Nickel Chloride Solution Research Articles

Solution-processed NiS thin films: structural, morphological, compositional and optical analysis

Abstract The present work elucidates a study on the synthesis and characterization of nanostructured NiS thin films, an optical absorber material. NiS films have been deposited on glass substrates using a simple and cost-effective chemical solution route. The deposition process has been accomplished using an aqueous solution of nickel chloride, thiourea, ammonia and Triton. As-deposited and thermally annealed films have been characterized using X-ray diffractometry, Fourier transform infrared spectrometry, scanning electron microscopy, atomic force microscopy, energy dispersive X-ray spectroscopy, and UV–visible spectrometry. It has been observed that the deposited films are nanocrystalline in nature and belong to the rhombohedral structure of the millerite phase. The diffraction peaks become more sharp, discrete and intense whereas the crystallite size increases from 9.89 to 11.78 nm with annealing treatment. Some variations in the infrared peaks have been observed with annealing. The characteristic peak for Ni–S vibration has been observed at ∼604 cm−1. The surface of the films is smooth, uniform, and free from cracks and pinholes. The optical absorbance analysis has confirmed that NiS films possess a direct optical band gap whose values vary from 1.50 to 1.45 eV with annealing.

Low-cost visible spectrophotometer for detecting absorption and emission in metallic blends of colorful samples solution

The innovative, affordable assembled visible spectrophotometer employed in this study aims to analyze the absorption and emission of colorful metallic blends of colorful samples solution. It features a tungsten white light bulb source, an ammeter as a detection element, a digital voltmeter, a diffraction grating for light dispersion, a converging lens for light collimation, and filters of various wavelengths (blue, red, yellow, and yellow-green). The light bulb source was powered by a standard supply set at 6 V. Using metallic solutions of chromium chloride (CrCl3) and copper sulphate (CuSO4) with different filter wavelengths, the performance was assessed. The transmittance and absorbance of these metallic solution samples exhibit a linear relationship with approximately 3 % deviation compared to results from a commercial UV–VIS spectrophotometer (DR-6000). Similar investigations were conducted with equivalent quantities of CuSO4, CrCl3, and nickel chloride (NiCl2) solutions, showing a discrepancy ranging from 2 % to 8 % when compared with the commercial UV–VIS spectrophotometer. Therefore, in low-income countries like Ethiopia, colorful metallic solution samples can be effectively analyzed using the newly designed low-cost spectrophotometer.

Elastoplastic properties of ion exchangers based on cross-linked polyelectrolytes

In this paper, we dilatometrically studied the elastoplastic properties of spherical grains of industrial weakly acidic and strongly acidic ion-exchanger in experiments with constant uniaxial compression and a subsequent unload at room temperature, depending on the ionic form and concentration of the electrolyte solution. It was found that the ionic form of polyacrylate and polymethacrylate cross-linked with triethylene glycol dimethacrylate and divinylbenzene, respectively, and the concentration of the external solution affects their elastoplastic properties. In dilute solutions of sodium chloride and calcium chloride, the gels exhibited elastic properties with close relative amplitudes of deformation. The amplitude of deformation of the grain of polymethacrylate crosslinked with divinylbenzene, in the Ni form, in a dilute nickel chloride solution was significantly lower than that of the Ca form, with significant plastic deformation. With an increasing concentration of the external solution of calcium and nickel chlorides under mechanical load on the grain of polymethacrylate cross-linked with divinylbenzene, the total deformation of the granule and the magnitude of elastic deformation decreased, while the residual (plastic) deformations increased. In concentrated solutions of CaCl2 and NiCl2, such an ion-exchanger became an inelastic rigid material. Even under increased mechanical load, the magnitude of its elastic compressive deformation was very small. The K-form of a swollen in water strongly acidic polystyrene cation-exchanger with grafted sulpho groups cross-linked with divinylbenzene is also characterized by elastic deformations, i.e. the polymer is in a highly elastic state. However, the polystyrene matrix is more rigid compared to polyacrylic and polymethacrylic cation-exchangers in the alkali metal ion form, so the amplitude of deformation is significantly smaller. For such a cation-exchanger in Ca- and Ni- forms, elastic deformations prevail even in concentrated solutions.

Carbon nanotubes with CoNi alloy nanoparticles growing on porous carbon substrate as cathode for Li-CO2 batteries

The over-exploitation of fossil fuels and rapid industrialization has released a large number of carbon dioxide. As a major greenhouse gas, it can induce the increasing global temperature and result in environmental issues. It is an urgent necessity to reduce carbon dioxide emission and increase carbon capture, utilization and storage. Li-CO2 battery can be used for the fixation and conversion of carbon dioxide to electrochemical energy. However, it is necessary to explore and design efficient catalysts, due to the low electronic conductivity and sluggish decomposition kinetics for lithium carbonate as the discharge product. Herein, carbon nanotubes with CoNi alloy nanoparticles growing on porous carbon substrate (PC/CoNi-CNTs) is designed by immersing porous melamine formaldehyde sponge into cobalt nitrate and nickel chloride solution with the subsequent carbonization. The porous structure of carbon substrate facilitates the electrolyte infiltration and carbon dioxide diffusion. The carbon nanotubes and CoNi alloy catalysts can efficiently enhance the reversible deposition and decomposition of lithium carbonate and carbon, taking advantage of their synergistic effect. At a current density of 0.05 mA cm−2, the terminal discharge and charge voltages are 2.76 and 4.23 V with a limited specific capacity of 0.2 mA h cm−2, respectively. These results demonstrat that the design of carbon nanotubes with alloy nanoparticles on porous carbon substrate as cathode can enhance the electrochemical performances of Li-CO2 battery.

Potentiodynamic Study of The Effects of Nickel on The Electrodeposition of Zinc from Chloride Media

Abstract. The potentiodynamic experiments of the nickel effects on the zinc electrodeposition have been done to understand the impact of Ni impurities on the electrowinning of Zn from spent pickling liquor. The nickel chloride solutions of Ni concentrations 90 and 1 g/dm3 were used as the electrolytes. The latter was also mixed with 90 g/dm3 Zn in the experiments. All the runs were carried out at room temperature with 40 mV/s continuous polarization speed and with 1/s sampling rate. It was observed that nickel electrodeposition from chloride media containing 90 g/dm3 Ni started with the generation of hydrogen bubbles, entirely blocking the cathode surface. Only a slight current development was observed until the polarization potential ~ -0,8 V. The visual observation showed bubbles also formed at the anode, which may represent chlorine and/or oxygen evolution. While, in the electrodeposition of nickel with only 1 g/dm3 Ni concentration in the electrolyte, metal deposition was hardly observed, but visible hydrogen bubbles constantly blocked the cathode surface. A similar tendency was observed in the mixed-solution electrolysis cell; the initial tiny bubbles accumulated at the cathode surface more than in the pure Zn solution. The enhancement of H2 evolution indicates how nickel deposition may contribute to the loss of useful current in the process of Zn electrodeposition. The mass of nickel deposited from the mixed solutions significantly decreases as the Ni concentration decreases in the electrolyte, while the mass of deposited zinc is relatively constant. It means that the purity of the produced Zn is appreciably higher – with respect to Ni – if nickel is efficiently eliminated from the solution before electrowinning.

THE INFLUENCE OF SODIUM CARBOXYMETHYL CELLULOSE ON THE SEDIMENTATION BEHAVIOUR OF NICKEL PHOSPHATE PRECIPITATE AT VARYING TEMPERATURES

The sedimentation data of nickel phosphate precipitate formed with or without a modifier - sodium carboxymethyl cellulose (Na-CMC) biopolymer were studied under controlled conditions of temperature. The main objective was to access the influence of Na-CMC and temperature on On-set Sedimentation Rate (OSR) and Sedimentation Volume Ratio (SVR) of nickel phosphate. Na-CMC at different concentrations (200ppm - 2000ppm) was mixed with constant volume of disodium hydrogen phosphate solution in a graduating measuring cylinder. On mixing the resulting solution with constant volume of nickel chloride solution, a precipitate was formed, stirred for 1 min and placed in the sedimentation measurement device - PreSed Meter. The settling of the precipitate was monitored and recorded at different temperatures (30oC, 40oC and 50oC). Blank sedimentation (0ppm Na-CMC) was also run at various temperatures by adding 10ml of deionized water (instead of 10ml of Na-CMC solution). A plot of precipitate displacement per settling time established a logarithmic curve which flattened with time. Regression analyses of OSR (0.71 ≤ R2 ≥ 0.94) and SVR (0.51 ≤ R2 ≥ 0.93) indicated the dependence of sedimentation on concentration of Na-CMC thus implying chemical interaction between the chemical species.

Allergenicity and Bioavailability of Nickel Nanoparticles Compared to Nickel Microparticles in Mice

Metal allergy is a common disease that afflicts many people. Nevertheless, the mechanism underlying metal allergy development has not been completely elucidated. Metal nanoparticles might be involved in the development of a metal allergy, but the associated details are unknown. In this study, we evaluated the pharmacokinetics and allergenicity of nickel nanoparticles (Ni-NPs) compared with those of nickel microparticles (Ni-MPs) and nickel ions. After characterizing each particle, the particles were suspended in phosphate-buffered saline and sonicated to prepare a dispersion. We assumed the presence of nickel ions for each particle dispersion and positive control and orally administered nickel chloride to BALB/c mice repeatedly for 28 days. Results showed that compared with those in the Ni-MP administration group (MP group), the Ni-NP administration group (NP group) showed intestinal epithelial tissue damage, elevated serum interleukin (IL)-17 and IL-1β levels, and higher nickel accumulation in the liver and kidney. Additionally, transmission electron microscopy confirmed the accumulation of Ni-NPs in the livers of both the NP and nickel ion administration groups. Furthermore, we intraperitoneally administered a mixed solution of each particle dispersion and lipopolysaccharide to mice and then intradermally administered nickel chloride solution to the auricle after 7 days. Swelling of the auricle was observed in both the NP and MP groups, and an allergic reaction to nickel was induced. Particularly in the NP group, significant lymphocytic infiltration into the auricular tissue was observed, and serum IL-6 and IL-17 levels were increased. The results of this study showed that in mice, Ni-NP accumulation in each tissue was increased after oral administration and toxicity was enhanced, as compared to those with Ni-MPs. Orally administered nickel ions transformed into nanoparticles with a crystalline structure and accumulated in tissues. Furthermore, Ni-NPs and Ni-MPs induced sensitization and nickel allergy reactions in the same manner as that with nickel ions, but Ni-NPs induced stronger sensitization. Additionally, the involvement of Th17 cells was suspected in Ni-NP-induced toxicity and allergic reactions. In conclusion, oral exposure to Ni-NPs results in more serious biotoxicity and accumulation in tissues than Ni-MPs, suggesting that the probability of developing an allergy might increase.

A simulation of methane hydrate formation in nickel chloride solution

Heavy metal is a potential threat to human, and hydrate-based method was one potential method proposed for heavy metal removal. In order to get a better understanding of the mechanism for heavy metal removal by hydrate-based method, simulation of methane (CH4) hydrate formation in nickel chloride (NiCl2) solution was conducted from molecular level by using Gromacs-2020.3 software. From the simulation results, CH4 hydrate formed in NiCl2 solution can be judged from the increasing of four-body structural order parameters (F4) and the decreasing of total energy. Hydrate or interfacial hydrate rather than ice was the main solid structure via CHILL + Algorithm analysis. All nickel chloride was repelled out of CH4 hydrate during 2000 ns of simulation, which corresponded with the salt-removing effect. The simulation results also indicated that chloride ion accelerated the nucleation of CH4 hydrate no matter the cation was Na+ or Ni2+. Finally, CH4 hydrate with both Structure I (sI) and Structure II (sII) were formed in NiCl2 solution in 2000 ns of simulation, and sI type hydrate was the main CH4 hydrate structure in NiCl2 solution.

Synthesis and characterization of nickel nanoparticles formed by solution cold plasma jet

In this work, nickel nanoparticles were prepared from nickel chloride solution using the liquid phase plasma reduction technique. A cold plasma jet was used for this purpose. The variation of the concentrations 0.5mM, 1mM and 2 mM and was used to study optimal condition of nickel nanoparticles formation. A concentration of 1 ml was observed to be the best, by using UV-Vis spectroscopy and Field emission scanning electron microscopy (FESEM). The optimum concentration was used to formation nanoparticles solution with variation the exposure time of cold plasma jet at (5 min, 10 min, 15 min ) respectively. The results shown by UV-Vis spectroscopy the nanoparticle peaks produced by surface plasmon absorption were observed around 365-375 nm according the discharge time of cold plasma. The nanoparticles were spherical homogenous as observed by Field emission scanning electron microscopy (FESEM) which also shown the average particle size about 25nm, and by dynamic light scattering (DLS) and also zeta potential (ZP) measurements were observed non-aggregated in the long term, the particles are very stable colloid, also no visible aggregation have been seen on the prepared samples in this concentration (1mM). In contrast to other concentrations which showed a nonhomogeneous morphology and aggregated. X-ray Diffraction (XRD) showed that NiNPs have a face-centered cubic (FCC) structure with a crystalline size of around 12.5 nm, and also Inductively Coupled Plasma mass Spectrometry (ICP-mass) were used to characterize the prepared samples.

Preparation and Characterizations of NiS/ZnS Bilayer Thinfilm by Chemical Bath Deposition Method

NiS/ZnS thin films were grown by Chemical Bath Deposition (CBD) technique using eqimolar aqueous solutions of zinc chloride, nickel chloride and thiourea as precursor. Silicon glass substrates were placed in glass bottles with polypropylene autoclave screw caps containing the precursors described above, and the bath temperature is maintained at 95°C. X-ray diffraction 28/8 scans showed that the only crystallographic phase present was the hexagonal wurtzite structure. Scanning electron microscopy showed the formation of nanostructures, consisting of hexagonal structures of a few hundred nanometers. The photoluminescence spectra of NiS/ZnS bilayer were recorded at 18-295 K using a cw He-Cd laser (325 nm) and pulsed laser (266 nm). The NiS/ZnS nanostructure exhibit an ultraviolet emission band centered at ;:::; 3.87eV in the vicinity of the band edge, which is attributed to the well-known excitonic transition in ZnS. The optical properties such as refractive index, electrical and optical conductivities were determined by using UV- VIS absorption spectrometry. The band gap energy was determined as 1.45 eV.

Structural, morphological and magnetic properties of Ni/NiO systems produced by a sorbitol-assisted wet chemical method

In this work, we show the sorbitol-assisted synthesis method to produce polycrystalline Ni/NiO systems with different phase proportions. The samples were prepared from heat treatment of an aqueous solution of nickel chloride and sorbitol by using a simple wet chemical approach. The produced samples were calcined at 500 °C and the characterization of the as-produced samples was performed by X-ray diffraction (XRD), Rietveld analysis and scanning electron microscopy (SEM). Magnetic properties of Ni/NiO samples were investigated by DC magnetometry technique. XRD data reveal an increase in the proportion of metallic Ni phase in the synthesis products as the quantity of sorbitol in the starting solution is increased. Multi-phase Rietveld analysis showed that the phase fractions in the samples varied from 5.9 wt% (94.1 wt%) to 22.5 wt% (77.5 wt%) for Ni (NiO) phase. SEM analyses show changes in particle shape and size when sorbitol increases. The increase in the magnetization with increasing of Ni phase content up to at 65 kOe is assigned to the increase of the ferromagnetic (FM) phase.

Structural and Electrokinetic Characteristics of High-Silica Porous Glasses in Nickel Chloride Solutions

Structural and Electrokinetic Characteristics of High-Silica Porous Glasses in Nickel Chloride Solutions

Extraction of Iron(III) from Nickel Chloride Solutions by Mixtures of Aliphatic Alcohols and Ketones

ABSTRACT The article presents studies on the extraction of iron from chloride solutions with aliphatic alcohols, ketones, and their mixtures. Dilution of 1-octanol with an inert aromatic diluent to a concentration of 80 vol.% led to an increase in its extraction capacity, while the extraction capacity of 2-octanone has decreased with dilution. A synergistic effect was found for a 1-octanol/2-octanone mixture, the maximum of extraction was observed at a ketone concentration of 80 vol.%. The effect of a mixture composition and chloride ion concentration on the iron extraction degree was studied. McCabe-Thiele results indicated that at Fe(III) concentration in the aqueous phase 9.32 g∙dm−3, it is possible to extract iron(III) quantitatively using a mixture of alcohols C8+C10 (70 vol.%) and 2-undecanone (30 vol.%) after three extraction stages. Stripping of Fe(III) from the mixture was done with distilled water. After the stripping, the loaded Fe(III) concentration in the organic phase was reduced from 27 g∙dm−3 to <0.001 g∙dm−3 for 3 stages. The conditions were tested in continuous mode at a cascade of laboratory extractors. During the tests on the cascade, the low solubility of the mixture of ketone with alcohol was established, and the concentrated solution of ferric chloride was obtained.

Extraction of Chloro Complexes of Copper and Silver from Nickel Chloride Solutions

Investigations into the recovery of copper(II) and silver(I) by liquid extraction with individual extractants and mixtures based on tertiary amine from nickel chloride solutions have been carried out. The influence of the modifier type, chloride background, extractant concentration, and the ratio of aqueous and organic phases on the extraction process is found.

Remarkably Enhanced Hydrogen Oxidation Reaction Activity of Carbon-supported Pt by Facile Nickel Modification

Developing high activity catalysts for hydrogen oxidation reaction(HOR) under alkaline condition remains a challenge in the exchange membrane fuel cell(AEMFC). Herein, we report that the activity of carbon-supported platinum(Pt/C) towards the hydrogen oxidation reaction(HOR) in alkaline media can be remarkably enhanced by simple immersion of Pt/C in nickel chloride solution. The adsorption of hydrogen on the catalyst surface is weakened by modification of nickel. The HOR activity on the Pt/C after immersion possesses an excellent mass current density of 33.4 A/gmetal, which is 18% higher than that(28.3 A/gmetal) on Pt/C.

Mathematical modelling of mass transfer of paramagnetic ions through an inert membrane by the transient magnetic concentration gradient force

The objective of this work is to suggest a mathematical model for mass-transfer of a paramagnetic electrolyte, nickel(ii)chloride solution, through an inert, thin membrane from one chamber to another under the influence of magnetic fields which are applied perpendicular to the membrane. The model is based on the magnetic concentration gradient force, the Fick’s law of diffusion, and the Hagen-Poiseuille law for paramagnetic ion transport in the membrane. The magnetic concentration gradient force is found to be elusive and points in the direction of the magnetic field, in our case, the direction of the Fick diffusion flux. The reason is the gradient of the magnetic volume susceptibility for the electrolyte in the membrane, which decreases in the direction of the magnetic field. This is in accordance with the variable-reluctance principle. Mass balances for transport of Ni ions in distilled water through the membrane are derived and governed by a partial differential equation in one-dimensional space and time with specified initial and boundary conditions. The associated flux is superimposed on the pure Fick diffusion flux. The total flux is described by a nonlinear partial differential equation, which has not previously been used to describe transfer phenomena in paramagnetic solutions in magnetic fields. The simulated results were compared with experimental results and coincide approximately in all points for unstirred solutions. In stirred solutions, where the mass transfer coefficient at the membrane inlet approaches infinity if the mixing is ideal, no experimental or simulated effect was observed of the magnetic field.

Anionic polysaccharide stabilized nickel nanoparticles-coated bacterial cellulose as a highly efficient dip-catalyst for pollutants reduction

This article presents the preparation and catalytic performance of carboxymethyl cellulose stabilized nickel nanoparticles (CMC-Ni) and bacterial cellulose coated with it (CMC-Ni-BC) in the colloidal form and dip-catalyst, respectively. Ni nanoparticles were prepared by mixing nickel chloride and CMC aqueous solutions with reductant followed by quick microwave heating treatment. In a separate experiment, BC was synthesized by Gluconacetobacter xylinum. After purification, the synthesized BC was coated with the prepared CMC-Ni. The CMC-Ni-BC catalytic efficiency was evaluated in anionic 2-nitrophenol (2-NP) and cationic methylene blue (MB) dye reduction reactions by sodium borohydride. While using the similar reaction conditions for the 2-NP reduction, the suspension form of CMC-Ni catalyst showed higher reduction reaction rate constant as compared to the dip-catalyst of CMC-Ni-BC. Similarly, high reaction rate constant was observed for the CMC-Ni in comparison with the CMC-Ni-BC while performing the MB reduction reaction. However, supported type Ni catalyst was easily applied in further reactions without the need of further processing which is needed in the case of colloidal form of the catalyst. Moreover, the CMC-Ni-BC catalyst was also tested in the complex situation using the binary solution of 2-NP and MB for their simultaneous reductions. As high as 7.89 min−1 of reaction rate constant was calculated for the reduction of cationic MB by anionic polysaccharide stabilized Ni nanoparticles-coated BC.

Electrocatalytic properties of a cerium/nickel coating deposited using a deep eutectic solvent

A cerium/nickel coating was deposited using the chronopotentiometry method from a solution of nickel chloride, cerium chloride, ammonium chloride and boric acid dissolved in a deep eutectic solvent – choline chloride:ethylene glycol mixture in the ratio 1:2. The obtained layer included approximately 85% of Ce and 15% of Ni. The kinetics of the hydrogen evolution reaction (HER) were studied in 1 M KOH. The synthesized coating exhibited enhanced electrochemical performance towards the hydrogen evolution reaction in water electrolysis. The overpotential of this reaction was reduced in comparison to the reference nickel layer and the exchange current density was higher than that reported for the Ni layer.

Extraction of Iron(III) from Chloride Nickel Solutions with Aliphatic Ketones

Extractive recovery of iron(III) from chloride nickel solutions with macromolecular aliphatic ketones was studied. It was found that the extraction of Fe(III) grows with increasing concentration of chloride ions in solution. For the hydrochloric acid solution, the maximum degree of extraction (99%) is observed at an HCl concentration < 6 mol dm−3. For the nickel chloride solution the highest extraction (95%) is reached at a Cl− concentration ≥ 8 mol dm−3. A high selectivity of ketones with respect to iron(III) was demonstrated, they hardly extract such microscopic impurities as Cu2+ and Co2+, as well as the macroscopic component Ni2+. The optimal ratio between the organic and aqueous phases for washing the extract to remove the carried-away nickel was determined. Enlarged laboratory tests on deep separation of iron and nickel were performed. As a result, a solution of ferric chloride with Fe(III) concentration of 76.8 g dm−3 with total content of nickel(II), cobalt(II), and copper(II) impurities less than 0.022 g dm−3.

Влияние хлорида никеля на показатели гемокоагуляции и липопероксидации у крыс в эксперименте

Цель исследования - изучить состояние системы гемостаза при хронической интоксикации хлоридом никеля, исследовать взаимосвязь показателей гемокоагуляции с процессами липопероксидации у крыс в эксперименте. Методика. Опыты проводили на крысах-самцах Вистар (n=50, 230-250 г). Раствор NiCl2 (5 мг/кг) вводили внутрижелудочно ежедневно в течение 2 нед, 1 и 2 мес. По завершении эксперимента исследовали состояние тромбоцитарного и коагуляционного звеньев гемостаза, антикоагулянтную и фибринолитическую активность крови, а также определяли активность процессов перекисного окисления липидов и антиоксидантных ферментов. Результаты. Установлено, что через 2 нед и 1 мес интоксикации у крыс отмечались гиперкоагуляционные изменения показателей свертывающей системы крови: повышение агрегационной активности тромбоцитов, увеличение концентрации фибриногена, снижение активированного частичного тромбопластинового времени (АЧТВ) и протромбинового времени. В этот период регистрировалось увеличение антитромбиновой и фибринолитической активности крови. Через 2 мес наблюдалось подавление активности клеточного звена гемостаза - тромбоцитопения, ослабление степени АДФ-индуцируемой агрегации тромбоцитов. Выявлялась тенденция к уменьшению концентрации фибриногена. На фоне снижения АЧТВ и тромбинового времени отмечалось увеличение протромбинового времени. В то же время регистрировалось угнетение противосвертывающего звена системы гемостаза (снижалась активность антитромбина III), наблюдалось истощение резервных возможностей фибринолитического звена (замедление фXIIа-зависимого эуглобулинового лизиса) и увеличение содержания растворимых фибрин мономерных комплексов, что свидетельствует о наличии тромбинемии. Через 2 нед, один и два месяца интоксикации у животных выявлялись корреляционные связи между основными показателями системы гемостаза и активностью процессов перекисного окисления липидов и антиоксидантных ферментов. Заключение. Полученные данные подтверждают наличие взаимосвязи активности процессов липопероксидации и системы гемостаза, в том числе при хронической никелевой интоксикации. Результаты исследования позволяют рекомендовать применение антиоксидантов для разработки способов коррекции гемостатических сдвигов при воздействии на организм тяжелых металлов. The aim. To study the state of the hemostasis system in chronic nickel intoxication and to investigate the relationship between hemocoagulation indices and lipoperoxidation processes in rats. Methods. Experiments were carried out on male Wistar rats (n=50, 230-250 g). A solution of nickel chloride (5 mg/kg) was administered daily intragastrically for two weeks, one and two months. At the end of the experiments, indices of platelet and coagulation hemostasis systems, anticoagulant and fibrinolytic activity of blood plasma, and activities of lipid peroxidation and antioxidant enzymes were studied. Results. Hypercoagulative changes in indices of the coagulation system were observed in rats after two weeks and one month of intoxication, including increased platelet aggregation and fibrinogen concentration and shortened activated partial thromboplastin time and prothrombin time. During the same period, increased antithrombin and fibrinolytic activities were observed. The depressed activity of the cellular component of hemostasis evident as thrombocytopenia and impaired ADP-induced platelet aggregation was detected after two months of intoxication. A tendency to decrease in fibrinogen concentration was observed. The shortened activated partial thromboplastin time and thrombin time were associated with prolonged prothrombin time. At the same time, inhibition of the anticoagulant component of hemostasis (decreased antithrombin III activity), exhaustion of the fibrinolysis system reserve (delayed fXIIa-dependent euglobulin lysis), and a significant increase in soluble fibrin monomeric complexes indicative of thrombinemia were observed. After two weeks, one and two months of nickel intoxication, a correlation was found between the major indices of the hemostasis system and the activities of lipid peroxidation and antioxidant enzymes. Conclusion. The study confirmed a relationship between the lipid peroxidation activity and the hemostasis system, specifically in chronic nickel intoxication. This result allows to recommend the use of antioxidants in developing methods for correction of hemostatic induced affected by heavy metals.