With the plethora of recent literature suggesting lesser invasive treatment modalities for keratocystic odontogenic tumour (KCOT), we publish our observations in 19 cases treated with marsupialisation at first stage followed by removal of lesion and overlying mucosa at the second. The age of patients ranged from 24 to 47 years with a predominant male predilection. All these cases were diagnosed by an incisional biopsy. For mandibular cystic tumours, a window was created in the alveolus and a sterile radiopaque tube was inserted and sutured in place. Maxillary lesions were accessed via vestibular incision and nasal antrostomy was performed following which antiseptic paraffin soaked ribbon gauze was placed and tailed into the nasal cavity for removal at three weeks. After a mean follow-up of five months (range, four to nine months), the remaining lesion was removed along with the overlying mucosa (for mandibular lesions only). These cases were further followed on three-monthly regular visits (eight months to four and a half years). Bone fill as well as recurrence was assessed. In two cases, the lesion recurred and was enucleated and peripheral ostectomy was performed. In one of these recurring lesions, transformation into plexiform ameloblastoma was recorded. Although the follow-up period is limited, the results predict a promising response.
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