Induction motor drives with variable speed applications that employ vector control are quite popular nowadays because they provide strong dynamic performance and flexible speed control. By decoupling the torque-producing current components of stator current from the rotor flux, Indirect Field Oriented Control is recognized for generating excellent performance in induction motor drives. This investigation is being done to show the effectiveness of the novel FPI input-output data-trained ANFIS controller and compare the three controllers' performance in terms of load variation capabilities, motor parameter variation, and speed tracking. Consequently, a comparison of the three controllers is important to select which controller performs high in induction motor drive. Indirect Field Oriented Control of induction motor with Fractional Proportional Integral (FPI), Integer Proportional Integral (IPI), and Adaptive Neuro-Fuzzy Inference System (ANFIS) controllers are all discussed in this work along with their designs and comparative analysis. The square of error was used as a fitness function to genetically optimize the FPI and IPI controller parameters. The suggested Adaptive Neuro-Fuzzy Inference System (ANFIS) controller uses a hybrid learning approach. It is trained by the FPI controller's input-output data. Using the results of MATLAB simulations under various operating situations, the performance of the ANFIS controller was compared with FPI and IPI controllers. Because of FPI controller includes an extra parameter for adjustment, namely integration order, it performed better than IPI controller for speed control of the induction motor. According to the simulation findings, the percentage peak overshoots while employing ANFIS, FPI, and IPI controllers were 0.495 %, 12.062 %, and 14.699 % respectively. As a result, ANFIS exhibits a drastic reduction in overshoot. Additionally, with the ANFIS controlled induction motor drive, the speed achieves the required set value at 0.14 s. For no load, constant, and changing loads, the induction motor drive's performance has been examined.