This paper discusses the existence of positive radial symmetric solutions of the nonlinear biharmonic equation ▵2u=f(u,▵u) on an annular domain Ω in RN with the Navier boundary conditions u|∂Ω=0 and ▵u|∂Ω=0, where f:R+×R−→R+ is a continuous function. We present some some inequality conditions of f to obtain the existence results of positive radial symmetric solutions. These inequality conditions allow f(ξ,η) to have superlinear or sublinear growth on ξ,η as |(ξ,η)|→0 and ∞. Our discussion is mainly based on the fixed-point index theory in cones.