Nitrogen Co-doped Carbon Nanodots Research Articles

Fluorescent and Biocompatible Nitrogen and Sulfur Co-Doped Carbon Nanodot as an Ocular Fundus Angiography Imaging Agent.

The florescence characteristics and the toxicities of carbon nanodots (CDs) are directly related to their elemental compositions. Fluorescent and non-toxic agent for imaging of biological systems was aimed. Sulfur and nitrogen co-doped CDs (S/N-CDs) was hydrothermally produced in an average size of 8nm. S/N-CDs showed blue fluorescence under UV-light with an excitation wavelength of 365nm. After 24h, S/N-CDs was non-cytotoxic in HUVEC and L929 cells. S/N-CDs have a great potential to act as an alternative material for commercial fluorescent materials with its 85.5% of quantum yield. S/N-CDs was approved in vitro as an imaging agent for an ocular fundus angiography of rats.

Fluorometric and colorimetric determination of hypochlorite using carbon nanodots doped with boron and nitrogen.

Carbon nanodots doped with boron and nitrogen (BN-CDs) with an average diameter of around 11nm were prepared by a hydrothermal approach using adenine and 3-aminobenzene boronic acid as the starting materials. The atomic ratio of boron to nitrogen atomic in the BN-CDs is approximately 1:1. This indicates that a large fraction of N atoms goes lost during preparation because the B/N ratio of the precursors is about 1:6. The BN-CDs display blue fluorescence (best measured at excitation/emission wavelengths of 305/380nm) which is independent of the excitation wavelength. On exposure to hypochlorite anion, fluorescence is quenched and the color of the solutions changes from yellow to brown. Fluorescence drops linearly in the 0.1-1000μM hypochlorite concentration range. The colorimetric response, best measured as the absorbance ratioat 236/260nm, ranges from 0.3 to 4.0mM. The color changes can be readily detected visually. The probe was applied to the determination of hypochlorite in living cells and in (spiked) tap water. Graphical abstract Excitationwavelength-independent fluorescent boron and nitrogen codoped carbon nanodots (BN-CDs) were obtainedbya hydrothermal approach. The BN-CDs were usedto detect hypochlorite in wastewaterby afluorometric and colorimetric dual-readout assay.