Normal Duct Tissues Research Articles

耳下腺多形腺腫被膜形成に関与する因子

From June 1984 to March 1991, 25 patients with benign parotid gland pleomorphic adenoma were treated surgically in my department of otolaryngology. Histological study was done to clarify the important factors participating in the formation of the capsule of benign parotid gland pleomorphic adenoma. In the tissues surrounding the capsule of the tumor, atrophy of acinal cells, lipoid degeneration, increase of the connective tissues around the lobules and dilatation of the interlobular ducts, which seemed to be due to compression by the tumor itself, were found. In the capsule wall and/or just outside it, normal duct tissues were seen and in constricted parts of the capsule, vessels were sometimes recognized. In some parts, the increased connective tissues around the lobules were combined with the tumor capsule. Small defects of the capsule were seen in a few cases of Seifert's type 2 tumor (stromal component rich type), and in all such cases newly formed cnnective tissue membranes were seen a little outside such parts. These findings suggest that the parotid gland tissue around the tumor participate in the formation of the tumor capsule.

Complete extirpation of thoracic duct; use in management of primary benign tumor producing spontaneous chylothorax.

• A patient whose symptoms had suggested the possibility of chronic appendicitis was found to have a chylothorax on the right side. Open thoracotomy revealed a tumor, cylindrical in form, involving the entire thoracic duct. The tumor was removed, with the duct contained in it, and the normal duct tissue at either end was ligated. Suggestions of interstitial edema in the upper abdominal area appeared after the operation but disappeared in about five days. In all other respects the patient did exceedingly well and is still well two years after the operation. The tumor was found to be a lymphangioma of the thoracic duct. This experience establishes the fact that the main thoracic duct can be ligated with impunity and that extensive portions of it can be excised without endangering the patient's life.