Background: Bone tumours are comparatively uncommon among wide array of lesions and pose a diagnostic problem. Definitive clinical diagnosis of bone lesion is often difficult. So it is essential to identify the lesion correctly before deciding the line of treatment. For the correct diagnosis of bone lesions, charting out treatment plan and estimating prognosis, interpretation of biopsy material proves to be indispensable.
 Method:- This hospital based cross-sectional study conducted 50 histopathological reports and slides of patients who had bone tissue biopsies were reviewed to provide relevant information on age, sex, histopathological interpretation, and the anatomical site of occurrence.
 Results: Mean age of patients was 21.36±6.39 yrs and 58.00% patients were male. 62.00% patients belonged to rural area. 78.00% patients were benign and 22.00% patients were malignant.
 Conclusion: In our study, neoplastic bone lesions were more common than non-neoplastic bone lesions. Bone lesions were more common in younger age group.
 Keywords: Bone Tumours, Histopathology, Giant Cell Tumour, Osteosarcoma