Serous otitis media is also called secretory otitis media or mucoid otitis media. It is characterized by accumulation of nonpurulent effusion in the middle ear cleft and mastoid air cells due to negative pressure produced by dysfunction of the eustachian tube or incomplete resolution of acute otitis media. It is more common occur in children as eustachian tube that connect nasopharynx and anterior wall of middle ear is small and straight. It is characterized by fullness in the ear, mild hearing loss, loss of balance. Symptomatically it can be correlated with Kapha Vataja Badhirya. This case report discusses the Ayurvedic treatment of a case diagnosed as otitis media with effusion, which was posted for myringotomy with grommet insertion. A 42 Year old male patient with complaints of fullness and heaviness of B/L ears along with mild hearing loss since 9 days. The features suggestive of otitis media with effusion were diagnosed by pure tone audiometry and tympanogram. . Management done with OPD based treatment i.e. Vyoshadi Vataka with honey ,Khadridai Vati for chushnarth. Shadabindu Taila for Nasya, Virechana Dhoompaan, gargle with Triphala Yavkut and advised for steam inhalation. Significant result was observed with this treatment protocol in the management of Serous otitis media