Most of the published works related to noise generation in high-lift devices only consider clean idealized geometries, whereas real aircraft wings contain important parts called the slat tracks that connect the slat and the main wing. To investigate the effects of slat tracks on the ambient flow and noise, simulations are performed for wings based on the 30P30N airfoil. Two configurations are considered, i.e., the 30P30N wing with and without a slat track. Improved detached-eddy simulation is carried out to compute the unsteady near-field flow. The far-field noise propagation is calculated using the Ffowcs Williams-Hawkings equation. The results show that the installation of the slat track has observable effects on the aerodynamic and aeroacoustic performances of the high-lift devices. The maximum lift coefficient of the high-lift device and the stall angle of attack is reduced. Low-frequency broadband noise radiated from the main wing is significantly increased and the directivity of the overall sound pressure level is changed due to the slat track. The far-field noise from the configuration with the slat track displays noticeable sensitivity to the angle of attack. The slat track has an amplification effect on the high-pressure fluctuation on the main wing, especially at a small angle of attack. This leads to nearly 10 dB in the far-field noise based on the discussed wing section. To reveal the relative noise mechanism, vortical structures near the slat track, large-scale spanwise flows above the main wing, and the vortex dynamics are investigated. A spiral vortex pair is captured as the most important flow structure. It is generated in the spanwise direction by the interaction of slat wakes with the boundary layer on the upper surface of the main wing. The pressure fluctuations on the main wing are highly correlated with this flow structure, which cannot be ignored for the study of noise in a real aircraft.