Nonanoic Acid Research Articles

White Bean and Weed Desiccation With Pelargonic Acid

Few studies have evaluated pelargonic acid for desiccating white bean and annual weeds. Five field experiments were conducted from 2021 to 2023 near Exeter and Ridgetown, Ontario, Canada to assess pelargonic acid applied alone or sequentially at different rates and several alternative herbicides for desiccating white bean and annual weeds. Pelargonic acid applied at 3400 g ai ha-1 desiccated white bean 88, 92, and 98% at 5, 8, and 14 days after application (DAA), respectively. Increasing the application rate, using sequential application, or adding 28% urea ammonium nitrate (UAN), did not improve white bean desiccation. Pelargonic acid applied at 3400 g ai ha-1 desiccated green pigweed 0, 2, and 1%; common ragweed 4, 3, and 3%; common lambsquarters 0, 0, and 0%; green foxtail 8, 12, and 15%; and barnyardgrass 5, 5, and 4% at 5, 8, and 14 DAA, respectively. Increasing the application rate, using sequential applications, or adding 28% UAN did not improve overall weed desiccation, except for green foxtail where desiccation was enhanced 14, 14, and 15% with pelargonic acid applied at 6800 g ai ha-1 at 5, 8, and 14 DAA, respectively and common ragweed where desiccation was increased 5% with pelargonic acid applied at 6800 g ai ha-1 at 8 DAA. At 14 DAA, green pigweed, common ragweed, common lambsquarters, green foxtail and barnyardgrass desiccation with carfentrazone-ethyl was 30, 6, 0, 11, and 7%; with ammonium salt of fatty acid was with 60, 12, 0, 59, and 36%; with flumioxazin was 54, 68, 31, 90, and 69%; with saflufenacil was 100, 96, 75, 37, and 55%; with tiafenacil was 100, 88, 5, 80, and 42%; with glufosinate was 100, 95, 100, 99, and 96%; and with diquat was 100, 99, 99, 99, and 96%, respectively. Dry bean desiccation with ammonium salt of fatty acid, glufosinate, carfentrazone-ethyl, flumioxazin, saflufenacil, tiafenacil, and diquat was 98-99% at 14 DAA. Among the desiccants evaluated, diquat and glufosinate were the most effective with 99% white bean desiccation and 95-100% desiccation of annual weeds at 14 DAA.

Comparing Alternative Non-Selective Herbicides in Oregon and New Mexico

Abstract Municipalities are considering alternatives to traditional herbicides for suppressing weeds and vegetation in areas frequented by the public. Two field experiments were conducted to test the efficacy of alternative non-selective herbicides: one in Corvallis, Oregon, on a mixed lawn of perennial ryegrass, annual bluegrass, and broadleaf weeds, and another experiment in Las Cruces, New Mexico, on a predominantly bermudagrass lawn with broadleaf weeds. The experimental objective was to quantify and compare the effects of repeated applications of ten non-selective herbicides to terminate a lawn with mixed vegetation. Applications were made every two weeks for four applications starting on 15 April 2022 in Corvallis and 26 May 2022 in Las Cruces. Data collected included the percent green cover over time calculated using an area under the percent green cover progress curve (AUPGCPC), the percent green cover at the conclusion of the experiment, and the change in monocot and dicot density over the course of the experiment. All treatments resulted in a lower AUPGCPC compared to water only except for mint oil + sodium lauryl sulfate + potassium sorbate. The only treatments with an average percent green cover less than 50% was a combination of ammoniated soap of fatty acids + maleic hydrazide (47% green cover) in Corvallis and pelargonic acid (38%) in Las Cruces, suggesting that more applications would be needed to terminate the lawn under similar circumstances. At the conclusion of the experiment, the water only plots averaged 90% and 93% green cover in Corvallis and Las Cruces, respectively. The change of monocot and dicot densities over the course of the experiment indicated that some of the products tested may be more sensitive to dicots, or in some cases monocots, suggesting a potential for future selective herbicide research in certain locations and climates.

Photooxidation of Nonanoic Acid by Molecular and Complex Environmental Photosensitizers.

Photochemical aging and photooxidation of atmospheric particles play a crucial role in both the chemical and physical processes occurring in the troposphere. In particular, the presence of organic chromophores within atmospheric aerosols can trigger photosensitized oxidation that drives the atmospheric processes in these interfaces. However, the light-induced oxidation of the surface of atmospheric aerosols, especially those enriched with organic components, remains poorly understood. Herein, we present a gravimetric and vibrational spectroscopy study aimed to investigate the photosensitized oxidation of nonanoic acid (NA), a model system of fatty acids within organic aerosols, in the presence of complex organic photosensitizers and molecular proxies. Specifically, this study shows a comparative analysis of the photosensitized reactions of thin films containing nonanoic acid and four different organic photosensitizers, namely marine dissolved organic matter (m-DOM) and humic acids (HA) as environmental photosensitizers, and 4-imidazolecarboxaldehyde (4IC) and 4-benzoylbenzoic acid (4BBA) as molecular proxies. All reactions show predominant photooxidation of nonanoic acid, with important differences in the rate and yield of product formation depending on the photosensitizer. Limited changes were observed in the organic photosensitizer itself. Results show that, among the photosensitizers examined, 4BBA is the most effective in photooxidizing nonanoic acid. Overall, this work underscores the role of chromophores in the photooxidation of organic thin films and the relevance of such reactions on the surface of aerosols in the marine environment.

Temporal analysis of non-targeted flavor component variation in green tea storage and rapid prediction of storage duration

The precise changes in the flavor quality of green tea before and after the optimal consumption period remain elusive. This study used HS-SPME-GC–MS to carefully examine the volatile compounds of new tea and multiple green tea samples stored for optimal taste periods and simultaneously detected changes in taste and color during tea infusion. Notably, 16 compounds with VIP > 1.5 were identified, highlighting their significance in the overall analysis profile. Among these components, nonanoic acid, octanoic acid and hexanal were identified as potential contributors to off-flavors and rancid oil flavors in tea after storage. The color of the tea broth becomes darker. Bitter flavor is associated with increased amino acid content. The PSO-SVM model showed excellent accuracy for predicting the storage duration of green tea. These findings provide critical theoretical understandings of green tea manufacturing and quality control.

Simultaneous Measurement of Gaseous HONO and NO2− in Solutions from Aqueous Nitrate Photolysis Mediated by Organics

Field studies suggest that NO3− photolysis may play a more significant role than previously thought. In this study, we concurrently measured HONO, NO2, and NO2− in situ to gain a deeper understanding of the photogenerated HONO transfer to air and to better constrain the rate constants of NO3− photolysis. The presence of fatty acids (e.g., nonanoic acid, NA), which are naturally present in the environment, significantly increases the production of photogenerated HONO and NO2. With an increase in oxygen percentage, the release rate of photoinduced HONO slowed, while the release rate of NO2 accelerated. The measured JNO3− value averaged 1.65 × 10−5 s−1, which is two orders of magnitude higher than values reported in similar systems. The HONO transfer rate from the solutions increased from 2.3 × 10−4 s−1 to 5.6 × 10−4 s−1 as the NA concentration increased from 0.1 to 20 mM. This can be attributed to the accumulation of NO2− induced by NA at the interface. Within this interfacial region, NO2− in the solutions becomes more prone to transfer into gaseous HONO, suggesting that photogenerated NO2− hosted in atmospheric droplets may serve as a temporary reservoir of atmospheric HONO without illumination, influencing the atmospheric oxidizing capacity in the region for hours. Therefore, simultaneous measurements of both gas and particle phase photoproducts are recommended to better constrain the rate constants of NO3− photolysis, thereby enhancing the accuracy of predicting the photochemical production of HONO in the atmosphere.

Development of hydro-distillation extraction and macroporous resin enrichment method for GC–MS chemical profiling of volatile components in the dried root of Gentiana dahurica Fisch

The dried root of Gentiana dahurica Fisch. has an intensive flavour, which suggests the presence of volatile compounds. Thus, this study aimed to develop an effective extraction method for GC–MS profiling of volatile compounds of G. dahurica. Hydro-distillation and subsequent resin enrichment (HDRE) was developed and applied to the analysis of G. dahurica in comparison with simultaneous distillation and extraction (SDE), and ultrasonic assisted dichloromethane extraction (uDCM). The major components were azulene (33.83%), 1-hexanoic acid (14.19%) and octanoic acid (11.39%) in the HDRE; octanoic acid (17.24%), nonanoic acid (13.29%) and 2,4-di-t-butylphenol (12.73%) in the SDE; and α-amyrin (25.05%), β-amyrin acetate (15.11%) and β-amyrone (4.61%) in the uDCM. Moreover, the HDRE extract was shown to have certain antimicrobial activity against four bacterial strains. Thus, the HDRE method is a promising sample preparation method for GC-MS chemical profiling of volatile components of the dried roots of medicinal plants.

Comparative Study of the Chemical Characterisation of Bioactive Compounds in Different Fractions of Ethanol Extract of Amaranthus Spinosus Leaves

In the evolution of pharmaceutical research, and to discover novel drugs, as well as therapeutic agents the exploration of plant-derived secondary metabolites offers a promising avenue. The current investigation has identified several phytochemicals in the various fractions of the sample being studied. Comparative study on the fractions showed certain phytocompounds were soluble in the solvents of fractionation. Compounds such as n-Hexadecenoic acid, Phthalic anhydride, Dodecanoic acid had affinity for both solvents, however, in varying concentrations as they were more abundant in the n-Hexane fraction. The result of the GCMS showed the presence of 12 compounds in the n-Hexane fraction, with the most abundant being cis-Vaccenic acid (40.39 %), n-Hexadecanoic acid (13.21 %), 9,12-Octadecadienoic acid (Z, Z)- (11.52 %), Octadecanoic acid (10.33 %), and Linoelaidic acid (9.84 %), which are reported to exhibit various biological activities. The FTIR analysis of this fraction further revealed functional groups such as Alcohol, Carboxylic acid, Alkene, Alkane, Aldehyde, Carbon dioxide, Nitrile, Allene, conjugated alkene, phenol, and Alkyl & Aryl Halides. GC-MS result of chloroform fraction further revealed the presence of 13 phytochemical compounds, of which the abundant phytochemical compounds are Linoelaidic acid (32.99 %), Z,Z-10,12-Hexadecadien-1-ol acetate (17.12 %), Nonanoic acid (14.81 %), and Cyclohexene, 4-pentyl-1-(4-propylcyclohexyl)- (12.08 %), while the FT-IR result showed the presence of sixteen (16) peaks, with functional groups such as Alcohols, phenols, thiol, thiocyanate, and δ-lactone. This study therefore infers that the pharmacological potential of the plant may be linked to the presence of the bioactive compounds in it as revealed by this study, however, recommended further study to identify the pharmacological activity of the other compounds with unknown activities, explore more pharmacological activities of the known compounds to solidify the claims on them further, and further carry out toxicity studies on the compounds to ascertain their safety.

Pelargonic acid’s interaction with the auxin transporter PIN1: A potential mechanism behind its phytotoxic effects on plant metabolism

Pelargonic acid (PA) is a saturated fatty acid commonly found in several organisms, that is known for its phytotoxic effect and its use as bioherbicide for sustainable weed management. Although PA is already commercialised as bioherbicide, its molecular targets and mode of action is unknown according to the Herbicide Resistance Action Committee. Therefore, the aim of this work was focusing on the way this natural active substance impacts the plant metabolism of the model species Arabidopsis thaliana. PA caused increase of secondary and adventitious roots, as well as torsion, loss of gravitropism and phytotoxic effects. Moreover, PA altered the cellular arrangement and the PIN proteins activity. Computational simulations revealed that the intermolecular interactions between PA and the polar auxin transporter protein PIN1 are very similar to those established between the natural auxin IAA and PIN1. However, under intracellular conditions, the PA-PIN1 binding is more energetically stable than the IAA-PIN1. These results suggest that PA could act as an auxin-mimics bioherbicide. The exogenous application of PA would be responsible for the alterations observed both at structural and ultrastructural levels, which would be caused by the alteration on the transport of auxins into the plant, inducing root inhibition and ultimately total stop of root growth.

Biofunctionality of a new vinegar rich in anthocyanin from red-fleshed Niedzwetzky's apple: An ornamental plant.

In recent years, red-fleshed apple has attracted a lot of attention due to its pleasant appearance, taste, and being a valuable source of anthocyanins. Generally, different types of this apple are known as ornamental apple plants that are rarely found in various regions around the world like New Zealand, Kazakhstan, Kyrgyzstan, Australia,China, and Turkey. This study focused on the accumulation and changes of the bioactive and aroma-related volatile components at different production stages of a red-fleshed apple vinegar. The aim of this study is to produce an anthocyanin- and vitamin C-rich vinegar (NAV) from red-fleshed Niedzwetzky's apple for the first time. According to the results, in this vinegar, it wasdetermined high concentrations of total phenolic content (904.8mg-GAE/mL), total flavonoid content (0.25mg-EGCE/mL), vitamin C content (3024.3mg-AAE/mL), and 1,1-diphenyl-2-picrylhydrazyl (8.33mmol-TE/mL), as well as FRAP (13.57mmol-ISE/mL), respectively. Moreover, total anthocyanin content value was found to be 6.46mg/g. One of the components that provide the specified functional effect in this vinegar is chlorogenic acid, which constitutes the main phenolic compound, and the other one is cyanidin-3-glucoside, which is the major anthocyanin in this vinegar. The main volatile components associated with the aroma of vinegar are -acetic acid, -phenylacetic acid (5067.7µg/100mL), -phenethyl alcohol (3096.1µg/100mL), and -nonanoic acid (2939.0µg/100mL) compounds. Consequently, it is recommended to expand the range of Niedzwetzky's apples in the production and consumption of food products such as functional vinegar. Thus, a new vinegar with high functional properties will be introduced to the worldwide food industry. PRACTICAL APPLICATION: In this study, vinegar was produced from the small and dark-red-flesh-colored fruits of Niedzwetzky's apple tree, which is known in a small part of the world and is generally used as an ornamental plant due to its red-pink flowers. It has been determined that the produced vinegar has high bioavailability due to the apples with red inner flesh and high anthocyanin content and has a desirable aromatic content. Thus, a food product with high functional quality and desirable aroma, accessible to consumers all over the world, has been produced from a little-known fruit.

Spectrophotometric determination of zinc in blood and food samples using an air-assisted rapid synergistic-cloud point extraction method based on deep eutectic solvents

At room temperature, an air-assisted rapid synergistic cloud point extraction (AA-RS-CPE) method based on deep eutectic solvent (DES) was presented to determine Zn (II) traces in various samples. Nonanoic acid and L-menthol formed the synergistic reagent (DES) in a 2:1 mole ratio to reduce both time and cloud point temperature. Air cycles were used to maximize recovery and accelerate cloudy solution formation. The 4,4-dimethyl-2,6-dioxo-N-phenylcyclohexanecarbothioamide (DDPCCTA) and TritonX-100 were used as ligand and surfactant, respectively. The validation parameters, including the calibration curve linearity (0.2-900µgL-1), the limit of detection (LOD = 0.10µgL-1), the enhancement factor (EF = 120), and the preconcentration factor (PE = 100), were calculated. Additionally, the accuracy of the AA-RS-DES-CPE approach was proved by two certified reference materials (CRMs). Finally, the three greenness tools, the Blue Applicability Grade Index (BAGI), the Sample Preparation Metric of Sustainability (SPMS), and the Analytical Greenness Metric for Sample Preparation (AGREEprep), were used to evaluate the environmental sustainability values, health hazards, and applicability of this method. This approach was improved to be safer and more environmentally friendly than existing methods, with high application potential.

Characterization of the phytochemical constituents of methanol extract of <i>Spondias mombin</i> stem bark using high performance-liquid chromatography and gas chromatography mass spectroscopy

Spondias mombin is commonly used in traditional medicine to treat various ailments. This study was aimed to analyze the bioactive components of the methanol extract of S. mombin stem by High-performance liquid chromatography (HPLC) and Gas Chromatography-Mass Spectroscopy (GC-MS). Quantitative analysis of the extract showed that it had appreciable quantities of flavonoids, phenols, tannins, and proanthocyanidins. The HPLC fingerprints of the extract also revealed the presence of flavonoids, tannins, saponins, alkaloids, other phenols, and steroids. The most prevalent flavonoids were the flavones, and the alkaloids present in high concentrations were ribalinidine and linamarin. Some other phenolics, such as resveratrol, ellagic acid, chlorogenic and pyrogallic, were in high concentration. The GC-MS data detected bioactive compounds; notably among them were 9,12 -octadecadienoic acid (linoleic acid), n-hexadecanoic acid, and 9-oxo nonanoic acid. This study has established the presence of bioactive chemicals in the methanol extract of S. mombin stem bark, and these phytochemicals could be responsible for the plant’s medicinal properties.

Oleogel-based frying medium: influence of rice bran wax-canola oil oleogel on volatile profile in fried fish fillets

Oleogelation has proven to be a successful strategy for structuring oils. In recent years, the use of oleogels as a deep frying medium has gained popularity as an effective approach to minimise oil uptake and reduce the energy content of fried foods. This study was designed to evaluate an oleogel matrix consisting of rice bran wax and canola oil, prepared by oleogelation technique, as a deep frying medium. Two types of the oleogels (CRBO-3 with 3 g wax/100 g oil; CRBO-6 with 6 g wax/100 g oil) were formulated and these oleogels were tested as a frying medium for fish fillets. The prepared oleogels were compared with refined canola oil (CO, control) and evaluated for both the frying stability of the oils and the volatile profile of the fried fish fillets. In particular, differences were observed in the crystallization and melting profiles of oleogels before and after frying. Lower levels of total polar material, peroxide value and trans fatty acids contents were noticed in fish fillets fried in the oleogels. An increase in wax concentration had an impact on the volatile profile of fish fillets and lead significant increases in p-xylene, pentene-3-ol and nonanoic acid. In general, oleogel-based frying medium contributed to the formation of characteristic fish fillet including aroma notes of pineapple, balsamic and honey when compared to fish fried in refined canola oil. The findings suggest oleogels as an alternative frying medium for fish with reduced calorie value and improved aromatic quality.Graphical

Herbicide Stress Inducesbeetle Oviposition on Red Maples.

Flatheaded borers (FHB; Chrysobothris spp.), are woodboring-beetles that lay their eggs in the bark and cambium of deciduous trees in North America. Females often target stressed host-plants for oviposition. The reason why is unknown; however, stressed plants often suffer various induced phytochemical changes that may enhance larval infestation success depending on the stressor such as induced upregulation of defenses, reallocation of nutrients, and changes to volatile organic compound (VOC) emissions. To understand attraction of FHB to specific stress-induced changes, we analyzed phytochemical changes associated with stress treatments and attractiveness maple trees to FHB. Trees were stressed by: (1) chemical stress (pelargonic acid herbicide), (2) physical stress (physically removing leaves), and (3) physical stress (removing portions of bark near the root crown). After reflush of defoliated trees, bark tissues where FHB larvae feed were analyzed for nutritional changes (carbon and nitrogen), anti-nutritive changes (polyphenols and tannins) and emissions of foliar VOCs. At the end of the growing season, trees were assessed for FHB larval presence and oviposition attempts. There were more larvae and oviposition attempts on trees stressed by herbicide application. Compared to other treatments, herbicide-stressed trees had greater nitrogen and total polyphenol concentrations. Greater nitrogen may play a role in the fitness of feeding larvae, and the greater polyphenol concentration may stimulate female oviposition in the herbicide stressed trees. Females may be able to locate the herbicide-stressed trees by using volatile cues such as increases in limonene, α-farnesene, (E)-4,8-dimethyl-1,3,7-nonatriene (DMNT) and hexenyl acetate.

Analysis of metabolic spectrum characteristics of naturally and cultivated Ophiocordyceps sinensis based on non-targeted metabolomics

The analysis of the differences in metabolic profiles between naturally Ophiocordyceps sinensis (NO) and cultivated Ophiocordyceps sinensis (CO) is an essential process for the medicinal value mining of Ophiocordyceps sinensis. Non-targeted metabolomics was used to compare the differences in metabolite composition and abundance between NO and CO. Total metabolite composition found that NO is rich in organic acids and derivatives, and CO is rich in lipids and lipid-like molecules. HCA found that organooxygen compounds, cinchona alkaloid, and fatty acyls had different abundances in NO and CO. The variable importance in projection value and quantitative analysis of metabolites found that NO was rich in l-iditol, malate, linoleic acid, and oleic acid; CO is rich in sucrose, perseitol, hydroquinidine, nonanoic acid, 1-hydroxy-2-naphthoic acid, hymol-β-d-glucoside, and gly-his-lys. these compounds have the potential to be biomarkers of NO and CO. KEGG enrichment analysis showed that ascorbate and aldarate metabolism, carbon metabolism, pyrimidine metabolism, and fatty acid biosynthesis were the most different metabolic pathways between NO and CO. Therefore, the analysis of the characteristics of NO and CO metabolites has reference value for finding their different medicinal functions.

Perfluoroalkyl functionalized-Au nanoparticle sensor: Employing rate of spectrum shifting for highly selective and sensitive detection of per- and polyfluoroalkyl substances (PFASs) in aqueous environments

Per- and polyfluoroalkyl substances (PFASs) are emerging contaminants detected ubiquitously and have negative impacts on human health and ecosystem; thus, developing in-situ sensing technique is important to ensure safety. Herein, we report a novel colorimetric-based sensor with perfluoroalkyl receptor attached to citrate coated gold nanoparticles (Citrate-Au NPs) that can detect several PFASs including perfluorocarboxylates with different chain lengths (PFHxA, PFOA, PFNA, PFDA), perfluorooctanoic sulfonate (PFOS), and perfluorooctanoic phosphonate (PFOPA). The sensor detects PFASs utilizing fluorous interaction between PFASs and the perfluoroalkyl receptor of Citrate-Au NPs in a solution at a fixed salt concentration, inducing changes in nanoparticle dispersity and the solution color. The rate of spectrum shift was linearly dependent on PFASs concentrations. Citrate-Au NPs with size between 29 – 109 nm were synthesized by adjusting citrate/Au molar ratios, and 78 nm showed the best sensitivity to PFOA concentration (with level of detection of 4.96 µM). Citrate-Au NPs only interacted with PFASs with perfluoroalkyl length > 4 and not with non-fluorinated alkyl compound (nonanoic acid). The performance of Citrate-Au NP based sensor was strongly dependent on the chain length of the perfluoroalkyl group and the head functional group; higher sensitivity was observed with longer chain over shorter chain, and with sulfonate functional group over carboxylate and phosphonate. The sensor was tested using real water samples (i.e., tap water, filtered river water), and it was found that the sensor is capable of detecting PFASs in these conditions if calibrated with the corresponding water matrix. While further optimization is needed, this study demonstrated new capability of Citrate-Au NPs based sensor for detection of PFASs in water.

Green Liquid-Phase Microextraction Using Nonanoic Acid as a Novel Extractant for the Spectrophotometric Determination of Rhodamine B in Cosmetics

A new method for separating and concentrating Rhodamine B (RhB) in cosmetics has been developed using nonanoic acid liquid-phase microextraction (NA-LPmE) with spectrophotometric determination. Nonanoic acid is a novel and environmentally friendly extractant that was used as a single component in the isolation. In contrast, supramolecular solvents and deep eutectic solvents are often combined as a mixture. The method is simple, quick, accurate, and environmentally friendly. The appropriate parameters (the volume of NA, pH, sample volume, and matrix effects) were optimized and these conditions resulted in a suitable linear range (20.5–1000 µg L−1), low detection limit (6.2 µg L−1), and high pre-concentration factor (40). The NA-LPmE method successfully extracted and determined RhB in several cosmetics and employs a small volume of green solvent with spectrophotometric determination and rapid analysis. The combination of nonanoic acid and RhB was used for the first time.

Serum Medium-Chain Fatty Acids and the Risk of Incident Diabetes: Findings from the 4C Study.

Emerging studies have revealed associations between dietary medium-chain fatty acids (MCFAs) and glucose homeostasis. However, the relationship between serum MCFAs and the incidence of diabetes, and potential interactions with genetic predisposition, remains unclear in prospective cohort studies. To investigate associations and genetic susceptibility between serum MCFAs and diabetes risk. We investigated baseline serum MCFAs (n=5) in a nested case-control study comprising incident diabetes cases (n=1,707) and matched normoglycemic control subjects (n=1,707) from the China Cardiometabolic Disease and Cancer Cohort Study. Associations between MCFAs and type 2 diabetes mellitus (T2DM) were examined, both overall and stratified by diabetes genetic susceptibility. Genetic risk scores (GRS) were calculated based on 86 T2DM-associated genetic variants. In the fully adjusted conditional logistic regression model, serum octanoic acid and nonanoic acid exhibited inverse dose-response relationships with diabetes risk, showing odds ratios (95% confidence intervals) of 0.90 (0.82-0.98) and 0.84 (0.74-0.95), respectively. Subgroup analysis demonstrated that inverse associations between MCFAs and incident diabetes were more pronounced among individuals with physical inactivity (Pinteraction = 0.042, 0.034, and 0.037, for octanoic, nonanoic and decanoic acid, respectively). Moreover, inverse associations of octanoic acid with diabetes risk were notably enhanced among individuals with high genetic risk compared to those with low genetic risk. Significant interactions were observed between octanoic acid and GRS on T2DM risk (Pinteraction = 0.003). These findings provide evidence supporting inverse associations between serum MCFAs and T2DM risk, and reveal potential interplay between genetic susceptibility and circulating octanoic acid in modulating diabetes risk.

Effects of massive desiccation of olive waste residues on air quality

New industries are proliferating in the recovery of agri-food wastes, such as those involved in the revaluation of alperujo, generated in the production of olive oil. Despite the potential environmental benefits, their activity is not exempt from new forms of emissions, aggravated by the massification of waste treatments.This work reports a six-month field campaign carried out in an alperujo desiccation plant which can serve as a proxy for these emerging industries in the Mediterranean countries. The study focused on air quality parameters, covering criteria pollutants, metals and microbiological load of particulate matter and the characterization of volatile organic compounds (VOCs).The results show a slight contribution of the factory to the NOx levels in the surroundings (3.0–12.5 μg/m3). Statistically significant effects were not observed for ozone, CO, SO2, or PM10. Concerning the levels of metals, concentrations were low and calculated health risk indexes indicated safe conditions in the area. The most abundant elements were Na (6.5 × 102 ng/m3), K (4.0 × 102 ng/m3), Al (2.7 × 102 ng/m3), Zn (2.1 × 102 ng/m3), Ca (2.16 × 102 ng/m3), Fe (3.6 × 101 ng/m3) and Mg (3.2 × 101 ng/m3).Bacterial counts, with a mean value of 15.9 CFU/m3, showed a seasonal shift, mainly explained by weather (air moisture and temperature) and PM2.5 concentration. The genomic analysis showed Cutibacterium as the dominant genus during the cold months while Bacillus predominated in the warm season.The VOCs with higher average concentrations were acetic acid (130 μg/m3), nonanoic acid (124 μg/m3), benzoic acid (29.7 μg/m3), octanoic acid (19.9 μg/m3) and nonanal (4.70 μg/m3), with the rest of compounds in concentrations below 4 μg/m3. Odorant pollutants with the greatest contribution to olfactory nuisance were aldehydes (from pentanaldehyde to decanaldehyde), acetic acid and phenol.Although the observable effects of the waste treatments were low, several parameters showed an influence on the environment which should be assessed to foresee and prevent long-term consequences.

Physicochemical, sugar, and volatile profile characterization of blong song, bidens, coffee, and mint honeys originating from Vietnam

In this study, the pollen analysis, physicochemical and volatile profiles of blong song, bidens, coffee, and mint honeys from Vietnam were analyzed. The primary pollen content was 87.0%, 37.5%, 5.7%, and 2.7% in the blong song, coffee, bidens, and mint honey, respectively. The average values of the physicochemical properties ranged from 9.4 to 33.5 mS m−1 for electrical conductivity, from 9.5 to 19.7 meq kg−1 for free acidity, from <2 to 10.7 DN for diastase activity, from 0 to 44.7 mm Pfund for color, and from 2.9 to 39.2 mg kg−1 for 5-hydroxymethyl-2-furfural (5-HMF) showed statistically significant differences (p < 0.05) among the four types of honey. Principal component analysis (PCA) of sugars revealed that trehalose was typical for blong song honey; melibiose, sucrose, and maltose for bidens honey; and turanose for mint honey. Using headspace solid phase microextraction coupled with gas chromatography-mass spectrometry (HS-SPME/GC-MS) several specific volatile compounds for each honey type were identified: linalool oxide isomers for blong song honey, acetic acid phenylethyl ester for bidens honey, citral, nonanoic acid, α-terpineol, 1-nonanol, and benzeneacetaldehyde for coffee honey and menthol isomers, and isomethyl acetate for mint honey. The results provide comprehensive data on chemometrics, melissopalynological profiles, and volatile compounds analysis for the classification of honey with different floral origins from Vietnam.

Bioactivity evaluation and active compounds identification of Symphoricarpos orbiculatus as potential botanical herbicide.

Evaluation of herbicidal activity and identification of active compounds are important bases for the development of new botanical herbicides. This study confirmed that Symphoricarpos orbiculatus has high herbicidal activities against mono-dicotyledonous weeds, including Echinochloa crusgalli, Digitaria sanguinalis, Amaranthus retroflexus and Portulaca oleracea. By bioassay-guided isolation, 12 compounds were isolated and identified from S. orbiculatus for the first time, including iridoids: naucledal (K1), loganin (K2), loganigenin (K3), loganin acid (K4), glucologanin (K5) and vogeloside (K6), as well as flavonoids: quercetine (K7), luteolin (K8), nobiletin (K9), astragalin (K10), isorhamnetin 3-d-glucoside (K11) and rutin (K12). Biological assays showed that iridoids are the main active ingredients of S. orbiculatus. The compounds of K5 and K6 could inhibit both the root (IC50 = 37.54 and 38.91 μg mL-1, respectively) and shoot (IC50 = 42.78 and 45.72 μg mL-1, respectively) of Portulaca oleracea, which have a weeding toxicity similar to that of the commercialized plant-based herbicide pelargonic acid. In addition, the results of pot culture assay showed that S. orbiculatus ethanol extracts had high fresh weight control effect against Digitaria sanguinalis and P. oleracea at the concentration of 40 g L-1. After 7 days, both the soil treatment and the stem and leaf spray method resulted in severe leaf necrosis and significant leaf etiolation. Symphoricarpos orbiculatus and its herbicidal active compounds have the potential to develop into botanical herbicides, and are first reported in the present study. © 2024 Society of Chemical Industry.