The crowning achievement of this paper is the proof that round spheres are the only complete, simply-connected surfaces embedded in \mathbb{R}^{3} with nonzero constant mean curvature. Fundamental to this proof are new results including the existence of intrinsic curvature and radius estimates for compact disks embedded in \mathbb{R}^{3} with nonzero constant mean curvature. We also prove curvature estimates for compact annuli embedded in \mathbb{R}^{3} with nonzero constant mean curvature and apply them to obtain deep results on the global geometry of complete surfaces of finite topology embedded in \mathbb{R}^{3} with constant mean curvature.
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