Needle Eye Research Articles

Identification and genetic analysis of a pervasive 'needle-eye' sperm phenotype in Drosophila sterile hybrid males.

Interspecies hybrid sterility has been extensively studied, especially in the genus Drosophila. Hybrid sterility is more often found in the heterogametic (XY or ZW) sex, a trend called Haldane's rule. Although this phenomenon is pervasive, identification of a common genetic mechanism remains elusive, with modest support found for a range of potential theories. Here, we identify a single precise morphological phenotype, which we call 'needle-eye sperm', that is associated with hybrid sterility in three separate species pairs that span the Drosophila genus. The nature of the phenotype indicates a common point of meiotic failure in sterile hybrid males. We used 10 generations of backcross selection paired with whole-genome pooled sequencing to genetically map the regions underlying the needle-eye (NE) sperm phenotype. Surprisingly, the sterility phenotype was present in ~50% of males even after 10 generations of backcrossing, and only a single region of the X chromosome was associated with sterility in one direction of backcross. Owing to the common phenotype among sterile male hybrids, and the strong effect of individual loci, further exploration of these findings may identify a universal mechanism for the evolution of hybrid sterility.

Unstitching the Past: An Experimental and Microwear Investigation of Dorset (Paleo-Inuit) Needles from the Foxe Basin Region

For Paleo-Inuit cultures, needles are arguably one of the most important artefact types, as they were used to create warm, waterproof clothing that is essential for survival in Arctic environments. This, in combination with the prevalence of needles within archaeological collections, has prompted many researchers to the topic of Paleo-Inuit needles. However, the majority of their studies have approached the material using traditional, typological methodology. A pilot study conducted by Siebrecht et al. (2021) demonstrated that, while needles from several Dorset Paleo-Inuit culture (c. 800 – 1300 AD) sites in the Foxe Basin region were previously considered as typologically identical, microwear analysis highlighted variation in how they would have been made and used over time and across sites. The pilot study also noted variation, across sites, in certain typological attributes, such as needle eye shape, distal end shape, and cross-section shape. The present study aims to expand on these discoveries by considering possible reasons for variability in the attribute of needle cross-section shape. Methodologically, we use microwear analysis, experimental archaeology, and ethnographic collaboration. With this approach, we were able to explore Dorset needle making and sewing practices in more detail than has been possible in prvevious, purely typology-focused studies. Our results showed no observable pattern between cross-section shape and the material being sewn but may reveal links between needle size and the material being sewn, a correlation in different polish types and the duration of needle use, as well as insights into the possible sewing techniques used by Dorset groups. Our study thus offers a fresh perspective on this topic and points to new directions for this area of Arctic archaeological research.

Clinical Observation on the Combination of Ear Tip Bleeding and Babao Eye Ointment Ion Introduction in the Treatment of Needle Eye Heat Toxin Obstruction Syndrome

Clinical Observation on the Combination of Ear Tip Bleeding and Babao Eye Ointment Ion Introduction in the Treatment of Needle Eye Heat Toxin Obstruction Syndrome

A steerable introducer-assisted wire-loop snare technique: A bailout for unsuccessful lead extraction by a Needle's Eye Snare.

The Needle's Eye Snare (Cook Medical) is an effective tool for extracting leads via a femoral vein. However, it sometimes fails to grasp the lead. We describe an alternative method of successfully grasping a lead by creating a wire-loop around the lead with the help of a steerable introducer.

Macro-microscopic Atlas on Heartwood of Pterocarpus santalinus L.f. (Red sandalwood)

Background: Pterocarpus santalinus L.f. (Fam. Leguminosae) is a medium sized, deciduous tree distributed in South India mainly in Andhra Pradesh, Karnataka and Tamil Nadu. The heartwood is highly prized and medicinally useful. The heartwood is used in Indian system of medicine for leucorrhoea, piles, syphilis, vomiting, fever, thirst, purifying blood and in wound healing. Pterocarpus santalinus is one of the ingredients in many Siddha and Ayurvedic formulations namely Cintil Ney, Senchandana Manapagu, Candana Bala, Laksadi Taila and Candanadi lauha. Objective: The present study brings out macro-microscopic atlas on heartwood of medicinal plant Pterocarpus santalinus L.f. Materials and Methods: Sections and powder were observed and photographed under different magnifications with the help of Olympus BX51 Microscopic unit fitted with Olympus Camera. Results: Macroscopically colour, odour and taste; microscopically tyloses, needle eye end fibres, forked fibres with pegged and sharp end, pitted and border pitted vessels, uni-seriate medullary rays, Reddish brownish content, oil globules, simple starch grains, crystal fibres and prismatic crystals of calcium oxalate are the unique diagnostic characters reported. Conclusion: The finding of the present study is believed to be helpful in identifying the genuineness of the heartwood in crude raw drug and also in standardization of herbal formulation containing red sandalwood as ingredient.

Atrial septal perforation with Needle's Eye Snare during transvenous lead extraction.

Although the Needle's Eye Snare (Cook Medical) has been considered useful for lead extraction, serious complications can occur. We presented a case of atrial septal perforation associated with the Needle's Eye Snare. Our case highlights the importance of not persisting with the Needle's Eye Snare to prevent atrial damage.

Introduction

Since its inception in 2018, the aim of the “Creative Encounters” section of Migration and Society has been to off er alternative ways of engaging with “voice” or, more pertinently, as I have argued elsewhere, “to embroider the voice with its own needle” (Qasmiyeh 2019). This dialectic is proposed to problematize the notion of the voice as it is often perceived and mobilized: a medium offered to those in need of (their) voices rather than as a prior state of being that is initiated by and therefore intrinsically belongs to the individual herself. In this vein, “to embroider the voice with its own needle” is to see the voice within its owner, as a given and not to be given, through tracing the thread as it touches the needle eye to go through it and in so doing ushering in the embroidering that will come. Indeed, embroidering the voice is writing the intimate, the lived, and the leftovers in life into newer times as imagined by the writer herself; it is writing without a helping hand from anyone but rather through continuously returning to the embroidered (and what is being embroidered) and its tools, notwithstanding how incomplete and fragmentary they are.

Surgery watch out the needle eye

Surgery watch out the needle eye

Transfemoral extraction of pacemaker and implantable cardioverter defibrillator leads using Needle’s Eye Snare: a single-center experience of more than 900 leads

The femoral approach with the Needle's Eye Snare (NES) is often used for bailout after failure of the superior approach for transvenous lead extraction (TLE). The safety and efficacy of the NES as a first-line tool for TLE remain unclear. The medical records of patients who underwent TLE via the femoral approach utilizing the NES from May 2014 to June 2019 in Peking University People's Hospital were retrospectively reviewed. Nine hundred and eighty-five leads were extracted in 492 patients (369 men; mean age 72.8 ± 29.0years). The median (range) number of leads extracted per patient was 2 (1-6). The mean indwelling time of all extracted leads was 112.6 ± 52.0months. The complete procedure success rate, clinical success rate, and failure rate were 94.1% (463/492), 97.8% (481/492), and 1.1% (11/492), respectively. Major complications including death occurred in nine patients (1.9%), of whom eight developed cardiac tamponade. Among these eight patients, emergency pericardiocentesis followed by rescue surgical repair if necessary was successful in 6 (75.0%) and failed in 2 (25.0%). No significant differences were found in the clinical success rate or major complications rate between patients with pacemakers and implantable cardioverter defibrillators, or between patients with infected and uninfected leads. A femoral approach with the NES is safe and effective for TLE of both pacing and defibrillator leads and could be considered a first-line approach. Cardiac tamponade was the most frequent cardiovascular complication. A strategy of emergency pericardiocentesis followed by a rescue surgical approach seems to be reasonable technique to treat a cardiac tamponade.

The Wives of Frederick Douglass: Sewing a Sailor Outfit for Frederick, and: Call and Response: The Second Wife, and: Throwing Like a Girl

The Wives of Frederick Douglass: Sewing a Sailor Outfit for Frederick, and: Call and Response: The Second Wife*, and: Throwing Like a Girl Marjorie Maddox (bio) The Wives of Frederick Douglass: Sewing a Sailor Outfit for Frederick Anna Murray, first wife of Frederick Douglass, 1813-1882 A free woman, her knuckles raw,she scrubs clothes and floors,sells her bed, collects her few bills for tickets,and stitches her love a sailor-shirt disguiseas red as a soaring cardinal. Sharp needles prick both skin and cloth, pull together two sides of fabric, cover the person traveling. In her dreams, she hears the click-clackof his escape, tracks leading him awayto the unknown and only so-so-brotherly Philadelphia. But first,the conductor's hand, waiting for papers. Runaway, runaway thread, follow the ins-and-outs to safety, hold to his chest this trail of her hands. A borrowed certificate. A nod.Then the engine chugs relief,exhales all the smoky lettershe's learned/he's taught on slateas black as engines, as faces. Her steel needle punctures what protects him, this disguise, this railroad route to freedom. Later she will join him, marry, moveto Massachusetts, birth five babies, moveto Rochester, recreate—from the shelterof her home, from the warmth of her wide-openwashing/sewing arms—that human train. This motion the beginning: measuring her love, planning the pattern, holding up to the light the needle's eye. Before his days of train-after-train, ship-after-ship,talk-after-talk; before her loneliness, death; beforehis depression, a second marriage that rockedsociety; before all this: just a needle, her needle,and her red thread of hope. [End Page 391] "If there is no struggle," her love said, "there is no progress." Here it is. Cut the cloth. Begin. Yes, Frederick, begin—with your tarpaulin hat,your black scarf, and your red sailor shirtstitched in fear, in joy. What will beis rounding the curve. Listen. Can you hearbeneath the train's roar her fingers stitching? Buy the thread, Anna. Buy the needle. Board the train, Frederick. Step up. Call and Response: The Second Wife* Helen Pitts, 1838-1903 Twenty years younger Lovecame to me and white, and Iand she was not afraid to stand upto marry the man against family,against scandal because of his color smoothcedar The mind does not take its complexionjust one year from the skin after the other's passing and Frederick This proveslifted out of his sorrow I am impartialresponded My first wife deep sorrowwas the color of buckeyes of my motherand the second, this suffragette, thisabolitionist, this partner, the colorof wind-blown wheat of my father and now, his voice weary, I have very littlesympathy but never averting his eyeswith the curiosity of the worldI love, yes, I loveabout my domestic relationswhom I love. [End Page 392] Throwing Like a Girl Seventy-miles Mo'Ne style,fastball, curveball, flashing into-the-futureball, every which way butlosing. Batter's up, so we chant "Mo'ne! Mo'ne!"awake, sleeping, warming upfor the life worth stealingin this home run of a serieswe call "team," we call "You go, Girl," braided phenom with an armthat hurls hope way past today'swhirl of photo ops and change-ups, all the way to a close upof two T-ball boys playing the part,debating, voices escalating "I'm Mo'ne." "No! I'm Mo'ne!" and a summer of daughtersleaning into the pitch that blasts the phrase "throwing like a girl" into the All-Star compliment that it can be, that it is when lean machine Mo'netakes the mound,smiles as wide as a long drive,then delivers the dreamwe braided girls of baseball, basketball, soccer, business, science, writingstill need in whatever and every season. [End Page 393] Marjorie Maddox Winner of America Magazine's 2019 Foley Poetry Prize, Lock Haven University English professor Marjorie Maddox is the great-grandniece of baseball legend Branch Rickey. She is the...

Discussion on dealing skills of complex soft tissue problems in osteomyelitis treated by Ilizarov technique

To discuss skills for the treatment of complex soft tissue problems in osteomyelitis using Ilizarov techniques. The clinical data of 31 patients with complex soft tissue problems during the treatment of osteomyelitis with Ilizarov technique between January 2015 and June 2017 were retrospectively analyzed. There were 23 males and 8 females, with an age of 14-67 years (mean, 37.8 years). All the patients were post-traumatic chronic osteomyelitis, the disease duration was 12 days to 16 months (mean, 6.3 months). They went through 2-8 times surgeries (mean, 3.8 times). There were 29 cases of soft tissue insertion after bone grafting; 1 case of strephopodia and calcaneal osteomyelitis with plantar skin infection defect; 1 case of the open tibial fracture postoperative infection, the skin defect of infection was more than that of bone defect. The soft tissue defect area was 4.5 cm×4.0 cm to 16.5 cm×8.5 cm. Soft tissue depression and insertion was corrected by subcutaneous insertion of Kirschner wire after slow elastic retraction. Soft tissue defects were gradually resolved through slow traction. All patients were followed up 6-24 months (mean, 11.5 months). All wounds healed by first intention, and skin graft and flap repair were not performed in the two stage. One case of strephopodia and calcaneal osteomyelitis with plantar skin infection defect was treated with slow skin traction, no secondary suture was performed; no skin ulceration was found after walking for 3 months, and the feeling was slightly lower than normal. One case of soft tissue transverse traction wound completely covered, with no bone exposure and no obvious pigmentation of local soft tissue, the feeling was slightly lower than normal, the skin elasticity was worse than normal, and the color, temperature had no obvious abnormalities. There was no severe needle eye reactions in 29 patients with skin depressions corrected by Kirschner wire. Six cases of Kirschner wire showed elastic retraction and lacerate skin; 1 case of plantar skin traction had 2 times of exudation of the needle eye and local skin reddish phenomenon; the symptoms relieved when the traction needle was changed once, the traction was stopped for 1 week, the dressing was changed and antibiotics were used once. One patient with transverse traction had 3 times of pin-eye infection, and the treatment was completed after adjusting the traction device and symptomatic treatment. For most of the complex soft tissue problems in osteomyelitis, early and effective intervention with Ilizarov technique can be easily, economically, and effectively solved, which provides a new way for clinical treatment.

“Spaghetti twisting” technique: a novel method of catching pacemaker leads using a needle's eye snare

Key Clinical MessageThe needle's eye snare has become an indispensable tool in contemporary pacemaker lead extraction techniques. Here, we present a modified method of using the needle's eye snare, named “spaghetti twisting” technique, to catch and secure pacemaker leads, which would help operators catch and secure leads much easily.

Investigation and present condition analysis on the venous transfusion recognition of inpatients

Objective To investigate the related knowledge recognition to the venous transfusion of inpatients in the area of Chongqing by releasing the recognition questionnaire form of venous transfusion. Methods The venous transfusion treatment team of our hospital designed the questionnaire form of the venous transfusion recognition condition of inpatients according to the related guide.Delphi expert consultation method was used to revise and consummate the questionnaire form.In addition, picking method was used to release 2 000 questionnaire forms to 21 different levels of hospital in Chongqing, and 1 840 copies were returned. Results The total score of the related knowledge of 20 items to the venous transfusion of patients was (53.65±20.45). The items that had low score were the time of needle eye with water and hot compress after the withdrawal of needles, adverse drug reaction and correct pressing method after withdrawal of needles, selection principle of venous transfusion tool and precaution of phlebitis.The comparison of groups: ①With the grouping comparison at different ages, the comparison difference of the related knowledge acquisition of patients had statistical significance(P 0.05). The difference had statistical significance for the comparison in the groups of 18~40 years old, 61~80 years old, 41~60 years old and 61~80 years old(P 0.05). Conclusions The general related knowledge acquisition of inpatients to venous transfusion treatment is poor in the region of Chongqing.The related knowledge acquisition of patients who are more than 60 years old, education background is low, patients in low-class hospital and have transfusion for the first time is worse, indicating that nursing personnel should formulate normalized health education scheme aimed at the related knowledge involved in venous transfusion.Meanwhile, individualization propaganda and education should be conducted to different crowds to improve the knowledge level of venous transfusion for the patients. In addition, the self-care of venous transfusion should be conducted well to reduce the risk of venous transfusion. Key words: Venous transfusion; Cognitive status; Health education; Investigation

Changes in tensile properties of needle thread in lock stitch sewing

Sewing threads of different structures are analyzed for the loss in tensile properties of threads in sewing on a single needle lock stitch machine. The needle threads suffer greater loss in tensile properties than the bobbin threads in sewing, mainly due to abrasion at needle eye, which can cause structural damage to thread and fibre damage; both depend on the thread structure and inherent strength of fibres. The spun and core spun threads undergo both structural damage and rupture of surface fibres due to abrasion in sewing. The nylon filament threads, due to their better abrasion resistance suffer lesser loss in tenacity and breaking extension in sewing compared to polyester threads. The spun threads, having coarser fibres help in retaining the thread strength in sewing; whereas high tenacity filaments would be useful in the case of core spun and filament threads, Thread cyclic loading/dynamic tension on needle thread during sewing does not affect the strength of the threads under study significantly; however, it affects the initial modulus of few threads, especially the nylon and spun threads.

A challenging case of transvenous lead extraction

A 72-year-old male patient with a 7-year history of cardioverter-defibrillator (ICD) implantation was admitted to our clinic with pocket infection. One year prior to this admission, he had undergone an unsuccessful extraction procedure at another clinic, during which the older broken ICD lead had been left in place and a newer ICD lead implanted via the same pocket. The newer and older leads were extracted by mechanical dilator sheath and needle eye snare respectively.

Percutaneous lead extraction by femoral approach, case report

BackgroundTransvenous lead extraction is usually done via subclavian route, here we present an extraction case performed by femoral approach. Case report72year old patient who has a VVI pacemaker with one passive fixation and one active fixation lead admitted to our clinic with pacemaker decubitus. We decided to remove all hardwares and insert a new battery and lead on contralateral side. However the first passive lead was deep inside the subclavian region so we planned to use femoral approach for lead extraction if subclavian approach fails in the patient. In the catheterization laboratory active fixation lead is easily explanted by simple traction but the passive lead could not be reached by subclavian approach. We decided to use the femoral Byrd Workstation 12F™ and Needle's eye Snare® to extract lead femorally. The lead is snared at subclavian end and is extracted by applying gentle simple traction and taken into the femoral Byrd Workstation 12F™. We implanted new pacemaker at contralateral side and discharged patient uneventfully. ConclusionPercutaneous femoral approach for lead extraction is generally used as bail-out procedure for leads that cannot be extracted by subclavian approach but as in our case it can be used primarily according to the clinical presentation of the patient.

Needle Penetration Through Polymeric Cellular Foam Materials

This article presents an analytical model for predicting the needle penetration force through relatively hard polymeric cellular foam. Prediction of needle penetration force is of importance to a number of applications, including textile and composites manufacture as well as robotic surgery. With the aid of this analytical model, a complete nonlinear force-displacement relation can be predicted for any needle size, material hardness, thickness, or inclination. The model assumes the needle to be a cylinder with a conical tip and ignores features, such as needle eye. The primary mechanism for needle penetration force is cell crushing while the friction between the needle and the foam plays a secondary role. There is a good agreement between the experimental and analytical force-displacement curves. In comparison to numerical methods that require nonlinear finite element analysis, this analytical model can be implemented with the knowledge on only two material properties: compression strength and frictional resistance.

The Needle's Eye: Wealth and Western Society from the Late Roman Empire to the Early Middle Ages

This review article discusses Peter Brown, Through the Eye of a Needle: Wealth, the Fall of Rome, and the Making of Christianity in the West, 350-550AD (pp. xxx + 759, 16 col. plates; Princeton University Press; Princeton, NJ, 2012). Following an overall view of the book (I), this essay makes observations about the handling of late Roman social structures (II), about the implications of the geographical emphases of the book (III) and about the implications of the judgments it offers on the chronology of the transition from late antiquity to the early middle ages (IV). This essay also comments on literary methods and their role in Brown’s exposition (V) and offers a concluding reflection on the kind of historical craftsmanship exemplified by the book (VI).

Prevalence of venous occlusion in patients referred for lead extraction: implications for tool selection.

Data concerning the incidence of venous obstruction in patients referred for lead extraction is limited. Thus, we aimed to assess the incidence of venous obstruction in patients referred for lead extraction and the implications for tool selection. Contrast venography of the access vein was obtained in 202 patients (147 men; mean age, 62.4 ± 14.5 years) scheduled for lead extraction. The indication for lead extraction included infection (n = 145, 72%) and other causes (n = 57, 28%). Two patients with device infection had superior vena caval occlusion. Access vein occlusion occurred in 6 (11%) patients without infection vs. 46 (32%) patients with infection [P = 0.002; odds ratio (OR) 3.94; 95% confidence interval (CI) 1.58-9.87]. No significant differences between occluded and non-occluded patients were seen for age, sex, device type, number of leads, time from implant of the initial lead, or anticoagulation therapy (all P>0.05). Procedural duration and fluoroscopy exposure time were significantly lower in the open group than in the occluded group (P < 0.05). Patients with venous occlusion required more advanced tools for lead extraction, such as dilator sheaths, evolution sheaths, and needle's eye snares (P = 0.019). Both systemic and local infections are associated with increased risk of access vein occlusion. We found no support for the hypothesis that venous occlusion increases with the number of leads present. Lead extraction was more difficult in patients with venous occlusion, requiring advanced tools and more time.

Dynamics of lockstitch sewing process

During high speed sewing, the needle thread is exposed to dynamic loading, short strike loading, inertia forces, friction, rubbing, force of check spring, bending, pressure, friction, impact, shock and thermal influence. The dynamic thread loading/tension alters throughout the stitch formation cycle and along its passage through the machine. The greatest tensile force occurs at the moment of stitch stretching, when the take up lever pulls for required thread length through the tension regulator. These stresses act on the thread repeatedly and the thread passes 50-80 times through the fabric, the needle eye and the bobbin case mechanism, before getting incorporated into the seam, which result in upto 40% loss in tensile strength of the sewing thread. This damage in the sewing thread adversely affects its processing and functional performance. In this paper, the contribution of dynamic loading, passage through needle and fabric, and bobbin thread interaction in the loss in tensile properties has been studied. It is observed that the loss in tensile properties occurs mainly due to the bobbin thread interaction. Dynamic loading due to the action of take up lever also causes substantial loss in tenacity and breaking elongation of cotton threads.