Negative Pressure Isolation Rooms Research Articles

Effect of Infection Control Simulation Based on a Negative Pressure Isolation Room Using Mixed Reality.

This study aimed to examine the effectiveness of an infection control simulation using mixed reality, comparing simulation fidelity with a high-fidelity mannequin (MN) group and problem-based learning with written cases group. This study used a three-group pretest-posttest quasi-experimental design. Two universities with similar curricula were conveniently selected, and a total of 72 nursing students were recruited. Participants were randomly assigned to three groups of 24 each. In the final analysis, there were 22 participants in the mixed reality groups, 21 in the mannequin groups, and 23 in the problem-based learning with written cases groups. Data were analyzed using descriptive statistics and the χ 2 , Kruskal-Wallis, and Wilcoxon signed rank tests. The mixed reality groups had a significantly positive effect on clinical reasoning ability and clinical competence than the problem-based learning with written cases groups, whereas the mannequin groups had a significantly positive effect on clinical competence than the problem-based learning with written cases groups. Mixed reality simulation is an appropriate simulation method that enhances learning immersion, satisfaction, and self-confidence in simulation. Additionally, it can substitute for mannequin simulation in terms of clinical reasoning ability and clinical competence. This study suggests that it is important to the various approaches in simulation fidelity to diversely enhance the competency of nursing students in simulation outcomes.

긴급전환형 임시음압격리병실의 기밀성능과 형성 차압의 관계성 분석

긴급전환형 임시음압격리병실의 기밀성능과 형성 차압의 관계성 분석

Airflow and Pressure Design Review of Modular Negative Pressure Wards

In the aftermath of the COVID-19 pandemic, the urgent need for the rapid deployment of healthcare facilities propelled the rise of modular construction using an infill approach. In these modular, negative-pressure wards, the design of indoor airflow and pressure plays a crucial role in meeting the ventilation strategies required for isolation facilities. Accordingly, this paper focuses on modular negative-pressure wards employing an infill construction method and proposes an appropriate spatial pressure distribution to address the problem of air tightness degradation due to leakage. This study analyzed the indoor airflow and pressure distribution of a unit module corresponding to an infill. It aimed to examine whether the pressure difference with the adjacent room is maintained and to assess its effectiveness in isolating contaminated air. First, the airflow rate of the heating, ventilation, and air conditioning system in the unit module was calculated to ensure that it would meet the performance criteria of the negative-pressure ward. Afterward, based on the calculated rate, the study assessed the airflow and room-specific pressure within a typical floor, encompassing both the unit module and associated nursing support facilities. Here, the airflow in the external corridor of the typical floor was divided into two cases according to the pressure distribution: negative pressure and atmospheric pressure. The calculation results were compared using a computational fluid dynamics tool. The analysis results confirm that the air isolation performance is adequate as the pressure difference between adjacent rooms in the unit module and the typical floor was maintained at 2.5 Pa. Additionally, the indoor airflow in the negative-pressure isolation room formed a stable flow at a slow speed of 0.1–0.2 m/s, minimizing the possibility of air contamination from outside the isolation room. In particular, Case B of the typical floor design proposes a method to optimize the pressure distribution in the modular negative-pressure ward by designing the ventilation flow rate at atmospheric pressure level. Thus, this study emphasizes that atmospheric pressure design is appropriate when designing pressure in areas where negative-pressure control is difficult and can contribute to the design and improvement of similar medical facilities in the future.

Conversion of a regular patient room to negative pressure at Ancona university hospital (Italy). A combined experimental and numerical investigation

Negative pressure isolation rooms are employed to prevent the spread of infectious diseases to surrounding spaces. This study reports a combined experimental and numerical analysis aimed at reliably assessing the performance of hospital ventilation systems and effectively reducing the risk of airborne infections. The study appraises the enhancement of the safety conditions by retrofitting an existing, positive pressure room ventilation system with a negative pressure and recirculation one. The assessment consisted in experimental measurements of airborne particle concentration and Computational Fluid Dynamics (CFD) simulations with Lagrangian particle tracking of respiratory droplets. The ventilation performance improvement was quantified in terms of recovery rate, contaminant removal effectiveness, particle transfer toward adjacent spaces and probability of infection.Two experimental campaigns were carried out: an ISO standard recovery assessment and a test in real operational conditions. The negative pressure configuration significantly improved the safety inside the patient ward: the recovery rate for droplets with diameter larger than 5 μm increased by a factor three, and the contaminant removal effectiveness after 15 min increased from 45% to 81%. The numerical model for Computational Fluid Dynamics simulation was successfully validated, confirming the ability of the approach to reproduce the undergoing Physics. The negative pressure design eliminated the particle transmission to surrounding spaces, while 2.5% of the emitted respiratory droplets escaped the room in the original existing scenario. The probability of infection after 15 min exposure was reduced by a factor three and peak values reaching 15% were limited to the immediate vicinity of the patients.

Design of Immersive Information Simulation of Negative Pressure Isolation Room for Covid-19 Infection Patients Using Virtual Reality

This research aims to provide knowledge about how to create and the need for air circulation in negative pressure isolation rooms. If practiced directly, it will require large costs because it requires costs for procuring space and equipment. By using virtual reality (VR) technology, this problem can be solved because VR can provide an immersive environment like being in the real world. VR users will be able to experience how the requirements and how to create a negative pressure isolation room are like how it feels in the real world. So this can provide information and training on how to make a negative pressure isolation room before making an actual isolation room. Activities using VR will reduce the risk of errors and training costs on how to make an isolation room even without the cost of equipment. The purpose of this research is to provide convenience for health educators and the government on how to make negative pressure isolation rooms and the need for air circulation. So, it is enough to use VR technology, so the information on how to use VR is enough to make the isolation room and its needs work without having to use the right tools. This research method is descriptive and quantitative which begins with a literature review followed by an analysis of the need for isolation rooms and VR immersive environments. The implementation and testing process results in VR technology being able to help understand negative pressure isolation rooms for health workers.

Numerical Study of Three-Dimensional Flow in a Negative Pressure Isolation Room with One Inlet and Two Outlets Ventilation Configurations with Variations in Bed Positions and Variations in Outlets Pressure Differences

Numerical Study of Three-Dimensional Flow in a Negative Pressure Isolation Room with One Inlet and Two Outlets Ventilation Configurations with Variations in Bed Positions and Variations in Outlets Pressure Differences

A hybrid model to assess the risk of COVID-19 in hospital screening procedures under uncertain information

The large-scale outbreak of Coronavirus Disease 2019 (COVID-19) has spread rapidly since 2019 to various countries around the world, making “infection control” a topic of concern for governments, medical institutions, and the general population alike. This study proposes a risk assessment model based on a combination of Failure Mode and Effects Analysis (FMEA) and Multi-Criteria Decision-Making (MCDM) which can be applied to conduct a comprehensive risk analysis of the hospital disease screening process and explore the risk ranking issues. Faced with changes in the pandemic situation and high information uncertainty, this model uses Single Valued Trapezoidal Neutrosophic Sets (SVTNS) to integrate expert opinions and the Best-Worst Method (BWM) to find the risk factor weights. The SVTNS is then combined with the Reference Ideal Method (RIM) to calculate the ranking of risk modes and identify the priorities for improvement. The results show that “failure of physician judgment,” “inaccurate patient filling,” and “failure of negative pressure isolation room sterilization” are the three most risky failure modes in the screening and treatment process. This study addresses each of these high-risk failure modes and proposes recommendations for improvement so that decision-makers can prioritize improvements to reduce the incidence of hospital-acquired infections.

국가 감염병 대응을 위한 이동형 음압격리병실 개발 및 감염방지 환기성능 평가에 관한 연구

In this paper, we propose a mobile negative pressure isolation room to ensure the safety of healthcare workers (HCWs) and provide rapid medical service, and analyze the performance of a ventilation system that can minimize virus cross-contamination through numerical analysis. The negative pressure isolation room uses a ventilation system with air flowing from the HCWs to the patient, a clean-contaminated zone separation, and pressure differential control applied to the anteroom/isolation room. CFD) simulation results showed that the negative pressure isolation room, which needs to maintain negative pressure, can prevent cross-infection by using a ventilation system with a rate of 6 ACH and maintaining a pressure differential of -2.5 Pa or higher with the anteroom/corridor, regardless of toilet exhaust operation. It is recommended to operate the toilet exhaust at all times to maintain the pressure differential in the existing hospital rooms. However, the independently configured mobile negative pressure isolation room operates efficiently even if the toilet exhaust fan is not in operation, making it a more energy and noise-efficient option.

Airflow distribution in hospital isolation rooms with different ventilation and exhaust vent configurations

Negative pressure isolation rooms can accommodate and treat patients with highly infectious diseases (such as COVID-19). Airtight conditions in the isolation room protect against infectious diseases. To control airflow and minimize infection risk within the isolation room, this study proposes three exhaust outlet vents with three air change per hour (ACH) conditions, 12, 24 and 48 ACH, in a single-bed hospital room using a computational fluid dynamics (CFD) approach. Results show that using the same ACH air velocity is relatively unaffected by the type and location of the exhaust air vent. The current case, case 1 and case 2 had average velocities of 0.121, 0.130 and 0.116, respectively. When the ACH was increased to 48, the average velocity was decreased to 0.663 m/s in case 1 and 0.589 m/s in case 2, compared to 0.711 m/s in the current case. In terms of infection probability, the study found that in the scenario of 12 ACH, the infection probability for case 1 and case 2 was increased by 11.85% and 3.96%, respectively, compared to the current case. The exhaust air vent in case 2 could effectively prevent the spread of pollutants when it was set to 48 air changes per hour and had the lowest risk level at 10.11%.

An Autonomous IoT-Based Contact Tracing Platform in a COVID-19 Patient Ward

Since 2020, the coronavirus disease (COVID-19) pandemic has had a substantial impact on all community sectors worldwide, particularly the health care sector. Healthcare workers (HCWs) are at risk of COVID-19 infection due to occupational exposure to infectious patients, visitors, and staff. Contact tracing of close physical interaction is an essential control measure, especially in hospitals, to prevent onward transmission during an outbreak event. In this article, we propose an IoT-based contact tracing system for subject identification, interaction tracking and data transmission in hospital wards. The system, based on Bluetooth Low Energy (BLE) devices, tracks the duration of interactions between different HCWs, and the time each HCW spends within the patient rooms using additional information from proximity sensors in the hallway or on the door frame of the patient room. The collected data are transferred via Long Range (LoRa) wireless technology and further analyzed to inform infection prevention activities. The suggested system’s performance is evaluated in a COVID-19 patient ward with both standard and negative pressure isolation rooms, and the current system’s capabilities and future research prospects are briefly discussed.

Onsite measurement and dilution-based infection risk assessment for a new mobile negative pressure isolation room (MNPIR) as a solution to minimize cross-infection

This study proposes an onsite measurement protocol and infection risk assessment using tracer gas tests based on the dilution-based method to evaluate the ventilation system's performance in the mobile negative pressure isolation room (MNPIR) and minimize infection risk for health care workers (HCW). The dilution-based infection risk assessment is better in determining spatial distribution of infection risk compared to the Wells-Riley model. The study shows that ventilation effectiveness to reduce the infection risk for HCWs can be reviewed using four onsite measurement protocols and a dilution-based infection risk assessment. Optimizing the SA and EA installation locations is key to reducing the cross-infection risk of HCWs, and the contaminant removal effectiveness (CRE) index averaged 2.6, indicating adequate ventilation efficiency. By applying an appropriate ventilation system, the infection risk in HCW spaces was reduced to 50% or less of the average risk (by the Wells-Riley model). The proposed approach allows for quantitative evaluation of infection risk by location and exposure time, demonstrating that the MNPIR can effectively minimize infection risk for HCWs. The study suggests follow-up research on cooling and heating strategies that consider both patient comfort and effective ventilation performance in the MNPIR.

Aerosol Concentrations During Otolaryngology Procedures in a Negative Pressure Isolation Room

To evaluate the role of a negative pressure room with a high-efficiency particulate air (HEPA) filtration system on reducing aerosol exposure in common otolaryngology procedures. Prospective quantification of aerosol generation. Tertiary care. The particle concentrations were measured at various times during tracheostomy tube changes with tracheostomy suctioning, nasal endoscopy with suctioning, and fiberoptic laryngoscopy (FOL), which included 5 times per procedurein a negative pressure isolation room with a HEPA filter and additional 5 times in a nonpressure-controlled room without a HEPA filter. The particle concentrations were measured from the baseline, during the procedure, and continued until 30 minutes after the procedure ended. The particle concentrations were compared to the baseline concentrations. The particle concentration significantly increased from the baseline during tracheostomy tube changes (mean difference [MD] 0.80 × 106 p/m3 , p = .01), tracheostomy suctioning (MD 0.78 × 106 p/m3 , p = .004), at 2 minutes (MD 1.29 × 106 p/m3 , p = .01), and 3 minutes (MD 1.3 × 106 p/m3 , p = .004) after suctioning. There were no significant differences in the mean particle concentrations among various time points during nasal endoscopy with suctioning and FOL neither in isolation nor nonpressure-controlled rooms. A negative pressure isolation room with a HEPA filter was revealed to be safe for medical personnel inside and outside the room. Tracheostomy tube change with tracheostomy suctioning required an isolation room because this procedure generated aerosol, while nasal endoscopy with suctioning and FOL did not. Aerosol generated in an isolation room was diminished to the baseline after 4 minutes.

Comparison of particles leakage with different types of masks using a coughing simulator in a negative pressure isolation room

Although the rate of wearing masks has increased to 97.9%, there is a possibility that a gap between mask and face may occur because it does not completely fit to face, or that the virus may spread due to the poor performance of the mask. Accordingly, many studies are being conducted to evaluate performance of masks, or to measure the flow rate of coughing with PIV (Particle Image Velocimetry). However, most of these studied the performance inside or on the surface of a mask, and research on particle emitting after wearing masks is insufficient. Therefore, in this study, the particle concentration leaked after wearing masks in the negative pressure isolation room experimental chamber was measured, using particle counters and low-cost sensors. A manikin was installed on a bed to release aerosols, and the tendency of particles to decrease after one cough was analyzed. As a result, most of the particles were removed within 10 minutes. The low-cost sensors and particle counters installed in the centre and right wall exhaust diffuser show that with N95 mask on, particles were removed the fastest, and with surgical mask on, particles leaked the most immediately after coughing and were removed the slowest.

The Relationship Between The Characteristics of COVID-19 Patients To Predict Mortality in The COVID-19 ICU Special Care

Introduction: The SARS-CoV-2 epidemic is sweeping the world with several waves of infections continuing. In some COVID-19 patients, this condition can develop into ARDS (acute respiratory distress syndrome) which requires ICU care with a mortality rate of 50-65 and the need for mechanical ventilation reaches 97%. The aim of this research was to know characteristics of COVID-19 patients to predict mortality in the Negative Pressure Isolation Room COVID 19 ICU at H. Adam Malik General Hospital Method: Retrospective research method with secondary data sources of COVID-19 Negative Pressure Isolation Room ICU (RITN) patients at RSUP H. Adam Malik Medan for the period May 2021 – July 2021.The data collected was in the form of patient data including name, gender, age, medical record number, comorbidities, NLR, D-Dimer, Fibrinogen, PF ratio, use of oxygen supplementation, and length of ICU stay. Chi Square statistical analysis was used for categorical data, while the T-test or Mann Whitney was used for numerical data. Then between the variables an ANOVA test was carried out to assess the comparison of clinical characteristics with mortality. Results: The results of this study indicate a higher mortality rate in women41 people (57.7%), 56-65 years age group 26 people (36.6%), patients using ventilators 51 people (71.8%), comorbid hypertension 33 people (46.5%) ), Moderate PF Ratio were 44 people (62%) and Length of stay <10 days were 55 people (77.5%). The mean fibrinogen value in COVID-19 patients who died was 658.96 ± 674.98, as well as the D-dimer value of 658.96 ± 674.98 and NLR of 11.06 ± 3.23 which showed a significant increase compared to patients Survivors of COVID-19 (p<0.05). Conclusion: A significant relationship was found between gender, age, breathing apparatus, D-dimer, Fibrinogen, NLR and length of stay with mortality of COVID-19 patients treated in the COVID Negative Pressure Room (RITN) ICU

293. Risk factors for COVID-19 associated pulmonary aspergillosis (CAPA) in severe COVID-19 and impact of airborne fungal contamination within negative pressure isolation room

Abstract Background COVID-19 increase the risk of invasive pulmonary aspergillosis. However, the risk factors and fungal origin of COVID-19 associated pulmonary aspergillosis (CAPA) is not fully defined yet. We aim to identify the risk factors for CAPA in severe COVID-19 and evaluate association between fungal contamination within the air of negative pressure rooms and diagnosis of CAPAs. Methods We performed a retrospective case-control study to identify risk factors for CAPA with 420 severe COVID-19 patients from March 2020 to January 2022 who admitted to a tertiary care hospital in South Korea. CAPA was defined with modified AspICU criteria. Control, matched by admission date and severity of COVID-19 at admission, was selected for each case. Air sampling and fungal culture was done on Jan 2022 with a microbial air sampler (MAS-100NT) at 11 spaces in the COVID-19 designated isolation ward including 9 negative pressure isolation rooms (IRs). A cross-sectional comparison between rooms with and without airborne fungal contamination was performed. Results A total of 420 COVID-19 patients were hospitalized during the study period, and 51 patients were diagnosed with CAPA (prevalence 12.14%, incidence 6.26 per 1000 patient•day). Multivariate analysis showed that older age (odds ratio [OR] 1.051, 95% confidence intervals [CI] 1.006-1.009, p=0.025), mechanical ventilator use (OR 2.692, 95% CI 1.049-6.911, p=0.04), and lymphopenia (OR 4.353, 95% CI 1.727-10.975, p=0.02) were independent risk factors for CAPA. (Table 1, 2) Aspergillus spp. was identified within the air from 7 out of 11 spaces including 6 IRs and 1 doctors’ room. (Figure 1). All 6 IRs with positive aspergillus culture were being occupied by patients at least 8 days. Among 6 patients, 3 had already been diagnosed with CAPA whereas the other 3 were not diagnosed with CAPA through the observation period. Among 4 patients in isolation rooms without airborne aspergillus contamination, one patient had been diagnosed as CAPA before air sampling. (Table 3). Conclusion Association between CAPA and airborne aspergillus contamination within the negative pressure room could not be demonstrated in this study. Rather than environmental factors, patient factors such as older age, ventilator care, and lymphopenia were found to be associated with CAPA diagnosis. Disclosures All Authors: No reported disclosures.

Maternal-Neonatal Outcomes of Obstetric Deliveries Performed in Negative Pressure Isolation Rooms during the COVID-19 Omicron Variant Pandemic in Taiwan: A Retrospective Cohort Study of a Single Institution.

Objective: To investigate the maternal–neonatal outcomes of obstetric deliveries performed in negative pressure isolated delivery rooms (NPIDRs) during the coronavirus disease 2019 (COVID-19) omicron variant pandemic period in a single tertiary center in northern Taiwan. Methods: Confirmed positive and suspected-positive COVID-19 cases delivered in NPIDRs and COVID-19-negative mothers delivered in conventional delivery rooms (CDRs) in the period of 1 May 2022 to 31 May 2022 during the COVID-19 omicron variant pandemic stage were reviewed. The maternal–neonatal outcomes between the two groups of mothers were analyzed. All deliveries were performed following the obstetric and neonatologic protocols conforming to the epidemic prevention regulations promulgated by the Taiwan Centers for Disease Control (T-CDC). Multiple gestations, deliveries at gestational age below 34 weeks, and major fetal anomalies were excluded from this study. Results: A total of 213 obstetric deliveries were included. Forty-five deliveries were performed in NPIDRs due to a positive COVID-19 polymerase chain reaction (PCR) test (n = 41) or suspected COVID-19 positive status (n = 4). One hundred and sixty-eight deliveries with negative COVID-19 PCR tests were performed in CDRs. There was no statistical difference in maternal characteristics between the two groups of pregnant women. All COVID-19-confirmed cases either presented with mild upper-airway symptoms (78%) or were asymptomatic (22%); none of these cases developed severe acute respiratory syndrome. The total rate of cesarean section was not statistically different between obstetric deliveries in NPIDRs and in CDRs (38.1% vs. 40.0%, p = 0.82, respectively). Regardless of delivery modes, poorer short-term perinatal outcomes were observed in obstetric deliveries in NPIDRs: there were significant higher rates of neonatal respiratory distress (37.8% vs. 10.7%, p < 0.001, respectively), meconium-stained amniotic fluid (22.2% vs. 4.2%, p < 0.001, respectively) and newborn intensive care unit admission (55.6% vs. 8.3%, p < 0.001, respectively) in obstetric deliveries performed in NPIDRs than in CDRs. Maternal surgical outcomes were not significantly different between the two groups of patients. There was no vertical transmission or nosocomial infection observed in COVID-19 confirmed cases in this study period. Conclusions: Our study demonstrates that obstetric deliveries for positive and suspected COVID-19 omicron-variant cases performed in NPIDRs are associated with poorer short-term perinatal outcomes. Reasonable use of personal protective equipment in NPIDRs could effectively prevent nosocomial infection during obstetric deliveries for pregnant women infected with the COVID-19 omicron variant.

HVAC Control Systems for a Negative Air Pressure Isolation Room and Its Performance

The controlled environment room, called an isolation room, has become a must have for medical facilities, due to the spreading of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), to isolate the high risk infected patients. To avoid the transmission of the virus through airborne routes, guidelines were published by the government and the association. A medical facility must comply with this document for high-risk patient treatment. A full-scale N class isolation room was built at Syiah Kuala University to investigate the performance in terms of the controller, temperature, pressure, humidity, and energy consumption. The isolation room was equipped with a proper capacity heating, ventilating, and air conditioning (HVAC) system, which consisted of an air conditioning compressor and a negative pressure generator (NPG), and its installation was ensured to fulfil the guidelines. Since the current NPG was controlled manually, a computer-based control system was designed, implemented, and compared with the manual control. The results showed that the computer-based control outputs better stability of pressure and electric power. For that reason, a computer-based control was chosen in the real case. To investigate the performance of the isolation room, a 24 h experiment was carried out under different parameter setups. The results showed that improvement of the control strategy for temperature and humidity is still necessary. The energy consumption during the activation of the NPG for the recommended negative pressure was slightly different. An additional piece of equipment to absorb the heat from the exhaust air would be promising to improve the energy efficiency.

Failure to Detect SARS-CoV-2 RNA in the Air During Active Labor in Mothers Who Recently Tested Positive.

The risk of potential SARS-CoV-2 transmission by infected mothers during labor and delivery has not been investigated in-depth. This work collected air samples close to (respiratory droplets) and more distant from (aerosol generation) unvaccinated patients who had previously tested positive for SARS-CoV-2 during labor within 5 days of a positive test. All but one of the patients wore masks during the delivery, and delivery was carried out in either birthing or negative pressure isolation rooms. Our work failed to detect SARS-CoV-2 RNA in any air samples for all of the six patients who gave birth vaginally, despite validation of the limit of detection of the samplers. In sum, this brief report provides initial evidence that the risk of airborne transmission of SARS-CoV-2 during labor may be mitigated by the use of masks and high ventilation rates common in many modern U.S. medical facilities; however more work is needed to fully evaluate the risk of SARS-CoV-2 transmission during labor and maternal pushing.

Knowledge, Attitudes, and Beliefs of Pediatric Health Care Workers: Understanding the Response to COVID-19.

IntroductionThis research aims to assess knowledge, attitudes, and beliefs of PHCW regarding COVID-19.MethodData collected using an electronic survey sent to pediatric health care workers.ResultsAge was not likely to influence willingness to care for patients with COVID-19. Males were more likely to be willing to care for patients than female. Nurse practitioners were more likely to be willing to care for patients with COVID-19 than physicians. Availability of proper personal protective equipment, COVID-19 knowledge, and training did not influence willingness to care for COVID-19 patients. Healthcare workers with a higher risk of COVID-19-related sickness, and who received most of their COVID-19 information from social media, were less likely to be willing to care for COVID positive patients. As perception of hospital preparedness increased, reluctance to care for COVID-19 positive patients decreased.DiscussionHospital preparedness and social media exposure play a significant role in willingness to care for patients with COVID-19.

The Effect on COVID-19 Infection Control Practice of Nurses who Work in Working Sites with Negative Pressure Isolation Rooms

Purpose : This study aimed to identify the factors affecting coronavirus disease 2019 (COVID-19) infection control practices of nurses in negative pressure isolation rooms.Methods : The participants were 150 nurses working in three hospitals with negative pressure isolation rooms. Data were collected using structured questionnaires and analyzed using an independent t-test, one-way ANOVA, Scheffé test, Pearson correlation coefficients, and multiple regression analysis using the SPSS/WIN 26.0 program.Results : Factors significantly influencing the subject's COVID-19 infection control practice include Being married (&lt;i&gt;β&lt;/i&gt;=.18, &lt;i&gt;p&lt;/i&gt; =.016), working in a ward with negative pressure isolation rooms (&lt;i&gt;β&lt;/i&gt;=.44, &lt;i&gt;p&lt;/i&gt; &lt;.001), working in an ICU with negative pressure isolation rooms (&lt;i&gt;β&lt;/i&gt;=.27, &lt;i&gt;p&lt;/i&gt; =.010), COVID-19 infection control attitude (&lt;i&gt;β&lt;/i&gt;=.28, &lt;i&gt;p&lt;/i&gt; =.001), anxiety for COVID-19 (&lt;i&gt;β&lt;/i&gt;=.30, &lt;i&gt;p&lt;/i&gt; &lt;.001). The explanatory power of these variables for COVID-19 infection control practice was 24.6% (F=8.67, &lt;i&gt;p&lt;/i&gt; &lt;.001).Conclusion : It is expected that strategies that utilize positive attitudes which believe that COVID-19 disease may be overcome by COVID-19 infection control practice will help improve emerging infectious diseases infection control practice.