Nanocontainers Research Articles

Role of nanoparticles in maintaining food safety and tackling malnutrition

The food varieties which complete what seems like a forever cycle from development to bundling through nanotechnology are known as Nano food, for instance, we are devouring some braced food that has nanoparticles like iron, zinc, omega 3, and coenzymes. Numerous food sources normally having safe nanoparticles, get processed in the body at the nanoscale. Nano food sources have high dietary benefits and less bad cholesterol. They are the cutting-edge food that may battle against Malnutrition. There are more than 500 nano foods accessible in the market which can be sorted as Nanoemulsion, Nano container, and bundled food. Nanoparticles are additionally utilized as a protected palatable covering that monitors our food against parasite, dampness, and gas trade in this way expanding the self-existence of food. Nanoparticles have an extraordinary job in food bundling.

Personalized demand-responsive biphasic microneedle patch for smart drug administration.

Many patients, especially those with chronic diseases, would benefit from personalized drugs that could modulate the treatment regimen. Tailored drug delivery via microneedle patches (MNPs) has emerged as a promising technology to address this problem. However, it is still difficult to modulate the treatment regimen in one MNP. Here, multiple treatment regimens were achieved by the same MNP functionalized with modifiable nanocontainers (NCs). The MNPs were biphasic in design, resulting in approximately a twice as high drug loading capacity than that of traditional dissolving MNPs. The drug-loaded NCs could have a zero-order release rate for at least 20 d in vitro. Furthermore, three model MNPs, Type-A (100% drug), Type-B (50% drug and 50% NCs) and Type-C (100% NCs) were generated to simulate various personalized dosing needs. In vivo application of these models could achieve effective therapeutic drug concentrations in the first 12 h and adjusted the duration of effective drug action from 24 h to 96 h and 144 h, respectively, with outstanding biocompatibility. These findings indicate that this device holds significant promise for personalized drug delivery.

Erosive tooth wear inhibition by hybrid coatings with encapsulated fluoride and stannous ions

This study aimed to formulate a hybrid coating material (HC) and to modify this HC with fluoride (NaF) and stannous (SnCl2) ions, directly or encapsulated in nano containers, testing the effects of these materials against dental erosion and erosion–abrasion. Enamel and dentin specimens were treated with the HCs, and then tested in erosion or erosion–abrasion cycling models of 5 days (n = 10 for each substrate, for each model). Deionized water was the negative control, and a fluoride varnish, the positive control. Surface loss (SL, in µm) was evaluated with an optical profilometer, and data were statistically analyzed (α = 0.05). For enamel, in erosion, the positive control and HC without additives showed significantly lower SL than the negative control (p = 0.003 and p = 0.001). In erosion–abrasion, none of the groups differed from the negative control (p > 0.05). For dentin, in erosion, the positive control, HC without additives, HC with non-encapsulated F, and HC with encapsulated F + Sn showed lower SL than the negative control (p < 0.05). In erosion–abrasion, none of the groups differed significantly from the negative control (p < 0.05). HC without additives showed a promising potential for protecting the teeth against dental erosion (with upward trend for improved protection on dentin), but not against erosion–abrasion. The presence of additives did not improve the protective effect of the HC, on both substrates.

Dendrimer like mesoporous silica nano container (DMSN) based smart self healing coating for corrosion protection performance

A new generation smart self-healing coating possessing both passive matrix functionality and rapid response to local changes in the environment is of great industrial importance. In the present work, a stimulus responsive smart self -healing anticorrosion coating was developed based on acrylic resin, incorporated with Dendrimer like Mesoporous Silica Nanoparticles (DMSN) loaded inside with 8-hydroxyquinoline inhibitor. FESEM and TEM analysis showed that the dendrimer like mesoporous silica (DMS) nanoparticles synthesized were of spherical and fibrous form with size less than 200 nm. The BET surface area, pore volume and average pore diameter of the nanoparticles were found to be 1322.4 m2 g−1, 1.39 cc/g and 4.2 nm respectively. The corrosion protection performance of the coatings was evaluated via Electrochemical Impedance Spectroscopy (EIS) in 3.5 % NaCl. The acrylic coating with dendrimer like silica nano containers showed improved and long-term corrosion protection than the coating without nano containers. The smart self-healing property of the coating was studied by Scanning Vibrating Electrode Technique (SVET). The SVET showed a smartness activity of DMSN by release of inhibitor triggered by corrosion phenomena in the defect area. Further, to reassert the smartness of the coating, impedance mapping of the surface was carried out at a fixed frequency.

Novel graphene/hollow polyaniline carrier with high loading of benzotriazole improves barrier and long-term self-healing properties of nanocomposite coatings

In this research, the main aim is to take the advantages of both graphene (Gr) and polyaniline (PA) in enhancing the barrier property and self-healing performance of composite coating. Herein, hollow polyaniline (HOPA) was prepared by sacrificing template method, which not only acted as a dispersant to enhance the dispersion of Gr nanosheets via the π-π interactions, but also was used as a nano container for storing benzotriazole (BTA) corrosion inhibitor. In addition, insoluble Cu-BTA complex stoppers possessed H+ ion-responsive inhibitor release property. The final release concentration of BTA in Gr/HOPA carrier was as high as 274.55 ppm, which was about 2.3 times than that of PA (120.42 ppm) due to the formation of cavity structure. From the EIS results of intact coatings, the 0.7 % of Gr/HOPA/BTA@Cu loaded composite coating exhibited a remarkable corrosion protection capability after 130 days of immersion. And the scratch test indicates that the Gr/HOPA/BTA@Cu based composite coating showed more long-term self-healing effect than that of Gr/PA/BTA@Cu/epoxy sample, which was related to the high BTA loading rate in HOPA.

Fabrication and evaluation of nanocontainers for lipophilic anticancer drug delivery in 3D in vitro model.

Presently, most of anticancer drugs are high toxic for normal cells and, and as a result, they have severe side effects. Moreover, most of the formulations are lipophilic and have poor selectivity. To overcome these limitations, various drug delivery systems could be proposed. The aim of the current study was to fabricate novel polysaccharide nanocontainers (NC) by one-step ultrasonication technique and to evaluate their accumulation efficacy and cytotoxicity in 2D (monolayer culture) and 3D (tumor spheroids) in vitro models. NC with mean sizes in a range of 340-420 nm with the core-shell structure are synthetized and characterized. The NC shell is composed from diethylaminoethyl dextran/xanthan gum polyelectrolyte complex, while the hydrophobic core was loaded with the lipophilic anticancer drug thymoquinone. To enhance NC accumulation in human breast adenocarcinoma MCF-7 cells, the NC surface was modified with poly-L-lysine (PLL) or polyethylene glycol. Cell uptake of the NC loaded with Nile Red into the tumor cells was investigated by laser scanning confocal microscopy, fluorescent flow cytometry and fluorimetry. Modification of the NC with PLL allowed to obtain the optimal drug delivery system with maximal cytotoxicity, which was tested by MTT-test. The developed NC are promising for lipophilic anticancer drug delivery.

KIT-6 Üzerinde CO2 Adsorpsiyon Davranışı ve Kinetiği Üzerine Bir Çalışma

KIT-6 mesoporous silica has been used in catalysis, nano containers, adsorption and drug delivery applications due to its original three dimensional channel network. Typically, KIT-6 is prepared from triblock copolymers as the template directing agents under acidic conditions. In this article, KIT-6 was successfully synthesized via partitioned cooperative self-assembly method. The synthesized sample was characterized using X-ray diffraction (XRD), thermogravimetry/differential thermal analysis (TG/DTA) and N2 adsorption/desorption. The characterization methods demonstrated that the synthesized sample is ordered KIT-6 mesoporous silica with a high surface area (605.93 m2 g-1), pore volume (0.58 cm3 g-1), and good thermal stability. The CO2 adsorption studies of the sample were performed at different temperatures (25, 75 and 100°C). The maximum adsorption capacity (0.65 mmol g-1) was observed at 25°C adsorption temperature. In addition, it was determined that the adsorption capacity of KIT-6 decreases with increasing adsorption temperature. This study also presents the investigation of the CO2 adsorption kinetics on KIT-6 using the first order and the second order models. The kinetic data for the CO2 adsorption on the sample conformed to the second order model. The activation energy (Ea) was calculated as 18.75 kJ mol-1 from Arrhenious plot for CO2 adsorption on KIT-6 mesoporous silica. Moreover, the regenerability and cyclic stability of KIT-6 mesoporous silica was determined using TG/DTA analysis. From the analysis results, it was clearly seen that the ordered mesoporus silica has perfect cyclic stability of 94% after 4 adsorption/desorption cycle, which implies that the synthesized KIT-6 could possibly used as an adsorbent in the CO2 adsorption.

Hydrogen effect on the high-nickel surface steel properties during machining and wear with lubricants

Purpose: The aim of the proposed research is to investigate the hydrogen effect on the high-nickel steel surface properties changing during machining and wear with participation of lubricant-cooling environments. Design/methodology/approach: The approach of the fracture mechanics and physicalchemical methods surface properties investigation was used to formulate the conclusions. Applying of lubricant-cooling (liquid, solid, gaseous) technological environments (LCTE) has change the morphology of chips and roughness of contact 23Ni1Mo3Ti steel surfaces depending on the experimentally fixed hydrogen concentrations (4.62…12.0 ppm). It correlates with both the roughness of the treated surface and the nature of the cutting products fragmentation: the maximum concentration of hydrogen - in the chips coincides with the minimum size of its defragmentation and reduction of the surface roughness. For nitrogen and oxygen, a similar relationship is traced poorly. Findings: On the basis of the fracture mechanics approaches it is confirmed, that in the conditions of the application of hydrogen containing (as chemical composition) (up to 12 ppm) and hydrogen accumulated (in nano container) (up to 600 ppm) LCTE, hydrogen enters the near crack initiation contact zone before fracture and taking part in changing structural material fracture mechanisms, improves its mashinning processes. Research limitations/implications: The results obtained on laboratory specimens should be tested during machining of real details made from high-nickel steel. Practical implications: The created technological approaches can be used in practice evaluation of mechanical properties and residual of modern gas turbine parts. Originality/value: It was shown, that hydrogen containing (in chemical composition) and hydrogen accumulated (in nano container) LCTE permits the hydrogen to enter in the near crack initiation contact zone before fracture and taking part in changing structural material fracture mechanisms.

Halloysite nanotubes loaded with nano silver for the sustained-release of antibacterial polymer nanocomposite scaffolds

It is challenging for antibacterial polymer scaffolds to achieve the drug sustained-release through directly coating or blending. In this work, halloysite nanotubes (HNTs), a natural aluminosilicate nanotube, were utilized as a nano container to load nano silver (Ag) into the lumen through vacuum negative-pressure suction & injection and thermal decomposition of silver acetate. Then, the nano Ag loaded HNTs (HNTs@Ag) were introduced to poly-l-lactic acidide) (PLLA) scaffolds prepared by additive manufacturing for the sustained-release of Ag+. Acting like a 'shield', the tube walls of HNTs not only retarded the erosion of external aqueous solution on internal nano Ag to generate Ag+ but also postponed the generated Ag+ to diffuse outward. The results indicated the PLLA-HNTs@Ag nanocomposite scaffolds achieved a sustained-release of Ag+ over 28 days without obvious initial burst release. Moreover, the scaffolds exhibited a long-lasting antibacterial property without compromising the cytocompatibility. Besides, the degradation properties, biomineralization ability and mechanical properties of the scaffolds were increased. This study suggests the potential application of inorganic nanotubes as drug carrier for the sustained-release of functional polymer nanocomposite scaffolds.

RETRACTED: Folic acid mediated endocytosis enhanced by modified multi stimuli nanocontainers for cancer targeting and treatment: Synthesis, characterization, in-vitro and in-vivo evaluation of therapeutic efficacy

Abstract Polymeric materials are in the epicenter of scientific research the last decade and have been used in a range of pharmaceutical and biological applications. Multifunctional polymeric materials are capable targeting agents, which can be used as controlled drug release vehicles for the enhancement of therapeutic efficacy, as well as for diagnostic purposes. A newer generation of these smart polymeric entities constitutes of smart nanocontainers (NCs), which can navigate the drug to specific areas by avoiding random distribution, and thus resulting in drug toxicity reduction. The combination of pH, thermo and redox sensitivity of the multi stimuli NCs can help to achieve specific release of the drug in the tumor area, where these sensitivity parameters can be observed. Hollow polymeric multi stimuli fluorescent tNCs based on N-(2-Hydroxypropyl)methacrylamide (HPMA) were successfully functionalized with a specific targeting moiety; folic acid, and then characterized morphologically, by scanning electron and transmission electron microscopy, as well as structurally, by Fourier-transform infrared spectroscopy. Their targeting mechanism was investigated in vitro in cervical cancer cell lines and in vivo in tumor bearing mice. According to our results the folic acid functionalized NCs targeted HeLa cells’ surface within the first 30 min of treatment. Human tumor xenografted mice (nonobese diabetic/severe combined immunodeficient) were injected with folate functionalized NCs and their tumor uptake was estimated by γ-imaging at about 3.5%. The targeting efficiency of the folate functionalized NCs was investigated directly in vivo by γ-imaging and indirectly by a tumor efficacy protocol.

P.412 Gallic acid, chlorogenic acid, ferulic acid and quercetin improve learning and memory processes in olfactory bulbectomized rats

Polymeric nanocontainers (NCs) impregnated with corrosion inhibitor benzotriazole are formed using layer-by-layer deposition of poly(acrylic acid) and poly(diallyldimethylammonium chloride) onto hematite particles in the presence of 0.1 M NaCl. Electric light scattering and electrophoresis are employed to control the formation and the size of NCs, as well as the stability of their suspensions. The inhibitor loaded NCs are incorporated into the volume of the galvanized coating during the electrodeposition of zinc on the steel substrate to ensure additional self-healing effect in the case of corrosion attack. The surface morphology and the uniformity of this composite coating as well as the lack of aggregation of the nanocontainers is demonstrated by scanning electron microscopy. The influence of NCs present in the zinc electrolyte on the cathodic and anodic processes is investigated by cyclic voltammetry. The corrosion behavior of the composite coatings at conditions of external cathodic and anodic polarization is tested with potentiodynamic measurements and the results are compared to pure zinc coatings. The composite coatings with embedded NCs revealed enhanced corrosion protection of low carbon steel in comparison with the pure zinc coatings in neutral corrosion medium.

Gold nanoparticle decorated pH-sensitive polymeric nanocontainers as a potential theranostic agent

A pH-sensitive system of hollow P(MAA-co-MBA-co-AA) nanocontainers (NCs) modified with gold nanoparticles (GNCs) has been developed for theranostic applications, drug delivery and real time monitoring through imaging. The GNCs were synthesised by the distillation precipitation copolymerization procedure followed by in situ synthesis and embodiment of gold nanoparticles on the polymeric matrix (CSNs). Separately, citrate capped gold nanoparticles (GNPs) were also synthesized and compared with the GNCs for their fluorescence and cellular localization ability. The GNCs were tested for their drug loading and release behavior in response to the anticancer drug doxorubicin (DOX) at different pH values. Sustained drug release was observed at acidic pH. The viability of MCF-7 breast cancer cells and HEK-293 human embryonic kidney cells in relation to the GNCs, GNPs, GNC@DOX and DOX was also evaluated. GNCs and GNPs at the tested concentrations did not inhibit proliferation at either cell lines, whereas the GNCs@DOX presented comparable results. Cellular migration of MCF-7 cells treated with GNCs or GNPs was evaluated through the scratch-wound healing assay but no significant inhibition was detected. GNCs’ and GNPs’ fluorescence ability was exploited for assessing cellular localization through confocal laser scanning microscopy. GNCs after only 1 h of treatment were found in the cytoplasm of MCF7 cells, whereas GNCs@DOX were localized in the nucleus; the desirable site of action of DOX.

Magnetically controlled protein nanocontainers as a drug depot for the hemostatic agent.

PurposeCurrently, there is a number of successfully implemented local hemostatic agents for external bleedings in forms of wound dressings and other topical materials. However, little has been done in the field of intravenous hemostatic agents. Here, we propose a new procedure to fabricate biocompatible protein nanocontainers (NCs) for intravenous injection allowing magneto-controllable delivery and short-term release of the hemostatic agent ε-aminocaproic acid (EACA).MethodsThe nanocontainers were synthesized by the desolvation method from bovine serum albumin (BSA) using methanol without any further crosslinking. Polyethylene glycol (PEG) was used both as a stabilization agent and for size control. Characterization of nanocontainers was performed by the transmission and scanning electron microscopy, dynamic light scattering, X-ray diffraction, and FTIR spectroscopy. Cytotoxicity was estimated using MTT assay. The dopant release from nanocontainers was measured spectrophotometrically using rhodamine B as a model molecule. The specific hemostatic activity was assessed by analyzing clot lysis and formation curve (CloFAL). Moreover, the ability for magneto targeting was estimated using the original flow setup made of a syringe pump and silicon contours.ResultsFabricated nanocontainers had an average size of 186±24 nm and were constructed from building blocks–nanoparticles with average size ranged from 10 to 20 nm. PEG shell was also observed around nanocontainers with thickness 5–10 nm. NCs were proved to be completely non-cytotoxic even at concentrations up to 8 mg BSA/mL. Uptake capacity was near 36% while release within the first day was 17%. The analysis of the CloFAL curve showed the ability of NCs to inhibit the clot lysis successfully, and the ability of magneto targeting was confirmed under flow conditions.ConclusionThe ability of synthesized NCs to deliver and release the therapeutic drug, as well as to accumulate at the desired site under the action of the magnetic field was proved experimentally.

Serum amyloid A protein as a diagnostic marker for viral infections

Polymeric nanocontainers (NCs) impregnated with corrosion inhibitor benzotriazole are formed using layer-by-layer deposition of poly(acrylic acid) and poly(diallyldimethylammonium chloride) onto hematite particles in the presence of 0.1 M NaCl. Electric light scattering and electrophoresis are employed to control the formation and the size of NCs, as well as the stability of their suspensions. The inhibitor loaded NCs are incorporated into the volume of the galvanized coating during the electrodeposition of zinc on the steel substrate to ensure additional self-healing effect in the case of corrosion attack. The surface morphology and the uniformity of this composite coating as well as the lack of aggregation of the nanocontainers is demonstrated by scanning electron microscopy. The influence of NCs present in the zinc electrolyte on the cathodic and anodic processes is investigated by cyclic voltammetry. The corrosion behavior of the composite coatings at conditions of external cathodic and anodic polarization is tested with potentiodynamic measurements and the results are compared to pure zinc coatings. The composite coatings with embedded NCs revealed enhanced corrosion protection of low carbon steel in comparison with the pure zinc coatings in neutral corrosion medium.

Proteinaceous Nano container Encapsulate Polycyclic Aromatic Hydrocarbons

Polycyclic aromatic hydrocarbons (PAHs) are toxic, mutagenic and among the most damaging chemical compounds with regard to living organisms. Because of their persistence and wide distribution removal from the environment is an important challenge. Here we report a new Nano container matrix based on the deep sea archaea-derived RHCC-Nanotube (RHCC-NT), which rapidly and preferentially binds low molecular weight PAHs. Under controlled-laboratory conditions and using fluorescence spectroscopy in combination with X-ray crystallography and MD simulations, we quantified the real-time binding of low molecular weight PAHs (2–4 rings) to our substrate. Binding coefficients ranged from 5.4 ± 1.6 (fluorene) to 32 ± 7.0 μM (acenaphthylene) and a binding capacity of 85 pmoles PAH per mg RHCC-NT, or 2.12 μmoles in a standard 25 mg sampler. The uptake rate of pyrene was calculated to be 1.59 nmol/hr∙mol RHCC-NT (at 10 C). Our results clearly show that RHCC-NT is uniquely suited as a monitoring matrix for low molecular weight PAHs.

Hybrid zinc coatings for corrosion protection of steel using polyelectrolyte nanocontainers loaded with benzotriazole

Core-shell nanocontainers (NCs) with corrosion inhibitor benzotriazole (BTA) are fabricated by electrostatic self-assembly of poly(diallyldimethylammonium chloride) (PDADMAC) and poly(acrylic acid) (PAA) on kaolinite and hematite particles. BTA is entrapped within the polyelectrolyte shell in one assembly step. The growth of the polymer shells and stability of the NCs suspensions against aggregation are followed by electric light scattering and electrophoresis The NCs loaded with BTA are incorporated into the matrix of ordinary zinc coatings by electrodeposition on steel substrates from acidic zinc sulfate solutions. The influence of the NCs on cathodic and anodic processes is analyzed in the starting zinc sulfate solution with cyclic voltammetry. The scanning electron microscopy shows random (near to uniform) distribution of the NCs in both hybrid coatings. The protective characteristics of the hybrid coatings in model medium of 5% NaCl are followed by means of potentiodynamic polarization curves, polarization resistance measurements and electrochemical impedance spectroscopy. XPS method is applied for determination of the nature of additional products appearing on the coatings as a result of the corrosion treatment. Both hybrid zinc coatings reveal improved corrosion protection of steel as compared to the pure zinc coating, the coating with kaolinite-based NCs showing better protective characteristics in comparison with the one incorporating hematite NCs.

In vivo toxicity study of quatro stimuli nanocontainers in pregnant rats: Gestation, parturition and offspring evaluation

The aim of the present study was to investigate the impact of intravenous administration of newly fabricated nanocontainers (NCs) on the last third of pregnancy in rats. Fifteen pregnant 3-month-old Wistar rats were separated into 3 groups. On the 15th and 17th day of pregnancy all animals received an intravenous administration of 1 ml of 15 mg of NCs (Group A), 1 ml of 5 mg NCs (Group B) while Control group received 1 ml of 0.9% NaCl. On the 14th and 17th of pregnancy ultrasonography was performed and the parameters evaluated were the width of placenta, the length and width of the embryonic sac, the foetus length and the heart rate. On parturition the number of pups per dam was evaluated. Half of the pups were euthanised the day after parturition and their liver and kidney was histologically evaluated and for the rest of the pups the body growth curve was evaluated until the age of 14 week. At the end of the 14th week the remaining pups were euthanised and their liver and kidney was histologically evaluated. At weaning the dams were euthanised and their liver and kidney was histologically evaluated. Ultrasonography: Baseline measurements of the width of placenta, the length and width of embryonic sac, the foetus length and the heart rate on the 14th day of pregnancy, revealed no statistical significant differences between groups. Comparison of the same values on the 17th day of pregnancy after 2 intravenous administrations of NCs showed no statistical significant effect on the respective parameters. The administration of NCs had no impact on the mean number of pups per dam. Additionally, no impact of the NCs on the body weights of the pups was observed on the 1st day after parturition. Moreover, comparisons between groups, for both sexes showed no difference on growth rate. During the histological evaluation no inflammatory, degenerative or neoplastic lesions were observed as far as the newborn, adult offspring and dams were concerned. According to our results no toxic impact of the low and high doses of the NCs was observed on the parameters selected to be evaluated.

Polyelectrolyte-modified kaolinite nanocontainers for entrapment of corrosion inhibitor benzotriazole

Kaolinite nanoparticles are encapsulated with polymers for application as nanocontainers (NCs) that can release the entrapped corrosion inhibitor benzotriazole (BTA) at neutral conditions. The NCs are prepared using layer-by-layer assembly of poly(diallyldimethyl ammonium chloride) (PDADMAC) and poly(acrylic acid) (PAA) on kaolinite surface at different pH and salt conditions. The inhibitor is entrapped within polyelectrolyte multilayer in the assembly step. In the absence of salt, stable NCs with BTA are prepared at pH 8/5 for adsorption of PDADMAC and PAA layers, respectively. In the presence of 0.01 M NaCl, stable suspension of NCs cannot be prepared at these pH values. Instead, stabilized suspension of NCs is obtained at pH 8/8 of both polyelectrolyte solutions, which is attributed to the stronger electrostatic interactions between PDADMAC and more highly charged PAA chains. Larger amount of BTA is measured in the NCs prepared in the presence of salt.

Nanocontainers-enhanced self-healing Ni coating for corrosion protection of Mg alloy

Self-healing coating based on nanocontainers (NCs) has been emerging as a great strategy to improve the anticorrosion ability of susceptible metal substrate. However, all the research referred to such smart coating to date is focus on organic coating instead of metallic coating. To fill this gap, 2-mercaptobenzothiazole (MBT) loaded porous hollow SiO2 NCs are synthesized and incorporated successfully into an electroless Ni coating on Mg alloy in this work. The surface morphologies and the loading properties of the NCs are characterized by scanning electron microscopy, transmission electron microscopy, ultraviolet–visible spectrophotometer, X-ray photoelectron spectroscopy, and Fourier transform infrared spectroscopy. The favorable performance of Ni coating after incorporation of NCs is demonstrated by potentiodynamic polarization (PDP), linear polarization, and electrochemical impedance spectroscopy. Based on the results of PDP test, the corrosion current density (i c) of the MBT@NCs (MNCs)-engineered Ni coating reduces slightly from 6.4 to 5.4 μA cm−2 after immersion in a corrosive media, while the value for MNCs-free coating increases by almost a factor of ten from 6.8 to 67.4 μA cm−2. Our findings demonstrate the possibility of using corrosion inhibitors loaded NCs to enhance the corrosion resistance of a metallic coating and give new perspectives for functionalization of a metallic coating with nanomaterials.

Application of amine-functionalized MCM-41 as pH-sensitive nano container for controlled release of 2-mercaptobenzoxazole corrosion inhibitor

In the present study, a pH-responsive corrosion inhibitor system is designed based on aminopropylated MCM-41 as nanocontainer and 2-mercaptobenzoxazole (MBOH) as anti-corrosion agent. This hybrid material shows long-term inhibition capability in 3.5wt% NaCl solution for Cu and stainless steel. The pH-sensitive composite was prepared via grafting the aminopropyl groups to the surface of mesoporous MCM-41 followed by loading of anti-corrosion agent. The XRD, FT-IR, BET, TGA, TEM, and SEM techniques were used to study the morphological and structural properties of the nanocontainer. The loading and releasing properties of nanocontainer were studied using UV–Visible spectroscopy. The results demonstrate that the minimum release rate of MBOH occurs in neutral condition and that with increase of acidity or basicity of the media, the release rate of the corrosion inhibitor from mesoporous silica increases. The self-healing property of nanocontainer was evaluated by electrochemical impedance spectroscopy (EIS). The results of the approach in this paper can be used in many applications where active corrosion protection of materials is required.