Abstract Numerous Lie supergroups do not admit superunitary representations (SURs) except the trivial one, for example, Heisenberg and orthosymplectic supergroups in mixed signature. To avoid this situation, we introduce in this paper a broader definition of SUR, relying on a new definition of Hilbert superspace. The latter is inspired by the notion of Krein space and was developed initially for noncommutative supergeometry. For Heisenberg supergroups, this new approach yields a smooth generalization, whatever the signature, of the unitary representation theory of the classical Heisenberg group. First, we obtain Schrödinger-like representations by quantizing generic coadjoint orbits. They satisfy the new definition of irreducible SURs and serve as ground to the main result of this paper: a generalized Stone–von Neumann theorem. Then, we obtain the superunitary dual and build a group Fourier transformation, satisfying Parseval theorem. We eventually show that metaplectic representations, which extend Schrödinger-like representations to metaplectic supergroups, also fit into this definition of SURs.