As a promising anode with non-obvious volume change during the intercalation/extraction of Li+ for advanced lithium-ion batteries (LIBs), the application of TiO2 is hindered by the poor electronic/ionic conductivity. Herein, a coherent strategy is carried out to obtain anatase-rutile TiO2 dual-phase composited with NiS2 nanoparticles confined in carbon nanotubes (A/R-TiO2/NiS2/CNTs) derived from Ti-MOF. The inclusion of NiS2 can significantly enhance the capacity of the composite. Simultaneously, the biphasic anatase-rutile TiO2 can induce plenty of oxygen vacancies to expedite the diffusion of lithium ions. The transfer of electrons can be accelerated by the surrounding carbon nanotubes with outstanding conductivity, which also enhance the structural stability of the whole composite. Thanks to the above appealing properties, the A/R-TiO2/NiS2/CNTs electrode delivers excellent rate capacity of 707.4 mA h g−1 at 0.1 A g−1 and 131.9 mA h g−1 at 5 A g−1 and displays 401.5 mA h g−1 at 0.5 A g−1 after 600 cycles.