Multiple tornado events frequently occur in different parts of the world. A region that seems favorable for recurring multiple tornado events due to its geographical location and topography is the eastern sector of the Trans-Mexican Volcanic Belt. A notable multiple tornado event that occurred in this region is investigated. It consisted of five simultaneous tornadoes during the convergence of three air masses: a cold air mass displaced from the north with moderately high relative humidity and specific humidity, a comparatively warm air mass with moderate relative humidity from the southeast, and a hotter air mass with low relative humidity from the southwest. This situation generated a line of intense horizontal wind shear through which the five tornadoes occurred. Numerical simulations revealed three cyclonic vortices and other minor disturbances along the shear line. Vertical cross-sections show rising air in these disturbances suggesting a cyclonic character. The results indicate that the relatively warm mass from the southeast moves over the one associated with a cold front coming from the north, generating multiple cyclonic rotation zones. Experiments with Lagrangian particles revealed vertical movements in the cyclonic rotation zones implying that the maximum heights of the tornadoes varied between 1000 and 1500 m. Moisture flux convergence calculations display structures resembling Kelvin-Helmholtz instabilities. This research proposes a conceptual model where the convergence of masses induced by topography can lead to multiple tornado generation.