Achieving patient compliance is a key goal in oral health, necessitating early education on good dental hygiene practices. This study assesses dental hygiene awareness among college students in various disciplines. A questionnaire focusing on knowledge, attitudes, and practices related to dental hygiene was distributed to 400 students from medical, nursing, engineering, and other undergraduate programs, divided into groups of 100 each. The survey also considered economic backgrounds and oral hygiene behaviors. Responses were collected online, with data analyzed using the Chi-square test and Pearson's coefficient to determine statistical significance (P < 0.05). All collected responses were valid, revealing that most students, primarily from middle- or lower-income groups, have a satisfactory level of knowledge regarding oral hygiene. Over 90% recognize its importance for overall health. While practices were generally good, areas for improvement were identified, alongside an overall positive attitude. However, infrequent dental visits were noted as a concern. Focusing on improving oral hygiene attitudes and practices among the younger generation could have long-term benefits, especially in developing countries aiming for better oral health outcomes.