Two field campaigns in Dafeng and Jianggang were organized to compare spatial variations of hydrodynamic characteristics and sediment transport patterns on intertidal flats of different types with distinct human interferences along middle Jiangsu coast, China. The major contributors to the different patterns of sediment dynamics between the two tidal flats were offshore tidal current field and human interference. Offshore tidal force provide the basic setup of tidal current patterns on tidal flats, which is then modified by local morphology. Seawalls parallel to coast reduce tidal flat width, forcing tidal energy to dissipate within a shorter distance and thus influencing tidal flat morphology. Seawalls vertical to coast and major tidal current significantly reduce tidal current speed, which favors sediment deposition on tidal flats. Two seawalls built on both sides of the observational tidal flat profile caused much reduced current speed at Dafeng tidal flat, comparing to the offshore station. Being exposed to offshore radial tidal currents, hydrodynamics at Jianggang was much stronger than that at Dafeng. Residual currents at both areas showed net landward transport at the lower flat and net seaward transport at the upper flat, in favor to sediment accumulation at the middle flat. Sediment flux over tidal cycles showed net landward sediment transport at Dafeng, and net seaward transport at Jianggang, consistent with the convex-up accretion-dominated profile observed at Dafenge, and concave-up erosion-dominated profile observed at Jianggang. The instantaneons sediment flux changed significantly due to variations in velocity and sediment concentrations, but these terms counteracted with each other within tidal cycles, leading to the dominant role of Eulerian flux in determining net sediment flux over tidal cycles.