New Class Of Technologies Research Articles

Carbon carrier-based rapid Joule heating technology: a review on the preparation and applications of functional nanomaterials.

Compared to conventional heating techniques, the carbon carrier-based rapid Joule heating (CJH) method is a new class of technologies that offer significantly higher heating rates and ultra-high temperatures. Over the past few decades, CJH technology has spawned several techniques with similar principles for different application scenarios, including ultra-fast high temperature sintering (UHS), carbon thermal shock (CTS), and flash Joule heating (FJH), which have been widely used in material preparation research studies. Functional nanomaterials are a popular direction of research today, mainly including nanometallic materials, nanosilica materials, nanoceramic materials and nanocarbon materials. These materials exhibit unique physical, chemical, and biological properties, including a high specific surface area, strength, thermal stability, and biocompatibility, making them ideal for diverse applications across various fields. The CJH method is a remarkable approach to producing functional nanomaterials that has attracted attention for its significant advantages. This paper aims to delve into the fundamental principles of CJH and elucidate the efficient preparation of functional nanomaterials with superior properties using this technique. The paper is organized into three sections, each dedicated to introducing the process and characteristics of CJH technology for the preparation of three distinct material types: carbon-based nanomaterials, inorganic non-metallic materials, and metallic materials. We discuss the distinctions and merits of the CJH method compared to alternative techniques in the preparation of these materials, along with a thorough examination of their properties. Furthermore, the potential applications of these materials are highlighted. In conclusion, this paper concludes with a discussion on the future research trends and development prospects of CJH technology.

A Biodegradable Hybrid Micro/Nano Conductive Zinc Paste for Paper‐Based Flexible Bioelectronics

AbstractPaper‐based electronics are emerging as a new class of technology with broad areas of application. Despite several efforts to fabricate new types of flexible electronic devices by screen printing of conductive paste, many of them are often nonbiodegradable, toxic, and expensive, limiting their practical use in bioresorbable paper‐based electronics. To address this need, a highly conductive and biodegradable bimodal conductive paste is developed using cost‐effective zinc‐based micro and nanoparticles with a facile low‐temperature sintering process compatible with paper substrates. The two‐step sintering process involves the removal of the insulating zinc oxide layer by spray coating acetic acid followed by a heat press sintering process to ensure the formation of highly packed and continuous metallic traces. The required conditions for the heat press sintering process are systematically studied using electrical, optical, and mechanical characterization techniques. The results of these investigations revealed an ultra‐packed microstructure with high electrical conductivity (0.5 × 105 S m−1) and low oxide content that is obtained with a heat press sintering setting of 220 °C for 60 s. Finally, as a proof of concept, the conductive paste with an optimized sintering process is used to fabricate a wearable wireless heater for remote‐controlled release of therapeutics. The controlled delivery of the system is validated in the practical and on‐demand delivery of antibiotics for eradicating commonly found bacteria such as Staphylococcus aureus in dermal wound infections. The biocompatibility of all the materials and manufacturing process is validated by NIH/3T3 fibroblast cells via MTT assay and live/dead staining.

Efficiency improvement in non-enzymatic H2O2 detection induced by the simultaneous synthesis of Au and Ag nanoparticles in an RGO/Au/Fe3O4/Ag nanocomposite

Developing a quick and precise technique for hydrogen peroxide (H2O2) detection would open up a new class of technologies for biological, medical and chemical applications.

High-Parameter Single-Cell Analysis.

Thousands of transcripts and proteins confer function and discriminate cell types in the body. Using high-parameter technologies, we can now measure many of these markers at once, and multiple platforms are now capable of analysis on a cell-by-cell basis. Three high-parameter single-cell technologies have particular potential for discovering new biomarkers, revealing disease mechanisms, and increasing our fundamental understanding of cell biology. We review these three platforms (high-parameter flow cytometry, mass cytometry, and a new class of technologies called integrated molecular cytometry platforms) in this article. We describe the underlying hardware and instrumentation, the reagents involved, and the limitations and advantages of each platform. We also highlight the emerging field of high-parameter single-cell data analysis, providing an accessible overview of the data analysis process and choice of tools.

Out of Site

GrabYourWallet, #boycottNRA and other online boycott campaigns have attracted substantial public interest in recent months. However, a number of significant challenges are preventing online boycotts from reaching their potential. In particular, complex webs of brands and subsidiaries can make it difficult for participants to conform to the goals of a boycott. Similarly, participants and organizers have limited visibility into a boycott's progress. This affects their ability to use sociotechnical innovations from social computing to incentivize participation. To address these challenges, this paper makes a system contribution: a new boycott tool called Out of Site . Out of Site uses lightweight automation to remove obstacles to successful online boycotts. We describe the design challenges associated with Out of Site and report results from two phases of deployment with the GrabYourWallet and Stop Animal Testing boycott communities. Our findings highlight the potential of boycott-assisting technologies and inform the design of this new class of technologies. Finally, like is the case for many systems in social computing, while we designed Out of Site for pro-social uses, there are a number of easily predictable ways in which the system can be leveraged for anti-social purposes (e.g. exacerbating filter bubble issues, empowering boycotts of businesses owned by racial, ethnic, and religious minorities). As such, we developed for this project a new, very straightforward design approach that treats preventing these anti-social uses as a top-tier design concern. This approach stands in contrast to the status quo of ignoring potential anti-social uses and/or considering them to be a secondary design priority. We discuss how our simple approach may help other research projects reduce their potential negative impacts with minimal burden.

On the security of consumer wearable devices in the Internet of Things.

Miniaturization of computer hardware and the demand for network capable devices has resulted in the emergence of a new class of technology called wearable computing. Wearable devices have many purposes like lifestyle support, health monitoring, fitness monitoring, entertainment, industrial uses, and gaming. Wearable devices are hurriedly being marketed in an attempt to capture an emerging market. Owing to this, some devices do not adequately address the need for security. To enable virtualization and connectivity wearable devices sense and transmit data, therefore it is essential that the device, its data and the user are protected. In this paper the use of novel Integrated Circuit Metric (ICMetric) technology for the provision of security in wearable devices has been suggested. ICMetric technology uses the features of a device to generate an identification which is then used for the provision of cryptographic services. This paper explores how a device ICMetric can be generated by using the accelerometer and gyroscope sensor. Since wearable devices often operate in a group setting the work also focuses on generating a group identification which is then used to deliver services like authentication, confidentiality, secure admission and symmetric key generation. Experiment and simulation results prove that the scheme offers high levels of security without compromising on resource demands.

From ‘automation’ to ‘autonomy’: the importance of trust repair in human–machine interaction

Modern interactions with technology are increasingly moving away from simple human use of computers as tools to the establishment of human relationships with autonomous entities that carry out actions on our behalf. In a recent commentary, Peter Hancock issued a stark warning to the field of human factors that attention must be focused on the appropriate design of a new class of technology: highly autonomous systems. In this article, we heed the warning and propose a human-centred approach directly aimed at ensuring that future human–autonomy interactions remain focused on the user’s needs and preferences. By adapting literature from industrial psychology, we propose a framework to infuse a unique human-like ability, building and actively repairing trust, into autonomous systems. We conclude by proposing a model to guide the design of future autonomy and a research agenda to explore current challenges in repairing trust between humans and autonomous systems.Practitioner Summary: This paper is a call to practitioners to re-cast our connection to technology as akin to a relationship between two humans rather than between a human and their tools. To that end, designing autonomy with trust repair abilities will ensure future technology maintains and repairs relationships with their human partners.

In-Plane Shape-Deviation Modeling and Compensation for Fused Deposition Modeling Processes

Additive manufacturing (AM) or 3-D printing refers to a new class of technologies that actively construct products directly from any 3-D digital model. In the future, the broader applications of AM will require a cost reduction of AM machines. Currently, the products fabricated by low-end machines, such as those fabricated using fused deposition modeling (FDM) processes, suffer from the issue of low dimensional accuracy due to multiple error sources. To properly manage error sources for improved prevision, this paper proposes a novel strategy for error compensation in the FDM processes. First, we consecutively attribute the dimensional inaccuracy to two major error sources that affect the geometric shape of the product: 1) positioning error of the extruder and 2) shape deformation induced by processing error, including material phase change and other variations that occur. The extruder positioning error is characterized by a Kriging model, while the modeling of shape deformation due to processing error follows the method developed by Huang et al. Second, using error equivalence concept, we transform the positioning error into the equivalent amount of design input error. Finally, we adjust the design to compensate for the overall shape deviation. To validate this strategy, we conduct a designed experiment for the shape deviation prediction and the compensation. The experimental results successfully demonstrate the effectiveness of the proposed three-step strategy to manage multiple error sources in the FDM processes.

Energy band engineering of flexible gallium arsenide through substrate cracking with pre‐tensioned films

Flexible electronics based on the otherwise rigid conventional crystalline semiconductors is emerging as a new class of technology. However, the existing layer‐transfer approaches for implementing such technologies is mostly focused on maintaining the performance of the original device. Here we show that layer transfer through substrate cracking with a pre‐tensioned nickel film readily enables the manipulation of the electronic band structure in flexible gallium arsenide (GaAs) devices. We empirically and theoretically quantify the effect of ‘engineered' residual strain on the electronic band structure in these flexible GaAs devices. Photoluminescence and quantum efficiency measurements indicate the widening of the GaAs energy bandgap due to the residual compressive strain. The experimental results are in good agreement with our theoretical calculations. This study introduces a new way for strain engineering in flexible compound semiconductors with important implications for electronic and optoelectronic applications. (© 2016 WILEY‐VCH Verlag GmbH &Co. KGaA, Weinheim)

AirJump: Using Interfaces to Instantly Perform Simultaneous Extractions.

Analyte isolation is an important process that spans a range of biomedical disciplines, including diagnostics, research, and forensics. While downstream analytical techniques have advanced in terms of both capability and throughput, analyte isolation technology has lagged behind, increasingly becoming the bottleneck in these processes. Thus, there exists a need for simple, fast, and easy to integrate analyte separation protocols to alleviate this bottleneck. Recently, a new class of technologies has emerged that leverages the movement of paramagnetic particle (PMP)-bound analytes through phase barriers to achieve a high efficiency separation in a single or a few steps. Specifically, the passage of a PMP/analyte aggregate through a phase interface (aqueous/air in this case) acts to efficiently “exclude” unbound (contaminant) material from PMP-bound analytes with higher efficiency than traditional washing-based solid-phase extraction (SPE) protocols (i.e., bind, wash several times, elute). Here, we describe for the first time a new type of “exclusion-based” sample preparation, which we term “AirJump”. Upon realizing that much of the contaminant carryover stems from interactions with the sample vessel surface (e.g., pipetting residue, wetting), we aim to eliminate the influence of that factor. Thus, AirJump isolates PMP-bound analyte by “jumping” analyte directly out of a free liquid/air interface. Through careful characterization, we have demonstrated the validity of AirJump isolation through comparison to traditional washing-based isolations. Additionally, we have confirmed the suitability of AirJump in three important independent biological isolations, including protein immunoprecipitation, viral RNA isolation, and cell culture gene expression analysis. Taken together, these data sets demonstrate that AirJump performs efficiently, with high analyte yield, high purity, no cross contamination, rapid time-to-isolation, and excellent reproducibility.

The Nanomaterial Data Curation Initiative: A collaborative approach to assessing, evaluating, and advancing the state of the field.

The Nanomaterial Data Curation Initiative (NDCI), a project of the National Cancer Informatics Program Nanotechnology Working Group (NCIP NanoWG), explores the critical aspect of data curation within the development of informatics approaches to understanding nanomaterial behavior. Data repositories and tools for integrating and interrogating complex nanomaterial datasets are gaining widespread interest, with multiple projects now appearing in the US and the EU. Even in these early stages of development, a single common aspect shared across all nanoinformatics resources is that data must be curated into them. Through exploration of sub-topics related to all activities necessary to enable, execute, and improve the curation process, the NDCI will provide a substantive analysis of nanomaterial data curation itself, as well as a platform for multiple other important discussions to advance the field of nanoinformatics. This article outlines the NDCI project and lays the foundation for a series of papers on nanomaterial data curation. The NDCI purpose is to: 1) present and evaluate the current state of nanomaterial data curation across the field on multiple specific data curation topics, 2) propose ways to leverage and advance progress for both individual efforts and the nanomaterial data community as a whole, and 3) provide opportunities for similar publication series on the details of the interactive needs and workflows of data customers, data creators, and data analysts. Initial responses from stakeholder liaisons throughout the nanoinformatics community reveal a shared view that it will be critical to focus on integration of datasets with specific orientation toward the purposes for which the individual resources were created, as well as the purpose for integrating multiple resources. Early acknowledgement and undertaking of complex topics such as uncertainty, reproducibility, and interoperability is proposed as an important path to addressing key challenges within the nanomaterial community, such as reducing collateral negative impacts and decreasing the time from development to market for this new class of technologies.

Mobile Health News & Products

Mobile Health News & Products

Challenges of Biomimetic Infochemical Communication

The natural world abounds with chemical information. Animals rely on chemical communication for behaviors as diverse as finding mates, locating food sources, or avoiding predators. Insects, in particular, are capable of incredibly precise chemocommunication using low-power signaling and processing systems. Most species rely on several compounds to convey specific information, establishing a diverse palette for chemical communication. This complex form of information exchange mediated by chemicals represents an unexplored form of communication and labeling technology that has yet to be exploited. In an attempt to mimic chemocommunication in the insect world, we have developed a new class of technology based on the infochemical communication of moths. We describe how this new class of technology could be realized by combining the latest advances and convergence of expertise in the fields of pheromone biochemistry, entomology, genetics, biophysics, materials science and neuroscience. The principles of signal biosynthesis and molecular detection in olfactory receptors and the central nervous system of insects are discussed. We then describe the technological aspects of implementing a microsystem capable of producing biosynthetic compounds as well as the development of a detector unit comprising a biological cell coating expressing specific ligand receptors and coupled to an acousto-electric transducer.

Towards a biosynthetic infochemical communication system

By exploiting recent advances in the understanding of both pheromone biosynthesis pathways and the detection of molecules in the insect nervous system, we are developing a new class of technology for biosynthetic infochemical communication. Here we present a prototype instrument that comprises an integrated chemotransmitter, an odour pathway and a chemoreceiver controlled by a laptop computer. Our initial studies show that the system can transmit, receive and decode a set of volatiles commonly found in fruits. The system is capable of ratiometrically encoding information by releasing complex blends of compounds in specific ratios, detecting the transmitted blends with a sensor array and decoding the infochemical information using neuromorphic algorithms representing ratio processing in the macroglomerular complex (MGC) of the antennal lobe of the moth (e.g. Manduca sexta).

Interspinous Process Spacers

The patient with neurogenic claudication resulting from lumbar spinal stenosis who fails to experience satisfactory relief from nonsurgical measures has limited treatment options. Lumbar epidural steroid injections and surgical laminectomy are generally accepted alternatives for the patient with moderate to severe symptoms. Interspinous process spacers, a relatively new class of technology, are proposed for use in the patient who prefers less invasive surgery or in whom medical comorbidities preclude a major surgical procedure. Early data from biomechanical and clinical studies support the short-term efficacy of interspinous process spacers in treating claudication related to spinal stenosis. Sufficient medium- and long-term data are lacking, however, particularly with respect to durability of symptomatic relief and the risk of device migration or dislocation. Although interspinous process spacers are a promising new technology, the results of longer-term clinical follow-up studies are needed to more clearly define their role in the management of lumbar spinal stenosis.

The BION devices: injectable interfaces with peripheral nerves and muscles

The purpose of this study was to describe a novel technology for implantable neuromuscular stimulation to treat complications of paralysis and disuse atrophy, including shoulder subluxation, hand contractures, drop foot, and osteoarthritis. The authors review the results so far of several pilot clinical studies of these muscle stimulation devices. Miniature wireless stimulators received power and individually addressed command signals from an external radiofrequency transmission coil. One or more implants were injected through a 12-gauge hypodermic insertion tool into muscles or adjacent to motor nerves, where they provided the means to activate the muscles in any desired pattern of intensity and frequency. Randomized controlled studies in small numbers of patients are underway to identify efficacy, acceptability, best methods of practice, and any design changes that may be required to improve the technology. Fifty patients have been enrolled in five studies; 35 patients have undergone implantation of a total of 79 BION1 devices. Comparisons with surface stimulation in patients who have suffered a stroke with shoulder subluxation and hand contractures show similar improvements in objective measures of efficacy but higher comfort levels for stimulation by implants. Injected microstimulators represent a promising new class of technology for the rehabilitation of patients with upper motor neuropathies. As the technology evolves, practitioners may be able to use it to facilitate functional reanimation of paralyzed limbs.

Beyond the handset

Service-based wireless devices like wireless telephones require users to interact with aspects of the technology beyond the hardware and software of the handset. By entering into contractual relationships with service-providers, and by using network-based services, users interact with a larger system ---one that has social and technological components. The operation of the wireless telephone requires the assimilation of heterogeneous sources of information from the device manufacturer, sales people, customer service representatives, marketing people, and members of the popular media, among others, which can easily confound users' understanding of this new class of technology. Opportunities for usability problems therefore scale beyond the handset, as do opportunities for better design. We report the results of a study of 19 novice wireless phone users who were closely tracked for the first 6 weeks after service acquisition. Taking a technology-as-system analytical approach, we describe the wireless telephony system as four socio-technical components: hardware, software, "netware," and "bizware." This particular organization of the system is intended for the practical application of designing for usability.

A class of hybrid intelligent system for fault diagnosis in electric power systems

In recent years, significant progress has been achieved in the development of a class of artificial intelligent systems. This growing new class of technology has been applied successfully to a wide variety of applications. It is now becoming increasingly evident that in many cases best results can be obtained through the use of combination of such intelligent systems. In this paper, a class of hybrid intelligent systems has been applied in diagnosing a variety of faults in a range of electric power system equipments. The nature of the faults are diverse and no single intelligent algorithm is able to classify the faults. However, it is shown, in this paper, that a combinatorial intelligent system based on neuro-fuzzy, neuro-expert and fuzzy-expert algorithms can be successfully applied in the detection of a number of faults in a range of equipments. Test results using measurements on in-service power transformers in the Australian state of New South Wales and on a distribution feeder belonging to CEMIG, Brazil have been used to show the effectiveness of the proposed class of hybrid intelligent systems in equipment fault diagnosis.