Non-pharmacological Therapies Research Articles

Patient knowledge about risk factors, achievement of target values and guideline adherent secondary prevention therapies 12 months after acute myocardial infarction.

The prospective GULLIVE-R study aimed to evaluate adherence to guideline recommended secondary prevention, physicians' and patients' estimation of cardiac risk, and patients' knowledge about target values of risk factors after acute myocardial infarction (AMI). We performed a prospective study enrolling patients 9-12 months after AMI. Guideline recommended secondary prevention therapies and physicians as well as patients' estimation about their risk, and patients' knowledge about target values were prospectively collected. Between 07/2019 and 06/2021 a total of 2509 outpatients were enrolled in 150 German centers 10 months after AMI. The mean age was 66 years, 26.4% were women, 45.3% had STEMI, 54.7% had NSTEMI, 93.6% had revascularization (84.0% PCI, 7.4% CABG, 1.8% both). Guideline recommended secondary drug therapies were prescribed in over 80% of patients, while only about 50% received all five recommended drugs (aspirin, P2Y12 inhibitors, statins, beta-blockers, RAAS inhibitors) and regular exercise was performed by only one third. About 90% of patients felt well informed about secondary prevention, but the correct target value for blood pressure was known in only 37.9% and for LDL-C in only 8.2%. Both, physicians and patients underestimated the objective risk for future AMIs as determined by the TIMI risk score for secondary prevention. There is still room for improvement in patient education and implementation of guideline recommended non-pharmacological and pharmacological secondary prevention therapies in patients in the chronic phase after AMI.

The Effects of a Nonpharmacological Intervention Practice for Older Adults with Mild Cognitive Impairment and Their Family Caregivers in China

ABSTRACT Mild cognitive impairment (MCI) marks a critical phase in the progression to dementia. In our study, social workers utilized the Multicomponent Nonpharmacological Intervention Approach (MCNIA) to aid MCI participants (N = 52) and their caregivers, dividing into intervention and control groups. The intervention group underwent an additional regimen of non-pharmacological therapies besides pharmacological treatment. Our findings highlighted that: 1) MCNIA significantly enhanced cognitive and daily living abilities in the intervention group; 2) Caregivers experienced reduced burdens and improved social support; 3) Correlation analyses involving biomarkers indicated that MCNIA was particularly effective in alleviating depression in those with slightly more severe cognitive impairment.

Recommendations of Clinical Practice Guidelines for the treatment of urinary incontinence in women: A methodological survey

Objective: This study described and analysed key recommendations from Clinical Practice Guidelines (CPGs) concerning urinary incontinence (UI) treatment in women. Materials and methods: We carried out searches in the following databases: MEDLINE, EMBASE, Web of Science, Virtual Health Library, among others. The reviewers, in duplicate and independently, selected the documents and extracted the data. The quality assessment of the guidelines was carried out, in triplicate, using the Appraisal of Guidelines REsearch and Evaluation (AGREE II) instrument. Results: Six CPGs were selected for analysis. Pelvic Floor Muscle Training (PFMT) is the primary treatment for UI, with adjunctive therapies (biofeedback, vaginal cones, dynamic lumbopelvic stabilisation, and electrical stimulation) recommended alongside PFMT. Discrepancies among CPG were noted in recommendations for drug treatments and invasive procedures, suggesting the need for individualised approaches. When conservative non-pharmacological treatments failed, drugs are recommended. Mid-urethral slings were endorsed, with alternatives like colposuspension or autologous rectus fascial slings considered when mid-urethral slings were unsuitable. Botulinum toxin type A was suggested for urge UI patients unresponsive to conservative therapy. Conclusion: UI treatment must prioritise the conservative non-pharmacological therapies and progressing to invasive options, as necessary. These evidence-based findings aim to guide patients, healthcare professionals, and policy managers in effectively managing UI. Level of evidence: Not applicable

Outcome of Honey and Ghee Dressing as Compared to Regular Dressing Materials: A Comparative Study

Background: Ghee and honey has been advocated and used as dressing for infected wounds by Sushruta (600BC). The gratifying results observed with the dressing have prompted this study which aims to establish its efficacy in chronic infected wounds over one year period A standardised ghee and honey dressing was used to treat: chronic post- operative wounds and infected per op wounds, Honey and ghee dressing markedly reduces the foul odour and discharge, significantly improving the quality of life. The study will tell us comparative result of honey and ghee dressing as compared to expensive vacuum dressing and the regular dressing materials. Innumerable Randomised Control Trials (RCTs) reported on honey dressing for infected wounds, there is substantial evidence that ghee and honey dressing has at least comparable results to other modes of treatment. The easy availability and low cost of this treatment makes it significant in developing countries. Specially in rural population, Required permission has been from the HOD of orthopaedics. Material and Methods: Total 20 patients with compound fracture and chronic infected wound, were studied during the period of March 2023 to June 2023 at BVP RMC Loni, Maharashtra. Honey and ghee were taken from a fresh sealed box in 50:50 portion according to size of wound and mixed well then it was applied on the wound directly and covered with gauge and, the dressing was changed is cleaned with sterile normal saline as compared to normal dressing materials ie betadin, povidon iodine ointment, spirit. All Patients data was collected and compiled in Microsoft excel and were statistically analysed using appropriate statistical test using SPSS software. Results: Majority patient were males. Mean duration of wound healing among honey and ghee dressing was 15.3 and of regular dressing was 8.9 days. Conclusion: Honey is one alternative solution that can be used for non-pharmacological therapy. Honey can be used as a topical dressing .........

Nonpharmacological intervention therapies for dementia: potential break-even intervention price and savings for selected risk factors in the European healthcare system

BackgroundNew effective treatments for dementia are lacking, and early prevention focusing on risk factors of dementia is important. Non-pharmacological intervention therapies aimed at these factors may provide a valuable tool for reducing the incidence of dementia. This study focused on the development of a mathematical model to predict the number of individuals with neurodegenerative diseases, specifically Alzheimer’s disease, Parkinson’s disease, vascular dementia, and amyotrophic lateral sclerosis. Scenarios for non-pharmacological intervention therapies based on risk factor reduction were also assessed. The estimated total costs and potential cost savings from societal were included.MethodsBased on demographic and financial data from the EU, a mathematical model was developed to predict the prevalence and resulting care costs of neurodegenerative diseases in the population. Each disease (Alzheimer’s disease, Parkinson’s disease, vascular dementia, and amyotrophic lateral sclerosis) used parameters that included prevalence, incidence, and death risk ratio, and the simulation is related to the age of the cohort and the disease stage.ResultsA replicable simulation for predicting the prevalence and resulting cost of care for neurodegenerative diseases in the population exhibited an increase in treatment costs from 267 billion EUR in 2021 to 528 billion EUR by 2050 in the EU alone. Scenarios related to the reduction of the prevalence of dementia by up to 20% per decade led to total discounted treatment cost savings of up to 558 billion EUR.ConclusionThe model indicates the magnitude of the financial burden placed on EU healthcare systems due to the growth in the population prevalence of neurodegenerative diseases in the coming decades. Lifestyle interventions based on reducing the most common risk factors could serve as a prevention strategy to reduce the incidence of dementia with substantial cost-savings potential. These findings could support the implementation of public health approaches throughout life to ultimately prevent premature mortality and promote a healthier and more active lifestyle in older individuals.

Non-pharmacological treatments for anticipatory nausea and vomiting during chemotherapy: a systematic review and meta-analysis of the Clinical Practice Guidelines for Antiemesis 2023.

Anticipatory chemotherapy-induced nausea and vomiting (CINV) is a conditioned response influenced by the severity and duration of previous emetic responses to chemotherapy. We aimed to evaluate the efficacy of non-pharmacologic interventions for anticipatory CINV among patients with cancer. We conducted a systematic search in databases, including PubMed, the Cochrane Library, CINAHL, and Ichushi-Web, from January 1, 1990, to December 31, 2020. Randomized controlled trials, non-randomized designs, observational studies, or case-control studies that utilized non-pharmacological therapies were included. The primary outcomes were anticipatory CINV, with an additional investigation into adverse events and the costs of therapies. The risk-of-bias for each study was assessed using the Cochrane risk-of-bias tool, and meta-analysis was performed using Revman 5.4 software. Of the 107 studies identified, six met the inclusion criteria. Three types of non-pharmacological treatments were identified: systematic desensitization (n = 2), hypnotherapy (n = 2), and yoga therapy (n = 2). Among them, systematic desensitization significantly improved anticipatory CINV as compared to that in the control group (nausea: risk ratio [RR] = 0.60, 95% confidence interval [CI] = 0.49-0.72, p < 0.00001; vomiting: RR = 0.54, 95% CI = 0.32-0.91, p = 0.02). However, heterogeneity in outcome measures precluded meta-analysis for hypnotherapy and yoga. Additionally, most selected studies had a high or unclear risk of bias, and adverse events were not consistently reported. Our findings suggest that systematic desensitization may effectively reduce anticipatory CINV. However, further research is warranted before implementation in clinical settings.

The Efficiency of Kinesiotherapy versus Physical Modalities on Pain and Other Common Complaints in Fibromyalgia

Due to its variety of signs and symptoms, there have been numerous attempts to treat fibromyalgia (FM), but a cure has yet to be established. The aim of this study was to evaluate the effects of a complex kinetic therapy program and a combined physical modality program on pain and other common symptoms of FM. Patients and methods: A total of 78 female patients were included in this study; 39 subjects underwent a kinesiotherapy (KT) intervention (combining aerobic and Pilates exercises), and 39 participated in a physical modality (PM) program (including electrotherapy (TENS and low-laser therapy) and thermotherapy). Results: Regarding the parameter of pain assessment, kinesiotherapy demonstrated its superiority both during the treatment period and in the evaluation 3 months after therapy cessation. Both in terms of patient-reported pain (inter-group comparisons: p = 0.000 at T3) and the examination of tender points (inter-group comparisons: p = 0.000 at T3), as well as the algometric assessment, pain was alleviated by the two forms of applied kinetic therapy. The observed functional impairment was statistically significantly influenced (p = 0.001) at the end of the kinetic program application, while for the perceived functional impairment, neither therapy proved superiority over the other at any point of evaluation (inter-group comparisons: p = 0.715 at T3). Regarding the influence of the emotional consequences implied by fibromyalgia, neither the forms of kinesiotherapy nor the chosen physical modalities proved superiority at any point of evaluation (HAQ anxiety inter-group comparisons: p = 0.000 at T3). In conclusion, even though kinesiotherapy had superior influences on fibromyalgia pain in the studied group, the current research lends credence to the significance of non-pharmacological therapy in managing fibromyalgia. Participants demonstrated positive advancements in subjective and objective pain assessments, as well as improvements in functional and emotional well-being.

PENGARUH KOMBINASI TERAPI COUNTERPRESSURE DENGAN BIRTH BALL TERHADAP PENURUNAN NYERI PERSALINAN KALA I FASE AKTIF DI KLINIK CITRA MARENDAL

Background: Childbirth is the birth of the baby, placenta, and amniotic membranes from the uterus to the outside world. During labor, it can cause trauma to the mother because of the pain experienced. Some mothers are even traumatized to get pregnant and give birth again because they are afraid they will experience the same pain, especially for mothers who have given birth for the first time. Nonpharmacological therapy to reduce pain can be done counterpressure with a combination of birth balls. Objective: To determine the effect of a combination of counter pressure therapy with a birth ball on reducing active phase I labor pain. Method: This research used a quasi experiment with a two group only post test design. The population in this study were all mothers giving birth at the Citra Marendal clinic with a total sample of 36 people, each group consisting of 18 people. The instruments used were Numeric Rating Scale sheets and observations, with the Mann-Whitney Test hypothesis test. Conclusion: There is an effect of a combination of counter pressure therapy with a birth ball on reducing active phase I labor pain at the Citra Marendal Delitua Clinic with a p value = 0.001 &lt;0.05. Suggestion: For the future, it is hoped that they can develop research by examining various complementary methods that can reduce labor pain such as: the effectiveness of music therapy, aroma therapy, back massage, gym ball/birth ball techniques, relaxation techniques, remembrance, guided imagery.

Views of Hong Kong Chinese medicine practitioners on the application of the “Chinese Medicine Anti-epidemic Plans” prepared by the Chinese medicine expert group of central authorities: a focus group study

BackgroundDrawing on the extensive utilization of traditional Chinese medicine (TCM) to combat COVID-19 in Mainland China, experts designed a series of TCM anti-epidemic strategies. This study aims to understand Hong Kong CM practitioners’ application of and opinions on the “Chinese Medicine Anti-epidemic Plans.”MethodsOnline focus group interviews were conducted, and purposive sampling was employed to invite 22 CM practitioners to voluntarily participate in three interview sessions. The interviews were audio recorded, then transcribed verbatim. The transcripts were analyzed using template analysis.ResultsThree themes were derived: (1) facilitators of the “Chinese Medicine Anti-epidemic Plans,” (2) barriers of the “Chinese Medicine Anti-epidemic Plans,” and (3) expectations on improving the “Chinese Medicine Anti-epidemic Plans.” The participants could obtain relevant information from various sources, which highlights the value of the plans for TCM medicinal cuisine and non-pharmacologic therapies and guiding junior CM practitioners, supplementing Western medicine interventions, and managing Chinese herb reserves in clinics. However, the barriers included the lack of a specialized platform for timely information release, defective plan content, limited reference value to experienced CM practitioners, and lack of applicability to Hong Kong. The expectations of the CM practitioners for improving the plans were identified based on the barriers.ConclusionsTo enhance the implementation of the anti-epidemic plans, CM practitioners in Hong Kong expect to utilize a specific CM platform and refine the plans to ensure that they are realistic, focused, comprehensive, and tailored to the local context.

Pengaruh Endorphine Massage Terhadap Kualitas Tidur Ibu Hamil Usia Kehamilan 37- 40 Minggu

The decrease sleep duration during pregnancy increases in the third trimester. Giving non-pharmacological therapies that can be done to help improve sleep quality is to do an endorphine massage. The aim of this study was to determine the effect of endorphine massage on the sleep quality of pregnant women 37-40 weeks in the Working Area of the Mojo Health Center, Kediri Regency. The method of this research is Pre-Experiment with One Group Pretest-Posttest Design without a control group, using a total sampling technique with a total sample of 30 respondents. Endorphine massage intervention will be carried out 2 times in a row with the duration of 15-20 minutes each session. Data collection used the questionnaire PSQI, analysis used Mc Nemar test obtained P-Value 1 &gt; 0.05, it can be concluded that statistically, there is no effect of endorphine massage on the sleep quality of pregnant women 37-40 weeks in the Working Area of the Mojo Health Center, Kediri Regency. Poor sleep quality in pregnant women due to frequent awakening from sleep. This makes it difficult for pregnant women to achieve deep sleep. So it is necessary to do endorphine massage regularly by paying attention to disturbing factors, so that pregnant women can experience better quality sleep.

Auricular Therapy for Migraine.

Migraine brings hours or even days of disability, affecting 15% of the US population and one billion people worldwide. Migraine treatments have improved over the years and there is now a range of non-pharmacologic therapies that can be administered as monotherapy, combined with pharmacologic therapy or combined with other non-pharmacologic therapies to give greater options for those who do not tolerate, do not respond to, or who wish to reduce or avoid pharmacologic treatments. We conducted a review of the literature on auricular therapy as acute or preventive treatment for migraine, searching the databases of MEDLINE and ClinicalTrials.gov from 2013 to 2023. A total of 43 articles contained at least one search term, with three studies specific to acute or prevention of migraine (one for acute only, one for prevention only and one for both acute and prevention). The population was limited to, adults with migraine ages 18 or older, with the administration of auricular therapy as the intervention. While there have been studies on the use of auricular therapy for pain on two specific standardized auricular therapies, Battlefield Acupuncture (BFA) and National Acupuncture Detoxification Association (NADA), neither of these protocols were utilized in any of the studies specific to migraine management. Each of the three studies used different techniques, with one using acupuncture needles and five specific points and two using semi-permanent needles (remained in for a few days) that were placed in areas that showed high activity. Each of these studies showed auricular therapy to have benefit for the management of migraine. However, the authors of each of the studies recommended further studies. Auricular therapy may be a helpful adjunctive treatment to abort a current migraine attack or aid in reducing the frequency or severity of migraine attacks.

Navigating the complexity of pain in psoriatic arthritis and axial spondyloarthritis.

Pain is the most common and often most troublesome feature of chronic autoimmune diseases such as psoriatic arthritis (PsA) and axial spondyloarthritis (AxSpA). A predominant concept is that the main source of pain is from disease-induced tissue inflammation and structural damage, activating peripheral nerve fibers which relay to the central nervous system. This mechanism is nociceptive pain and the presumption has been that controlling inflammation will be sufficient to reduce this form of pain. However, despite control of inflammation, patients may still have significant residual pain. We are learning that there are additional pain mechanisms, neuropathic and nociplastic, that are often operative in patients with rheumatologic conditions, that can significantly influence pain experience, quantitation of disease activity, and may benefit from therapeutic approaches distinct from immunotherapy. Neuropathic pain arises from diseased or damaged nerve tissue and nociplastic pain reflects sensitization of the central nervous system due to multiple genetic, neurobiologic, neural network dysregulation, and psychosocial factors. Pain arising from these mechanisms influence assessment of disease activity and thus needs to be factored into decision-making about immunotherapy efficacy. This review addresses the importance of accurately assessing the complex mechanisms of pain experience in patients with PsA and AxSpA to more appropriately manage immunomodulatory, neuromodulatory, and nonpharmacologic therapies.

Children And Adolescents With Irritable Bowel Syndrome: Treatment And Management.

Irritable bowel syndrome (IBS) is a disorder that causes stomach pain in children and adolescents. It may also impact one's quality of life. IBS is linked to gastrointestinal issues such as diarrhoea and constipation. Despite the identification of several potential pathophysiological pathways, the aetiology of IBS remained unknown. The aim of this paper is to discuss the diagnosis, pathogenesis, case studies and treatment of Irritable bowel syndrome in children and adolescents. This systematic review covered relevant papers from the previous ten years that were accessible in Science Direct, Elsevier, NCBI, and Web of Science related to the pathophysiology and function of pharmacological drugs such as antidepressants, antispasmodics, prokinetics, and antibiotics in children with irritable bowel syndrome. Only a few prospective therapy techniques have been investigated in children, and even fewer of those have been demonstrated to be effective. This article presents case studies including 50-59 children, which demonstrate a favourable acceptable impact that is more effective than a placebo in terms of reducing symptoms and improving the overall quality of life in children who have irritable bowel syndrome. Furthermore, the majority of the pathophysiological explanations and treatment options discussed are based on adult studies. These major issues arose when treating paediatric IBS, and they must be addressed in order to properly treat children with IBS. Trials that focus on many combinations of pharmacological and non-pharmacological therapies seem to be more helpful. In recent years, a number of systematic reviews have been conducted to evaluate the efficacy of medication treatments in children for IBS; however, the dependability of these systematic reviews needs to be further investigated owing to the various experimental designs and levels of evidence used. This article highlights paediatric therapy options, including pharmaceutical medications such as antidepressants, antispasmodics, prokinetics, and antibiotics. The goal is to alleviate IBS symptoms while also enhancing the quality of life for children with this illness.

ANALISIS PENURUNAN RASA MUAL DAN MUTAH PADA IBU HAMIL DENGAN PENGGUNAAN INHALASI AROMA THERAPI LEMON DI SALAH SATU PUSKESMAS KABUPATEN BANDUNG

Pregnancy is a natural event that occurs in women. The average incidence of nausea and vomiting in 2019 was 67.9%. Where this incidence occurs in primigravida and multigravida pregnant women. Nausea and vomiting in medical parlance is called emesis. Emesis is a state of nausea that is sometimes accompanied by vomiting with a frequency of less than 5 times. Nausea and vomiting are caused by an increase in the HCG hormone. Nausea and vomiting can be overcome using pharmacological or non-pharmacological therapy, one of the non-pharmacological therapies is lemon aromatherapy. This study uses a descriptive type of research with a one group pre-test and post-test approach. The population used was 30 pregnant women who experienced nausea and vomiting at the Ibun Health Center in Bandung Regency in 2022 and the sample used was total sampling. The variable in this study is inhalation of lemon aromatherapy to reduce nausea and vomiting in pregnant women. The data used are primary data by conducting interviews using the PUQE-24 questionnaire research instrument. Data analysis in this study used univariate analysis. The results showed that the frequency before being given inhalation of lemon aromatherapy was that most experienced mild nausea and vomiting as many as 20 people (66.7%) and after being given inhalation of lemon aromatherapy most experienced mild nausea and vomiting as many as 17 people (56.7%). The average decrease before being given is 6.37 and after being given is 4.37. So that there is a decrease before and after being given lemon aromatherapy inhalation. Suggestions for health workers to be able to provide education regarding the provision of this alternative therapy to pregnant women who carry out examinations to overcome the nausea and vomiting.

Application Of Pbm-Nir Therapy For Postpartum Mother's Discomfort In Maternity Nursing Care

Normal post partum is post partum discomfort due to uterine involution. Uterine involution in patients can cause pain in the uterus called afterpains. Discomfort caused by uterine involution requires various treatments to minimize the pain felt by the mother so that the mother's comfort can return. This can be overcome with non-pharmacological pain management strategies through innovative near infrared phototherapy or near infrared photobiomodulation (PBM NIR). The aim of this research is to analyze the results of implementing pain management with non-pharmacological PBM NIR therapy in normal post-partum mothers with post-partum discomfort nursing problems. Case study that focuses on the implementation of non-pharmacological nursing pain management techniques with PBM NIR therapy. The case study subjects were 3 normal post-partum maternal patients with the same problem, namely post-partum discomfort in the obstetrics room at the Muhammadiyah Hospital in Palembang. The results of the study showed that the implementation of non-pharmacological pain management techniques with PBM NIR therapy had an effective effect on dealing with post-partum discomfort with complaints of decreased discomfort, decreased moaning, and strong uterine contractions. Implementation of pain management can improve the comfort status of normal postpartum mothers. This study makes an important contribution to understanding of the role of nonpharmacological techniques in postpartum pain management, as well as highlighting the importance of implementing innovative therapies for labor, as well as highlighting the importance of implementing innovative therapies to improve the quality of care in postpartum mothers.

Aromatherapy blended lemon and lavender has an effect on nausea and vomiting in first trimester pregnant women at PMB Entin Hartini

&lt;p&gt;&lt;strong&gt;&lt;em&gt;Introduction:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; Nausea and vomiting are common complaints in the first trimester of pregnancy. One treatment to reduce nausea and vomiting is non-pharmacological therapy by providing a mixture of lemon and lavender aromatherapy. In this study, there was only one group, namely the intervention group, which received blended lemon and lavender aromatherapy. Before carrying out the intervention, pregnant women in the first trimester are given a pre-test to find out how often pregnant women feel nauseous and vomit. Then the pregnant mother is taught how to use aromatherapy blended lemon and Lavender with Roll On which will be done in the morning and evening for 6 consecutive days. -continuously. Next, another post-test was carried out to determine the effectiveness of providing aromatherapy.&lt;/em&gt;&lt;/p&gt;&lt;p&gt;&lt;strong&gt;&lt;em&gt;Objectives:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; The aim of this study was to determine the effectiveness of giving a mixture of lemon and lavender aromatherapy against nausea and vomiting in first trimester pregnant women at PMB (Independent Midwife Practice) Entin Hartini, A.Md. Keb Mrebet District, Purbalingga Regency.&lt;/em&gt;&lt;/p&gt;&lt;p&gt;&lt;strong&gt;&lt;em&gt;Methods:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; The type of research used in this research is pre-experimental with a One Group Pre-Test and Post-Test design.&lt;/em&gt;&lt;/p&gt;&lt;p&gt;&lt;strong&gt;&lt;em&gt;Results:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; The Wilcoxon test results were obtained by Asymp. signature. 0.00 that there is an effect of giving a mixture of lemon and lavender aromatherapy in reducing nausea and vomiting (&lt;/em&gt;&lt;em&gt;𝜌&lt;/em&gt;&lt;em&gt;- value = 0.00).&lt;/em&gt;&lt;/p&gt;&lt;strong&gt;&lt;em&gt;Conclusions:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; There is effectiveness of giving a mixture of lemon and lavender aromatherapy for nausea and vomiting in first trimester pregnant women at PMB Entin Hartini, A.Md.Keb.&lt;/em&gt;

Correlation between depression, physical exercise and neurodegenerative diseases

Introduction: Depression is the most common mental disorder, affecting a significant percentage of the adult population. The disease is associated with many negative health consequences and is one of the leading causes of disability and inability to work worldwide. This neurological condition is commonly associated with neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD) and Huntington's disease (HD). In recent decades, advancements have uncovered certain pathophysiological and molecular mechanisms underlying these disorders. These revelations suggest that, although they exhibit unique characteristics, there are notable parallels in the neurobiological changes associated with major depressive disorder (MDD) and the neurodegenerative processes in Alzheimer's disease, Parkinson's disease, and Huntington's disease. In this article the relevance of non-pharmacological therapies in the management of neurodegenerative diseases have been rising. Almost absent from side effects, non-pharmacological alternatives, including physical exercise have shown promising benefits. Aim of the study: The study aims to evaluate the association between depression symptoms and neurodegenerative diseases. Moreover, we indicate sport as a way to preserve and improve cognitive function, and to maintain a proper quality of life. Material and methods: We conducted a review of scientific publications published in the years 1998-2024 in English and Polish in the PubMed and Google Scholar databases. We used keywords such as "depression", "neurodegeneration” and “physical exercise”. Conclusions: Depression has been demonstrated to be a risk factor for neurodegenerative diseases and suggested to be a possible prodrome for them. However, sport can alleviate behavioral symptoms in neurodevelopmental disorders, like anxiety, depression, indifference and sleep disruptions.

Application of mindfulness-based interventions – MBCT and MBSR – in depression treatment and relapse prevention

Introduction: Depression stands as a primary contributor to disability, prompting extensive exploration of treatment and prevention strategies. Recognizing the limitations of conventional approaches, the significance of effective non-pharmacological therapies, like psychotherapy, in managing mental health disorders is increasingly acknowledged. There's a growing interest in mindfulness-based interventions such as Mindfulness-Based Cognitive Therapy (MBCT) and Mindfulness-Based Stress Reduction (MBSR). These interventions, which prioritize present-moment awareness and acceptance, target depression's mechanisms, such as rumination, while cultivating coping strategies and resilience. Mindfulness, with its comprehensive approach and capacity for self-regulation, emerges as pivotal in addressing psychiatric conditions. This paper aims to provide a comprehensive evaluation of MBCT and MBSR's effectiveness in treating depression and preventing relapses. Description of the state of knowledge: MBCT and MBSR exhibit promising potential in effectively managing and preventing depression. Moreover, they alleviate anxiety, emotional exhaustion, stress and psychological distress, while fostering improved coping with rumination, memory disturbances and emotional regulation. Summary: Research indicates that incorporating MBCT and MBSR could offer a hopeful avenue for managing and alleviating the symptoms of depression and mental disorders, by addressing underlying factors which play a pivotal role in their development. To corroborate these encouraging results, additional randomized, large-scale, placebo-controlled trials are essential.

Application of mindfulness-based interventions – MBCT and MBSR – in depression treatment and relapse prevention

Introduction: Depression stands as a primary contributor to disability, prompting extensive exploration of treatment and prevention strategies. Recognizing the limitations of conventional approaches, the significance of effective non-pharmacological therapies, like psychotherapy, in managing mental health disorders is increasingly acknowledged. There's a growing interest in mindfulness-based interventions such as Mindfulness-Based Cognitive Therapy (MBCT) and Mindfulness-Based Stress Reduction (MBSR). These interventions, which prioritize present-moment awareness and acceptance, target depression's mechanisms, such as rumination, while cultivating coping strategies and resilience. Mindfulness, with its comprehensive approach and capacity for self-regulation, emerges as pivotal in addressing psychiatric conditions. This paper aims to provide a comprehensive evaluation of MBCT and MBSR's effectiveness in treating depression and preventing relapses. Description of the state of knowledge: MBCT and MBSR exhibit promising potential in effectively managing and preventing depression. Moreover, they alleviate anxiety, emotional exhaustion, stress and psychological distress, while fostering improved coping with rumination, memory disturbances and emotional regulation. Summary: Research indicates that incorporating MBCT and MBSR could offer a hopeful avenue for managing and alleviating the symptoms of depression and mental disorders, by addressing underlying factors which play a pivotal role in their development. To corroborate these encouraging results, additional randomized, large-scale, placebo-controlled trials are essential.

Interventions for pediatric asthma a literature review of efficacy and safety in pharmacological and non-pharmacological modalities

Asthma continues to be a major global health concern due to its related morbidity and healthcare utilization, especially in children. Pharmaceutical treatments are crucial for managing asthma, but non-pharmacological therapies are now increasingly recognized for their complimentary benefits in enhancing quality of life and lowering medication reliance. This review examines the many methods for managing asthma that involve both non-pharmacological and pharmacological techniques. The review underscores the significance of environmental triggers, including dust mites, pet dander, and mold, and shows practical strategies for mitigating allergy symptoms and adjusting living environments. It also covers how enhancing indoor air quality using smoke-free zones and HEPA air filters might lessen asthma attacks, particularly in kids who are exposed to secondhand smoke and urban air pollution. The objective is to maximize the care of asthma and reduce the worldwide prevalence of this chronic respiratory disorder by implementing comprehensive approaches that incorporate both non-pharmacological and pharmaceutical interventions.