Rewarding Research Articles

Two-year trajectories of anhedonia in adolescents at transdiagnostic risk for severe mental illness: Association with clinical symptoms and brain-symptom links.

Anhedonia emerges during adolescence and is characteristic of severe mental illness (SMI). To understand how anhedonia emerges, changes with time, and relates with other symptoms, there is a need to understand patterns of this symptom's course reflecting change or stability-and associations with clinical symptoms and neural reward circuitry in adolescents at risk of SMI. In total, 113 adolescents at low or high familial risk of developing SMI completed clinical measures at up to five time points across 2 years and functional magnetic resonance imaging scanning during a guessing reward task at baseline. Growth curve analysis was used to determine the trajectory of anhedonia across 2 years, including different phases (consummatory and anticipatory) and their association with clinical features (risk status, average suicidal ideation, and average depression across time) and neural activation in response to rewards (ventral striatum and dorsal medial prefrontal cortex). The findings revealed anhedonia decreased across 2 years. Furthermore, lower depression severity was associated with decreases in anhedonia across 2 years. There were no interactions between neural reward activation and anhedonia slopes in predicting clinical features. Exploratory analyses examining latent classes revealed three trajectory classes of anhedonia across phases. While preliminary, in the low and decreasing consummatory anhedonia trajectory class, there was a positive association between neural activation of the right ventral striatum in response to rewards and depression. Certain patterns of anhedonia development could confer risk or resilience for specific types of psychopathologies. The results are preliminary but do highlight the complexity and heterogeneity in anhedonia development. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Technology rhetoric and institutional ownership

Abstract This article compares actual R&D spend with the managerial rhetoric around technology and innovation contained within corporate disclosures of US-listed firms. We find that, whilst actual R&D spend and patents do not entice institutional investors to increase their stock holdings, firms that espouse technology and innovation in their corporate disclosures are quite successful in drawing in short-term investors. We frame this investor behaviour within the economics of expectation literature. While managers are incentivised to draw in capital, short-horizon investors are less likely to exert due diligence and are rather persuaded by a technology narrative—that is, a ‘gold rush’ effect. This explains our finding that when there is a sudden downturn with stock price crashes, short-term investors rush to withdraw their money from firms that ‘talk tech’. Our findings have implications for managerial rewards systems, especially when these encourage managerial hype.

Motivation towards physical activities among Malaysian population by gender and age group

Sports culture among Malaysia Population still lacking and the percentage of inactive people still high and increase since year 2018. The aim of this study is to determine the level and influence of motivation towards physical activities based on gender and age groups. The researchers employed a survey design involving 7,015 respondents aged 13 years and above. Sampling selection across Malaysia was facilitated by Department of Statistic Malaysia based on block calculation and residence area from 13 states and 3 Federal Territories. The researcher employed the Multistage Cluster sampling random strategy by combining the cluster sampling procedure with stratified random sampling. A questionnaire designed by IYRES with high validity (r = 0.95) and reliability (r = .96) employed for data collection. A total of 190 trained enumerators collects the data manually. The findings of the analysis through an independent sample t-test showed that mean score for Males (M = 31.94, SD = 10.70) and for females (M = 29.84, SD = 10.82). p = .000, is significant. The results showed that there were significant differences in the mean of motivation towards physical activity participation between male and female respondents. Comparison by age group using One-way ANOVA showed that there were significant differences in the motivation of involvement in physical activity between the age groups, p = 0.000. Group pre-youth (M = 30.39, SD = 9.56), youth (M = 32.78, SD = 10.06), post youth (M = 30.72, SD = 11.06) and senior citizen 60 years and above (M = 26.76, SD = 10.72). This outcome proves that age does influence motivational factors in physical activity participation. The motivation level among youth is the highest and the elderly above 60 years old the lowest. Motivational factors are influenced by gender and age group in complex ways. Women tend to be more motivated by intrinsic factors such as job satisfaction, relationships, and personal growth, while men often lean towards extrinsic rewards. Younger individuals may be more driven by extrinsic rewards such as prizes, recognition, free gifts and performance achievements. Overall, psychological factors play a critical role in shaping individuals’ attitudes, beliefs, motivations, and behaviors regarding physical activity. By addressing psychological barriers and leveraging motivational strategies, interventions can effectively promote participation in exercise and support individuals in adopting healthier and more active lifestyles.

Food choice and neural reward systems in adolescents with anorexia nervosa and atypical anorexia nervosa.

Adolescence is a critical developmental period for the study of anorexia nervosa (AN), an illness characterized by extreme restriction of food intake. The maturation of the reward system during adolescence combined with recent neurobiological models of AN led to the hypothesis that early on in illness, restrictive food choices would be associated with activity in nucleus accumbens reward regions, rather than caudate regions identified among adults with AN. Healthy adolescents (HC, n = 41) and adolescents with AN or atypical AN (atypAN, n = 76) completed a Food Choice Task during fMRI scanning. Selection of high-fat foods and choice-related activation in nucleus accumbens and anterior caudate regions-of-interest (ROIs) were compared between individuals with AN/atypAN and HC. Associations were examined between choice-related activation and choice preferences among the AN group. Exploratory analyses examined associations between choice-related activation and psychological assessments among the patient group. Adolescents with AN or atypAN selected fewer high-fat foods than HC (t = -5.92, p < .001). Counter to predictions, there were no significant group differences in choice-related activation in the ROIs. Among individuals with AN or atypAN, choice-related neural activity in the anterior caudate was significantly negatively associated with high-fat food selections in the task (r = -.32, p = .024). In exploratory analyses, choice-related anterior caudate activation was positively associated with psychological measures of illness severity among patients (p's < .05, uncorrected). In this large cohort of adolescents with AN/atypAN, there was no evidence of altered reward system engagement during food choice. While there was no group difference in choice-related caudate activation, the associations with choices and psychological measures continue to suggest that this neural region is implicated in illness. Longitudinal analyses will clarify whether neural variability relates to longer-term course.

Developing a three-strand approach to playfulness in learning development

In this presentation, we outlined the development of a new Academic Skills Service at Oxford International Education Group, which, whilst supporting students from seven university-based international colleges, implemented a three-strand approach to playfulness in learning development. The presentation focused on three examples of playful approaches: The use of digital and traditional game-based learning within otherwise performance-driven classes. The creation of playful spaces in the form of extracurricular cross-college book and Maths movies clubs. The development of a gamified Moodle learning system through activity badging and levelling up. These initiatives reflect current research regarding the value of playful approaches in student learning and in counterbalancing a predominantly performance-driven higher education environment (Langan and Smart, 2018; Whitton, 2018; Forbes, 2021). Firstly, game-based learning can increase student enjoyment, motivation, and participation in the learning process and promote social belonging (James and Nerantzi, 2019; Forbes, 2021). Secondly, online book/Maths clubs can operate as playful spaces where student learning is supported in a positive social environment and creativity and risk-taking become part of the learning process (Whitton, 2018; James and Nerantzi, 2019; Forbes, 2021). Thirdly, although the gamified Moodle learning system relies on extrinsic rewards, which reflect the performance-led ethos of HE (Nørgård, Toft-Nielsen and Whitton, 2017), it can also increase student motivation in completing learning activities. This presentation proposed that learning development departments, whilst supporting student outcomes and the student experience, may encounter fewer performance-led constraints compared with programme-based delivery, enabling the utilisation of playful approaches that are otherwise underused in HE.

An Analysis of Critical Processes and Employee Challenges at Velmurugan Heavy Engineering Industries (VHEI) Private Limited, Thanjavur

This study investigates the critical processes and challenges faced by employees at Velmurugan Heavy Engineering Pvt. Ltd., located in Sengipatti, Thanjavur. The aim is to identify areas for improvement and provide recommendations to enhance employee performance and organizational effectiveness. Employing a mixed-method approach combining qualitative and quantitative methods, data were collected extensively through surveys, interviews, and observations from a representative sample across departments and hierarchical levels. The findings highlight critical areas such as project management, quality control, communication channels, and performance evaluation. While the organization demonstrates competence in these areas, gaps exist, particularly in streamlined communication and efficient project management. The study also uncovers challenges including unclear role expectations, limited professional development opportunities, inadequate work-life balance, and insufficient recognition and rewards. Recommendations are offered to strengthen communication channels, enhance project management practices, implement employee development programs, promote work-life balance initiatives, and establish a robust recognition and rewards system. Addressing these challenges and implementing recommended strategies has led to improved employee satisfaction, productivity, and overall organizational performance. This study provides valuable insights for Velmurugan Heavy Engineering Pvt. Ltd. to cultivate a positive work environment and foster a highly engaged workforce, contributing to sustainable growth and success

Reinforcement Learning for EV Fleet Smart Charging with On-Site Renewable Energy Sources

In 2020, the transportation sector was the second largest source of carbon emissions in the UK and in Newcastle upon Tyne, responsible for about 33% of total emissions. To support the UK’s target of reaching net zero emissions by 2050, electric vehicles (EVs) are pivotal in advancing carbon-neutral road transportation. Optimal EV charging requires a better understanding of the unpredictable output from on-site renewable energy sources (ORES). This paper proposes an integrated EV fleet charging schedule with a proximal policy optimization method based on a framework for deep reinforcement learning. For the design of the reinforcement learning environment, mathematical models of wind and solar power generation are created. In addition, the multivariate Gaussian distributions derived from historical weather and EV fleet charging data are utilized to simulate weather and charging demand uncertainty in order to create large datasets for training the model. The optimization problem is expressed as a Markov decision process (MDP) with operational constraints. For training artificial neural networks (ANNs) through successive transition simulations, a proximal policy optimization (PPO) approach is devised. The optimization approach is deployed and evaluated on a real-world scenario comprised of council EV fleet charging data from Leicester, UK. The results show that due to the design of the rewards function and system limitations, the charging action is biased towards the time of day when renewable energy output is maximum (midday). The charging decision by reinforcement learning improves the utilization of renewable energy by 2–4% compared to the random charging policy and the priority charging policy. This study contributes to the reduction in battery charging and discharging, electricity sold to the grid to create benefits and the reduction in carbon emissions.

EEG-Characteristics of Aesthetic Perception and Evaluation of Artworks During a Museum Visit: А Neuroaesthetic Study

Twenty-eight people (30–70 years old, 12 men, 16 women, artists and non-artists) participated in a comparative neuroaesthetic study in the conditions of real-life visit to M. Vrubel mono-exhibition (Russian Museum, St. Petersburg). During the visit to the exhibition (usually lasted for around 60 min), EEG of participants was recorded. The subjects were looking at the paintings for 30 seconds to 3 min and evaluated the subjective aesthetic “attractiveness” of the paintings by a series of button presses (from 1 to 10). Were analyzed EEG spectral power in the α1 (8–10 Hz)-, α2 (10–13 Hz)-, β1 (13–18 Hz)-, β2 (13–30 Hz)-frequency bands during viewing the most famous Vrubel paintings (“Bogatyr”, “Swan Princess”, “Swan”, “Sitting Demon”, “Flying Demon”, “Pan”, etc.) and event-related EEG synchronization/desynchronization in relation to the subjective emotional and aesthetic evaluation of these paintings. Professional artists showed lower spectral power values in α1 (leads F3, C3, T4, Pz) and α2 (F3, Fz, F4, C3, Cz, C4, P3, Pz, P4)-frequency bands in frontal, central, and parietal regions. The artists were also found to have lower power values in β1,2-frequency bands in frontal (F3, F4, C3) regions and higher power values in occipital (O1, O2 – β1, β2) and posterior temporal (β2) cortical regions compared to the group of subjects with no special artistic education. Moreover, artists decision-making about the high emotional-aesthetic attractiveness of paintings was accompanied by an increase in event-related EEG synchronization for 11.5–27 Hz in frontal and central cortical areas over 580–360 ms before giving the response, compared to non-artists, whereas low emotional-aesthetic evaluation was characterized by 9–27 Hz EEG desynchronization, which started 60 ms before the giving the response and lasted up to 440 ms after it, in the posterior temporal and parietal regions. The differences in frontal cortical areas may indicate a higher engagement of the reward system during the perception of aesthetically pleasing paintings, and the differences in parietal and posterior temporal areas may indicate a continuing visual synthesis (more sustained visual attention) during the perception of subjectively less attractive paintings in artists compared to non-artists.

Stimulation of Dopamine D4 Receptors in the Nucleus Accumbens Shell Increases Palatable Food Intake in Satiated Male Rats: Modulation by NMDA and AMPA Receptors

Background/Objectives: Palatability significantly influences food consumption, often leading to overeating and obesity by activating the brain’s reward systems. The nucleus accumbens (NAc) plays a central role in this process, modulating reward mechanisms primarily via dopamine through D2-like receptors (D2R, D3R, D4R). While the involvement of D2 receptors in feeding is well-documented, the role of D4 receptors (D4Rs) is less clear. Methods: Male Wistar rats received intra-NAc shell microinjections of the D4R agonist PD-168077 and the antagonist L-745870. This study also examined the modulation between D4R and glutamatergic transmission by administration of NMDA, NMDA receptor antagonist AP-5, AMPA, and AMPA receptor antagonist CNQX. Results: PD-168077 increased sweet solution intake by 46%, an effect that was reversed by L-745870. Pre-treatment with NMDA prevented the stimulatory effect of PD-168077, whereas the NMDA receptor antagonist AP-5 had no such effect. Additionally, AMPA administration reduced sweet solution intake by 63%, counteracting the effect of PD-168077, while the AMPA receptor antagonist CNQX, on its own, increased intake by 40%. Conclusions: These findings suggest that D4Rs promote hedonic feeding by modulating glutamatergic transmission in the NAc shell, highlighting the complexity of D4R involvement in food intake regulation. This study underscores the potential of targeting D4Rs for therapeutic interventions in eating disorders and obesity, though further research is essential to clarify the precise mechanisms through which D4R modulates AMPA and NMDA receptor activity in feeding behavior.

User preferences for an mHealth app to support HIV testing and pre-exposure prophylaxis uptake among men who have sex with men in Malaysia.

Recent estimates report a high incidence and prevalence of HIV among men who have sex with men (MSM) in Malaysia. Mobile apps are a promising and cost-effective intervention modality to reach stigmatized and hard-to-reach populations to link them to HIV prevention services (e.g., HIV testing, pre-exposure prophylaxis, PrEP). This study assessed attitudes and preferences toward the format, content, and features of a mobile app designed to increase HIV testing and PrEP uptake among Malaysian MSM. We conducted six online focus groups between August and September 2021 with 20 MSM and 16 stakeholders (e.g., doctors, nurses, pharmacists, and NGO staff) to query. Transcripts were analyzed in Dedoose software to identify thematic content. Key themes in terms of app functions related to stylistic preferences (e.g., design, user interface), engagement strategies (e.g., reward systems, reminders), recommendations for new functions (e.g., enhanced communication options via chat, discussion forum), cost of services (e.g., PrEP), and legal considerations concerning certain features (e.g., telehealth, patient identification), minimizing privacy and confidentiality risks. Our data suggest that a tailored HIV prevention app would be acceptable among MSM in Malaysia. The findings further provide detailed recommendations for successfully developing a mobile app to improve access to HIV prevention services (e.g., HIV testing, PrEP) for optimal use among MSM in Malaysia.

Developing Marketing Strategy for User-Generated Content: Study Case for Company X

This study investigates strategies to enhance user-generated content (UGC) growth for Company X, a part of Company X, to address the declining trend in UGC contributions and increasing operational costs. The study employs a qualitative methodology, including in-depth interviews with Company X users and content creators, to identify user personas, motivations, and preferences. External analyses such as PESTEL, competitive analysis, and internal SWOT analysis are used to frame the problem. The results suggest that enhancing the reward system, aligning incentives with user expectations, and improving platform engagement can increase UGC contributions. The proposed strategies aim to leverage UGC to reduce costs and boost user engagement and retention, supporting Company X’s future growth.

Exploring the Relationship between Reward Practices and Employee Engagement among County Governments in North Rift Region, Kenya

County governments in Kenya have not had systematic practices of employee engagement. The few that did adopt these practices did so in an isolated, informal, and uncoordinated manner, which was unlikely to yield any meaningful results. Effective human resource practices can have a significant impact on employee engagement. Low employee engagement can result in various issues, including high employee turnover, low productivity, and reduced organizational effectiveness. This study sought to establish the effect of employee reward practices on employee engagement among selected county governments in the North Rift Region, Kenya. The study was anchored on Human Capital Theory. The target population comprised 10,009 employees working in three North Rift counties comprising of Elgeyo Marakwet, Uasin Gishu, and Nandi Counties. The target population was made up of 2,611 employees from Elgeyo Marakwet County, 3,164 employees from Uasin Gishu County, and 4,234 employees from Nandi County. Cluster and simple random sampling techniques were used to select the 385 employees. The data was collected using structured questionnaires. A pilot study was conducted to examine the validity and reliability of the research instrument. Quantitative data from the closed-ended questions was analyzed using descriptive statistics. The study used descriptive statistics, including mean, frequencies, percentages, and standard deviation, to assess respondents' levels of agreement with the statements in the questionnaire. Furthermore, regression analysis was conducted to establish the relationship between employee reward practices and employee engagement. The results were presented using tables. The findings revealed that the model was significant in explaining the relationship between employee reward practices and engagement (F = 142.299, p = 0.000). The study also found that employee reward practices (B=0.358, p&lt;0.001) had positive and significant effect on employee engagement. Consequently, the study recommends that County governments should focus on revising and strengthening their reward practices to ensure fairness and competitiveness. Additionally, the managements of the three counties should develop competitive and equitable reward systems that recognize and reward employees' contributions effectively. Keywords: Reward Practices, Employee Engagement, Public Sector Motivation, County Governments, North Rift Region

The influence of emotional intelligence and employee motivation on employee performance in telecommunication companies in the sultanate of Oman

This study examines the impact of emotional intelligence (EI) and employee motivation on employee performance within the telecommunication industry in the Sultanate of Oman. The target population consisted of 4344 non-managerial employees across nine telecommunication companies, including Omantel, Ooredoo, Vodafone, Oman Broadband Company, Awasr Oman &amp; Co, TEO, Oman Tower Company L.L.C, Helios Tower, and Connect Arabia International. Employing a deductive research approach, finally data were collected via an online survey from 354 respondents. The hypotheses were tested using multiple regression analysis. The results indicate that all dimensions of EI self-awareness, self-regulation, empathy, and social skills positively and significantly influence employee performance, with social skills having the strongest effect. Furthermore, both intrinsic motivation factors, such as work itself and career development, and extrinsic motivation factors, including wages, rewards, working environment, and co-worker relationships, significantly enhance employee performance. The interaction between EI and employee motivation was found to amplify these positive effects. Among control variables, age and education level showed significant impacts, while gender did not. These findings underscore the critical role of both emotional intelligence and motivation in driving employee performance. The study suggests that managers and policymakers should adopt integrated strategies that develop EI competencies and enhance motivational factors to optimize employee performance, thereby contributing to the success of organizations in the telecommunication sector.

Locating Values in the Space of Possibilities

Abstract Where do values live in thought? A straightforward answer is that we (or our brains) make decisions using explicit value representations which are our values. Recent work applying reinforcement learning to decision-making and planning suggests that, more specifically, we may represent both the instrumental expected value of actions as well as the intrinsic reward of outcomes. In this paper, I argue that identifying value with either of these representations is incomplete. For agents such as humans and other animals, there is another place where reward can be located in thought: the division of the space of possibilities or “state space.”

Connectomics Investigation of Role of Parabrachial Nucleus Aversion using Optogenetics: A Experiment Proposal

In recent decades, there has been a notable increase in research activity focused on the aversive and reward circuits of the brain. The evidence indicates that the parabrachial nucleus (PBn) is a crucial element in the generation of aversion responses in mice. Following successful stimulation of the PBn, mice display increased aversive and stress-related ehaviours. The study employs Fos TRAP2-ChR2 mice, opioids such as oxycodone, and a range of imaging technologies to monitor and manipulate neural pathways. Behavioral tests and optogenetic manipulation are used to assess real-time behavioral responses in mice, with the aim of uncovering the neural pathways and mechanisms involved in PBn-mediated aversion. Nevertheless, the underlying mechanisms of these behaviours remain unclear. The objective of this study is to investigate the connectomics of the parabrachial nucleus (PBn) in order to determine its association with regions involved in motivation, such as the nucleus ambiguus or the amygdala. It is hypothesised that this association may lead to aversion by affecting these regions. An alternative hypothesis is that if the parabrachial nucleus is connected to areas that are not directly related to it, it may be considered a motivational area in its own right. The identification of these connections will elucidate the underlying mechanisms of aversion mediated by PBn, thereby providing a deeper understanding of the neural basis of aversive behaviour and its regulation.

Exploring distinct and joint contributions of the locus coeruleus and the substantia nigra/ventral tegmental area complex to reward and valence processing using high-resolution fMRI

Abstract Dopaminergic neurons in the substantia nigra and the ventral tegmental area (SN/VTA) are classically viewed as key mediators in reward processing, while noradrenergic cells in the locus coeruleus (LC) are thought to modulate (negative) saliency processing. However, this conventional distinction is being revised by more recent research in animals. To explore the respective contributions of both the LC and SN/VTA in reward and valence processing in humans, we assessed fMRI data during stimulus encoding and response phase of a rewarded emotion-discrimination task (n = 38). Participants responded significantly faster to reward predicting and negative valence stimuli compared with their non-salient counterparts. LC activity was overall higher during trials involving reward prospect, and in particular for reward trials featuring positive valence, demonstrating an additive effect of reward and positive valence in LC. Moreover, LC activity was differentially increased for negative compared with positive valence in the response phase, indexing its role in invigorating responses to negative events. The SN/VTA showed increased activity in the response phase of reward trials (neutral valence) and negative valence trials (no reward), which aligns with coding relative saliency of these events in their respective contexts. LC modulations were accompanied by covariations in occipital cortex, suggesting noradrenergic contributions to visual prioritization of salient events. The findings underscore the sensitivity of both LC and SN/VTA to reward prospects and negative valence, challenging the dominant view of SN/VTA’s involvement in merely positive events and emphasizing their essential role in action invigoration above and beyond mere stimulus encoding. The intricate roles of the DA and NA system in reward and emotional valence processing in humans warrant further exploration and validation, given the limitations inherent to neuroimaging of deep brain structures.

Predictors of self-care behaviors in hypertensive patients based on the protection motivation theory

IntroductionGlobally, hypertension is a significant public health concern and a leading cause of premature death. Since this disease is incurable, it is necessary to promote patients’ self-care behaviors to control it. The goal of this research was to identify the elements that influence self-care actions in individuals with hypertension, utilizing the Protection Motivation Theory (PMT) framework.MethodsA study was carried out in Omidiyeh, located in southern Iran, using a cross-sectional design, involving 397 adults with hypertension (198 females and 199 males) who were selected from comprehensive health centers using a stratified random sampling technique. Data was gathered through a demographic data collection form and a questionnaire created by the researcher, which was based on the PMT. Data were assessed utilizing SPSS 25 and AMOS 24 software, and various statistical tests including one-way ANOVA, Pearson correlation, multiple regression, independent t-test, and structural equation modeling were conducted.FindingsThe variables of intrinsic reward (r = 0.182), extrinsic reward (r = 0.288), and response cost (r = 0.126) showed a significant negative correlation with self-care behaviors. On the other hand, perceived susceptibility (r = 0.212), perceived severity (r = 0.110), self-efficacy (r = 0.555), and response efficacy (r = 0.424) demonstrated a significant positive correlation with self-care behaviors. Specifically, self-efficacy and response efficacy were the most powerful predictors of self-care behaviors, respectively.ConclusionThe results showed that several factors can forecast self-care behaviors in patients with hypertension. Researchers are recommended to incorporate PMT in educational interventions and concentrate on self-efficacy and response efficacy constructs.

Reward system activation improves recovery from acute myocardial infarction

Abstract Introduction Psychological processes play a crucial role in the recovery from acute myocardial infarction (AMI), yet the underlying mechanisms of these effects remain elusive. Here, we focused on the reward system, which mediates positively valenced emotions, motivation, and expectation and is based mainly on dopaminergic neurotransmission from the ventral tegmental area (VTA). Purpose The study examines the impact of activating dopaminergic neurons in the VTA following AMI in mice, aiming to understand the extent and mechanisms through which motivational brain network contribute to cardiac recovery process. Methods We used Designer Receptor Exclusively Activated by Designer Drugs (DREADDs) to target neuronal activity. We performed an AMI model and assessed cardiac function using cardiac magnetic resonance (CMR). We used histology, immunohistochemistry, proteomic analysis, ELISA, reverse transcription-PCR, endothelial tube formation assay, and pseudorabies-virus neuronal tracing to investigate the mechanism. Results Chemogenetic activation of dopaminergic neurons in the VTA significantly modified the remodeling processes by reducing scar tissue (Fig. 1a) and increased vascularization (Fig. 1b) 15 days following AMI, leading to improved left-ventricular performance compared to control (Fig. 1c). These effects were mediated through several physiological mechanisms, including alterations in immune activity, and reduced adrenergic inputs to the liver. We further demonstrate an anatomical connection between the VTA and the liver that follows AMI manifested by altered transcription of complement component 3 (C3). We established the essential role of C3 in endothelial tube formation in vitro and its necessity in the beneficial effects of VTA activation on the recovery from AMI in vivo (Fig.2). Conclusion These findings establish a causal connection between a motivational brain network and recovery from AMI, introducing potential new therapeutic avenues for intervention.Effects of VTA activation on cardiac recMechanism of VTA effects

The Impact of Financial and Non-Financial Rewards on Employee Migration Intentions in Lagos Banking Sector

The Nigerian banking sector has been facing a significant exodus of skilled employees in recent times which has continued to threaten the sector's development. However, despite numerous studies to address this phenomenon, fewer empirical studies have explored how financial and non-financial rewards impact the migration intention of employees in the banking sector in Nigeria. This study therefore examines how reward systems including financial and non-financial affect the migration intention of employees in Lagos banking sector. A cross-sectional design with purposive and proportionate sampling was adopted for the study. The purposive sampling was adopted to select eight banks in the Mainland Local Government Area of Lagos, Nigeria while a proportionate sampling was used to sample the respondents to ensure adequate representation across the banks. A structured questionnaire was used for collecting data from a sample size of 99 which was determined from a population of 131 in the selected banks using the Yamane formula. However, only 89 responses were obtained across the selected banks and were then statistically analysed using descriptive statistics for the socio-demographic data. Correlation with multiple regressions was utilised for hypothesis testing at a 5% significance level and the study found that both financial and non-financial rewards significantly affect employees’ migration intention. Therefore, the management of banks should improve on the existing financial reward systems to make them more globally competitive as this would enhance talented employees’ retention and reduce employees’ migration intention in the banks.

Teacher Performance in the 21st Century: Examining the Roles of Leadership, Self-Efficacy, Compensation, and Job Satisfaction

The main purpose of this study is to examine the effect of leadership on teacher performance via self-efficacy and job satisfaction, a mediating variable, as well as compensation. Based upon an Indonesia study, the research engages a meta-analysis of these relationships for illuminating insights on optimizing teacher performance in educational environments. We collected data from a sample of 680 teachers 87% response rate and analyzed them using SmartPLS, the evaluation comparable to complex social science models. The results suggest that both self-efficacy and compensation affect teacher performance directly, respectively, through job satisfaction; principal leadership only has a significant direct effect on the dependent variable without being mediated by job satisfaction. These results may have implications for how intrinsic and extrinsic factors, motivation, rewards, and leadership styles influence faculty outcomes. The practical implications include a call for targeted teacher professional development and compensation policies that are more equitable and effective educational leadership practices to improve teaching performances, which will in turn favorably impact the quality of education generally.