The rapid urbanization and population growth in major cities have given rise to enduring urban challenges, prompting local governments to assess urban development performance and customize urban planning strategies to meet these challenges. This study aims to formulate an evaluation framework for the comprehensive efficiency of major cities, centering on governance, Information and Communication Technology (ICT), and sustainability as fundamental aspects. Distinct from prior research, the framework employs the network slack-based measure (SBM) to unravel efficiency, concurrently scrutinizing input/output slack and link efficiency. Utilizing the network SBM model, the study assesses the comprehensive operational efficiencies of 38 major Chinese cities spanning from 2015 to 2019. The application of the Kruskal–Wallis test discerns differences in comprehensive efficiency between coastal and inland areas. The results indicate that governance, ICT, and sustainability significantly influence the comprehensive operations of cities. In addition to general and short-term policies, the implementation of the National New-Type Urbanization Plan by the Chinese central government has led to an increase in the number of cities demonstrating sustainable efficiency. Despite fluctuations in the efficiency gap during the study period, coastal cities consistently outperform their inland counterparts in terms of efficiency. Persistent geographical disparities underscore the imperative for balanced development. While acknowledging positive strides in sustainable urbanization, the study emphasizes the ongoing necessity to address the adverse impacts of urban development, positioning governance, ICT, and sustainability as indispensable elements in confronting the multifaceted challenges inherent in urban development. The research findings contribute significantly to the field of urban efficiency evaluation, accentuating the collaborative impact of governance, ICT, and sustainability.