Nowadays, Internet of Things (IoT) is invading almost all sectors of life since it is based on connecting living or non-living things together through computer technology. It is responsible for connecting physical objects together through the internet. Healthcare and hospitals are one of the most important sectors that require a lot of attention to transfer their old form of documentation into SMART management systems. It is essential to analyze health data in order to increase the quality of patient’s care. Egypt being a development country is starting to substitute its old governmental systems into electronic SMART technology. IoT devices produce different types of data and transfer them to the cloud computing for storage and analysis. The benefits of using IoT in collecting, transferring, and analyzing patients’ data for the hospitals are attracting a lot of researchers. Therefore, the arrangement of smarter and more money saving healthcare services are becoming highly required. Security and privacy, device communication, and data collection and management are some of the challenges that face the IoT technology especially when used with hospital’s data. Accordingly, a proposed reference model for making SMART hospital management system is under construction in order to achieve the best performance. The model is taking into consideration both the functional and non-functional requirements of the different participants involved in the hospital management system