This paper explores linear waves’ instability in nonuniform complex plasmas with dust size distribution and non-adiabatic dust charge fluctuation. For this purpose, the dispersion relation is obtained with the aid of linearizing the hydrodynamic equations governing the properties of linear waves. The contribution of physical parameters such as inhomogeneity, nonadiabatic dust charge fluctuation, and dust size distribution to the features of dust acoustic waves is examined at great length. The numerical results show that the present research results are very important in the phenomenon of space astrophysical and experimental plasmas.