TOPIC: Cardiothoracic Surgery TYPE: Medical Student/Resident Case Reports INTRODUCTION: Vanishing lung syndrome (VLS) is also known as giant bullous emphysema (GBE) and is a subset of emphysema in which bullae occupy more than one-third of the affected hemithorax. Often this causes mass effect on adjacent structures including normal lung parenchyma and the mediastinum. Video-assisted thoracic surgery (VATS) has been shown to safely and effectively treat GBE leading to improved symptoms and lung function1. Traditionally, chest radiography and computerized tomography (CT) scans have been used for surgical planning and patient education prior to lung volume reduction surgery. Virtual reality (VR) has emerged as a potentially useful adjunct for preoperative patient education2 and it was utilized in this case of VLS. CASE PRESENTATION: A 56-year-old African-American male was referred to our thoracic surgery clinic for progressive dyspnea. He was unable to walk one city block without stopping. On examination, he could not complete a sentence without stopping. Breath sounds were absent on the left and diminished on the right. Chest radiography (fig. 1) and CT scan (fig. 2) revealed asymmetrical bullous disease significantly worse on the left with mass effect on the remaining normal lung parenchyma, creating the vanishing lung phenomenon. Pulmonary function tests were significant for FEV1 0.88L (23% predicted), FEF25-75% 0.43 L/sec (12% predicted), and RV 205%. DICOMs from the patient's CT were used to create the 360°VR rendering. The immersive 360°VR experience utilizes the Oculus Rift headset to engage the patient who then becomes an avatar navigating through his or her own chest. At thoracoscopy, we encountered extensive air trapping requiring decompression of the giant bullae prior to resection. On extubation, the patient immediately desaturated to SpO2 of 22% requiring immediate needle decompression and placement of a 28F right-sided chest tube. Post-operatively, the patient reported improvement in his dyspnea. Following treatment for pneumonia, he was discharged to home with supplemental oxygen. In clinic 3 weeks postoperatively, his dyspnea was substantially improved, and he was able to walk and bicycle more regularly. He used supplemental oxygen as needed at night. DISCUSSION: Here we demonstrate the use of 360°VR as an imaging adjunct to assist in patient education and preoperative planning in select cases. CONCLUSIONS: Our prior research has demonstrated that compared to standard consultation, 360°VR consultation provides significantly higher levels of understanding and comfort with the proposed treatment option3. The use of 360°VR consultation in this case of VLS reaffirms both the value and ease of utilizing virtual reality as a novel imaging adjunct in the preoperative setting. REFERENCE #1: Geddes D, Cavies, M, Koyama, H, Hansell D. Effect of lung-volume-reduction surgery in patients with severe emphysema. NEJM. 2000; 343:239-245. doi: 10.1056/NEJM200007273430402. REFERENCE #2: Pandrangi VC, Gaston B, Appelbaum NP, et al. The application of virtual reality in patient education. Annals of Vascular Surgery. 2019; 59:184-189. doi: 10.1016/j.avsg.2019.01.015. REFERENCE #3: Mortman KD, Mortman R, Sadur A. Three hundred and sixty-degree virtual reality consultation for the thoracic surgery patient. J Am Coll Surg 2019;229(4):e211. doi: https://doi.org/10.1016/j.jamcollsurg.2019.08.1439 DISCLOSURES: No relevant relationships by Marie-Genevieve Flood, source=Web Response Consultant relationship with Ethicon Please note: $5001 - $20000 by Keith Mortman, source=Web Response, value=Consulting fee Consultant relationship with Medtronic Please note: $5001 - $20000 by Keith Mortman, source=Web Response, value=Consulting fee Speaker/Speaker's Bureau relationship with BD Please note: $5001 - $20000 by Keith Mortman, source=Web Response, value=Honoraria Employee relationship with Surgical Theater Please note: 2019-2021 Added 03/26/2021 by Aneil Srivastava, source=Web Response, value=Salary No relevant relationships by Mira Tanenbaum, source=Web Response