AbstractPersons with disabilities (PwDs) face a disproportionately high risk due to their physical or mental limitations and socioeconomic barriers during emergencies. To better understand and empower PwDs for disaster preparedness, this study used an updated national representative survey (2021 Federal Emergency Management Agency National Household Survey) from the United States to examine the differences between PwDs and their counterparts concerning disaster preparedness with the guidance of the protection motivation theory. The results of the Tobit regression models indicated that being disabled was negatively correlated with the level of preparedness. Furthermore, disability status significantly and negatively modified the relationship between risk perception and disaster preparedness. Likewise, self‐efficacy was less strongly correlated with preparedness activities if people self‐reported themselves as having a disability. Moreover, for people with disabilities, their beliefs about the effectiveness of preventive behaviours (response efficacy) predicted decreased adoption of preparedness measures. Promoting disaster risk reduction education, strengthening self‐efficacy and developing more inclusive and targeted intervention strategies for PwDs can be used to improve their preparedness degree and capacity for disaster prevention.