. That is why events dedicated to Kant's anniversary are an important component in the fight against the Russian aggressor.