Negative Health Conditions Research Articles

Personalized Training Profile

The personalization of health and personal care services has become popular in the development of smart cities. In this sense, it is important to develop physical activities to prevent diseases and physical conditions that affect health. In this paper we define the problem called Personalized Training Profile to identify the initial physical and health conditions of a person and, subsequently, track these conditions based on factors such as age, height, weight, height, body mass, and body fat, among others, to predict possible scenarios during physical training and prevent injuries or negative health conditions.

Adverse Childhood Experiences and Health Conditions and Risk Behaviors Among High School Students - Youth Risk Behavior Survey, United States, 2023.

Adverse childhood experiences (ACEs) are preventable, potentially traumatic events occurring before age 18 years. Data on ACEs among adolescents in the United States have primarily been collected through parent report and have not included important violence-related ACEs, including physical, sexual, and emotional abuse. This report presents the first national prevalence of self-reported ACEs among U.S. high school students aged <18 years, estimates associations between ACEs and 16 health conditions and risk behaviors, and calculates population-attributable fractions of ACEs with these conditions and behaviors using cross-sectional, nationally representative 2023 Youth Risk Behavior Survey data. Exposures were lifetime prevalence of individual (emotional, physical, and sexual abuse; physical neglect; witnessed intimate partner violence; household substance use; household poor mental health; and incarcerated or detained parent or guardian) ACEs and cumulative ACEs count (zero, one, two or three, or four or more). Health conditions and risk behaviors included violence risk factors, substance use, sexual behaviors, weight and weight perceptions, mental health, and suicidal thoughts and behaviors. Bivariate analyses assessed associations between individual and cumulative ACEs and demographics. Adjusted prevalence ratios assessed associations between cumulative ACEs and health conditions and risk behaviors, accounting for demographics. Population-attributable fractions were calculated to determine the potential reduction in health conditions and risk behaviors associated with preventing ACEs. ACEs were common, with approximately three in four students (76.1%) experiencing one or more ACEs and approximately one in five students (18.5%) experiencing four or more ACEs. The most common ACEs were emotional abuse (61.5%), physical abuse (31.8%), and household poor mental health (28.4%). Students who identified as female; American Indian or Alaska Native; multiracial; or gay or lesbian, bisexual, questioning, or who describe their sexual identity in some other way experienced the highest number of ACEs. Population-attributable fractions associated with experiencing ACEs were highest for suicide attempts (89.4%), seriously considering attempting suicide (85.4%), and prescription opioid misuse (84.3%). ACEs are prevalent among students and contribute substantially to numerous health conditions and risk behaviors in adolescence. Policymakers and public health professionals can use these findings to understand the potential public health impact of ACEs prevention to reduce adolescent suicidal behaviors, substance use, sexual risk behaviors, and other negative health conditions and risk behaviors and to understand current effects of ACEs among U.S. high school students.

Reversing Mental Health &amp; Chronic Stress Related Diseases

Most chronic diseases are psychosomatic, arising from persistent maladaptive stress caused by prolonged negative mental health conditions, frequently subconscious, that disrupt physiological functions. Emotions are biochemical manifestations of cognition and thought processes. We transform mental health and chronic illnesses by revising beliefs and cognition while supplying the body with essential cellular nourishment.

Finding Groups in the Portuguese Population Through Lifestyle: A Cross-Sectional Study.

Lifestyle interventions are recognized as essential in the prevention and treatment of noncommunicable diseases, the main causes of multimorbidity. A population-based cross-sectional study was carried out in mainland Portugal. 891 Portuguese patients aged ≥20 years, representative of the population, were personally interviewed. For lifestyle, diet and alcohol consumption, physical activity and sedentarism, use of tobacco and illicit drugs, sleeping habits, screen activities and stress, were studied. The bio-sociodemographic data reported were age, sex, marital status, highest level of education, body mass index and health problems in the last 12 months. This study aimed to apply principal components analysis and clustering to identify distinct groups within the population based on lifestyle. It was possible to identify 3 groups: cardiometabolic, healthy and anxious-depressive. It seems very likely that smoking cessation and other behavioral changes only occur after negative health conditions occur.

Assessing Mental Health Conditions in Women with Gestational Diabetes Compared to Healthy Pregnant Women.

Pregnant women with gestational diabetes mellitus (GDM) experience higher psychological stress levels than healthy pregnant women. The objectives of the current study were to examine (1) the differences in anxiety, depression, stress, and somatization levels between women diagnosed with GDM and healthy pregnant women, and (2) the differences in anxiety, depression, stress, and somatization levels among women with well-controlled blood sugar levels compared to those who are not well controlled. A quantitative cross-sectional study was conducted, involving 103 women who had been pregnant at least once, including 40 women diagnosed with GDM and 63 healthy pregnant women. An online questionnaire was distributed that included three parts: socio-demographic parameters, the DASS-21 questionnaire assessing anxiety, depression, and stress, and the Brief Symptom Inventory (BSI) questionnaire assessing somatization. Differences in the anxiety (t = 14.470, <0.001), depression (t = 8.17, <0.001), stress (t = 16.354, <0.001), and somatization (t = 13.679, <0.001) levels between women diagnosed with GDM and healthy pregnant women were found. Women diagnosed with GDM reported higher levels of anxiety, depression, stress, and somatization compared to those without GDM. Additionally, women with better blood sugar control, as indicated by lower glycated hemoglobin (HbA1c) levels had lower anxiety (t (38) = -2.04, p < 0.05), depression (t(38) = -2.88, p < 0.01), stress (t(38) = -1.88, p < 0.05), and somatization (t(38) = -1.88, p < 0.05) levels compared to women with poorer blood sugar control. Pregnant women diagnosed with GDM report higher levels of negative mental health conditions such as anxiety, depression, stress, and somatization compared to healthy pregnant women.

Impact of Food Insecurity and Community and Federal Food Assistance Program Usage on Experiencing a Negative Health Condition Among Latinx Individuals in the NC High Country

Impact of Food Insecurity and Community and Federal Food Assistance Program Usage on Experiencing a Negative Health Condition Among Latinx Individuals in the NC High Country

Comparison of acute glucose responses following combined arm and leg cycling in non and pre-diabetic males

Prolonged and chronic sedentary behavior contributes to negative metabolic health conditions. Recent research has shown that a single bout of combined arm and leg cycling (CALC) can improve acute glucose metabolism in non-diabetic college aged adults. If a short bout of CALC can improve glucose metabolism in individuals that are non-diabetic then one could hypothesize that a short bout of CALC may improve glucose metabolism in individuals that are pre-diabetic. We hypothesized that short bouts of CALC would result in a greater decrease in the 60-min total (tAUC) area under the curve in pre-diabetic compared to non-diabetic males. PURPOSE: To compare acute glucose responses following a short bout of CALC in non and pre-diabetic males. METHODS: College age males were recruited for this trial. Diabetes status was based upon a fasting blood glucose measurement taken after an overnight 12 hour fast. Participants completed three randomized experimental trials. Two of the experimental trials consisted of a 1-min (1M) or 5-min (5M) bout of CALC at a self-selected pace. The third trial was a non-exercise control (CON) trial. Immediately following both exercise trials and during the CON trial, participants completed a 60-min oral glucose tolerance test. A 2-way (diabetes status vs trial) repeated measures ANOVA was done to determine if there were any significant differences between the two groups and the three trials for the tAUC during the 60-min OGTT. RESULTS: A total of 18 college age males completed this study. Fasting blood glucose was 94.0 ± 3.7 and 108.1 ± 4.6 mg/dl for the non (n=8, 21.4 ± 2.4 yrs) and pre-diabetics (n = 10, 22.6 ± 3.9 yrs) participants respectively. There was a significant interaction between trials and diabetes status (p = 0.04) for tAUC. Follow-up analysis showed that within the pre-diabetic group, tAUC was significantly lower in the 5-min trial compared to the CON trial (113.7 ± 22.5 mg/dl, p &gt; 0.001). Within the pre-diabetic group, the tAUC for the 1M trial was not significantly different from the CON or 5M trials. Within the non-diabetic group, there were no significant differences in tAUC between the three trials. CONCLUSIONS: The results of this study indicate that a 5M bout of CALC done at a self-selected pace may have the ability to acutely improve glucose metabolism in college age pre-diabetic males when compared to non-diabetic males. Supported by a SIUE Graduate School Research Grant for Graduate Students, the School of Education, Health, and Human Behavior Dean's Grant, and the Undergraduate Research and Creative Activities Program. This is the full abstract presented at the American Physiology Summit 2024 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.

Is Pollution the Primary Driver of Infectious Syndemics?

Syndemics, the adverse interaction of two or more coterminous diseases or other negative health conditions, have probably existed since human settlement, plant and animal domestication, urbanization, and the growth of social inequality beginning about 10-12,000 years ago. These dramatic changes in human social evolution significantly increased opportunities for the spread of zoonotic infectious diseases in denser human communities with increased sanitation challenges. In light of a growing body of research that indicates that anthropogenic air pollution causes numerous threats to health and is taking a far greater toll on human life and wellbeing than had been reported, this paper proposes the possibility that air pollution is now the primary driver of infectious disease syndemics. In support of this assertion, this paper reviews the growth and health impacts of air pollution, the relationship of air pollution to the development and spread of infectious diseases, and reported cases of air pollution-driven infectious disease syndemics, and presents public health recommendations for leveraging the biosocial insight of syndemic theory in responding to infectious disease.

Concentrations and probable health risks of potentially toxic metals (Pb, Cd and Cr) in some Nigerian lipstick products

BackgroundLipstick is one of the widely used cosmetic items that are produced from both natural and processed materials and they are one of the sources of metals and metalloids released among the users. This study measured concentrations of Pb, Cd and Cr in some brands of Nigerian lipstick products and assessed their probable health risks to the users. MethodsA total of twenty (L1 - L20) brands of lipstick products were purchased from the central cosmetic stores and the samples were prepared, digested and concentrations of Pb, Cd and Cr were determined using Atomic Absorption Spectrometry (AAS). The probable health risk was assessed via average daily dose (ADD) by ingestion route, hazard quotient (HQ), hazard index (HI), cancer risks (CR), and relative intake index (RII). ResultsThe ranges of concentrations of Pb, Cd and Cr were 5.6 - 25.1, 2.5 - 21.5 and 5.0 - 61.7 μg g−1, respectively. The ranges of ADD values of Pb, Cr and Cd were 1.2 × 10−3 - 5.7 × 10−3; 1.3 × 10−3 - 5.7 × 10−3 and 5.1 × 10−3 - 1.4 × 10−3 µg day−1, respectively. Among the samples Cr had HQ values 1.3 to 9.6. The HQ values of Cd for L2, L6, L12 and L14 ranges between 1.1 and 1.5. Then HQ values of Pb for L1 -L20 were 1.0 - 4.1. The HI values of Pb, Cr and Cd in each lipstick brands range from 2.8 to 12.5, indicating a non-carcinogenic health risk. The CR values for Cr and Cd are from 6.6 × 10−4 to 6.9 × 10−4 and from 2.0 × 10−2 to 2.5 × 10−2, respectively and they were within the acceptable limit value of 1.0 × 10−4. The RII of Pb, Cd and Cr were 4.50 - 20.1, 2.0 – 19.2 and 1.9 – 23.0 %, respectively. ConclusionAll the health indices indicated non-carcinogenic health risks. The continuous exposure and unintentional ingestion of such lipstick products can pose high risks to the users due to bioaccumulation of Pb, Cd and Cr which may lead to negative health conditions.

HEALTH CARE SETTINGS: A MISSED OPPORTUNITY TO ADDRESS HEARING LOSS

Abstract Background Identifying hearing loss (HL) within the healthcare system is essential to mitigate its risk for associated negative psychosocial and health conditions, including isolation and depression yet is rarely assessed. This qualitative study sought to gain in-depth understandings of how HL affects communication regarding care preferences within the older adult-partner dyad in the context of chronic illness. Its premise was that older adults with HL may not be able to participate effectively in care discussions and are at risk of not receiving patient centered care. Method: Planned as in-person, pandemic restrictions mandated transition to zoom. 15 older adults (≥60) with HL and 13 partners participated. Results One key story line evolving from the data is “Compulsory Self-Advocacy”. Almost uniformly, participants reported that healthcare practitioners “Never Asked” about HL. During one-on-one communication, HL wasn’t necessarily brought to the surface and often went unnoted because participants didn’t see it as pertinent to issues discussed. Still, they were unsure the practitioner was aware of their HL. Rather, they asked that information be repeated or noted they had trouble hearing or understanding when they realized problems. Reporting their HL didn’t generally result in on-going consideration of their specific communication needs. They had to self-advocate to obtain accurate information or bring their partner to appointments to help. Some commented on the value of policies mandating access to notes or written reports. Conclusions Healthcare settings provide unique opportunities to identify HL and initiate interventions that may mitigate its negative effects, including social isolation and loneliness.

HIGHER STRESS AMONG ETHNIC MINORITY ADULT-CHILD CAREGIVERS COMPARED TO SPOUSAL CAREGIVERS IN DEMENTIA CARE

Abstract Ethnic minority family caregivers of persons with dementia (PWD) suffer from negative health conditions resulting from continuous care responsibility for PWD. While adult-child caregivers have additional family care and job responsibilities, cultural and linguistic needs in ethnic minority families further compound caregiving challenges. Little research examines ethnic minority caregivers’ health statuses. This study aimed to understand the emotional health status and dementia care experiences of minority caregivers, between spouses and adult-children. The study collected cross-sectional survey data on perceived stress and utilizations of caregiving resources: Alzheimer’s agencies, state-funded in-home supportive service, adult-day service, support groups, and caregiving education. Recruitment focused on diverse communities with special emphasis on minority caregivers who speak Spanish, Vietnamese, or Korean in California. Seventy-six caregivers participated in surveys in their respective language; 42% Korean, 38% Vietnamese, 20% Spanish; 49% spouses/partners vs 51% adult-children/grandchildren; 78% females; 55% PWD with Medicaid; Mean English Proficiency (EP) of 3/5(1.3). Sixty-four percent of adult-child caregivers were employed (full-time or part-time) compared to 5% of spousal caregivers (P&amp;lt;.05). Adult-child caregivers showed higher stress compared to spousal caregivers (P&amp;lt;.05) despite no differences in PWD’s activities of daily living (ADL) scores and instrumental ADL scores. Although EP of adult-child caregivers was higher than spousal caregivers (P&amp;lt;.05), both caregivers underutilized care resources and showed little awareness of Alzheimer’s agencies. Findings demonstrated higher caregiving stress of adult-child caregivers compared to spousal caregivers of PWD among minority groups. Tailored interventions with appropriate language and cultural aspects should consider the caregiver’s relationship to the PWD.

Redefining “LGBTQ+ InterCulture” in Academia

Members of the LGBTQ+ community often face discrimination, harassment, and exclusion in academic settings, which can negatively impact their academic and personal success. Studies have shown that LGBTQ+ students are more likely to experience negative mental health conditions, drop out of school, and struggle to find employment after graduation. Cultural humility fosters diversity, equity, and inclusion, which is critical to ensuring an equitable educational experience for all students, particularly those from marginalized communities. Intercultural understanding is essential to develop cultural humility so that attitudes reflect empathy and tolerance of differences, including sexual or gender orientation variances or ambiguity. Understanding how the power embedded in cultural climate marginalizes some while privileging others is vital to achieving equity.

Violent Victimization During Childhood in the United States: Associations With Revictimization and Health.

Childhood violence victimization is a serious adverse childhood experience with lasting health impacts. This study examined the prevalence and characteristics of five forms of childhood violence victimization and their association with revictimization and negative health conditions among adults. Data are from the 2010-2012 National Intimate Partner and Sexual Violence Survey. Age at first victimization and perpetrator sex were assessed; adjusted odds ratios assessed associations with revictimization and health. Ages 14-17 were the most common age at first victimization for most violence types; almost half of male (46.7%) and a quarter of female (27.0%) rape victims reported first victimization before age 10. Most victimization was associated with revictimization and negative health, controlling for adult victimization. Primary prevention of childhood violence may reduce later health risks.

Reasons for parental hesitancy or refusal of childhood vaccination in Türkiye.

Although vaccines play a critical role in the control of infectious diseases and disease outbreaks, vaccination rates have been declining in recent years because of vaccine hesitancy or refusal. We aimed to determine the rates and reasons for parental hesitancy or refusal of vaccination for their children in Türkiye. A total of 1100 participants selected from 26 regions of Türkiye were involved in this cross-sectional study conducted between July 2020 and April 2021. Using a questionnaire, we collected data on the sociodemographic characteristics of parents, the status of vaccine hesitancy or refusal for their children, and reasons for the hesitancy or refusal. Using Excel and SPSS version 22.0, we analysed the data with chi-square test, Fisher's exact test and binomial logistic regression. Only 9.4% of the participants were male and 29.5% were aged 33-37 years. Just over 11% said they were worried about childhood vaccination, mainly because of the chemicals used in manufacturing the vaccines. The level of concern was greater among those who got information about vaccines from the internet, family members, friends, TV, radio, and newspapers. Those who used complementary health services were considerably more hesitant about vaccination than those who used mainstream services. Parents in Türkiye have several reasons for hesitating or refusing to vaccinate their children, key among which are concerns about the chemical composition of the vaccines and their ability to trigger negative health conditions such as autism. This study used a large sample size across Türkiye, although there were differences by region, the findings would be useful in designing interventions to counter vaccine hesitancy or refusal in the country.

Feeding Homemade Sugar Sweetened Beverages in Addition to Breastfeeding: Survey Results from Caregivers of Infants and Young Children in Peri-Urban Lima, Peru.

Consumption of sugar sweetened beverages (SSB) is associated with childhood obesity and other negative health conditions. Feeding SSB to infants and young children (IYC) under 2years may displace consumption of breastmilk and nutrient rich foods critical for optimal growth and development. The World Health Organization (WHO) recommends avoiding added sugar (e.g. SSB) for IYC under 2years. We sought to describe the variety of homemade and commercial SSB as well as breastmilk and beverages without added sugar fed to IYC aged 4-23months living in a low-income, populous peri-urban area of Lima, Peru. A cross-sectional survey was conducted with 181 households with IYC aged 4-23months. A list of common local homemade and commercial beverages was used to investigate what caregivers had fed to the child in the past 24h. A total of 93.9% of caregivers reported feeding at least one beverage to their child other than breastmilk in the past 24h. This included a variety of homemade SSB (73.5%), commercial SSB (18.2%) and homemade beverages without added sugar (70.2%). A high percentage (83.4%) of children were also breastfed. Our findings suggest that interventions toaddress feeding homemade SSB to IYC within householdsare needed to support WHO recommendations and complement current commercial SSB policy regulations in Peru.

TikTok use and psychosocial factors among adolescents: Comparisons of non-users, moderate users, and addictive users

Short-video applications like TikTok are increasingly popular. This study examines the association between short-video application use (SVU) and psychosocial factors in 1,346 adolescents (Mage = 14.97, 51.8% female). 199 non-users and 1147 users (686 moderate users, 461 addictive users) were identified. Results revealed a high prevalence of addictive SVU in the sample. Addictive users exhibited worse mental health conditions than non-users and moderate users, including higher levels of depression, anxiety, stress, loneliness, social anxiety, attention problems, and lower life satisfaction and sleep quality. Addictive users also faced higher academic stress, poorer academic performance, more bullying victimization, worse parental relationships, more negative parenting styles, and lower parental education levels. Moderate users had different family environments than non-users, but no differences in mental health or school performance. Together, these findings suggest that addictive users experience a more disadvantageous situation across mental health, family, and school conditions, while non-users have advantageous family environments. Moderate SVU may not be associated with negative mental health condition or poor school performance. Moderate and addictive SVU should be considered distinct phenomena. Given the psychiatric symptoms present in addictive users of TikTok and similar apps, targeted interventions and treatments are urgently needed.

Are Women Always Right? Comparing HPV Knowledge Between Men and Women

Background Human papillomavirus (HPV) infection is the most common sexually transmitted infection in the world contributing to negative health conditions in both genders. However, when comparing knowledge about HPV, women show having more knowledge about HPV. Research has shown more women were aware of the virus than men. Women also initiate HPV vaccination more than men with more knowledge about HPV associated with being vaccinated. Such findings suggest that gender comparisons in HPV research should be considered when discussing HPV prevention. Hypothesis Young adult women have more knowledge about HPV than young adult men. Methods A total of 1302 young adults (men: n=393; women: n=909) were surveyed on their level of knowledge concerning HPV. Each answered various knowledge-based questions related to HPV. Logistic regression was performed to conclude whether women have more knowledge about HPV than men. Results All our HPV knowledge measures were statistically significant (p &lt;.05) in our logistic regression models. These 9 HPV knowledge questions were: general HPV knowledge (p &lt; .001), knowledge of HPV commonality within women (p &lt; .001), knowledge of HPV commonality within men (p &lt; .001), HPV’s risk of genital herpes (p &lt; .001), HPV’s risk of genital warts (p = .001), HPV’s risk of oral cancer (p &lt; .001) HPV’s risk of anal cancer (p = .005) HPV’s risk of cervical cancer (p &lt; .001), and knowledge of HPV being sexually transmitted (p = .001). Conclusion Our data show that women are more likely to be knowledgeable about HPV than men. Our sample contained more women than men. Research including equal amounts of men and women could further investigate this relationship.

A qualitative study of university students' perspectives of hope during the COVID-19 pandemic.

Students in higher education commonly experience mental health problems. There is an ongoing need to explore potential intervention targets to focus on mental health promotion among students. Hopefulness may alleviate or be protective against various negative mental health conditions such as depression, anxiety, suicide, and trauma-related disorders. To explore postsecondary students' meanings and experiences of hope during the COVID-19 pandemic and identify factors affecting hopefulness during crises. Purposive sampling was used to recruit participants for online semi-structured interviews in a university located in Southwestern Ontario, Canada. Data were analyzed using thematic analysis. In total, 12 participants were interviewed, and 4 themes were generated: (1) hope is a complex concept with an associated set of behaviors, (2) cognitive framing of hope as a means of student resilience, (3) COVID-19 as an antagonist which amplifies preexisting student concerns and issues, and (4) the social and physical environments serve as barriers and enablers to hope and well-being. Hope was perceived as a positive mental trait, external events and the environment were reported to impact hope, and those who were generally more hopeful adjusted better mentally when unexpected circumstances arose. Findings shed light on the interconnectedness and complex nature of hope, its sources, and enablers. Novel findings include the ways in which hope was affected during the COVID-19 pandemic. Recommendations for individual- and community-based interventions include targeting enablers to hopefulness by promoting social support systems, offering virtual extracurricular activities, and delivering alternative approaches to teaching and learning.

Positivity and Post-Traumatic Stress Disorder (PTSD) in COVID-19 Survivors: Mediating Role of Rumination and Fear of COVID-19.

COVID-19 pandemic, which still continues to affect the whole world, has led to an increase in PTSD symptoms in societies, especially individuals who have been diagnosed with the disease and recovered are at significant risk for PTSD have been reported. Although it has been observed that PTSD symptoms of individuals who were infected in the past epidemics such as SARS and Ebola continued for a long time even after the epidemic, it is noteworthy that the studies conducted during the COVID-19 process do not focus enough on people who survived the COVID-19 disease. The purpose of this study is to determine the direct and indirect impact of positivity on PTSD symptoms of individuals who have recovered from COVID-19 and the role of rumination and fear of COVID-19 as potential mediators in this effect. In the study, the Impact of Event Scale-Revised, Ruminative Response Scale, Positivity Scale, and Fear of COVID-19 Scale were applied to 551 Turkish participants, who survived the COVID-19 disease. SEM-based mediation analysis was used to test hypothesized relationships. Mediating roles of fear of COVID-19 and rumination between positivity and PTSD were tested. Results indicated that rumination and fear of COVID-19 had a full mediating role in the relationship between positivity and PTSD. These findings pointed out that positivity might be an indirect protective disposition against COVID-19-related PTSD and might reduce risk factors associated with PTSD among COVID-19 survivors. Mental health practices for COVID-19 patients should aim to increase positive thinking, since they have ruminative thoughts about transmission of the virus and hospitalization process and these thoughts may lead to negative mental health conditions. In this sense, positive psychology-focused implementations can be organized for COVID-19 patients and survivors.

Total Pain and Illness Acceptance in Pelvic Cancer Patients: Exploring Self-Efficacy and Stress in a Moderated Mediation Model.

Cancer patients experience pain not only in its physical dimension, but also in a broader context that includes psychological, social, and spiritual aspects due to a higher level of anxiety and stress. The present prospective, longitudinal study examined the relationship between total pain and illness acceptance among pelvic cancer patients, taking into consideration the moderated mediation effects of self-efficacy and stress. The study involved a sample of pelvic cancer patients receiving radiotherapy treatment. Assessments were completed at T1 (before radiotherapy), T2 (after 3–4 weeks), and T3 (after radiotherapy) to assess the psychosocial dynamics of illness acceptance (N = 267). The more physical, psychological, social, and spiritual pain symptoms the patients experienced, the less they accepted negative health conditions and the effects of their illness. Stress moderated the indirect effect between total pain dimensions and illness acceptance through self-efficacy, but it did not moderate the relationship between total pain and illness acceptance. The relationships between total pain dimensions and illness acceptance thus depend on both the mediating effect of self-efficacy and the moderating effect of stress. This highlights the need to control one’s motivation and behavior and manage emotional strain or tension.