National Academy Of Sciences Research Articles

Supporting the Well-Being of Children and Youth With Special Health Care Needs: NASEM Proceedings.

Children and youth with special health care needs (CYSHCN) are living longer than ever. These advances come with a price: Patients, families, communities, and systems must absorb the challenges of chronic caregiving, including protracted stress and poor mental health. In 2023, the National Academies of Science, Engineering, and Medicine convened thought-leaders for conversations about supporting the emotional well-being of CYSHCN and their families. Invited panelists included 2 parents and 3 academic pediatricians. Parents suggested opportunities for clinicians and systems to better support CYSHCN. Clinicians described work focused on:Individual patient- and family-level resilience: Defined as a process of harnessing resources to sustain well-being in the face of stress, resilience is learnable. Programs that teach people to identify and bolster "resilience resources" show promise in improving child and caregiver mental health;Clinician- and practice-level provision of care: Individual-level interventions are only effective if clinicians know when and how to deliver them. Hence, the American Board of Pediatrics created and demonstrated the success of a "roadmap" to support routine screening for and discussion of social and emotional health needs; andSystems-level barriers: Even with patient-level programs and clinician-practice guidance, unmet social and mental health needs persist. Accessing and coordinating services is difficult, may not be covered by insurance, and historically marginalized populations are the least likely to benefit. Together, the panel underscored a critical fact: We cannot optimize child and family well-being without focusing on patients, caregivers, clinicians, and systems.

Child Health Care at a Crossroads—A Report From the National Academies of Sciences, Engineering, and Medicine

This Viewpoint discusses changes needed at local, state, and national levels to improve child health care.

Past, Present, and Future of RNA Modifications in Infectious Disease Research.

In early 2024, the National Academies of Sciences, Engineering, and Medicine (NASEM) released a roadmap for the future of research into mapping ribonucleic acid (RNA) modifications, which underscored the importance of better defining these diverse chemical changes to the RNA macromolecule. As nearly all mature RNA molecules harbor some form of modification, we must understand RNA modifications to fully appreciate the functionality of RNA. The NASEM report calls for massive mobilization of resources and investment akin to the transformative Human Genome Project of the early 1990s. Like the Human Genome Project, a concerted effort in improving our ability to assess every single modification on every single RNA molecule in an organism will change the way we approach biological questions, accelerate technological advance, and improve our understanding of the molecular world. Consequently, we are also at the start of a revolution in defining the impact of RNA modifications in the context of host-microbe and even microbe-microbe interactions. In this perspective, we briefly introduce RNA modifications to the infection biologist, highlight key aspects of the NASEM report and exciting examples of RNA modifications contributing to host and pathogen biology, and finally postulate where infectious disease research may benefit from this exciting new endeavor in globally mapping RNA modifications.

Enhancing Temporomandibular Disorders Education for Initial Care Clinicians Through Interprofessional Education.

Temporomandibular disorders (TMDs) are common musculoskeletal pain conditions that can significantly impact daily activities such as eating, talking, breathing, intimacy, and expressing emotion. TMDs are often complex and multifactorial, and many patients experience overlapping pain conditions, sleep difficulties, and mental health challenges. The National Academies of Sciences, Engineering and Medicine (NASEM) has called for improved TMD education and training for health professionals, as current training opportunities are limited. To prepare health professionals to care for patients who have a TMD, we designed a 5-hour, interactive, module-based curriculum aligned with the 2020 NASEM recommendations. The four-part module set addresses TMD physiology and pathophysiology, assessment, diagnosis, and management. Instructional methods are founded on the Cognitive Theory of Multimedia Learning and include engaging videos, clinical evaluation and education tools, and interactive digital simulation scenarios. Thirty learners from diverse health professional backgrounds (medicine, dentistry, physician assistant, nursing, physical therapy) participated. Multiple-choice question assessments and pre/post retrospective survey scores demonstrated enhanced knowledge (M = 2.9 vs. M = 4.2, p < .001) and perceived competence (M = 1.9 vs. M = 3.4, p < .001), respectively. Encouragingly, all participants indicated applicability to their clinical practice. Our modules offer educators and clinicians a valuable resource to improve TMD knowledge and facilitate best practices. Supplementary resources included in the curriculum are conducive to clinical implementation, fostering improved clinician assessment and patient education.

A Scoping Review of Implementation Science Studies in the Field of Traumatic Brain Injury: State of the Science and Future Directions.

Implementation research is essential to accelerating the public health benefits of innovations in health settings. However, the US National Academies of Sciences, Engineering, and Medicine 2022 report identified a lag in published implementation research applied to traumatic brain injury (TBI). Our objectives were to characterize implementation science studies published to date in TBI clinical care and rehabilitation and provide recommendations for future directions. A scoping review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews. Articles published between 2011 and 2023 were identified (MEDLINE, PubMed, PsychInfo, and Web of Science), and included if the study focused on the TBI population, measured at least one Proctor (2011) implementation outcome and aligned with implementation research designs. Data were charted using an extraction template. Of the 38 articles, 76% were published between 2018 and 2023. About 37% of articles were in the pre-implementation phase, and 57.9% were in the implementation phase. Over half of articles used a theory, model, or framework to guide the research. Fifteen studies were descriptive, 10 were qualitative, 7 were mixed methods, and 4 were randomized controlled trials. Most studies investigated implementation outcomes regarding national guidelines following TBI or TBI symptom management. Adoption (42.1%) and fidelity (42.1%) were the most commonly studied implementation outcomes, followed by feasibility (18.4%), acceptability (13.2%), and penetration (10.5%). Only 55% of studies used or tested the effectiveness of one or more implementation strategies, with training and education used most commonly, followed by data warehousing techniques. Future research should prioritize the selection and investigation of implementation strategy effectiveness and mechanisms across contexts of care and use implementation research reporting standards to improve study rigor. Additionally, collaborative efforts between researchers, community partners, individuals with TBI, and their care partners could improve the equitable translation of innovations across service contexts.

The Essential Role of Primary Health Care for Health Security.

In July 2023, primary health care experts from more than 20 countries, the World Health Organization (WHO), and most agencies within the US Department of Health and Human Services (HHS) met at the National Academy of Sciences in Washington, DC, to catalyze action toward revitalizing primary care in the United States align efforts to advance primary health care worldwide, and improve health and security for all.1 This meeting was informed by the NASEM's critical primary care report, which highlighted the need for federal leadership to strengthen primary care services in the United States, especially for underserved populations, and to inform primary care systems around the world. To that end, this meeting was designed to explore the challenges and opportunities of investing in primary health care as a common good and critical for health security and resilience across the globe.2 In this issue, you will find {number} special communications from this conference that highlight the need to evolve from primary care to primary health care, the importance of primary care and public health collaboration, and the necessity for ongoing external scientific expertise to inform US federal government coordination efforts.Despite the clear consensus among global stakeholders regarding the importance of Primary Health Care to health equity, behavioral health, health security, and pandemic resilience, a year later the anticipated HHS Action Plan to guide implementation of the NASEM primary care recommendations has yet to be launched. While some agencies are moving ahead with initiatives and programs within their purview, the lack of a Primary Care Action Plan remains a missed opportunity to coalesce politically powerful stakeholders around a united and much-needed vision for a US health system centered on Primary Health Care, particularly in light of our challenges in responding to COVID-19.

Potential Applications and Ethical Considerations for Artificial Intelligence in Traumatic Brain Injury Management.

Artificial intelligence (AI) systems have emerged as promising tools for rapidly identifying patterns in large amounts of healthcare data to help guide clinical decision making, as well as to assist with medical education and the planning of research studies. Accumulating evidence suggests AI techniques may be particularly useful for aiding the diagnosis and clinical management of traumatic brain injury (TBI)-a considerably heterogeneous neurologic condition that can be challenging to detect and treat. However, important methodological and ethical concerns with the use of AI in medicine necessitate close monitoring and regulation of these techniques as advancements continue. The purpose of this narrative review is to provide an overview of common AI techniques in medical research and describe recent studies on the possible clinical applications of AI in the context of TBI. Finally, the review describes the ethical challenges with the use of AI in medicine, as well as guidelines from the White House, the Department of Defense (DOD), the National Academies of Sciences, Engineering, and Medicine (NASEM), and other organizations on the appropriate uses of AI in research.

Artificial intelligence in food and nutrition evidence: The challenges and opportunities based on a convening of content experts

Abstract Science-informed decisions are best guided by the objective synthesis of the totality of evidence around a particular question and assessing its trustworthiness through systematic processes. However, there are major barriers and challenges that limit science-informed food and nutrition policy, practice, and guidance. First, insufficient evidence, primarily due to acquisition cost of generating high-quality data, and the complexity of the diet-disease relationship. Furthermore, the sheer number of systematic reviews needed across the entire agriculture and food value chain, and the cost and time required to conduct them, can delay the translation of science to policy. Artificial intelligence (AI) offers the opportunity: 1) to better understand the complex etiology of diet-related chronic diseases; 2) to bring more precision to our understanding of the variation among individuals in the diet-chronic disease relationship; 3) to provide new types of computed data related to the efficacy and effectiveness of nutrition/food interventions in health promotion; and 4) to automate the generation of systematic reviews that support timely decisions. These advances include the acquisition and synthesis of heterogeneous and multimodal datasets. This perspective summarizes findings from a meeting of experts convened at the National Academy of Sciences, Engineering and Medicine. The purpose of the meeting was to examine the current state and future potential of AI in generating new types of computed data as well as automating the generation of systematic reviews to support evidence-based food and nutrition policy, practice and guidance.

Serum per- and polyfluoroalkyl substance (PFAS) levels and health-related biomarkers in a pilot study of skiers in New England

BackgroundPer- and polyfluoroalkyl substances (PFAS), synthetic chemicals with adverse health effects, are used extensively in consumer products. Ski waxes, applied to the base of skis, contain up to 100% PFAS by mass, but exposure and health effects are poorly characterized. ObjectivesOur objectives were to quantify serum PFAS concentrations among skiers and explore associations with reported ski wax use and biomarkers of cardiometabolic, thyroid, and immune health. MethodsWe recruited 30 active adult skiers to provide non-fasting blood samples and complete questionnaires. We quantified 18 PFAS using mass spectrometry, and measured serum lipids, thyroid hormones, and immunoglobulins. We explored associations of individual and aggregate measures of serum PFAS with wax use indicators and health biomarkers using multivariable regression models, adjusted for age and gender identity. ResultsNine PFAS (PFBS, PFHpS, PFHxS, Sm-PFOS, n-PFOS, PFDA, PFNA, PFUnDA, n-PFOA) were detected in 100% of participants, and MeFOSAA in 93%. Compared to NHANES, median serum concentrations (ng/ml) were similar, but higher in coaches (e.g., PFOAall: 1.1, PFOAcoaches: 2.7, PFOANHANES: 1.2; PFNAall: 0.5, PFNAcoaches: 1.7, PFNANHANES: 0.4). Factors reflecting wax exposure were positively associated with PFAS: e.g., >10 years as a snow sport athlete, compared to ≤10 years, was associated with 3.2 (95% CI: 0.7, 5.6) ng/ml higher aggregate PFAS, as defined by National Academies of Science, Engineering, and Medicine (NASEM). An IQR (6.3 ng/ml) increase in NASEM PFAS was associated with 32.1 (95% CI: 7.0, 57.2), 35.5 (13.5, 57.5), and 12.8 (0.6, 25.1) mg/dl higher total cholesterol, LDL-C, and sdLDL-C, respectively. DiscussionOur study provides early evidence that recreational skiers, particularly coaches, are exposed to PFAS through ski wax. Several PFAS were associated with higher serum lipids among these physically active adults. Interventions to remove PFAS from fluorinated wax could decrease direct exposure to skiers and reduce PFAS release into the environment.

Overcoming the Impact of Students for Fair Admission v Harvard to Build a More Representative Health Care Workforce: Perspectives from Ending Unequal Treatment.

Policy Points In a recently commissioned report on solutions for eliminating racial and ethnic health care inequities entitled Ending Unequal Treatment, the National Academies of Sciences, Engineering, and Medicine found a health workforce that is representative of the communities it serves is essential for health care equity. The Supreme Court decision to ban race-conscious admission constraints pathways toward health workforce representativeness and equity. This paper draws on the National Academies report's findings that health care workforce representativeness improves care quality, population health, and equity to discuss policy and programmatic options for various participants to promote health workforce representativeness in the context of race-conscious admissions bans.

Delivering High-Quality Cancer Care: Charting a New Course for a System in Crisis: One Decade Later.

In 2012, the National Academies of Sciences, Engineering, and Medicine convened a committee charged with addressing the quality of cancer care in the United States and providing recommendations to policymakers and the cancer care community on strategies to improve cancer care delivery from the time of diagnosis through end-of-life. The resulting committee report, titled Delivering High-Quality Cancer Care: Charting a New Course for a System in Crisis (2013), presented a conceptual framework that included six interconnected components of care with corresponding recommendations. Over the past decade, the delivery of high-quality of cancer care has become more challenging and increasingly demanding on the workforce. In this manuscript, we review the goals and recommendations made in 2013, describe progress to date, and offer insights into future dedicated efforts and/or new strategies needed to achieve high-quality cancer care.

Orofacial Pain.

This article explores the multiple etiologies, diagnosis, and management of orofacial pain. Published in 2019, the International Classification of Orofacial Pain has become the internationally accepted classification system for primary and secondary facial pain. New discoveries in temporomandibular disorders have demonstrated that they are far more complex than the traditional dental mechanistic point of view. A 2020 consensus report released by the National Academies of Sciences, Engineering, and Medicine entitled "Temporomandibular Disorders: Priorities for Research and Care" highlighted this paradigm shift and its importance for patient care, education, and research. Orofacial pain comprises many disorders with different etiologies and pathophysiologies. The subjectivity of the pain experience and the interrelated anatomy and physiology of the craniofacial area add to the complexity of diagnosis when the source and etiology of pain are not clear. As orofacial pain straddles the expertise of multiple disciplines, a multidisciplinary approach combining medication, physical therapy, and procedural and psychological strategies is essential in treating patients with orofacial pain.

Urban Traffic Identification by Comparing Machine Learning Algorithms

The Internet of Things (IoT) applied to intelligent transport systems has become a key element for understanding the way traffic flow behaves in cities, which helps in decision-making to improve the management of the transport system by monitoring and analyzing network traffic in real time, all with the aim of daily benefiting users of the city’s road infrastructure. Traffic volume estimation in real time, with high effectiveness, may help mobility management and improve traffic flow. Moreover, machine-learning algorithms have shown effectiveness in various scientific fields and have provided a significant platform for achieving intelligent applications. Therefore, we applied various machine learning algorithms to classify the vehicular traffic status in the traffic network of two cities with more than 2 million inhabitants. It was first necessary to establish, from the attributes provided by the datasets, the object class from the LOS (Level of Services) thresholds proposed by the National Academies of Sciences, Engineering, and Medicine, for the basic segments of highways in an urban area. We then selected the attributes of interest using the Recursive Feature Elimination Method (RFE) to reduce the dimensionality of the data, and applied the DT, RF, ET, KNN, and MLP algorithms to train and classify the level of vehicular congestion, defining various volumes of training and validation data. The results show the high effectiveness of the algorithms, highlighting the MLP algorithm as the one that provides the highest effectiveness on average for the evaluated datasets, with a mean precision of 99.5%.

On the Anniversary of the Academician of the National Academy of Sciences of Belarus Stanislav Ivanovich Grib

Stanislav Ivanovich Grib, Doctor of Agricultural Sciences, Professor, an Honored Scientist of the Republic of Belarus, a Laureate of the State Prize of the Republic of Belarus, an Academician of the National Academy of Sciences (NAS) of Belarus, a Foreign Member of the Russian Academy of Sciences and the National Academy of Agrarian Sciences of Ukraine, a talented Belarusian scientist in the field of plant breeding, known in the country and abroad, the leader of the Belarusian scientific school in the area of breeding and seed production, an experienced organizer of agricultural science, turned 80 years old on August 6, 2024. He was the first in Belarus to scientifically substantiate and implement in practice a new scientific direction, that is, breeding of intensive varieties of grain crops with a yield of 10-12 t/ha of grain; developed methods for broadening genetic diversity and identifying genotypes that combine high productivity and good product quality with tolerance to biotic and abiotic environmental factors; substantiated the parameters of the model of intensive varieties; created and introduced into production systems of highly productive, resource-saving varieties of barley, triticale, and spring wheat. The results of his research have been published in more than 700 scientific works, including 12 monographs, books and textbooks. Stanislav Ivanovich is the author of eight inventions and 89 varieties of agricultural plants. Academician S.I. Grib, the leader of the scientific school of plant breeding in Belarus, trained four doctors and twelve candidates of science. S.I. Grib's achievements have been recognized abroad. He was elected a foreign member of the Russian Academy of Sciences and the National Academy of Agrarian Sciences of Ukraine, an Honorary Professor of the Siberian Branch of the Russian Academy of Sciences, a member of the European Association of Plant Breeders (EUCARPIA), and an Honorary Doctor of the Belarusian Agricultural Academy (BSAA). Stanislav Ivanovich was awarded the Order of the Badge of Honor, a diploma of the Supreme Council of the BSSR, medals and diplomas of the Exhibition of Economic Achievements, honorary diplomas of the National Academy of Sciences of Belarus, the Ministry of Agriculture and Food of the Republic of Belarus, and the Scientific and Practical Center of the National Academy of Sciences of Belarus for Agriculture.

Development, validation, and clinical assessment of a liquid chromatography-tandem mass spectrometry serum assay for per- and polyfluoroalkyl substances (PFAS) recommended by the National Academies of Science, Engineering, and Medicine (NASEM)

Per- and polyfluoroalkyl substances (PFAS) are widely used in industry, residential, and consumer products. Studies have shown associations between high PFAS exposure and adverse health effects. In 2022, the National Academies of Science, Engineering, and Medicine (NASEM) published Guidance on PFAS Exposure, Testing, and Clinical Follow-up providing laboratory and clinical direction. The Guidance suggests nine PFAS should be measured in serum or plasma specimens and summed to provide a total PFAS concentration using a NASEM-recommended method. Follow-up clinical recommendations are based on the calculated PFAS NASEM summation. We developed and validated a liquid chromatography-tandem mass spectrometry (LC–MS/MS) method in accordance with NASEM recommendations but distinguished by the ability to separate closely related structural isomers. As part of our validation, PFAS prevalence was evaluated in a population survey comprised of clinical donor and remnant specimens (n = 1023 in total). In this study, 82.2% of the specimens had PFAS NASEM summations of 2 to < 20 ng/mL and 2.5% had a summation ≥ 20 ng/mL. The median PFAS NASEM summation was 4.65 ng/mL in this study, lower than the 7.74 ng/mL median observed in the 2017–2020 Centers for Disease Control and Prevention, National Health and Nutrition Examination Survey (n = 3072). This lower median PFAS NASEM summation may reflect a decline in PFAS population levels over time or sample population exposure differences.Graphical

63 Impacts of protein supplementation frequency on animal performance, rumen fermentation and methane emission from growing beef cattle

Abstract Nutrient supplementation is one of largest expenditure in forage-based beef production systems, especially when forage quality is poor or limited. Decreasing supplementation frequency may have a role in improving sustainability by increasing animal performance and minimizing cost of labor and fuel. This study evaluated the impacts of protein supplementation frequency (canola meal pellet; CMP) on animal performance, rumen fermentation, and enteric methane production from beef cattle fed forage-based diet. A total of 60 crossbred backgrounding steers [body weight (BW) = 278 ± 10 kg) was randomly assigned to one of the three treatments (n = 20/treatment): i) control (no CMP supplementation), ii) control + everyday CMP supplementation (0.83 kg/d per steer), and iii) control + every other day supplementation of CMP. The study was comprised of 21 d of adaptation followed by three 21-d periods, with enteric methane measured for 7 d per period. Animals were fed grass hay-based diets once a day at 0800 h and remained on their respective diets throughout the 63-d study. Diets were formulated considering animal BW, feed nutrient density and environmental condition in accordance with the National Academies of Sciences, Engineering and Medicine. Each treatment group was assigned to a pen, with the cattle and diets rotated among pens weekly to allow the animals to access the GreenFeed system stationed in one of the pens for enteric methane measurement. For measurement of rumen fermentation products, three ruminally canulated steers (BW = 350 ± 20 kg) were allocated to the three treatments using a 3 x 3 Latin Square Design with 21-d periods so that one animal received all the treatments over the three experimental periods. Animals were adapted to the treatments for 17 d and rumen samples were collected between d 19 and 21 at 0700 h, 1000h, 1300 h, 1600 h and 1900 h. Data were analyzed using the Mixed procedure of SAS. Relative to the control treatment (9.9 kg/d), DM intake was 4 to 5% greater (P &amp;lt; 0.001) following CMP supplementation regardless of supplementation frequency. Similarly, average daily gain was greater (7 to 11%, P = 0.01) for CPM supplemented treatments as compared with control (1.04 kg/d) irrespective of supplantation frequency. Rumen fermentation was affected by treatments. Total VFA concentration was greater (P = 0.01) for the every other day supplementation of CMP as compared with control and daily supplementation treatments. Conversely, rumen ammonia concentration was not affected by treatments. The control group had greater acetate and reduced propionate molar proportions that resulted in a 5 to 6% greater acetate:propionate ratio (P &amp;lt; 0.01) as compared with the CMP supplemented groups. Enteric methane production (g/d) was greater for the daily CMP supplementation (P = 0.02) while yield (g/kg daily weight gain) was not affected by treatment. Our results indicated that reduction of protein supplementation frequency improved animal performance without negatively impacting rumen fermentation.

Climate Science, the Military-Industrial Complex, and the Political Economy of Knowledge-Making: Beyond the Capitalist Ontology of Nature?

Climate science is one of the main political drivers of today's world, informing critical scholars and social movements alike. Yet, many scholars associate it with projects of domination (the Cold War, capitalism, imperialism) while relying on it to elaborate a critique of capital. This article proposes a new historical account of climate science. Drawing from archival findings, interpreted with historical sociology combined with the critique of political economy, the article shows that a conflict developed at the National Academy of Sciences during the Vietnam War, between scientists who wanted atmospheric research to be under the auspices of NATO, as proposed by the "father of the H-bomb" Edward Teller, and others who favored global cooperation, led by meteorologist Jule Charney. The resolution of this conflict had consequences for both the institutional framework and the content of what is today understood as climate science. It is argued that this conflict was part of the social movements of the time, and had momentous consequences for knowledge-making by rejecting the association of atmospheric science with the military-industrial complex, an essential component of capitalist accumulation. Most notably, it resulted in the conceptualization of the atmosphere as a commons, which undermines its treatment as a sink, private property, or commodity, and qualifies it as a potential informer of the allocation of resources in an emancipated society. Therefore, the article sheds light on the resonance between climate science and current social movements and critical scholars: the constitution of climate science was in mediation with a worldview that was critical of aspects of the capitalist political economy and its ontology of nature.

How interdisciplinary is it? A new method for quantifying interdisciplinarity in student teams & examination of a large project-based program

ABSTRACT The European Higher Education Area and the US National Academies of Science, Engineering, and Medicine have called on higher education to support interdisciplinary learning. The National Academies recommend evaluating interdisciplinary education against relevant criteria, but beyond listing student majors, institutions cannot easily quantify interdisciplinarity in education. The Rao-Stirling diversity index, which incorporates measures of cognitive distance, is used to quantify the interdisciplinarity of research. This study extends the use of the Rao-Stirling diversity index to the context of higher education to: (1) determine whether it provides a more nuanced measure of interdisciplinarity than number of majors, and (2) to examine patterns in interdisciplinarity across 79 student teams in Georgia Tech’s Vertically Integrated Projects Program (N = 1218). The analysis employed cognitive distances developed in a previous study. Distributions of diversity indexes and enrollment by major were examined across the program, along with visualizations for 4 teams. Results show the Rao-Stirling diversity index provided a more comprehensive measure of team interdisciplinarity, and it indicated higher interdisciplinarity in more teams and in comparatively smaller teams than the number of majors would imply. Indexes across the program were examined graphically and explored through regression. Results indicated that higher interdisciplinarity was associated with smaller team size, implying a possible need for additional support for these teams. The utility of the index in quantifying the interdisciplinarity of teams and in revealing a previously unknown pattern confirm its usefulness within the context of higher education. Limitations, implications for research and practice, and future directions are discussed.

Wastewater Target Pathogens of Public Health Importance for Expanded Sampling, Houston, Texas, USA.

Building on the success of initiatives put forth during the COVID-19 pandemic response, US health officials are expanding wastewater surveillance programs to track other target pathogens and diseases of public health interest. The Houston Health Department in Houston, Texas, USA, conducted a hypothesis-generating study whereby infectious disease subject matter experts suggested potential targets. This study addressed 2 criteria recommended by the National Academies of Sciences, Engineering, and Medicine for selecting wastewater targets. Results can be used as a basis of a questionnaire for a future population-based study to recommend targets of highest priority to include for expanded wastewater sampling.

Through the secret gate: a study of member-contributed submissions in PNAS

This work studies “Contributed” articles in the Proceedings of the National Academy of Sciences of the United States of America (PNAS), a streamlined submission track for members of the US National Academy of Sciences (NAS). We assess the characteristics and impact of those articles and the background and status of their authors, by comparing these articles to PNAS articles following the traditional editorial process. Analyzing over 46,000 articles published between 2007 and 2020, we find: Firstly, and perhaps most centrally, (1) Contributed articles generally appear in lower per-author citation deciles than Direct submissions, but are more likely to appear in the overall top citation deciles of authors; (2) PNAS-Contributed articles tend to spend less time in the review process than Direct submissions; (3) Direct submissions tend to be slightly higher cited than Contributed articles, which are particularly overrepresented amongst least-cited PNAS papers. Disciplinary differences were negligible; (4) authors with lower mean normalized citation scores are profiting most from articles published as Contributed papers, in terms of citation impact; (5) NAS members tend to publish most Contributed articles in the first years after becoming an NAS member, with men publishing more of these articles than women; (6) Contributing authors take up a unique niche in terms of authorship roles, mainly performing supervisory and conceptualisation tasks, without the administration and funding acquisition tasks usually associated with last authors.